3-tritylthio-l-alanine has been researched along with sb 743921 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Good, JA; Kaan, HY; Kozielski, F; MacKay, SP; Podgórski, D; Rath, O; Talapatra, SK; Wang, F | 1 |
| El-Nassan, HB | 1 |
| Anthony, NG; Kozielski, F; Mackay, SP; Talapatra, SK | 1 |
1 review(s) available for 3-tritylthio-l-alanine and sb 743921
| Article | Year |
|---|---|
Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Discovery; Humans; Kinesins; Models, Molecular; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2013 |
1 trial(s) available for 3-tritylthio-l-alanine and sb 743921
| Article | Year |
|---|---|
Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.
Topics: Allosteric Regulation; Benzamides; Chromones; Humans; Kinesins; Kinetics; Mitosis; Models, Molecular | 2013 |
1 other study(ies) available for 3-tritylthio-l-alanine and sb 743921
| Article | Year |
|---|---|
Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.
Topics: Animals; Antineoplastic Agents; Benzamides; Butylamines; Cell Line, Tumor; Chromones; Cysteine; Kinesins; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Structure-Activity Relationship; Transplantation, Heterologous | 2013 |