Page last updated: 2024-09-03

3-propylamino-5-hydroxychroman and 1-(3-trifluoromethylphenyl)piperazine

3-propylamino-5-hydroxychroman has been researched along with 1-(3-trifluoromethylphenyl)piperazine in 2 studies

Compound Research Comparison

Studies
(3-propylamino-5-hydroxychroman)
Trials
(3-propylamino-5-hydroxychroman)
Recent Studies (post-2010)
(3-propylamino-5-hydroxychroman)
Studies
(1-(3-trifluoromethylphenyl)piperazine)
Trials
(1-(3-trifluoromethylphenyl)piperazine)
Recent Studies (post-2010) (1-(3-trifluoromethylphenyl)piperazine)
800281723

Protein Interaction Comparison

ProteinTaxonomy3-propylamino-5-hydroxychroman (IC50)1-(3-trifluoromethylphenyl)piperazine (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.57
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.57
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.29
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.61
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.15
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.039
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.57

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Caldarola-Pastuszka, M; Moore, N; Uphouse, L1

Other Studies

2 other study(ies) available for 3-propylamino-5-hydroxychroman and 1-(3-trifluoromethylphenyl)piperazine

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Inhibitory effects of the 5-HT1A agonists, 5-hydroxy- and 5-methoxy-(3-di-n-propylamino)chroman, on female lordosis behavior.
    Neuropharmacology, 1993, Volume: 32, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromans; Female; Injections; Male; Piperazines; Posture; Proestrus; Rats; Rats, Inbred F344; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus

1993