Page last updated: 2024-08-25

3-methylxanthine and 1-methylxanthine

3-methylxanthine has been researched along with 1-methylxanthine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's9 (56.25)18.2507
2000's3 (18.75)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Hasegawa, T; Iwasaki, N; Kakiuchi, M; Kato, H; Konno, K; Miyamoto, K; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y1
Daly, JW; Padgett, WL; Shamim, MT; Ukena, D1
Daly, JW; Manning, M; Müller, CE; Shi, D1
Cameron, IL; Lyles, MB; Rawls, HR1
Karnes, HT; Sarkar, MA1
Guzelian, PS; Hunt, C; Karnes, HT; Polk, RE; Sarkar, M1
Birkett, DJ; Gregor, D; McManus, ME; Miners, JO; Stupans, I1
Chen, J; Follath, F; Freiburghaus, AU; Ha, HR1
Brøsen, K; Nielsen, KK; Rasmussen, BB1
Iga, T; Kawakami, J; Sawada, Y; Toyama, E; Yamamoto, K1
Norman, A; Rodopoulos, N1
Cao, W; Chen, G; Ling, SS; Zhuo, HT1
Kim, JQ; Park, HD; Park, KU; Song, J; Yoon, Y1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL1
Chae, JW; Kim, DH; Kim, Ej; Kwon, KI; Lee, BY1
Li, X; Ma, C; Ren, X; Xia, T; Zhou, B1

Other Studies

16 other study(ies) available for 3-methylxanthine and 1-methylxanthine

ArticleYear
Effects of alkyl substitutions of xanthine skeleton on bronchodilation.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Animals; Bronchodilator Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Organ Specificity; Receptors, Purinergic; Structure-Activity Relationship; Trachea; Xanthines

1992
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines

1989
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
    Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22

    Topics: Animals; Brain; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline; Xanthines

1993
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines

2001
High performance liquid chromatographic determination of theophylline metabolites in human liver microsomes.
    Biomedical chromatography : BMC, 1991, Volume: 5, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Microchemistry; Microsomes, Liver; Quality Control; Uric Acid; Xanthines

1991
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4

    Topics: Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Hydroxylation; Microsomes, Liver; Norfloxacin; Theophylline; Uric Acid; Xanthines

1990
Theophylline metabolism by human, rabbit and rat liver microsomes and by purified forms of cytochrome P450.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:6

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Theophylline; Uric Acid; Xanthines

1988
Metabolism of theophylline by cDNA-expressed human cytochromes P-450.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:3

    Topics: Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Induction; Epoxide Hydrolases; Humans; Hydroxylation; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Regression Analysis; Smoking; Theophylline; Tumor Cells, Cultured; Uric Acid; Xanthines

1995
Determination of theophylline metabolites in human liver microsomes by high-performance liquid chromatography.
    Analytical biochemistry, 1994, Volume: 222, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Microsomes, Liver; Reproducibility of Results; Spectrophotometry, Ultraviolet; Uric Acid; Xanthines

1994
Neurotoxic convulsions induced by theophylline and its metabolites in mice.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Infusions, Intravenous; Injections, Intraventricular; Male; Mice; Neurotoxins; Seizures; Theophylline; Uric Acid; Xanthines

1996
Elimination of theophylline metabolites in healthy adults.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:3

    Topics: Administration, Oral; Adult; Female; Humans; Male; Middle Aged; Theophylline; Time Factors; Uric Acid; Xanthines

1997
Pharmacokinetics of theophylline metabolites in 8 Chinese patients.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Adult; Aminophylline; Asthma; Bronchodilator Agents; Circadian Rhythm; Humans; Middle Aged; Theophylline; Uric Acid; Xanthines

1998
High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
    Clinical chemistry, 2004, Volume: 50, Issue:11

    Topics: Bronchodilator Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Plasma; Theophylline; Uric Acid; Xanthines

2004
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
    Journal of bacteriology, 2009, Volume: 191, Issue:14

    Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2009
Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Mar-15, Volume: 889-890

    Topics: Animals; Chromatography, Liquid; Drug Stability; Least-Squares Analysis; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines

2012
LC-MS/MS-based metabolomic analysis of caffeine-degrading fungus Aspergillus sydowii during tea fermentation.
    Journal of food science, 2020, Volume: 85, Issue:2

    Topics: Aspergillus; Caffeine; Chromatography, High Pressure Liquid; Fermentation; Flavonoids; Metabolomics; Plant Leaves; Tandem Mass Spectrometry; Tea; Xanthines

2020