Page last updated: 2024-09-04

4(5)-2-(2,6-dimethylphenyl)ethylimidazole and clonidine

4(5)-2-(2,6-dimethylphenyl)ethylimidazole has been researched along with clonidine in 2 studies

Compound Research Comparison

Studies
(4(5)-2-(2,6-dimethylphenyl)ethylimidazole)
Trials
(4(5)-2-(2,6-dimethylphenyl)ethylimidazole)
Recent Studies (post-2010)
(4(5)-2-(2,6-dimethylphenyl)ethylimidazole)
Studies
(clonidine)
Trials
(clonidine)
Recent Studies (post-2010) (clonidine)
60013,6922,0441,394

Protein Interaction Comparison

ProteinTaxonomy4(5)-2-(2,6-dimethylphenyl)ethylimidazole (IC50)clonidine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.101
Alpha-2B adrenergic receptorHomo sapiens (human)0.0353
Alpha-2C adrenergic receptorHomo sapiens (human)0.0115
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)5.365
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0173
Alpha-1D adrenergic receptorHomo sapiens (human)1.21
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)5.365
Alpha-2A adrenergic receptorBos taurus (cattle)0.002
NischarinRattus norvegicus (Norway rat)0.3662

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kärki, NT; Puurunen, J; Ruskoaho, H; Savola, JM1
Kaipiainen, S; Kärki, N; Puurunen, J; Ruskoaho, H; Savola, JM1

Other Studies

2 other study(ies) available for 4(5)-2-(2,6-dimethylphenyl)ethylimidazole and clonidine

ArticleYear
Peripheral cardiovascular alpha- and beta-adrenergic effects of some hypotensive and bradycardic arylalkyl imidazole derivatives in the rat.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart; Imidazoles; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine

1985
The cardiovascular effects of MPV 295 [4(5)-2-(2,6-dimethylphenyl)ethylimidazole], a new antihypertensive agent with alpha 2-adrenoceptor agonistic properties.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 322, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Cats; Clonidine; Heart Rate; Imidazoles; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1983