3-oxoglycyrrhetinic acid has been researched along with glycyrrhetinic acid in 9 studies
| Studies (3-oxoglycyrrhetinic acid) | Trials (3-oxoglycyrrhetinic acid) | Recent Studies (post-2010) (3-oxoglycyrrhetinic acid) | Studies (glycyrrhetinic acid) | Trials (glycyrrhetinic acid) | Recent Studies (post-2010) (glycyrrhetinic acid) |
|---|---|---|---|---|---|
| 10 | 0 | 6 | 102 | 0 | 67 |
| Protein | Taxonomy | 3-oxoglycyrrhetinic acid (IC50) | glycyrrhetinic acid (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 4.9 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Rattus norvegicus (Norway rat) | 0.09 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Homo sapiens (human) | 0.1853 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Mus musculus (house mouse) | 0.0124 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 2 | Rattus norvegicus (Norway rat) | 0.36 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 2 | Homo sapiens (human) | 0.1035 | |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | 9.6 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 0.5495 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.5248 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, CF; Lin, CN; Liou, YT; Maitraie, D; Tu, HY; Wang, JP; Wei, BL; Yang, SC | 1 |
| Amer, H; Beseda, I; Classen-Houben, D; Czollner, L; Da Cunha, T; Del Ruiz-Ruiz, MC; Gaware, R; Jordis, U; Khunt, R; Kosma, P; Mereiter, K; Odermatt, A; Shah, PS; Stanetty, C | 1 |
| Classen-Houben, D; Cunha, TD; Czollner, L; Gaware, R; Jordis, U; Koller, I; Kosma, P; Odermatt, A; Shah, P; Stanetty, C | 1 |
| Classen-Houben, D; Czollner, L; Da Cunha, T; Gaware, R; Jordis, U; Khunt, R; Kosma, P; Kratschmar, DV; Odermatt, A; Stanetty, C | 1 |
| Hour, TC; Huang, AM; Lin, CN; Lin, KW; Pu, YS; Yang, SC | 1 |
| Csuk, R; Kluge, R; Schwarz, S; Siewert, B; Ströhl, D | 1 |
| Chen, H; Chen, JJ; Geng, CA; Huang, XY; Luo, J; Ma, YB; Wang, LJ; Zhang, XM | 1 |
| Ge, GB; Hao, DC; Hou, J; Jin, Q; Li, YG; Wang, P; Yang, L; Zhou, K; Zou, LW | 1 |
| Archo, S; Kaur, S; Kumar, A; Naikoo, SH; Singh, B; Singh, CP; Tasduq, SA | 1 |
9 other study(ies) available for 3-oxoglycyrrhetinic acid and glycyrrhetinic acid
| Article | Year |
|---|---|
Synthesis, anti-inflammatory, and antioxidant activities of 18beta-glycyrrhetinic acid derivatives as chemical mediators and xanthine oxidase inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line, Tumor; Enzyme Inhibitors; Glycyrrhetinic Acid; Lipopolysaccharides; Mice; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Superoxides; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2009 |
Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Crystallography, X-Ray; Glycyrrhetinic Acid; Humans; Metabolic Diseases; Models, Molecular | 2010 |
Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Hydroxamic Acids; Rats; Structure-Activity Relationship | 2010 |
Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Azepines; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Hydroxamic Acids; Structure-Activity Relationship; Urea | 2011 |
18β-Glycyrrhetinic acid derivatives induced mitochondrial-mediated apoptosis through reactive oxygen species-mediated p53 activation in NTUB1 cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Humans; Membrane Potential, Mitochondrial; Mitochondria; Molecular Conformation; Reactive Oxygen Species; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2011 |
Synthesis and antitumor activity of ring A modified glycyrrhetinic acid derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chemistry Techniques, Synthetic; Glycyrrhetinic Acid; Humans; Inhibitory Concentration 50 | 2011 |
Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents.
Topics: Antiviral Agents; DNA Replication; DNA, Viral; Glycyrrhetinic Acid; Hepatitis B virus; Structure-Activity Relationship; Virus Replication | 2012 |
Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2.
Topics: Carboxylesterase; Drug Design; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Molecular Docking Simulation; Structure-Activity Relationship | 2016 |
Photoprotective effect of 18β-glycyrrhetinic acid derivatives against ultra violet (UV)-B-Induced skin aging.
Topics: Antioxidants; Benzylidene Compounds; Collagen; Fibroblasts; Humans; Skin; Skin Aging; Ultraviolet Rays | 2022 |