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3-methylfentanyl and fentanyl

3-methylfentanyl has been researched along with fentanyl in 40 studies

*Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078) [MeSH]

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (30.00)	18.7374
1990's	11 (27.50)	18.2507
2000's	3 (7.50)	29.6817
2010's	10 (25.00)	24.3611
2020's	4 (10.00)	2.80

Authors

Authors	Studies
Chen, CY; Chen, XP; Shang, XE; Yang, YL	1
Jacobson, AE; Kim, CH; Rice, KC; Rothman, RB; Weber, RJ; Xu, H; Zhu, YC	1
Hibbs, J; Perper, J; Winek, CL	1
Clark, R; Frye, J; Harchelroad, F; Hecker, J; Jehle, D; Lucid, EJ; Martin, M	1
Li, Y; Yan, SM; Zhu, GZ	1
Chi, ZQ; Weng, JH; Xu, H; Xu, XR; Zhou, J; Zhu, YC	1
Band, L; Bykov, V; Greig, N; Jacobson, AE; Kim, CH; Newman, A; Rice, KC; Rothman, RB; Xu, H	1
Blake, JW; Tai, CL; Tai, HH; Tobin, T; Weckman, TJ; Woods, WE	1
Band, L; Bykov, V; Greig, N; Hauck-Newman, A; Jacobson, AE; Kim, CH; Rice, KC; Rothman, RB	1
Banks, HD; Ferguson, CP; Hsu, FL; Von Ostwalden, PW	1
Chen, J; Chi, ZQ; Xu, H; Yao, YH; Zhu, YC	1
Chi, ZQ; Zheng, WJ; Zhou, J	1
Chi, ZQ; Jin, WQ; Xu, H	1
Wu, JA; Xu, XR; Zhu, YC	1
Chen, WL; Chen, XJ; Chi, ZQ; Huang, ZM; Li, ZG; Zhang, HP; Zheng, WJ; Zhou, J	1
Chi, ZQ; Fang, SN; Ge, BL; Huang, ZM; Jin, WQ; Xia, XL; Xu, H; Zhu, YC	1
Chi, ZQ; Li, ZY; Ni, CH; Zhou, DH	1
Chi, ZQ; Chou, DP; Huang, ZM; Wu, RQ; Zhang, HP; Zhu, YC	1
Dai, QY; Fang, SN; Ge, BL; Huang, ZM; Li, QZ; Wu, RQ; Zhang, HP; Zhu, YC	1
Chen, KX; Ji, RY; Tang, Y; Wang, HW	1
Chen, XJ; Ji, RY; Wang, ZX; Zhu, YC	1
Brine, GA; Carroll, FI; Ni, Q; Partilla, JS; Rothman, RB; Stark, PA; Xu, H	1
Chen, KX; Ji, RY; Jiang, HL; Rong, SB; Wang, QM; Zhao, SR; Zhu, YC	1
Cao, Y; Chen, KX; Gu, JD; Huang, XQ; Ji, RY; Jiang, HL; Luo, XM; Rong, SB; Tan, XJ; Zhu, YC	1
Gergov, M; Lunetta, P; Ojanperä, I; Rasanen, I; Tiainen, E; Toivonen, S; Vuori, E	1
Gergov, M; Liiv, M; Ojanperä, I; Riikoja, A; Vuori, E	1
Dinger, J; Fritschi, G; Maurer, HH; Meyer, MR; Schwaninger, AE; Wissenbach, DK; Zapp, J	1
Brooker, IT; Dolinak, D; Gilson, TP; Kaspar, CK; Lavins, ES; Mazzola, CD; Perch, S; Schueler, HE; Sofalvi, S	1
Fogarty, MF; Logan, BK; Papsun, DM	1
Feyereisen, MC; Hamelin, EI; Johnson, RC; Kaplan, P; Seymour, C; Shaner, RL; Wharton, RE	1
Apollonio, LG; Brooker, IT; Clyde, CL; Gilson, TP; Goggin, C; Kaspar, CK; Kucmanic, J; Lavins, ES; Marshall, B; Mazzola, CD; Mitchell-Mata, CL; Moore, D; Rico, RN; Sofalvi, S	1
Gary, RD; McIntyre, IM; Mena, O; Trochta, A; Wright, J	1
Baumgartner, MR; Gascho, D; Gauthier, S; Jarmer, J; Kraemer, T; Staeheli, SN; Steuer, AE	1
Kraemer, T; Staeheli, SN; Steuer, AE; Williner, E	1
Inoue, H; Iwata, YT; Kanamori, T; Kuwayama, K; Segawa, H; Tsujikawa, K; Yamamuro, T	1
Flanagan, RJ; Hudson, S; Rab, E	1
Bruinsma, J; Eustace, S; Hoitink, M; Hulshof, J; Oldenhof, S; Ten Pierick, A; van den Berg, J	1
Eshleman, AJ; Janowsky, A; Nagarajan, S; Nilsen, A; Reed, JF; Torralva, R; Wolfrum, KM	1
Bazley, M; Blanchfield, J; Blanco, A; Logan, M; McGee, R; Smith, M; Stokes, R	1
Kacela, M; Wojcieszak, J; Zawilska, JB	1

Other Studies

40 other study(ies) available for 3-methylfentanyl and fentanyl

Article	Year
[Synthesis, analgesic activity and structure-activity relationship of 4-N-propionyl analogs of cis-3-methyl fentanyl]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:7 Topics: Analgesics, Opioid; Fentanyl; Molecular Structure; Structure-Activity Relationship	1992
(+)-cis-3-methylfentanyl and its analogs bind pseudoirreversibly to the mu opioid binding site: evidence for pseudoallosteric modulation. Neuropharmacology, 1991, Volume: 30, Issue:5 Topics: Allosteric Regulation; Analgesics; Animals; Endorphins; Fentanyl; Kinetics; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, mu	1991
An outbreak of designer drug--related deaths in Pennsylvania. JAMA, 1991, Feb-27, Volume: 265, Issue:8 Topics: Designer Drugs; Disease Outbreaks; Drug Overdose; Emergencies; Fentanyl; Humans; Morbidity; Pennsylvania; Substance-Related Disorders	1991
China White epidemic: an eastern United States emergency department experience. Annals of emergency medicine, 1991, Volume: 20, Issue:2 Topics: Adult; Analgesics; Disease Outbreaks; Drug Overdose; Emergencies; Female; Fentanyl; Humans; Male; Naloxone; Pennsylvania; Poisoning; Retrospective Studies	1991
[Synthesis and analgesic activity of the derivatives of 3-methyl fentanyl]. Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:11 Topics: Analgesics; Animals; Female; Fentanyl; Male; Mice; Structure-Activity Relationship	1990
[Studies on structure-activity relationships and receptor binding feature for 3-methylfentanyl derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:3 Topics: Analgesics; Animals; Fentanyl; Male; Mice; Rats; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship	1990
The potent opioid agonist, (+)-cis-3-methylfentanyl binds pseudoirreversibly to the opioid receptor complex in vitro and in vivo: evidence for a novel mechanism of action. Life sciences, 1990, Volume: 47, Issue:24 Topics: Animals; Brain; Catalepsy; Catatonia; Cell Membrane; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Injections, Intravenous; Male; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta	1990
Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses. American journal of veterinary research, 1989, Volume: 50, Issue:4 Topics: Alfentanil; Analgesics; Animals; Female; Fentanyl; Horses; Motor Activity; Radioimmunoassay; Sufentanil; Time Factors	1989
In vivo binding of (+)-cis methylfentanyl at the opiate receptor complex and behavioral correlates: evidence for a novel mechanism of action. NIDA research monograph, 1989, Volume: 95 Topics: Analgesics; Animals; Arousal; Brain; Fentanyl; Male; Motor Activity; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta	1989
Studies on the stereoselective synthesis of cis-3-methylfentanyl. NIDA research monograph, 1989, Volume: 95 Topics: Analgesics; Chemical Phenomena; Chemistry; Fentanyl; Humans; Stereoisomerism	1989
Potent 3-methylfentanyl analogs: morphine-like catalepsy and receptor binding characteristics. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:4 Topics: Analgesics; Animals; Catalepsy; Female; Fentanyl; Male; Mice; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, mu	1987
[Effects of potent analgesics, ohmefentanyl and mefentanyl, on respiration and electroencephalogram in rabbits]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:2 Topics: Analgesics; Animals; Electroencephalography; Female; Fentanyl; Male; Rabbits; Respiration	1986
[Absorption, distribution and excretion of 3-methyl[carbonyl-14C] fentanyl in mice]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:5 Topics: Absorption; Analgesics; Animals; Carbon Radioisotopes; Feces; Fentanyl; Male; Mice; Tissue Distribution	1986
[Studies on the quantitative structure-activity relationship (QSAR) of 3-methylfentanyl derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:4 Topics: Analgesics; Chemical Phenomena; Chemistry; Fentanyl; Structure-Activity Relationship	1985
[Analgesic activity and toxicity of potent analgesics, ohmefentanyl and mefentanyl]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:3 Topics: Analgesics; Animals; Blood Pressure; Electrocardiography; Electroencephalography; Fentanyl; Mice; Nalorphine; Rabbits; Rats	1984
Studies on synthesis and relationship between analgesic activity and receptor affinity for 3-methyl fentanyl derivatives. Scientia Sinica, 1981, Volume: 24, Issue:5 Topics: Analgesics; Animals; Binding Sites; Fentanyl; Mice; Receptors, Opioid; Structure-Activity Relationship	1981
[Interaction of seven 3-methyl fentanyl compounds with cerebroside sulfate (author's transl)]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:4 Topics: Analgesics; Animals; Cattle; Cerebrosides; Drug Interactions; Fentanyl; Naloxone; Receptors, Opioid; Swine	1981
[Studies on potent analgesics. VI. Modification of 4-N-propionyl group of cis-3-methylfentanyl and analgesic activity]. Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:8 Topics: Analgesics; Animals; Female; Fentanyl; Mice; Structure-Activity Relationship	1983
[Studies on potent analgesics. II. Synthesis an analgesic activity of the derivatives of 3-methyl fentanyl (author's transl)]. Yao xue xue bao = Acta pharmaceutica Sinica, 1981, Volume: 16, Issue:2 Topics: Analgesics; Animals; Female; Fentanyl; Male; Mice; Structure-Activity Relationship	1981
QSAR of 3-methylfentanyl derivatives studied with neural networks method. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:1 Topics: Analgesics; Fentanyl; Neural Networks, Computer; Structure-Activity Relationship	1995
[Stereoisomers of 3-methylfentanyl: synthesis, absolute configuration and analgesic activity]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:12 Topics: Analgesics; Animals; Female; Fentanyl; Mice; Stereoisomerism; Structure-Activity Relationship	1993
Stereochemical requirements for pseudoirreversible inhibition of opioid mu receptor binding by the 3-methylfentanyl congeners, RTI-46144 and its enantiomers: evidence for different binding domains. Synapse (New York, N.Y.), 1993, Volume: 15, Issue:4 Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Fentanyl; Ligands; Molecular Conformation; Rats; Receptors, Opioid, mu; Stereoisomerism	1993
Interaction models of 3-methylfentanyl derivatives with mu opioid receptors. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:2 Topics: Analgesics; Drug Interactions; Fentanyl; Models, Molecular; Receptors, Opioid, mu; Structure-Activity Relationship	1997
Molecular modeling on solvent effect and interaction mechanism of fentanyl analogs to mu-opioid receptor. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:1 Topics: Analgesics; Binding Sites; Drug Interactions; Fentanyl; Models, Molecular; Receptors, Opioid, mu; Solvents; Structure-Activity Relationship	2000
Blood levels of 3-methylfentanyl in 3 fatal poisoning cases. The American journal of forensic medicine and pathology, 2006, Volume: 27, Issue:4 Topics: Adult; Analgesics; Autopsy; Chromatography, Liquid; Female; Fentanyl; Forensic Medicine; Humans; Male; Mass Spectrometry; Poisoning	2006
An epidemic of fatal 3-methylfentanyl poisoning in Estonia. International journal of legal medicine, 2008, Volume: 122, Issue:5 Topics: Adult; Analgesics; Chromatography, Liquid; Disease Outbreaks; Estonia; Female; Fentanyl; Forensic Toxicology; Humans; Male; Molecular Structure; Poisoning; Sex Distribution; Stereoisomerism; Substance-Related Disorders; Tandem Mass Spectrometry	2008
Qualitative studies on the metabolism and the toxicological detection of the fentanyl-derived designer drugs 3-methylfentanyl and isofentanyl in rats using liquid chromatography-linear ion trap-mass spectrometry (LC-MS(n)). Analytical and bioanalytical chemistry, 2012, Volume: 402, Issue:3 Topics: Analgesics, Opioid; Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Designer Drugs; Fentanyl; Male; Mass Spectrometry; Rats; Rats, Wistar	2012
An LC-MS-MS Method for the Analysis of Carfentanil, 3-Methylfentanyl, 2-Furanyl Fentanyl, Acetyl Fentanyl, Fentanyl and Norfentanyl in Postmortem and Impaired-Driving Cases. Journal of analytical toxicology, 2017, Jul-01, Volume: 41, Issue:6 Topics: Analgesics, Opioid; Autopsy; Chromatography, Liquid; Driving Under the Influence; Enzyme-Linked Immunosorbent Assay; Fentanyl; Furans; Gas Chromatography-Mass Spectrometry; Humans; Substance Abuse Detection; Tandem Mass Spectrometry	2017
Analysis of cis and trans 3-methylfentanyl by liquid chromatography-high resolution mass spectrometry and findings in forensic toxicology casework. Drug testing and analysis, 2018, Volume: 10, Issue:9 Topics: Adult; Calibration; Cause of Death; Chromatography, High Pressure Liquid; Drug Overdose; Female; Fentanyl; Forensic Toxicology; Humans; Illicit Drugs; Limit of Detection; Male; Mass Spectrometry; Reference Standards; Reproducibility of Results; Stereoisomerism; Substance Abuse Detection; Young Adult	2018
Determination of Fentanyl Analog Exposure Using Dried Blood Spots with LC-MS-MS. Journal of analytical toxicology, 2019, May-01, Volume: 43, Issue:4 Topics: Analgesics, Opioid; Autopsy; Chromatography, Liquid; Data Accuracy; Dried Blood Spot Testing; Drug Overdose; Fentanyl; Furans; Hematocrit; Humans; Humidity; Illicit Drugs; Substance Abuse Detection; Tandem Mass Spectrometry; United States	2019
Unique Structural/Stereo-Isomer and Isobar Analysis of Novel Fentanyl Analogues in Postmortem and DUID Whole Blood by UHPLC-MS-MS. Journal of analytical toxicology, 2019, Oct-17, Volume: 43, Issue:9 Topics: Analgesics, Opioid; Autopsy; Chromatography, High Pressure Liquid; Fentanyl; Humans; Isomerism; Limit of Detection; Tandem Mass Spectrometry	2019
An Acute Butyr-Fentanyl Fatality: A Case Report with Postmortem Concentrations. Journal of analytical toxicology, 2016, Volume: 40, Issue:2 Topics: Adult; Analgesics, Opioid; Cocaine; Drug Overdose; Enzyme-Linked Immunosorbent Assay; Fatal Outcome; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Male; Opioid-Related Disorders; Substance Abuse, Intravenous	2016
Time-dependent postmortem redistribution of butyrfentanyl and its metabolites in blood and alternative matrices in a case of butyrfentanyl intoxication. Forensic science international, 2016, Volume: 266 Topics: Autopsy; Chromatography, Liquid; Fentanyl; Humans; Postmortem Changes; Time Factors; Tissue Distribution	2016
Studies on the metabolism of the fentanyl-derived designer drug butyrfentanyl in human in vitro liver preparations and authentic human samples using liquid chromatography-high resolution mass spectrometry (LC-HRMS). Drug testing and analysis, 2017, Volume: 9, Issue:7 Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Designer Drugs; Fentanyl; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Microsomes, Liver	2017
Metabolism of Butyrylfentanyl in Fresh Human Hepatocytes: Chemical Synthesis of Authentic Metabolite Standards for Definitive Identification. Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:4 Topics: Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Fentanyl; Hepatocytes; Humans; Illicit Drugs; Microsomes, Liver; Reference Standards	2019
Detection of fentanyl and fentanyl analogues in biological samples using liquid chromatography-high resolution mass spectrometry. Forensic science international, 2019, Volume: 300 Topics: Adult; Analgesics, Opioid; Central Nervous System Depressants; Chromatography, Liquid; Cocaine; Ethanol; Fentanyl; Humans; Mass Spectrometry; Middle Aged; Morphine; Opioid-Related Disorders; Substance Abuse Detection; Young Adult	2019
Identification of a novel fentanyl analog: p-Hydroxy-butyrylfentanyl. Drug testing and analysis, 2020, Volume: 12, Issue:1 Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Magnetic Resonance Spectroscopy	2020
Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors. Biochemical pharmacology, 2020, Volume: 182 Topics: Analgesics, Opioid; Animals; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Fentanyl; Furans; Humans; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Structure, Secondary; Receptors, Opioid, kappa; Structure-Activity Relationship; Treatment Outcome	2020
A Semi-quantitative method for the detection of fentanyl using surface-enhanced Raman scattering (SERS) with a handheld Raman instrument. Journal of forensic sciences, 2021, Volume: 66, Issue:2 Topics: Analgesics, Opioid; Fentanyl; Furans; Humans; Illicit Drugs; Least-Squares Analysis; Limit of Detection; Spectrum Analysis, Raman	2021
Use of fentanyl, butyrfentanyl and furanylfentanyl as discussed on Polish online forums devoted to 'designer drugs'. Psychiatria polska, 2022, Apr-30, Volume: 56, Issue:2 Topics: Adolescent; Analgesics, Opioid; Fentanyl; Furans; Humans; Poland	2022