Page last updated: 2024-09-04

3-methylcytosine and cytosine

3-methylcytosine has been researched along with cytosine in 21 studies

Compound Research Comparison

Studies
(3-methylcytosine)
Trials
(3-methylcytosine)
Recent Studies (post-2010)
(3-methylcytosine)
Studies
(cytosine)
Trials
(cytosine)
Recent Studies (post-2010) (cytosine)
230811,1681423,214

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's0 (0.00)18.2507
2000's9 (42.86)29.6817
2010's4 (19.05)24.3611
2020's5 (23.81)2.80

Authors

AuthorsStudies
Bertaux, O; N'Guyen Công, H; Valencia, R1
Kawasaki, H; Ninomiya, S; Yuki, H1
Saffhill, R1
Hausinger, RP; Henshaw, TF; Lindahl, T; Sedgwick, B; Trewick, SC1
Bates, PA; Duncan, T; Koivisto, P; Lindahl, T; Sedgwick, B; Trewick, SC1
Jiricny, J1
Falnes, PØ; Rognes, T1
Koivisto, P; Lindahl, T; Robins, P; Sedgwick, B1
Bratlie, MS; Drabløs, F1
Aas, PA; Bjørk, A; Doughty, RW; Falnes, PØ; Klungland, A; Krokan, HE; Lauritzen, KH; Liabakk, NB; Nordstrand, LM; Reite, K; Ringvoll, J; Talstad, V; Vågbø, CB1
Aas, PA; Akbari, M; Feyzi, E; Hagen, L; Kavli, B; Krokan, HE; Liabakk, NB; Otterlei, M; Slupphaug, G; Sundheim, O; Talstad, VA; Vågbø, CB; Westbye, MP1
Hunt, JF; Yu, B1
Gordenin, DA; Resnick, MA; Yang, Y1
Furrer, A; van Loon, B1
Beck, S; Pataillot-Meakin, T; Pillay, N1
Fusamae, Y; Harada, K; Hase, H; Hirata, K; Jingushi, K; Kawaguchi, M; Kitae, K; Ooshio, I; Tsujikawa, K; Ueda, Y1
Alkuraya, FS; Alsaif, HS; Faqeih, E; Fu, D; Lentini, JM1
Akula, D; Anindya, R; O'Connor, TR1
Ayadi, L; Bourguignon-Igel, V; Helm, M; Marchand, V; Motorin, Y1
Aas, PA; Bjørås, M; Erlandsen, HO; Fonseca, DM; Hagen, L; Iveland, TS; Mosammaparast, N; Palibrk, V; Rabe, R; Sharma, A; Slupphaug, G; Sporsheim, B; Vågbø, CB; Wollen, KL1
Bargabos, R; Chen, C; Fu, D; Lentini, JM1

Reviews

2 review(s) available for 3-methylcytosine and cytosine

ArticleYear
DNA repair: bioinformatics helps reverse methylation damage.
    Current biology : CB, 2002, Dec-23, Volume: 12, Issue:24

    Topics: Adenine; Computational Biology; Cytosine; DNA Methylation; DNA Repair; Escherichia coli; Escherichia coli Proteins; Mixed Function Oxygenases

2002
DNA repair by bacterial AlkB proteins.
    Research in microbiology, 2003, Volume: 154, Issue:8

    Topics: Adenine; Alkylation; Bacterial Proteins; Cytosine; DNA Repair; Escherichia coli Proteins; Mixed Function Oxygenases; Molecular Sequence Data; Oxygenases; Phylogeny; Sequence Alignment; Sequence Homology, Amino Acid

2003

Other Studies

19 other study(ies) available for 3-methylcytosine and cytosine

ArticleYear
Separation of naturally occurring or induced methylated nucleobases of DNA by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1985, May-29, Volume: 325, Issue:1

    Topics: Adenine; Animals; Cattle; Chromatography, High Pressure Liquid; Cytosine; DNA; Euglena gracilis; Hydrolysis; Methylnitrosourea; Spectrophotometry, Infrared; Thymus Gland

1985
High-performance liquid chromatographic determination of 3-methylcytosine in deoxyribonucleic acid treated with carcinogenic methylating agents in vitro and in vivo.
    Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:3

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cytosine; Dimethylnitrosamine; DNA; Liver; Male; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thymus Gland

1985
Differences in the promutagenic nature of 3-methylcytosine as revealed by DNA and RNA polymerising enzymes.
    Carcinogenesis, 1984, Volume: 5, Issue:5

    Topics: Cytosine; DNA Polymerase I; DNA Replication; Escherichia coli; Mutagens; Poly C; RNA Polymerase I; Templates, Genetic; Transcription, Genetic

1984
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage.
    Nature, 2002, Sep-12, Volume: 419, Issue:6903

    Topics: Adenine; Alkylation; Chromatography, High Pressure Liquid; Cytosine; DNA Damage; DNA Methylation; DNA Repair; DNA, Bacterial; DNA, Single-Stranded; Edetic Acid; Escherichia coli; Escherichia coli Proteins; Ethanol; Formaldehyde; Gas Chromatography-Mass Spectrometry; Hydroxylation; Mixed Function Oxygenases; Mutation; Oxidation-Reduction; Oxygen

2002
Reversal of DNA alkylation damage by two human dioxygenases.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-24, Volume: 99, Issue:26

    Topics: Adenine; AlkB Homolog 1, Histone H2a Dioxygenase; Alkylation; Amino Acid Sequence; Cytosine; DNA Damage; DNA Repair; DNA Repair Enzymes; Escherichia coli Proteins; Humans; Mixed Function Oxygenases; Molecular Sequence Data

2002
Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: Adenine; Binding Sites; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; DNA Repair; DNA, Single-Stranded; Dose-Response Relationship, Drug; Escherichia coli; Humans; Hydrogen-Ion Concentration; Mixed Function Oxygenases; Models, Chemical; Polymers; Thymine; Time Factors

2004
Bioinformatic mapping of AlkB homology domains in viruses.
    BMC genomics, 2005, Jan-03, Volume: 6

    Topics: Adenine; Amino Acid Sequence; Chromosome Mapping; Computational Biology; Cytosine; DNA Damage; DNA Methylation; DNA Repair; Escherichia coli; Escherichia coli Proteins; Genome, Viral; Genomics; Humans; Methylation; Mixed Function Oxygenases; Molecular Sequence Data; Oxygen; Phylogeny; Protein Structure, Tertiary; RNA; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2005
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
    The EMBO journal, 2006, May-17, Volume: 25, Issue:10

    Topics: Adenine; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Alleles; Animals; Cell Line; Cytosine; Dioxygenases; DNA; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Humans; Male; Mice; Mice, Knockout; Molecular Structure; Tissue Distribution

2006
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
    The Journal of biological chemistry, 2008, Sep-05, Volume: 283, Issue:36

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Cytosine; Dioxygenases; DNA Methylation; DNA Repair Enzymes; DNA, Mitochondrial; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; HeLa Cells; Humans; Mitochondrial Proteins; Mixed Function Oxygenases; RNA; RNA Processing, Post-Transcriptional; RNA, Mitochondrial; Sequence Homology, Amino Acid

2008
Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Aug-25, Volume: 106, Issue:34

    Topics: Adenine; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cytosine; DNA Repair; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanosine; Kinetics; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Oxidation-Reduction; Oxygen; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Thymine

2009
A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast.
    DNA repair, 2010, Aug-05, Volume: 9, Issue:8

    Topics: Cytosine; DNA Breaks, Double-Stranded; DNA Repair; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Methyl Methanesulfonate; Models, Genetic; Mutagenesis; Saccharomyces cerevisiae

2010
Handling the 3-methylcytosine lesion by six human DNA polymerases members of the B-, X- and Y-families.
    Nucleic acids research, 2014, Volume: 42, Issue:1

    Topics: Cell Line; Cytosine; DNA; DNA Damage; DNA Polymerase iota; DNA Repair; DNA-Directed DNA Polymerase; Humans

2014
3-methylcytosine in cancer: an underappreciated methyl lesion?
    Epigenomics, 2016, Volume: 8, Issue:4

    Topics: Biomarkers, Tumor; Cytosine; DNA Damage; DNA Methylation; DNA Repair; Humans; Neoplasms

2016
AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells.
    Scientific reports, 2017, 02-13, Volume: 7

    Topics: Adenine; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 5, RNA Demethylase; Animals; Cattle; Cell Line, Tumor; Cytosine; Demethylation; Gene Knockdown Techniques; Humans; Methylation; Pancreatic Neoplasms; Protein Biosynthesis; Recombinant Proteins; RNA, Transfer; Substrate Specificity

2017
DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification.
    Nature communications, 2020, 05-19, Volume: 11, Issue:1

    Topics: Age of Onset; Cell Line; Cytosine; Epilepsy; Humans; Nucleic Acid Conformation; Protein Binding; RNA, Transfer, Arg; tRNA Methyltransferases

2020
Oxidative demethylase ALKBH5 repairs DNA alkylation damage and protects against alkylation-induced toxicity.
    Biochemical and biophysical research communications, 2021, 01-01, Volume: 534

    Topics: AlkB Homolog 5, RNA Demethylase; Alkylating Agents; Cytosine; Demethylation; DNA Adducts; DNA Damage; DNA Methylation; DNA Repair; HEK293 Cells; Humans; Mesylates

2021
AlkAniline-Seq: A Highly Sensitive and Specific Method for Simultaneous Mapping of 7-Methyl-guanosine (m
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2298

    Topics: Cell Line; Cytosine; Guanosine; HEK293 Cells; High-Throughput Nucleotide Sequencing; Humans; Methylation; RNA; Sensitivity and Specificity; Sequence Analysis, RNA

2021
ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.
    Journal of translational medicine, 2021, 07-03, Volume: 19, Issue:1

    Topics: Adenosine; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Cytosine; DNA Helicases; Humans; Ribosomes; RNA Helicases; RNA, Messenger; Transcription Factors; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2021
Methyltransferase METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:4

    Topics: Anticodon; Cytosine; Humans; Methyltransferases; Mitochondria; RNA, Transfer

2022