3-n-methylspiperone has been researched along with sulpiride in 5 studies
| Studies (3-n-methylspiperone) | Trials (3-n-methylspiperone) | Recent Studies (post-2010) (3-n-methylspiperone) | Studies (sulpiride) | Trials (sulpiride) | Recent Studies (post-2010) (sulpiride) |
|---|---|---|---|---|---|
| 155 | 6 | 7 | 4,152 | 427 | 635 |
| Protein | Taxonomy | 3-n-methylspiperone (IC50) | sulpiride (IC50) |
|---|---|---|---|
| Carbonic anhydrase 1 | Homo sapiens (human) | 1.2 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.04 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.019 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0858 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.2651 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2215 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.62 | |
| D(2) dopamine receptor | Canis lupus familiaris (dog) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG | 1 |
| Nowak, JZ; Schorderet, M | 1 |
| Ballesteros, JA; Chen, J; Fu, D; Javitch, JA; Weinstein, H | 1 |
| Chen, J; Fu, D; Javitch, JA | 1 |
| Ballesteros, JA; Chen, J; Javitch, JA; Weinstein, H | 1 |
1 review(s) available for 3-n-methylspiperone and sulpiride
| Article | Year |
|---|---|
Retinal dopamine D1 and D2 receptors: characterization by binding or pharmacological studies and physiological functions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Arylamine N-Acetyltransferase; Benzazepines; Colforsin; Cyclic AMP; Dopamine; Ergolines; Light; Quinpirole; Receptors, Dopamine; Retina; Second Messenger Systems; Species Specificity; Spiperone; Sulpiride; Vertebrates | 1990 |
4 other study(ies) available for 3-n-methylspiperone and sulpiride
| Article | Year |
|---|---|
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.
Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship | 1988 |
Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Dopamine Antagonists; Ethyl Methanesulfonate; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Dopamine D2; Signal Transduction; Spiperone; Sulfhydryl Reagents; Sulpiride | 1996 |
Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Resistance; Ethyl Methanesulfonate; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Dopamine D2; Spiperone; Sulpiride; Transfection | 1995 |
A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Ethyl Methanesulfonate; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Dopamine D2; Spiperone; Sulpiride | 1998 |