3-tyrosine and 3-hydroxybenzylhydrazine

3-tyrosine has been researched along with 3-hydroxybenzylhydrazine* in 1 studies

Other Studies

1 other study(ies) available for 3-tyrosine and 3-hydroxybenzylhydrazine

Article	Year
A new radiopharmaceutical for the cerebral dopaminergic presynaptic function: 6-radioiodinated L-meta-tyrosine. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:1 Geometric isomers of radioiodinated L-meta-tyrosine, 6-[I-125]iodo-and 4-[1-125]iodo-L-meta-tyrosine (6-I-L-mTyr, 4-I-L-mTyr) were separated by high-performance liquid chromatography . Both 6-I- and 4-I-L-mTyr had high energy-dependent brain accumulation. 6-I- and 4-I-L-mTyr were also metabolically stable and were rapidly excreted through the urine. 6-I-L-mTyr had a predilection for the cerebral aromatic L-amino acid decarboxylase (DOPA decarboxylase), the final enzyme of dopamine biosynthesis. 6-Radioiodinated L-mTyr is a new radiopharmaceutical that can be both useful in assessing cerebral amino acid transport mechanism and quantifying metabolically active DOPA decarboxylase. Topics: Animals; Autoradiography; Brain; Dopamine; Enzyme Inhibitors; Hydrazines; Iodine Radioisotopes; Isomerism; Male; Pancreas; Presynaptic Terminals; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Tyrosine	2000

Article

Year

A new radiopharmaceutical for the cerebral dopaminergic presynaptic function: 6-radioiodinated L-meta-tyrosine.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:1

Geometric isomers of radioiodinated L-meta-tyrosine, 6-[I-125]iodo-and 4-[1-125]iodo-L-meta-tyrosine (6-I-L-mTyr, 4-I-L-mTyr) were separated by high-performance liquid chromatography . Both 6-I- and 4-I-L-mTyr had high energy-dependent brain accumulation. 6-I- and 4-I-L-mTyr were also metabolically stable and were rapidly excreted through the urine. 6-I-L-mTyr had a predilection for the cerebral aromatic L-amino acid decarboxylase (DOPA decarboxylase), the final enzyme of dopamine biosynthesis. 6-Radioiodinated L-mTyr is a new radiopharmaceutical that can be both useful in assessing cerebral amino acid transport mechanism and quantifying metabolically active DOPA decarboxylase.

Topics: Animals; Autoradiography; Brain; Dopamine; Enzyme Inhibitors; Hydrazines; Iodine Radioisotopes; Isomerism; Male; Pancreas; Presynaptic Terminals; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Tyrosine

2000