Page last updated: 2024-09-03

3-n-methylspiperone and risperidone

3-n-methylspiperone has been researched along with risperidone in 1 studies

Compound Research Comparison

Studies
(3-n-methylspiperone)
Trials
(3-n-methylspiperone)
Recent Studies (post-2010)
(3-n-methylspiperone)
Studies
(risperidone)
Trials
(risperidone)
Recent Studies (post-2010) (risperidone)
155676,9241,5052,477

Protein Interaction Comparison

ProteinTaxonomy3-n-methylspiperone (IC50)risperidone (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.015
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0027
Alpha-2A adrenergic receptorHomo sapiens (human)0.0097
Cytochrome P450 2D6Homo sapiens (human)5.2734
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)4.1901
D(2) dopamine receptorHomo sapiens (human)0.0167
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0991
Alpha-2B adrenergic receptorHomo sapiens (human)0.026
Alpha-2C adrenergic receptorHomo sapiens (human)0.0096
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.799
D(1A) dopamine receptorHomo sapiens (human)0.479
Histamine H2 receptorHomo sapiens (human)1.483
Alpha-1D adrenergic receptorHomo sapiens (human)0.01
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0016
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0057
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.799
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0027
5-hydroxytryptamine receptor 2C Mus musculus (house mouse)0.0015
Alpha-1A adrenergic receptorHomo sapiens (human)0.0105
5-hydroxytryptamine receptor 2AMus musculus (house mouse)0.0015
Histamine H1 receptorHomo sapiens (human)0.4515
D(3) dopamine receptorHomo sapiens (human)0.024
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.023
D(2) dopamine receptorMus musculus (house mouse)0.023
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0154
5-hydroxytryptamine receptor 2BMus musculus (house mouse)0.0015
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.6303
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.43
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)4.1901
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eriksson, B; Farde, L; Halldin, C; Nyberg, S; Oxenstierna, G1

Trials

1 trial(s) available for 3-n-methylspiperone and risperidone

ArticleYear
Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients.
    The American journal of psychiatry, 1999, Volume: 156, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Psychiatric Status Rating Scales; Raclopride; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Schizophrenia; Schizophrenic Psychology; Spiperone; Tomography, Emission-Computed; Treatment Outcome

1999