3-nitropropionic acid has been researched along with gamma-aminobutyric acid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (28.57) | 18.2507 |
| 2000's | 19 (67.86) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Hassel, B; Sonnewald, U | 1 |
| Beal, MF; Brouillet, E; Ferrante, RJ; Hyman, BT; Jenkins, BG; Kowall, NW; Miller, JM; Rosen, BR; Srivastava, R; Storey, E | 1 |
| Erecińska, M; Nelson, D | 1 |
| Derr-Yellin, E; Nicklas, WJ; Zeevalk, GD | 1 |
| Boireau, A; Doble, A; Meunier, M | 1 |
| Lin, W; Meyer Cameron, C; Reynolds, NC; Roerig, DL | 1 |
| Cameron, CM; Lin, W; Reynolds, NC; Roerig, DL | 1 |
| De Waal, RM; Kremer, HP; Ten Donkelaar, HJ; Verbeek, MM; Vis, JC | 1 |
| Haberek, G; Tomczyk, T; Turski, WA; Urbanska, EM; Wielosz, M; Zuchora, B | 1 |
| Gramsbergen, JB; Kornblit, B; Sandberg, M; Zimmer, J | 1 |
| Bisogno, T; Cebeira, M; Di Marzo, V; Fernández-Ruiz, J; Fezza, F; Lastres-Becker, I; Milone, A; Ramos, JA | 1 |
| Dutra-Filho, CS; Santos, CE; Souza, DO; Tasca, CI; Tavares, RG; Wajner, M | 1 |
| Berrendero, F; De Miguel, R; Fernández-Ruiz, J; Hansen, HH; Lastres-Becker, I; Manzanares, J; Pérez-Rosado, A; Ramos, JA | 1 |
| de Miguel, R; De Petrocellis, L; Di Marzo, V; Fernández-Ruiz, J; Lastres-Becker, I; Makriyannis, A | 1 |
| Beani, L; Bianchi, C; Hanau, S; Marti, M; Mela, F; Morari, M; Paganini, F; Stocchi, S; Ulazzi, L | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P; Marti, M; Morari, M; Papa, M; Picconi, B; Pisani, A; Rossi, L; Saulle, E; Tropepi, D | 1 |
| Bizat, N; Boyer, F; Brouillet, E; Fernández-Ruiz, J; Hantraye, P; Lastres-Becker, I | 1 |
| de Lago, E; Di Marzo, V; Fernández-Ruiz, J; Ramos, JA; Urbani, P | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Andres, RH; Ducray, AD; Huber, AW; Krebs, SH; Pérez-Bouza, A; Schlattner, U; Seiler, RW; Wallimann, T; Widmer, HR | 1 |
| Abdel-Naim, AB; Arafa, HM; Khalifa, AE; Tadros, MG | 1 |
| Andres, RH; Ducray, AD; Qualls, R; Schläppi, JA; Schlattner, U; Seiler, RW; Wallimann, T; Widmer, HR | 1 |
| Decio, A; Fernández-Ruiz, J; Mechoulam, R; Ramos, JA; Sagredo, O | 1 |
| Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Navarro, A; Santiago, M; Tomás-Camardiel, M; Villarán, RF | 1 |
| Deshpande, SB; Gupta, R | 1 |
| Haselden, JN; Holmes, E; Tsang, TM | 1 |
| Kalonia, H; Kumar, A; Kumar, P | 1 |
28 other study(ies) available for 3-nitropropionic acid and gamma-aminobutyric acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Selective inhibition of the tricarboxylic acid cycle of GABAergic neurons with 3-nitropropionic acid in vivo.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Neurons; Nitro Compounds; Propionates; Succinate Dehydrogenase; Succinates; Succinic Acid | 1995 |
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calbindins; Cell Adhesion Molecules, Neuronal; Corpus Striatum; Dopamine; Energy Metabolism; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Homovanillic Acid; Interneurons; Male; Mitochondria; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Reference Values; S100 Calcium Binding Protein G; Somatostatin; Substance P | 1993 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade.
Topics: Animals; Cells, Cultured; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Malonates; Mesencephalon; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
3-Nitropropionic acid exacerbates [3H]GABA release evoked by glucose deprivation in rat striatal slices.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Hypoglycemia; Isotope Labeling; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Sodium Channels; Tritium | 1996 |
Differential responses of extracellular GABA to intrastriatal perfusions of 3-nitropropionic acid and quinolinic acid in the rat.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Huntington Disease; Male; Microdialysis; Mitochondria; Neurotoxins; Nitro Compounds; Perfusion; Propionates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1997 |
Extracellular perfusion of rat brain nuclei using microdialysis: a method for studying differential neurotransmitter release in response to neurotoxins.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Electrochemistry; gamma-Aminobutyric Acid; Male; Microdialysis; Neurons; Neurotoxins; Neurotransmitter Agents; Nitro Compounds; Nucleus Accumbens; o-Phthalaldehyde; Perfusion; Propionates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Sulfhydryl Compounds | 1999 |
3-Nitropropionic acid induces a spectrum of Huntington's disease-like neuropathology in rat striatum.
Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hindlimb; Huntington Disease; Immunohistochemistry; Male; Motor Activity; Neurons; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Wistar; Somatostatin; Substance P | 1999 |
Proconvulsive effects of the mitochondrial respiratory chain inhibitor--3-nitropropionic acid.
Topics: Acetylcholine; Animals; Convulsants; Drug Interactions; Electric Stimulation; Electron Transport; Electroshock; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; Male; Mice; Nitro Compounds; Potassium Channels; Propionates; Seizures; Synaptic Transmission | 2000 |
Pyruvate protects against 3-nitropropionic acid neurotoxicity in corticostriatal slice cultures.
Topics: Adenosine Triphosphate; Animals; Culture Techniques; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Lactic Acid; Malates; Neurotoxins; Nitro Compounds; Oxaloacetic Acid; Propidium; Propionates; Pyruvic Acid; Rats; Visual Cortex | 2000 |
Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease.
Topics: Animals; Basal Ganglia; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Disease Models, Animal; Endocannabinoids; gamma-Aminobutyric Acid; Huntington Disease; Injections, Intraventricular; Male; Motor Activity; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Synaptic Transmission | 2001 |
Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro.
Topics: Adenosine Triphosphatases; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Enzyme Activation; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Wistar; Synaptic Vesicles | 2001 |
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Endocannabinoids; gamma-Aminobutyric Acid; Huntington Disease; Hyperkinesis; Male; Neostriatum; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger | 2002 |
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids, Neutral; Animals; Arachidonic Acids; Basal Ganglia; Cannabinoid Receptor Modulators; Capsaicin; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Endocannabinoids; gamma-Aminobutyric Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Palmitates; Piperidines; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington's disease.
Topics: Acetylcholine; Animals; Convulsants; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Male; Mitochondria; Nitro Compounds; Organ Culture Techniques; Potassium Channels; Propionates; Rats; Rats, Sprague-Dawley; Riluzole; Sodium Channels; Succinate Dehydrogenase; Synaptosomes; Tetrodotoxin | 2003 |
Neuronal vulnerability following inhibition of mitochondrial complex II: a possible ionic mechanism for Huntington's disease.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Cell Respiration; Dose-Response Relationship, Drug; Electron Transport Complex II; Enzyme Inhibitors; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Huntington Disease; In Vitro Techniques; Interneurons; Intracellular Fluid; Membrane Potentials; Mice; Mice, Transgenic; Mitochondria; Neostriatum; Nerve Degeneration; Nitro Compounds; Propionates; Rats; Rats, Wistar | 2004 |
Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.
Topics: Animals; Autoradiography; Convulsants; Disease Models, Animal; Dopamine; Dronabinol; Drug Administration Schedule; Drug Interactions; gamma-Aminobutyric Acid; In Situ Hybridization; In Vitro Techniques; Male; Nitro Compounds; Propionates; Psychotropic Drugs; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Striatonigral Degeneration; Succinate Dehydrogenase; Time Factors | 2004 |
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease.
Topics: Animals; Brain Chemistry; Capsaicin; Convulsants; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley | 2005 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Effects of creatine treatment on survival and differentiation of GABA-ergic neurons in cultured striatal tissue.
Topics: Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Corpus Striatum; Creatine; Creatine Kinase; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Administration Schedule; gamma-Aminobutyric Acid; Glucose; Isoenzymes; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Nitro Compounds; Phosphatidylinositol 3-Kinases; Propionates; Rats; Rats, Wistar; Stem Cells; Tissue Distribution | 2005 |
Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype.
Topics: Animals; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Huntington Disease; Male; Motor Activity; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Phenotype; Propionates; Rats; Rats, Wistar; Reflex, Startle; Taurine | 2005 |
Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Creatine; Creatine Kinase; Energy Metabolism; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Mitogen-Activated Protein Kinase 1; Neurons; Nitro Compounds; Pregnancy; Propionates; Rats; Spinal Cord; Stem Cells; Tetrazolium Salts; Thiazoles; Tubulin | 2007 |
Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors.
Topics: Adenosine A2 Receptor Agonists; Animals; Arachidonic Acids; Atrophy; Brain Chemistry; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoids; Chromatography, High Pressure Liquid; Convulsants; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; In Situ Hybridization; Male; Neostriatum; Nitro Compounds; Phosphopyruvate Hydratase; Propionates; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; TRPV Cation Channels | 2007 |
Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.
Topics: alpha-Methyltyrosine; Animals; Apoptosis; Astrocytes; Cell Respiration; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Microglia; Mitochondria; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neurons; Nitro Compounds; Nomifensine; Oxygen Consumption; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Reserpine; Selegiline; Succinate Dehydrogenase; Superoxides; Synaptosomes; Tyrosine 3-Monooxygenase; Up-Regulation | 2008 |
3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Reflex; Spinal Cord; Strychnine; Synaptic Transmission | 2008 |
Metabonomic characterization of the 3-nitropropionic acid rat model of Huntington's disease.
Topics: Animals; Behavior, Animal; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Choline; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Huntington Disease; Lactic Acid; Male; Metabolomics; Nitro Compounds; Nuclear Magnetic Resonance, Biomolecular; Phosphorylcholine; Propionates; Rats; Rats, Sprague-Dawley; Succinic Acid; Taurine | 2009 |
Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity.
Topics: Amines; Animals; Body Weight; Brain; Catalase; Cyclohexanecarboxylic Acids; GABAergic Neurons; Gabapentin; gamma-Aminobutyric Acid; Huntington Disease; Lamotrigine; Lipid Peroxidation; Locomotion; Male; Mitochondria; Neuroprotective Agents; Neurotoxins; Nitrites; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Rotarod Performance Test; Superoxide Dismutase; Triazines; Tumor Necrosis Factor-alpha | 2012 |