3-methylcholanthrene and thyroxine

3-methylcholanthrene has been researched along with thyroxine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's6 (23.08)18.2507
2000's5 (19.23)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Catinot, R; Cordier, A; de Sandro, V; Kriszt, W; Richert, L1
Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L1
Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP1
Gupta, MP; Khanduja, KL; Koul, A; Koul, IB; Pathak, CM; Sharma, RR; Vaidyanathan, S1
Baumann, J; Besedovsky, HO; del Rey, A; Girard, J; Normann, S; Schardt, M; Sorkin, E1
Mannering, GJ1
Moon, RC; Newman, WC2
Bastomsky, CH; Papapetrou, PD1
Fernandez, RC; Moon, RC; Newman, WC; Slayden, RM1
Kato, R; Oshima, T; Takayanagi, M1
Hirata, K; Nakao, K; Sakamoto, Y; Wada, F1
Acuff, M; Gruenstein, M; Meranze, DR; Shimkin, MB1
de-Andrade-Silva, E; de-Araujo, PS; Raw, I1
Axelrod, J; Hoffman, AR; Paul, SM1
Brouwer, A; Joe, CT; Kaptein, E; van den Berg, KJ; van Engelen, JG; van Raaij, JA; van Toor, H; Visser, TJ1
Jemnitz, K; Vereczkey, L1
Hashmi, R; Hood, A; Klaassen, CD1
Jemnitz, K; Monostory, K; Vereczkey, L; Veres, Z1
Hood, A; Klaassen, CD2
Klaassen, CD; Vansell, NR2
BENELLI, C; GEYER, A; MAZER, A1
ARCOS, JC; GOSCH, HH; ZICKAFOOSE, D1
Klaassen, CD; Richardson, TA1

Other Studies

26 other study(ies) available for 3-methylcholanthrene and thyroxine

ArticleYear
Male rat hepatic UDP-glucuronosyltransferase activity toward thyroxine. Activation and induction properties--relation with thyroxine plasma disappearance rate.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: Animals; Detergents; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine; Triiodothyronine

1992
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1991
Role of cytochrome P450 in the control of the production of erythropoietin.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured

1990
Effect of phenobarbital & 3-methylcholanthrene treatment on thyroid hormones in rat.
    The Indian journal of medical research, 1987, Volume: 86

    Topics: Animals; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine; Triiodothyronine

1987
Changes in plasma hormone profiles after tumor transplantation into syngeneic and allogeneic rats.
    International journal of cancer, 1985, Aug-15, Volume: 36, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corticosterone; Female; Gonadal Steroid Hormones; Hormones; Insulin; Male; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains; Thyroxine

1985
Properties of cytochrome P-450 as affected by environmental factors: qualitative changes due to administration of polycyclic hydrocarbons.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Transport; Environment; Hydrocarbons; Hydrogen-Ion Concentration; Methylcholanthrene; Microsomes, Liver; Morpholines; Phenobarbital; Polycyclic Compounds; Spectrum Analysis; Thyroxine

1971
Altered thyroxine metabolism resulting from the chemical carcinogen 3-methylcholanthrene.
    Endocrinology, 1967, Volume: 80, Issue:5

    Topics: Animals; Chromatography, Paper; Feces; Iodine Isotopes; Methylcholanthrene; Rats; Thyroid Function Tests; Thyroxine

1967
The effect of methylcholanthrene on biliary thyroxine excretion in normal and Gunn rats.
    The Journal of endocrinology, 1973, Volume: 56, Issue:2

    Topics: Animals; Bile; Biliary Fistula; Blood Proteins; Common Bile Duct; Depression, Chemical; Female; Glucuronates; Half-Life; Iodine; Iodine Isotopes; Jaundice; Male; Methylcholanthrene; Mice; Protein Binding; Rats; Rats, Inbred Strains; Stimulation, Chemical; Thyroid Gland; Thyroxine

1973
Accelerated biliary thyroxine secretion in rats treated with 3-methylcholanthrene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:3

    Topics: Animals; Bile; Female; Iodine Isotopes; Liver; Metabolic Clearance Rate; Methylcholanthrene; Rats; Thyroxine

1971
Differences in the oxidative metabolism of drugs by liver microsomes.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine

1969
Participation of the microsomal electron transport system involving cytochrome P-450 in 7alpha-hydroxylation of cholesterol.
    Journal of biochemistry, 1969, Volume: 66, Issue:5

    Topics: Animals; Antibodies; Biliary Fistula; Carbon Isotopes; Carbon Monoxide; Cholesterol; Cytochromes; Electron Transport; Fasting; Hydrocortisone; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Proteins; Rabbits; Rats; Thyroxine

1969
The role of the thyroid in hydrocarbon-induced mammary carcinogenesis in rats.
    Cancer research, 1968, Volume: 28, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Thyroid Gland; Thyroidectomy; Thyroxine

1968
Chemically induced mammary cancer in rats with altered thyroid function.
    Cancer research, 1968, Volume: 28, Issue:5

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Organ Size; Rats; Thiouracil; Thyroid Gland; Thyroxine

1968
Effect of drugs and hormones on rat liver dimethylaminoazobenzene reductase activity.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1982, Volume: 15, Issue:1

    Topics: Allylisopropylacetamide; Amitrole; Animals; Cytochrome P-450 Enzyme System; Female; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains; Streptozocin; Thyroxine

1982
Estrogen-2-hydroxylase in the rat. Distribution and response to hormonal manipulation.
    Biochemical pharmacology, 1980, Jan-01, Volume: 29, Issue:1

    Topics: Animals; Castration; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A1; Enzyme Induction; Estrogens; Female; Hormones; Male; Methylcholanthrene; Phenobarbital; Rats; Steroid Hydroxylases; Thyroidectomy; Thyroxine

1980
Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions.
    Endocrinology, 1993, Volume: 133, Issue:5

    Topics: Animals; Cetomacrogol; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Gunn; Rats, Wistar; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1993
Ion-pair high-performance liquid chromatographic separation of two thyroxine glucuronides formed by rat liver microsomes.
    Journal of chromatography. B, Biomedical applications, 1996, Jun-07, Volume: 681, Issue:2

    Topics: Acylation; Animals; Chromatography, High Pressure Liquid; Drug Stability; Glucuronates; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Phenols; Rats; Rats, Wistar; Temperature; Thyroxine

1996
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
    Toxicology and applied pharmacology, 1999, Oct-15, Volume: 160, Issue:2

    Topics: Animals; Cell Count; Cell Division; Chlorodiphenyl (54% Chlorine); Enzyme Activation; Hyperplasia; Hypertrophy; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1999
Glucuronidation of thyroxine in primary monolayer cultures of rat hepatocytes: in vitro induction of UDP-glucuronosyltranferases by methylcholanthrene, clofibrate, and dexamethasone alone and in combination.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Clofibrate; Dexamethasone; Drug Interactions; Enzyme Induction; Glucuronosyltransferase; Hypolipidemic Agents; Liver; Methylcholanthrene; Rats; Thyroxine

2000
Effects of microsomal enzyme inducers on outer-ring deiodinase activity toward thyroid hormones in various rat tissues.
    Toxicology and applied pharmacology, 2000, Mar-15, Volume: 163, Issue:3

    Topics: Animals; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Iodide Peroxidase; Iodine Radioisotopes; Liver; Male; Methylcholanthrene; Microsomes; Organ Size; Proteins; Rats; Rats, Sprague-Dawley; Thyroid Hormones; Thyrotropin; Thyroxine; Tissue Distribution; Triiodothyronine

2000
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T(4)) and triiodothyronine (T(3)) glucuronidation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:1

    Topics: Animals; Chlorodiphenyl (54% Chlorine); Detergents; Enzyme Induction; Glucuronides; Glucuronosyltransferase; In Vitro Techniques; Iodine Radioisotopes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine

2000
Increased biliary excretion of thyroxine by microsomal enzyme inducers.
    Toxicology and applied pharmacology, 2001, Nov-01, Volume: 176, Issue:3

    Topics: Animals; Antithyroid Agents; Bile; Carcinogens; Chlorodiphenyl (54% Chlorine); Glucuronides; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyrotropin; Thyroxine

2001
Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:3

    Topics: Animals; Blotting, Northern; Chlorodiphenyl (54% Chlorine); Electrophoresis, Agar Gel; Enzyme Induction; Glucuronosyltransferase; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity; Thyroid Hormones; Thyroxine; Transcription, Genetic; Triiodothyronine

2002
[Experimental study on the relation between thyroid function and induced cancer in mouse].
    Annales d'endocrinologie, 1953, Volume: 14, Issue:6

    Topics: Animals; Hormones; Methylcholanthrene; Mice; Neoplasms, Experimental; Pituitary Gland; Pituitary Gland, Anterior; Thiouracil; Thyroid Gland; Thyroxine

1953
Fine structural alterations in cell particles during chemical carcinogenesis. III. Selective action of hepatic carcinogens other than 3'-methyl-4-dimethylaminoazobenzene on different types of mitochondrial swelling. Effect of stimulated liver growth.
    The Journal of biophysical and biochemical cytology, 1961, Volume: 10

    Topics: Animals; Carcinogenesis; Carcinogens; Guinea Pigs; Liver; Methylcholanthrene; Methyldimethylaminoazobenzene; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Rats; Thyroxine

1961
Disruption of thyroid hormone homeostasis in Ugt1a-deficient Gunn rats by microsomal enzyme inducers is not due to enhanced thyroxine glucuronidation.
    Toxicology and applied pharmacology, 2010, Oct-01, Volume: 248, Issue:1

    Topics: Animals; Cell Proliferation; Chlorodiphenyl (54% Chlorine); Glucuronosyltransferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Rats, Gunn; Rats, Wistar; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2010