3-nitropropionic acid and alpha-synuclein

3-nitropropionic acid has been researched along with alpha-synuclein in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haass, C; Kahle, PJ; Neumann, M; Poewe, W; Reindl, M; Stefanova, N; Wenning, GK1
Abeliovich, A; Beal, MF; Cleren, C; Ferrante, RJ; Gardian, G; Klivenyi, P; Kowall, NW; Siwek, D; Starkov, A; Yang, L1
Poewe, W; Stefanova, N; Wenning, GK1
Adame, A; Inglis, C; Lee, PH; Mante, M; Masliah, E; Rockenstein, E; Stefanova, N; Ubhi, K; Wenning, GK1
Beal, MF; Calingasan, NY; Cormier, K; Ferrante, RJ; Smith, K; Wille, EJ; Yang, L1
Adame, A; Inglis, C; Mante, M; Masliah, E; Patrick, C; Rockenstein, E; Ubhi, K1
Köllensperger, M; Krismer, F; Pallua, A; Poewe, W; Stefanova, N; Wenning, GK1
Alvarez-Fischer, D; Bouillot, C; Castagner, F; Faigle, W; Fuchs, J; Hartmann, A; Joshi, RL; Lombès, A; Massiani-Beaudoin, O; Moya, KL; Oertel, WH; Prochiantz, A; Stettler, O1
Georgievska, B; Kaindlstorfer, C; Kugler, AR; Mather, RJ; Poewe, W; Sommer, P; Stefanova, N; Wenning, GK1
Goldbaum, O; Pukaß, K; Richter-Landsberg, C1

Other Studies

10 other study(ies) available for 3-nitropropionic acid and alpha-synuclein

ArticleYear
Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy.
    The American journal of pathology, 2005, Volume: 166, Issue:3

    Topics: alpha-Synuclein; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Disease Models, Animal; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Transgenic; Microglia; Movement; Movement Disorders; Multiple System Atrophy; Nerve Tissue Proteins; Neurons; Nitro Compounds; Oligodendroglia; Oxidative Stress; Propionates; Synucleins; Time Factors

2005
Mice lacking alpha-synuclein are resistant to mitochondrial toxins.
    Neurobiology of disease, 2006, Volume: 21, Issue:3

    Topics: alpha-Synuclein; Animals; Malonates; Mice; Mice, Mutant Strains; Mitochondria; Neurons; Neurotoxins; Nitro Compounds; Parkinsonian Disorders; Propionates

2006
Rasagiline is neuroprotective in a transgenic model of multiple system atrophy.
    Experimental neurology, 2008, Volume: 210, Issue:2

    Topics: alpha-Synuclein; Analysis of Variance; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Indans; Mice; Mice, Transgenic; Motor Activity; Multiple System Atrophy; Myelin Proteolipid Protein; Neurons; Neuroprotective Agents; Nitro Compounds; Propionates; Psychomotor Performance; Tyrosine 3-Monooxygenase

2008
Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy.
    Journal of neuroscience research, 2009, Volume: 87, Issue:12

    Topics: alpha-Synuclein; Animals; Brain; Convulsants; Disease Models, Animal; Mice; Mice, Transgenic; Mitochondria; Multiple System Atrophy; Myelin Basic Protein; Nerve Degeneration; Nitrates; Nitro Compounds; Oxidative Stress; Promoter Regions, Genetic; Propionates

2009
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 8-Hydroxy-2'-Deoxyguanosine; alpha-Synuclein; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Creatine; Deoxyguanosine; Disease Models, Animal; Dopamine; Drug Therapy, Combination; Glutathione; Glutathione Disulfide; Huntington Disease; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitro Compounds; Parkinson Disease; Propionates; Rats; Rats, Inbred Lew; Tyrosine 3-Monooxygenase; Ubiquinone

2009
Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy.
    Neuroreport, 2010, Apr-21, Volume: 21, Issue:6

    Topics: alpha-Synuclein; Animals; Brain; Disease Models, Animal; Mice; Mice, Knockout; Mice, Transgenic; Multiple System Atrophy; Neurons; Nitro Compounds; Oxidative Stress; Propionates

2010
Erythropoietin is neuroprotective in a transgenic mouse model of multiple system atrophy.
    Movement disorders : official journal of the Movement Disorder Society, 2011, Feb-15, Volume: 26, Issue:3

    Topics: alpha-Synuclein; Animals; Cell Death; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Administration Schedule; Erythropoietin; Exploratory Behavior; Humans; Mice; Mice, Transgenic; Motor Activity; Multiple System Atrophy; Myelin Proteolipid Protein; Nitro Compounds; Propionates; Substantia Nigra; Tyrosine 3-Monooxygenase

2011
Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.
    Nature neuroscience, 2011, Sep-04, Volume: 14, Issue:10

    Topics: alpha-Synuclein; Animals; Cell Count; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electron Transport Chain Complex Proteins; Embryo, Mammalian; Homeodomain Proteins; In Vitro Techniques; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADH Dehydrogenase; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitro Compounds; Oxidopamine; Propionates; RNA, Small Interfering; Rotenone; Stereotyped Behavior; Tyrosine 3-Monooxygenase

2011
Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications.
    Neurotoxicity research, 2015, Volume: 28, Issue:3

    Topics: alpha-Synuclein; Animals; Brain; Disease Models, Animal; Enzyme Inhibitors; Humans; Male; Mice, Transgenic; Microglia; Motor Activity; Multiple System Atrophy; Myelin Proteolipid Protein; Neurons; Neuroprotective Agents; Nitro Compounds; Peroxidase; Propionates; Pyrimidinones; Pyrroles; Severity of Illness Index; Treatment Outcome

2015
Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells.
    Journal of neurochemistry, 2015, Volume: 135, Issue:1

    Topics: alpha-Synuclein; Animals; Autophagy; Cells, Cultured; Cytoplasm; Mitochondria; Multiple System Atrophy; Nerve Tissue Proteins; Nitro Compounds; Oligodendroglia; Oxidative Stress; Propionates; Rats

2015