Page last updated: 2024-09-03

3-propylamino-5-hydroxychroman and 8-hydroxy-2-(di-n-propylamino)tetralin

3-propylamino-5-hydroxychroman has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 6 studies

Compound Research Comparison

Studies
(3-propylamino-5-hydroxychroman)
Trials
(3-propylamino-5-hydroxychroman)
Recent Studies (post-2010)
(3-propylamino-5-hydroxychroman)
Studies
(8-hydroxy-2-(di-n-propylamino)tetralin)
Trials
(8-hydroxy-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
8003,5307389

Protein Interaction Comparison

ProteinTaxonomy3-propylamino-5-hydroxychroman (IC50)8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.0012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0032
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorBos taurus (cattle)0.8
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.81
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorRattus norvegicus (Norway rat)2.8959
Lysosomal alpha-glucosidaseBos taurus (cattle)0.0021

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adam, G; Caignard, DH; Guardiola-Lemaître, B; Guillaumet, G; Pfeiffer, B; Podona, T; Renard, P1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Archer, T; Dyr, W; Järbe, T; Kostowski, W; Krzascik, P1
Kostowski, W; Pałejko, W; Płaźnik, A; Stefański, R1
Caldarola-Pastuszka, M; Moore, N; Uphouse, L1
Johansson, C; Misane, I; Ogren, SO1

Other Studies

6 other study(ies) available for 3-propylamino-5-hydroxychroman and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.
    Journal of medicinal chemistry, 1994, Jun-10, Volume: 37, Issue:12

    Topics: Animals; Anti-Anxiety Agents; Benzopyrans; Binding Sites; Brain; Columbidae; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship

1994
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
5-Hydroxytryptamine1A receptor agonists in animal models of depression and anxiety.
    Pharmacology & toxicology, 1992, Volume: 71, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Buspirone; Chromans; Depression; Disease Models, Animal; Electric Stimulation; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tetrahydronaphthalenes

1992
Serotonergic mechanisms in the nucleus accumbens affected by chronic desipramine treatment.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Chromans; Desipramine; Dose-Response Relationship, Drug; Methysergide; Microinjections; Nucleus Accumbens; Pindolol; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1991
Inhibitory effects of the 5-HT1A agonists, 5-hydroxy- and 5-methoxy-(3-di-n-propylamino)chroman, on female lordosis behavior.
    Neuropharmacology, 1993, Volume: 32, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromans; Female; Injections; Male; Piperazines; Posture; Proestrus; Rats; Rats, Inbred F344; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus

1993
Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat.
    British journal of pharmacology, 1998, Volume: 125, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Behavior, Animal; Chromans; DOM 2,5-Dimethoxy-4-Methylamphetamine; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998