Compounds > 4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol
Page last updated: 2024-09-03

4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol and 1-methyl-3-isobutylxanthine

4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol has been researched along with 1-methyl-3-isobutylxanthine in 1 studies

Compound Research Comparison

Studies
(4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol)		Trials
(4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol)		Recent Studies (post-2010)
(4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
27055,1485279

Protein Interaction Comparison

ProteinTaxonomy4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barger, SW; Li, GG; McMullan, SM; Phanavanh, B1

Other Studies

1 other study(ies) available for 4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol and 1-methyl-3-isobutylxanthine

ArticleYear
Metabotropic glutamate receptors inhibit microglial glutamate release.
    ASN neuro, 2012, Aug-07, Volume: 4, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Animals, Newborn; Brain; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Glutamic Acid; Lipopolysaccharides; Neuroglia; Nitrites; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger

2012