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4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine and cocaine

4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine has been researched along with cocaine in 1 studies

Compound Research Comparison

Studies
(4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine)
Trials
(4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine)
Recent Studies (post-2010)
(4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine)
Studies
(cocaine)
Trials
(cocaine)
Recent Studies (post-2010) (cocaine)
90132,4611,0969,400

Protein Interaction Comparison

ProteinTaxonomy4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine (IC50)cocaine (IC50)
Amyloid-beta precursor proteinHomo sapiens (human)0.338
Fatty acid-binding protein, heartHomo sapiens (human)0.367
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0855
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0855
DRattus norvegicus (Norway rat)5.7544
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)5.7544
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.2861
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.4321
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0855
Sodium-dependent serotonin transporterHomo sapiens (human)0.5442
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.8885
Sodium-dependent dopamine transporter Homo sapiens (human)0.3796
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.541
Sodium-dependent dopamine transporterMus musculus (house mouse)0.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.05
TransporterRattus norvegicus (Norway rat)3.2277

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castagnoli, N; Dormehl, IC; Hugo, N; Keeve, R; Müller-Gärtner, HW; Neumeyer, JL; Oliver, DW; Rossouw, NT; Van der Schyf, CJ1

Other Studies

1 other study(ies) available for 4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine and cocaine

ArticleYear
Effect of the haloperidol tetrahydropyridine metabolite 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6- tetrahydropyridine on dopamine receptor and transporter binding. A nonhuman primate 123I-iodobenzamide and 2 beta-carbomethoxy-3 beta-(4-
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:6

    Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Haloperidol; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Pyrrolidines; Receptors, Dopamine; Tomography, Emission-Computed, Single-Photon

1997