3-nitropropionic acid has been researched along with malonic acid in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 14 (58.33) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Derr-Yellin, E; Nicklas, WJ; Zeevalk, GD | 1 |
| Beal, MF; Henshaw, DR; Matthews, RT; Schulz, JB | 1 |
| Brouillet, E; Guyot, MC; Hantraye, P; Mazière, M; Palfi, S; Stutzmann, JM | 1 |
| Beal, MF; Ferrante, RJ; Jenkins, BG; Kaddurah-Daouk, R; Matthews, RT; Rosen, BR; Yang, L | 1 |
| Geddes, JW; Jakel, RJ; Maragos, WF; Pang, Z | 1 |
| Bruce-Keller, AJ; Mattson, MP; McFall, R; Umberger, G | 1 |
| Chesnut, MD; Jakel, RJ; Maragos, WF; Tillman, PA | 1 |
| Andersen, JK; Andreassen, OA; Beal, MF; Bogdanov, M; Dedeoglu, A; Ferrante, RJ; Jiang, D; Klivenyi, P; Lancelot, E; Mueller, G | 1 |
| Chesnut, MD; Dwoskin, LP; Geddes, JW; Jakel, RJ; Maragos, WF | 1 |
| Andreassen, OA; Beal, MF; Dedeoglu, A; Ferrante, RJ; Friedlander, RM; Hughes, DB; Klivenyi, P; Ona, VO | 1 |
| Albers, DW; Andreassen, OA; Beal, MF; Carlson, EJ; Dedeoglu, A; Epstein, CJ; Ferrante, RJ; Klivenyi, P | 1 |
| Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Giroud, M; Marie, C; Mossiat, C | 1 |
| Chesnut, MD; Dwoskin, LP; Maragos, WF; Zhu, J | 1 |
| Andreassen, OA; Beal, MF; Dedeoglu, A; Dillmann, WH; Ferrante, RJ | 1 |
| Beal, MF; Browne, SE; Bubber, P; Calingasan, NY; Gardian, G; Gibson, GE; Klivenyi, P; Patel, MS; Starkov, AA; Yang, L | 1 |
| Castilho, RF; Kowaltowski, AJ; Maciel, EN; Rodrigues, JM; Schwalm, FD; Souza, DO; Vercesi, AE; Wajner, M | 1 |
| Beal, MF; Bizat, N; Brouillet, E; Joh, TH; Kiaei, M; Mischak, RP; Sugama, S; Yang, L | 1 |
| Calkins, MJ; Chan, K; Jakel, RJ; Johnson, DA; Johnson, JA; Kan, YW | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Abeliovich, A; Beal, MF; Cleren, C; Ferrante, RJ; Gardian, G; Klivenyi, P; Kowall, NW; Siwek, D; Starkov, A; Yang, L | 1 |
| Castilho, RF; Maciel, EN; Mirandola, SR; Saad, LO | 1 |
| Brunet, N; Calderó, J; Esquerda, JE; Tarabal, O | 1 |
| Chen, CL; Chen, YR; He, G; Hu, K; Liu, B; Swartz, HM; Zhu, X | 1 |
| Gao, F; Jiang, C; Li, X; Lu, S; Meng, L; Xu, J; Zhang, J; Zhu, W | 1 |
24 other study(ies) available for 3-nitropropionic acid and malonic acid
| Article | Year |
|---|---|
Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade.
Topics: Animals; Cells, Cultured; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Malonates; Mesencephalon; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anticonvulsants; Coenzymes; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Lamotrigine; Male; Malonates; Memantine; Mitochondria; Nervous System Diseases; Neuroprotective Agents; Neurotoxins; Niacinamide; Nitro Compounds; Nitrogen Oxides; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Spin Labels; Thallium; Triazines; Ubiquinone | 1996 |
Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats.
Topics: Animals; Antihypertensive Agents; Corpus Striatum; Injections, Intraperitoneal; Male; Malonates; Microinjections; Movement Disorders; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Riluzole; Succinate Dehydrogenase; Survival Analysis | 1997 |
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Antineoplastic Agents; Creatine; Creatinine; Disease Models, Animal; Energy Metabolism; Free Radicals; Huntington Disease; Lactates; Male; Malonates; Neostriatum; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Tyrosine | 1998 |
6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions.
Topics: Animals; Antihypertensive Agents; Corpus Striatum; Denervation; Male; Malonates; Mitochondria; Nerve Degeneration; Neural Pathways; Neurotoxins; Nitro Compounds; Oxidative Stress; Oxidopamine; Propionates; Rats; Rats, Sprague-Dawley; Substantia Nigra; Succinate Dehydrogenase; Sympatholytics | 1998 |
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Brain Diseases; Corpus Striatum; Diet; Energy Intake; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Malonates; Maze Learning; Memory; Mitochondria; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Visual Cortex | 1999 |
Clorgyline and deprenyl attenuate striatal malonate and 3-nitropropionic acid lesions.
Topics: Animals; Clorgyline; Corpus Striatum; Electron Transport Complex II; Male; Malonates; Mitochondria; Monoamine Oxidase Inhibitors; Multienzyme Complexes; Neurotoxins; Nitro Compounds; Oxidoreductases; Propionates; Rats; Rats, Sprague-Dawley; Reference Values; Selegiline; Succinate Dehydrogenase | 1999 |
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catechols; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Free Radicals; Glutathione; Glutathione Peroxidase; Heterozygote; Homovanillic Acid; Homozygote; Huntington Disease; Male; Malonates; Mice; Mice, Inbred Strains; Mice, Knockout; MPTP Poisoning; Nitro Compounds; Oxidative Stress; Parkinson Disease, Secondary; Propionates; Tyrosine | 2000 |
Does dopamine contribute to striatal damage caused by impaired mitochondrial function?
Topics: Animals; Apomorphine; Biological Transport; Clorgyline; Corpus Striatum; Dopamine; Malonates; Medial Forebrain Bundle; Mitochondria; Monoamine Oxidase Inhibitors; Nitro Compounds; Oxidopamine; Propionates; Rats; Selegiline; Substantia Nigra | 1999 |
Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.
Topics: Animals; Brain; Caspase 1; Crosses, Genetic; Disease Models, Animal; Female; Huntington Disease; Male; Malonates; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neostriatum; Neurotoxins; Nitro Compounds; Point Mutation; Propionates | 2000 |
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Genetic Predisposition to Disease; Gentisates; Heterozygote; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondria; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurotoxins; Nitro Compounds; Propionates; Salicylic Acid; Superoxide Dismutase | 2001 |
N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury.
Topics: 2,2'-Dipyridyl; Acute Disease; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Edema; Brain Ischemia; Carotid Arteries; Cell Death; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Injections, Intra-Arterial; Iron Chelating Agents; Male; Malonates; Microspheres; Mitochondria; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Oxidative Stress; Premedication; Propionates; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Succinate Dehydrogenase | 2001 |
Mitochondrial toxin inhibition of [(3)H]dopamine uptake into rat striatal synaptosomes.
Topics: Animals; Biological Transport; Corpus Striatum; Dopamine; Male; Malonates; Mitochondria; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium | 2002 |
Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid.
Topics: Animals; Corpus Striatum; Cytoprotection; Drug Resistance; Female; Heterozygote; Homozygote; HSP70 Heat-Shock Proteins; Male; Malonates; Mice; Mice, Transgenic; Nitro Compounds; Propionates; Succinate Dehydrogenase; Transgenes | 2002 |
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Caudate Nucleus; Cell Count; Cerebral Cortex; Corpus Striatum; Dihydrolipoamide Dehydrogenase; Disease Models, Animal; Genetic Predisposition to Disease; Heterozygote; Huntington Disease; Ketoglutarate Dehydrogenase Complex; Malonates; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Neurodegenerative Diseases; Neurons; Nitro Compounds; Parkinsonian Disorders; Propionates; Putamen; Pyruvate Dehydrogenase Complex; Substantia Nigra | 2004 |
Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition.
Topics: Animals; Antimycin A; Bongkrekic Acid; Brain; Calcimycin; Calcium; Catalase; Cell Survival; Cyclosporins; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex II; Enzyme Inhibitors; Female; In Vitro Techniques; Ionophores; Malonates; Membrane Potentials; Methylmalonic Acid; Mitochondria; NADP; Neurons; Nitro Compounds; Oxygen Consumption; PC12 Cells; Permeability; Propionates; Rats; Rotenone; Tacrolimus; Tetrazolium Salts; Thiazoles; Uncoupling Agents | 2004 |
A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Chloromethyl Ketones; Animals; BH3 Interacting Domain Death Agonist Protein; Brain; Calpain; Carrier Proteins; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Corpus Striatum; Dopamine Agents; Enzyme Inhibitors; Male; Malonates; Mesencephalon; Mice; Neurotoxins; Nitro Compounds; Propionates; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 2004 |
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.
Topics: Animals; Astrocytes; DNA-Binding Proteins; Genes, Reporter; Humans; Malonates; Mice; NF-E2-Related Factor 2; Nitro Compounds; Propionates; Succinate Dehydrogenase; Trans-Activators; Transcription, Genetic | 2005 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Mice lacking alpha-synuclein are resistant to mitochondrial toxins.
Topics: alpha-Synuclein; Animals; Malonates; Mice; Mice, Mutant Strains; Mitochondria; Neurons; Neurotoxins; Nitro Compounds; Parkinsonian Disorders; Propionates | 2006 |
Lactate dehydrogenase activity is inhibited by methylmalonate in vitro.
Topics: Animals; Brain; Cattle; Female; Humans; L-Lactate Dehydrogenase; Lactates; Liver; Malonates; Methylmalonic Acid; Muscle, Skeletal; Myocardium; Nitro Compounds; Propionates; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
Topics: Animals; Calcium Signaling; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Malonates; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Organ Culture Techniques; Propionates; Riluzole; Spinal Cord | 2009 |
Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation.
Topics: Animals; Diazoxide; Electron Transport Complex II; Electron Transport Complex III; Ion Channel Gating; Ischemic Preconditioning, Myocardial; Male; Malonates; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Nitro Compounds; Oxygen Consumption; Potassium Channels; Propionates; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2010 |
Pristane promotes anaerobic glycolysis to facilitate proinflammatory activation of macrophages and development of arthritis.
Topics: Anaerobiosis; Animals; Arthritis, Experimental; Cells, Cultured; Deoxyglucose; Glycolysis; Inflammation; Macrophages; Malonates; Mitochondria; Nitro Compounds; Propionates; Rats; Terpenes; Wortmannin | 2021 |