3-n-butylphthalide has been researched along with aspirin in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Hu, GY; Wang, Y; Wang, ZH; Yang, H | 1 |
| Fu, R; Lai, Y; Li, Y; Peng, S; Wang, X; Yu, W; Zhang, Y | 1 |
| Ji, H; Lai, Y; Li, T; Ling, J; Liu, J; Peng, S; Tian, J; Wang, X; Wu, J; Zhang, Y | 1 |
| Hua, K; Huang, Z; Ji, H; Sheng, X; Wang, X; Xu, J; Yang, C; Zhang, Y | 1 |
| Cao, Z; Cong, S; Deng, Y; Liu, Z; Song, Q; Tan, Z; Yu, G | 1 |
| Chong, ZZ; Feng, YP | 1 |
| Huang, RX; Li, CX; Liao, SJ; Lin, JW; Liu, CL; Shi, XG; Xie, LC; Zeng, JS | 1 |
| Gao, YL; Guo, JJ; Wang, M; Wang, ZY; Yu, XF | 1 |
| Lv, J; Xie, Z; Zhao, D; Zhao, G | 1 |
| Du, Y; Li, L; Li, X; Lv, Y; Tan, J; Zhai, X | 1 |
1 trial(s) available for 3-n-butylphthalide and aspirin
| Article | Year |
|---|---|
Efficacy and safety of butylphthalide in secondary prevention of stroke: study protocol for a multicenter, real world trial based on Internet.
Topics: Aspirin; Benzofurans; Clopidogrel; Double-Blind Method; Humans; Internet; Ischemic Stroke; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Secondary Prevention; Treatment Outcome | 2022 |
9 other study(ies) available for 3-n-butylphthalide and aspirin
| Article | Year |
|---|---|
Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone.
Topics: Drug Evaluation, Preclinical; Furans; Platelet Aggregation Inhibitors | 2007 |
Synthesis and evaluation of nitric oxide-releasing derivatives of 3-n-butylphthalide as anti-platelet agents.
Topics: Adenosine Diphosphate; Animals; Benzoates; Benzofurans; Blood Platelets; Caffeic Acids; Nitrates; Nitric Oxide; Platelet Aggregation Inhibitors; Rabbits | 2011 |
Discovery of a potential anti-ischemic stroke agent: 3-pentylbenzo[c]thiophen-1(3H)-one.
Topics: Animals; Antioxidants; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Fibrinolytic Agents; Free Radical Scavengers; Male; Neuroprotective Agents; PC12 Cells; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stereoisomerism; Stroke; Structure-Activity Relationship; Thiophenes | 2012 |
Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agents.
Topics: Animals; Antipyrine; Benzofurans; Cell Line; Drug Design; Edaravone; Free Radical Scavengers; Humans; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Stroke | 2015 |
Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Benzylidene Compounds; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Copper; Dose-Response Relationship, Drug; Electrophorus; Female; Humans; Male; Mannich Bases; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Protein Aggregates; Rats; Structure-Activity Relationship | 2021 |
Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Benzofurans; Brain; Ischemic Attack, Transient; Neuroprotective Agents; Rats; Reperfusion Injury; Thromboxane B2 | 1997 |
dl-3n-butylphthalide prevents stroke via improvement of cerebral microvessels in RHRSP.
Topics: Animals; Aspirin; Benzofurans; Brain; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Cold Temperature; Dextrans; Disease Models, Animal; Fluorescein-5-isothiocyanate; Hypertension, Renal; Male; Microcirculation; Molecular Structure; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Stroke; Treatment Outcome | 2007 |
Acute bilateral cerebral infarction in the presence of neuromyelitis optica spectrum disorder: A case report.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Anticholesteremic Agents; Aphasia, Broca; Aspirin; Atorvastatin; Benzofurans; Cerebral Infarction; Female; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Neuromyelitis Optica; Neuroprotective Agents; Plasmapheresis; Platelet Aggregation Inhibitors; Treatment Outcome | 2020 |
A pharmacokinetics interaction study of antiplatelet agents aspirin and clopidogrel combined with dl-3-n-butylphthalide in rats by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clopidogrel; Platelet Aggregation Inhibitors; Rats; Salicylic Acid; Tandem Mass Spectrometry | 2023 |