3-propylamino-5-hydroxychroman has been researched along with buspirone in 4 studies
| Studies (3-propylamino-5-hydroxychroman) | Trials (3-propylamino-5-hydroxychroman) | Recent Studies (post-2010) (3-propylamino-5-hydroxychroman) | Studies (buspirone) | Trials (buspirone) | Recent Studies (post-2010) (buspirone) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 2,096 | 351 | 382 |
| Protein | Taxonomy | 3-propylamino-5-hydroxychroman (IC50) | buspirone (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.025 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 1.75 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.024 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.323 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 2.125 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| D | Rattus norvegicus (Norway rat) | 0.12 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0266 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 4 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.077 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.286 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.016 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 2.125 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.75 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2055 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.9811 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.025 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.7 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.2666 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adam, G; Caignard, DH; Guardiola-Lemaître, B; Guillaumet, G; Pfeiffer, B; Podona, T; Renard, P | 1 |
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Archer, T; Dyr, W; Järbe, T; Kostowski, W; Krzascik, P | 1 |
| Kostowski, W; Pałejko, W; Płaźnik, A; Stefański, R | 1 |
4 other study(ies) available for 3-propylamino-5-hydroxychroman and buspirone
| Article | Year |
|---|---|
3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.
Topics: Animals; Anti-Anxiety Agents; Benzopyrans; Binding Sites; Brain; Columbidae; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship | 1994 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
5-Hydroxytryptamine1A receptor agonists in animal models of depression and anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Buspirone; Chromans; Depression; Disease Models, Animal; Electric Stimulation; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Serotonergic mechanisms in the nucleus accumbens affected by chronic desipramine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Chromans; Desipramine; Dose-Response Relationship, Drug; Methysergide; Microinjections; Nucleus Accumbens; Pindolol; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |