3-nitropropionic acid has been researched along with calpain in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (77.78) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dewar, D; Hunter, AJ; McCracken, E | 1 |
| Cattaneo, E; De Micheli, A; Goffredo, D; Matteoli, M; Rigamonti, D; Tartari, M; Verderio, C; Zuccato, C | 1 |
| Bizat, N; Boyer, F; Brouillet, E; Créminon, C; Escartin, C; Hantraye, P; Hermel, JM; Jacquard, C; Kajewski, S; Ouary, S | 1 |
| Bondada, V; Geddes, JW; Pang, Z; Sengoku, T; Siman, R | 1 |
| Bizat, N; Brouillet, E; Créminon, C; Escartin, C; Hantraye, P; Hermel, JM; Humbert, S; Jacquard, C; Krajewski, S; Saudou, F | 1 |
| Beal, MF; Bizat, N; Brouillet, E; Joh, TH; Kiaei, M; Mischak, RP; Sugama, S; Yang, L | 1 |
| Bantubungi, K; Blum, D; Brotchi, J; Brouillet, E; Chtarto, A; Déglon, N; Galas, MC; Greco, A; Jacquard, C; Levivier, M; Minghetti, L; Pintor, A; Popoli, P; Schiffmann, SN; Tai, K; Tenenbaum, L | 1 |
| Bizat, N; Blum, D; Boyer, F; Brouillet, E; Galas, MC; Hantraye, P; Hermel, JM; Jacquard, C; Schiffmann, SN | 1 |
| Bizat, N; Bonvento, G; Brouillet, E; Cancela, JM; Cosker, F; Escartin, C; Hantraye, P; Jacquard, C; Trioulier, Y | 1 |
| Chu, K; Jung, KH; Kang, L; Kim, M; Ko, SY; Lee, ST; Park, JE | 1 |
| Camins, A; Canudas, AM; Crespo-Biel, N; Pallàs, M; Pelegrí, C; Vilaplana, J | 1 |
| Akashiba, H; Ikegaya, Y; Matsuki, N; Nishiyama, N | 1 |
| Camins, A; Canudas, AM; Crespo-Biel, N; Pallàs, M | 1 |
| Gañan, CM; Garcia-Martinez, V; Gutierrez-Merino, C; Lagoa, R; Lopez-Sanchez, C; Samhan-Arias, AK | 1 |
| Camins, A; Canudas, AM; Crespo-Biel, N; Gutiérrez-Cuesta, J; Melchiorri, D; Nicoletti, F; Pallàs, M | 1 |
| Aguirre, N; Barros-Miñones, L; Cuadrado-Tejedor, M; García-Osta, A; Hervias, I; Jordan, J; Puerta, E; Ricobaraza, A | 1 |
| Aguirre, N; Chowdhury, D; Marco, S; Martínez-Turrillas, R; Pérez-Otaño, I; Puerta, E; Watanabe, M | 1 |
| Abolhassani, N; Nakabeppu, Y; Nomaru, H; Oka, S; Sakumi, K; Sheng, Z; Tsuchimoto, D; Yamada, H | 1 |
18 other study(ies) available for 3-nitropropionic acid and calpain
| Article | Year |
|---|---|
White matter damage following systemic injection of the mitochondrial inhibitor 3-nitropropionic acid in rat.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Brain Diseases; Calpain; Cytoskeleton; Free Radicals; Immunohistochemistry; Male; Mitochondria; Neuroglia; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons.
Topics: Animals; Blotting, Western; Brain; Calcimycin; Calcium; Calpain; Cell-Free System; Cells, Cultured; Densitometry; Glutamic Acid; Huntingtin Protein; Ionophores; Nerve Tissue Proteins; Neurons; Nitro Compounds; Nuclear Proteins; Propionates; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease.
Topics: Acute Disease; Animals; Calpain; Caspases; Cell Death; Chronic Disease; Corpus Striatum; Disease Models, Animal; DNA Fragmentation; Drug Administration Routes; Electron Transport Complex II; Enzyme Inhibitors; Huntingtin Protein; Huntington Disease; Male; Mitochondria; Multienzyme Complexes; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Oxidoreductases; Propionates; Rats; Rats, Inbred Lew; Succinate Dehydrogenase | 2003 |
Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Immunoblotting; Immunohistochemistry; Necrosis; Neurons; Neurotoxins; Nitro Compounds; Oligopeptides; Propionates; Rats; Spectrin; Time Factors | 2003 |
In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Brain; Calpain; Caspase 3; Caspase 9; Caspases; Cell-Free System; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Inhibitory Concentration 50; Male; Models, Biological; Molecular Sequence Data; Neurodegenerative Diseases; Neurons; Nitro Compounds; Propionates; Protein Binding; Protein Structure, Tertiary; Rats; Rats, Inbred Lew; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors | 2003 |
A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Chloromethyl Ketones; Animals; BH3 Interacting Domain Death Agonist Protein; Brain; Calpain; Carrier Proteins; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Corpus Striatum; Dopamine Agents; Enzyme Inhibitors; Male; Malonates; Mesencephalon; Mice; Neurotoxins; Nitro Compounds; Propionates; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 2004 |
Minocycline in phenotypic models of Huntington's disease.
Topics: Animals; Calpain; Caspases; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Minocycline; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Phenotype; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Wistar; Staurosporine | 2005 |
Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain.
Topics: Animals; Calpain; Carrier Proteins; Cell Death; Huntington Disease; Immunohistochemistry; Injections, Intraventricular; Male; Microfilament Proteins; Neostriatum; Nerve Degeneration; Neuroprotective Agents; Nitro Compounds; Oligopeptides; Propionates; Protease Inhibitors; Rats; Rats, Inbred Lew; Rats, Wistar | 2005 |
Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation.
Topics: Animals; Calcium Signaling; Calpain; Cells, Cultured; Corpus Striatum; Male; Mitochondria; Neurons; Nitro Compounds; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Receptors, N-Methyl-D-Aspartate | 2006 |
Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease.
Topics: Animals; Apoptosis Regulatory Proteins; Calpain; Cell Death; Corpus Striatum; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; Huntingtin Protein; Huntington Disease; Male; Memantine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Nuclear Proteins; Peptide Fragments; Propionates; Rats; Rats, Sprague-Dawley | 2006 |
3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum.
Topics: Analysis of Variance; Animals; Calpain; Convulsants; Corpus Striatum; Cyclin-Dependent Kinase 5; Enzyme Activation; Male; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors | 2007 |
Differential involvement of cell cycle reactivation between striatal and cortical neurons in cell death induced by 3-nitropropionic acid.
Topics: Animals; Calcium Signaling; Calpain; Cell Death; Cerebral Cortex; Convulsants; Corpus Striatum; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; G1 Phase; Huntington Disease; Nitro Compounds; Organ Specificity; Phosphorylation; Propionates; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retinoblastoma Protein; RNA, Small Interfering; Succinate Dehydrogenase | 2008 |
Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro.
Topics: Animals; Calcium; Calpain; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Gene Expression Regulation; Hippocampus; Huntington Disease; Lithium Chloride; Male; Mice; Neurons; Neuroprotective Agents; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Signal Transduction; Succinate Dehydrogenase | 2009 |
Kaempferol protects against rat striatal degeneration induced by 3-nitropropionic acid.
Topics: Animals; Calpain; Caspases; Convulsants; Corpus Striatum; Creatine Kinase; Disease Models, Animal; Huntington Disease; Kaempferols; Male; Nerve Degeneration; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species | 2009 |
Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model.
Topics: Amino Acid Chloromethyl Ketones; Aminophenols; Animals; Calpain; Caspases; Cell Survival; Cells, Cultured; Convulsants; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Maleimides; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Nitro Compounds; Propionates; Purines; Rats; Roscovitine; Signal Transduction; Time Factors | 2010 |
Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Calpain; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Motor Activity; Neurons; Neurotoxicity Syndromes; Neurotoxins; Nitro Compounds; Phosphodiesterase Inhibitors; Piperazines; Propionates; Purines; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Sildenafil Citrate; Succinate Dehydrogenase; Sulfones | 2010 |
The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation.
Topics: Animals; Blotting, Western; Calpain; Convulsants; Corpus Striatum; Enzyme Activation; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Transgenic; Nitro Compounds; Propionates; Protein Subunits; Receptors, N-Methyl-D-Aspartate | 2012 |
8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.
Topics: Animals; Apoptosis Inducing Factor; Benzamides; Calpain; Cell Nucleus; Corpus Striatum; Dipeptides; DNA Breaks, Single-Stranded; DNA Glycosylases; DNA Repair; DNA, Mitochondrial; Guanine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Mitochondria; Motor Activity; Neurodegenerative Diseases; Nitro Compounds; Oxidative Stress; Phosphoric Monoester Hydrolases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Propionates | 2012 |