Page last updated: 2024-09-02

3-oxoglycyrrhetinic acid and acetylglycyrrhetinic acid

3-oxoglycyrrhetinic acid has been researched along with acetylglycyrrhetinic acid in 5 studies

Compound Research Comparison

Studies
(3-oxoglycyrrhetinic acid)
Trials
(3-oxoglycyrrhetinic acid)
Recent Studies (post-2010)
(3-oxoglycyrrhetinic acid)
Studies
(acetylglycyrrhetinic acid)
Trials
(acetylglycyrrhetinic acid)
Recent Studies (post-2010) (acetylglycyrrhetinic acid)
10061004

Protein Interaction Comparison

ProteinTaxonomy3-oxoglycyrrhetinic acid (IC50)acetylglycyrrhetinic acid (IC50)
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)4.622
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)3.78
Corticosteroid 11-beta-dehydrogenase isozyme 2Homo sapiens (human)2.0327

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amer, H; Beseda, I; Classen-Houben, D; Czollner, L; Da Cunha, T; Del Ruiz-Ruiz, MC; Gaware, R; Jordis, U; Khunt, R; Kosma, P; Mereiter, K; Odermatt, A; Shah, PS; Stanetty, C1
Classen-Houben, D; Cunha, TD; Czollner, L; Gaware, R; Jordis, U; Koller, I; Kosma, P; Odermatt, A; Shah, P; Stanetty, C1
Classen-Houben, D; Czollner, L; Da Cunha, T; Gaware, R; Jordis, U; Khunt, R; Kosma, P; Kratschmar, DV; Odermatt, A; Stanetty, C1
Chen, H; Chen, JJ; Geng, CA; Huang, XY; Luo, J; Ma, YB; Wang, LJ; Zhang, XM1
Ge, GB; Hao, DC; Hou, J; Jin, Q; Li, YG; Wang, P; Yang, L; Zhou, K; Zou, LW1

Other Studies

5 other study(ies) available for 3-oxoglycyrrhetinic acid and acetylglycyrrhetinic acid

ArticleYear
Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Crystallography, X-Ray; Glycyrrhetinic Acid; Humans; Metabolic Diseases; Models, Molecular

2010
Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Hydroxamic Acids; Rats; Structure-Activity Relationship

2010
Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Azepines; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Hydroxamic Acids; Structure-Activity Relationship; Urea

2011
Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents.
    Bioorganic & medicinal chemistry letters, 2012, May-15, Volume: 22, Issue:10

    Topics: Antiviral Agents; DNA Replication; DNA, Viral; Glycyrrhetinic Acid; Hepatitis B virus; Structure-Activity Relationship; Virus Replication

2012
Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Carboxylesterase; Drug Design; Enzyme Inhibitors; Glycyrrhetinic Acid; Humans; Molecular Docking Simulation; Structure-Activity Relationship

2016