4-((2-chloroethyl) (2-mesyloxyethyl)amino)benzoic acid has been researched along with 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid in 3 studies
| Studies (4-((2-chloroethyl) (2-mesyloxyethyl)amino)benzoic acid) | Trials (4-((2-chloroethyl) (2-mesyloxyethyl)amino)benzoic acid) | Recent Studies (post-2010) (4-((2-chloroethyl) (2-mesyloxyethyl)amino)benzoic acid) | Studies (4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid) | Trials (4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid) | Recent Studies (post-2010) (4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid) |
|---|---|---|---|---|---|
| 6 | 1 | 0 | 21 | 5 | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niculescu-Duvaz, I; Pedley, RB; Springer, CJ | 1 |
| Blakey, DC; Boyle, FT; Burke, PJ; Connors, TA; Davies, DH; Dowell, RI; Hadley, EM; Mauger, AB; Melton, RG; Springer, CJ | 1 |
| Davies, LC; Friedlos, F; Hedley, D; Martin, J; Ogilvie, LM; Scanlon, IJ; Springer, CJ | 1 |
3 other study(ies) available for 4-((2-chloroethyl) (2-mesyloxyethyl)amino)benzoic acid and 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid
| Article | Year |
|---|---|
Novel prodrugs of alkylating agents derived from 2-fluoro- and 3-fluorobenzoic acids for antibody-directed enzyme prodrug therapy.
Topics: Alkylating Agents; Antibodies, Monoclonal; Benzoates; Cell Line; Cell Survival; gamma-Glutamyl Hydrolase; Kinetics; Prodrugs; Substrate Specificity | 1994 |
New mustard prodrugs for antibody-directed enzyme prodrug therapy: alternatives to the amide link.
Topics: Aniline Mustard; Antineoplastic Agents; Cell Death; Cell Division; Colorectal Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunotoxins; Molecular Structure; Prodrugs; Tumor Cells, Cultured | 1996 |
Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Fluorine; gamma-Glutamyl Hydrolase; Humans; Mice; Mice, Nude; Mustard Compounds; Neoplasm Transplantation; Prodrugs; Structure-Activity Relationship; Transplantation, Heterologous | 2005 |