Page last updated: 2024-09-03

3-n-(2-fluoroethyl)spiperone and olanzapine

3-n-(2-fluoroethyl)spiperone has been researched along with olanzapine in 1 studies

Compound Research Comparison

Studies
(3-n-(2-fluoroethyl)spiperone)
Trials
(3-n-(2-fluoroethyl)spiperone)
Recent Studies (post-2010)
(3-n-(2-fluoroethyl)spiperone)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
26216,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomy3-n-(2-fluoroethyl)spiperone (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bravi, D; Cavallaro, R; Colombo, C; Fazio, F; Galli, L; Gobbo, C; Lucignani, G; Messa, C; Moresco, RM; Rizzo, G; Smeraldi, E; VelonĂ , I1

Trials

1 trial(s) available for 3-n-(2-fluoroethyl)spiperone and olanzapine

ArticleYear
Cerebral D2 and 5-HT2 receptor occupancy in Schizophrenic patients treated with olanzapine or clozapine.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Double-Blind Method; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Olanzapine; Positron-Emission Tomography; Prospective Studies; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spiperone

2004