Compounds > 3-pyridyl pinacidil
Page last updated: 2024-08-23

3-pyridyl pinacidil and pinacidil

3-pyridyl pinacidil has been researched along with pinacidil in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arrigoni-Martelli, E; Nielsen, CK; Petersen, HJ1
Manley, PW; Quast, U1
Komatsu, K; Matsushita, Y; Moriguchi, I1
Ebisu, H; Eda, M; Fukaya, C; Gohda, M; Hihara, M; Matzno, S; Nakamura, N; Okada, T; Sakashita, H; Takemoto, T1
Bemis, KG; Schelm, JA; Simpson, PJ; Smallwood, JK1
Das, B; Sarkar, C1

Other Studies

6 other study(ies) available for 3-pyridyl pinacidil and pinacidil

ArticleYear
Synthesis and hypotensive activity of N-alkyl-N"-cyano-N'-pyridylguanidines.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:8

    Topics: Animals; Antihypertensive Agents; Dogs; Female; Guanidines; Hypertension; Lethal Dose 50; Mice; Rats; Structure-Activity Relationship

1978
Structure-activity studies of potassium channel opening in pinacidil-type cyanoguanidines, nitroethenediamines, thioureas, and ureas.
    Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12

    Topics: Animals; Diamines; Guanidines; Ion Channel Gating; Male; Molecular Conformation; Molecular Structure; Muscle Contraction; Pinacidil; Portal Vein; Potassium Channels; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Structure-Activity Relationship; Thiourea; Urea; Vasodilator Agents

1992
Adaptive least-squares method applied to structure--activity correlation of hypotensive N-alkyl-N''-cyano-N'-pyridylguanidines.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Antihypertensive Agents; Guanidines; Mathematics; Models, Theoretical; Statistics as Topic; Structure-Activity Relationship

1980
Novel potassium channel openers: synthesis and pharmacological evaluation of new N-(substituted-3-pyridyl)-N'-alkylthioureas and related compounds.
    Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1

    Topics: 4-Aminopyridine; Amifampridine; Animals; Antihypertensive Agents; Biomechanical Phenomena; Glyburide; Guanidines; Hypertension; Male; Molecular Structure; Norbornanes; Pinacidil; Portal Vein; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship

1994
Effect of activation of ATP-dependent potassium channels with (-)-pinacidil and (-)-3-pyridyl pinacidil on infarct size in a canine model of ischemia-reperfusion injury.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5

    Topics: Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Guanidines; Hemodynamics; Male; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; Peroxidase; Pinacidil; Potassium Channels; Vasodilator Agents

1993
Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Blood Pressure; Decanoic Acids; Electrocardiography; Heart Rate; Hydroxy Acids; Ion Channel Gating; Male; Membrane Proteins; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Oxidative Stress; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Sarcolemma; Sulfonamides; Survival Rate; Thiourea

2003