3-n-butyl-4,5-dihydrophthalide has been researched along with ligustilide in 18 studies
| Studies (3-n-butyl-4,5-dihydrophthalide) | Trials (3-n-butyl-4,5-dihydrophthalide) | Recent Studies (post-2010) (3-n-butyl-4,5-dihydrophthalide) | Studies (ligustilide) | Trials (ligustilide) | Recent Studies (post-2010) (ligustilide) |
|---|---|---|---|---|---|
| 45 | 0 | 23 | 223 | 0 | 150 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, M; Ozaki, Y; Sekita, S | 1 |
| Kimura, I; Kimura, M; Kobayashi, S; Mimura, Y; Naitoh, T | 1 |
| Chen, BM; He, YK; Hu, QN; Li, BY; Liang, YZ; Wang, YL | 1 |
| Cao, J; Ding, M; Kou, H; Wang, Z; Yang, X | 1 |
| Chan, SS; Cheng, TY; Lin, G | 1 |
| Liang, XM; Xiao, YS; Xu, Q; Xue, XY; Yang, F; Zhang, FF | 1 |
| Chen, C; Du, JR; Tang, J; Wang, CY; Yang, W; Yu, Y | 1 |
| Lau, AS; Law, AH; Li, JC; Or, TC; Yang, CL | 1 |
| Ding, W; Duan, J; Liu, P; Qian, D; Shang, E; Tang, Y; Wu, J | 1 |
| Li, YB; Lou, JS; Su, LN; Wang, YM | 1 |
| Fan, QJ; Kong, FL; Liu, JL; Tan, J; Yang, SM; Yuan, JC; Zheng, SL; Zhou, J | 1 |
| Cai, H; Pei, K; Qiao, FX; Song, XQ; Tu, PF | 1 |
| Chen, Y; Huang, ZF; Liu, YH; Yang, Y; Yi, JH | 1 |
| Hu, PY; Liu, D; Tang, Y; Wu, Q; Yang, M; Zheng, Q | 1 |
| Bai, G; Deng, YF; Hu, XY; Jiang, M; Lei, W; Ni, JN | 1 |
| Hu, N; Jiang, W; Liu, L; Shi, L; Wang, Q; Yan, T; Yang, P; Zhang, S; Zhang, W | 1 |
| An, C; Dong, Y; Li, M; Li, X; Wang, X; Xiang, F; Yao, Y | 1 |
| Chen, J; Jin, L; Shi, T; Xu, X; Zhu, T | 1 |
18 other study(ies) available for 3-n-butyl-4,5-dihydrophthalide and ligustilide
| Article | Year |
|---|---|
[Centrally acting muscle relaxant effect of phthalides (ligustilide, cnidilide and senkyunolide) obtained from Cnidium officinale Makino].
Topics: 4-Butyrolactone; Animals; Benzofurans; Drugs, Chinese Herbal; Furans; Male; Mephenesin; Muscle Relaxants, Central; Rats; Rats, Inbred Strains | 1989 |
Chemical structure-activity of cnidium rhizome-derived phthalides for the competence inhibition of proliferation in primary cultures of mouse aorta smooth muscle cells.
Topics: 4-Butyrolactone; Analysis of Variance; Animals; Aorta, Thoracic; Benzofurans; Cell Division; Cells, Cultured; Drugs, Chinese Herbal; Male; Mice; Muscle, Smooth, Vascular; Phthalic Anhydrides; Structure-Activity Relationship | 1993 |
LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui.
Topics: 4-Butyrolactone; Absorption; Administration, Oral; Aldehydes; alpha-Linolenic Acid; Angelica sinensis; Animals; Benzofurans; Diynes; Drugs, Chinese Herbal; Fatty Alcohols; Linoleic Acid; Mass Spectrometry; Phthalic Anhydrides; Plant Extracts; Rabbits | 2005 |
[Determination of lactone components in chuanxiong by reversed-phase high performance liquid chromatography].
Topics: 4-Butyrolactone; Benzofurans; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Ligusticum; Reproducibility of Results | 2005 |
Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta.
Topics: 4-Butyrolactone; Animals; Aorta, Thoracic; Benzofurans; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium, Vascular; Ligusticum; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
[High performance liquid chromatography-mass spectrometry analysis of radix Angelica sciensis].
Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Molecular Structure; Phthalic Anhydrides; Plant Roots; Plants, Medicinal; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2006 |
[Pharmacological activities of Z-ligustilide and metabolites in rats].
Topics: 4-Butyrolactone; Animals; Benzofurans; Biotransformation; Hydrogen Peroxide; Male; Microsomes, Liver; Oxidative Stress; PC12 Cells; Protective Agents; Rats; Rats, Sprague-Dawley | 2009 |
Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Biological Assay; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Humans; Ligusticum; Lipopolysaccharides; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Tumor Necrosis Factor-alpha | 2011 |
[Influence of different solutions on extracting of active components in Danggui Chishao drug pair].
Topics: 4-Butyrolactone; Benzoates; Benzofurans; Bridged-Ring Compounds; Chromatography, Liquid; Drugs, Chinese Herbal; Gallic Acid; Glucosides; Hydroxybenzoates; Mass Spectrometry; Monoterpenes; Phthalic Acids; Solvents; Vanillic Acid | 2012 |
[Study on the constituents of essential oil of Shunaoxin dropping pills by GC-MS].
Topics: 4-Butyrolactone; Angelica; Apiaceae; Benzofurans; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lactones; Oils, Volatile; Phthalic Anhydrides | 2013 |
[Quantitative determination of 5 active ingredients in different harvest periods of Ligusticum chuanxiong by HPLC].
Topics: 4-Butyrolactone; Acetic Acid; Acetonitriles; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Ligusticum; Methanol; Solvents; Time Factors | 2014 |
[Establishment and application of HPLC-QAMS for quality evaluation of Chuanxiong Rhizoma].
Topics: 4-Butyrolactone; Acetonitriles; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Hydroxybenzoates; Quality Control; Rhizome | 2015 |
[Comparative Study on Volatile Oil Composition of Chuanxiong Rhizoma, Angelicae Sinensis Radix and Ligustici Rhizoma et Radix].
Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ligusticum; Oils, Volatile; Phthalic Anhydrides; Plant Oils; Plant Roots; Rhizome | 2015 |
Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model.
Topics: 4-Butyrolactone; Animals; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Biological Transport; Blood-Brain Barrier; Dogs; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucosides; Humans; In Vitro Techniques; Madin Darby Canine Kidney Cells; Molecular Structure; Monoterpenes | 2016 |
Phthalides, senkyunolide A and ligustilide, show immunomodulatory effect in improving atherosclerosis, through inhibiting AP-1 and NF-κB expression.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Benzofurans; HEK293 Cells; Humans; Immunologic Factors; Inflammation Mediators; Lipids; Male; Mice, Inbred C57BL; NF-kappa B; Proto-Oncogene Proteins c-akt; Transcription Factor AP-1; Tumor Necrosis Factor Receptor Superfamily, Member 9 | 2019 |
Simultaneous quantification of ligustilide, dl-3-n-butylphthalide and senkyunolide A in rat plasma by GC-MS and its application to comparative pharmacokinetic studies of Rhizoma Chuanxiong extract alone and Baizhi Chuanxiong Decoction.
Topics: 4-Butyrolactone; Administration, Oral; Animals; Benzofurans; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2019 |
Simultaneous determination of 20 bioactive components in Chuanxiong Rhizoma from different production origins in Sichuan province by ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry combined with multivariate s
Topics: 4-Butyrolactone; Benzofurans; China; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Geography; Limit of Detection; Linear Models; Multivariate Analysis; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |
Quality suitability regionalization analysis of Angelica sinensis in Gansu, China.
Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; China; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Plant Extracts | 2020 |