3-n-methylspiperone has been researched along with cocaine in 6 studies
| Studies (3-n-methylspiperone) | Trials (3-n-methylspiperone) | Recent Studies (post-2010) (3-n-methylspiperone) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 155 | 6 | 7 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | 3-n-methylspiperone (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alpert, R; Bendriem, B; Christman, D; Dewey, SL; Fowler, JS; Logan, J; Schlyer, D; Shiue, CY; Volkow, ND; Wolf, AP | 1 |
| Dewey, SL; Fowler, JS; Hitzemann, R; Logan, J; Schlyer, DJ; Volkow, ND; Wang, GJ; Wolf, AP | 1 |
| Gatley, SJ | 1 |
| Futatsubashi, M; Kakiuchi, T; Kreek, MJ; Kreuter, J; Maggos, CE; Nishiyama, S; Tsukada, H; Unterwald, EM | 1 |
| Ho, A; Kakiuchi, T; Kreek, MJ; Kreuter, J; Maggos, CE; Myers, JE; Nishiyama, S; Schlussman, SD; Tsukada, H; Unterwald, EM | 1 |
| Gee, A; Hosoi, R; Inoue, O; Kobayashi, K | 1 |
6 other study(ies) available for 3-n-methylspiperone and cocaine
| Article | Year |
|---|---|
Effects of chronic cocaine abuse on postsynaptic dopamine receptors.
Topics: Adult; Basal Ganglia; Cocaine; Corpus Striatum; Down-Regulation; Fluorine Radioisotopes; Humans; Receptors, Dopamine; Spiperone; Substance-Related Disorders; Tomography, Emission-Computed; Up-Regulation | 1990 |
Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers.
Topics: Adult; Brain; Cocaine; Deoxyglucose; Dopamine Agents; Fluorodeoxyglucose F18; Frontal Lobe; Glucose; Humans; Male; Receptors, Dopamine D2; Reference Values; Spiperone; Substance-Related Disorders; Tomography, Emission-Computed | 1993 |
Estimation of upper limits on human radiation absorbed doses from carbon-11-labeled compounds.
Topics: Animals; Benztropine; Carbon Radioisotopes; Cocaine; Deoxyglucose; Dogs; Humans; Mice; Models, Biological; Papio; Putrescine; Radiation Dosage; Selegiline; Spiperone; Tissue Distribution | 1993 |
Effects of binge pattern cocaine administration on dopamine D1 and D2 receptors in the rat brain: an in vivo study using positron emission tomography.
Topics: Animals; Benzazepines; Brain; Cocaine; Dopamine Agonists; Dopamine Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tomography, Emission-Computed | 1996 |
Sustained withdrawal allows normalization of in vivo [11C]N-methylspiperone dopamine D2 receptor binding after chronic binge cocaine: a positron emission tomography study in rats.
Topics: Analysis of Variance; Animals; Benzazepines; Brain; Carbon Radioisotopes; Cocaine; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Spiperone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Tomography, Emission-Computed | 1998 |
Opposing effects of clomipramine on [125I]RTI-55 and [3H]N-methylspiperone binding in mouse striatum: important role of other factors than endogenous dopamine?
Topics: Animals; Brain; Carrier Proteins; Clomipramine; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Organ Specificity; Radioligand Assay; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spiperone; Tritium | 1998 |