3-methylcholanthrene has been researched along with theophylline in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Bertram, JS | 1 |
| Lowitt, S; Szentivanyi, A; Williams, JF | 1 |
| Lohmann, SM; Miech, RP | 1 |
| Lesko, L; McMahon, TF; Peggins, JO; Weiner, M | 1 |
| Grishanova, AIu; Guliaeva, LF; Mishin, VM; Vavilin, VA | 1 |
| Berthou, F; Dreano, Y; Guillouzo, A; Mondine, P; Ratanasavanh, D; Riche, C | 1 |
| Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT | 1 |
| Gelboin, HV; Park, SS; Slusher, LB; Vesell, ES | 1 |
| Burgison, RM; Dietz, AJ | 1 |
| Huberman, E; Sachs, L; Yamasaki, H | 1 |
| Cupissol, D; Goldstein, AL; Rey, A; Serrou, B | 1 |
| Fujiwara, I; Mizuki, Y; Sekine, Y; Yamaguchi, T | 1 |
| Bezek, S; Kukan, M; Pool, WF; Woolf, TF | 1 |
| Bélanger, PM; Dalkara, S; El-Kadi, AO; Kurdi, J; Maurice, H; Ong, H; Souich, P | 1 |
| Horsmans, Y; Spatzenegger, M; Verbeeck, RK | 1 |
| Kelly, JH; Sussman, NL | 1 |
| Audus, KL; Avery, ML; Meek, CE | 1 |
| Lee, JH; Lee, MG; Yang, KH | 1 |
19 other study(ies) available for 3-methylcholanthrene and theophylline
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Modulation of cellular interactions between C3H/10T1/2 cells and their transformed counterparts by phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Contact Inhibition; Cyclic AMP; Embryo, Mammalian; Fibroblasts; In Vitro Techniques; Methylcholanthrene; Mice; Phosphodiesterase Inhibitors; Theophylline | 1979 |
Effects of phenobarbital and 3-methylcholanthrene pretreatment on the plasma half-life and urinary excretion profile of theophylline and its metabolites in rats.
Topics: Animals; Biotransformation; Feces; Half-Life; Male; Methylcholanthrene; Phenobarbital; Rats; Theophylline; Time Factors | 1979 |
Theophylline metabolism by the rat liver microsomal system.
Topics: Aldehyde Oxidoreductases; Animals; Cytosol; Female; Half-Life; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Proadifen; Rats; Theophylline; Time Factors; Xanthine Oxidase | 1976 |
The effects of age on the pharmacokinetics and biotransformation of theophylline in vivo and in vitro in the Mongolian gerbil (Meriones unguiculatus).
Topics: Aging; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Female; Gerbillinae; Half-Life; In Vitro Techniques; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Theophylline | 1992 |
[Theophylline metabolism by rat liver microsomal monooxygenases].
Topics: Animals; Antibodies, Monoclonal; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Neprilysin; Rats; Rats, Inbred Strains; Theophylline; Uric Acid | 1990 |
Methylcholanthrene but not phenobarbital enhances caffeine and theophylline metabolism in cultured adult human hepatocytes.
Topics: Adult; Biotransformation; Caffeine; Cells, Cultured; Humans; Kinetics; Liver; Methylcholanthrene; Phenobarbital; Theophylline | 1990 |
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1990 |
Studies on the metabolism of aminopyrine, antipyrine and theophylline using monoclonal antibodies to cytochrome P-450 isozymes purified from rat liver.
Topics: Aminopyrine; Animals; Antibodies, Monoclonal; Antibody Specificity; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Activation; Epitopes; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Theophylline | 1987 |
The biotransformation of 8-ethylthio-6-thiotheophylline sodium in vivo.
Topics: Amines; Animals; Carbon Tetrachloride; Chromatography, Thin Layer; Dactinomycin; Depression, Chemical; Hypnotics and Sedatives; Male; Methylcholanthrene; Oils; Phenobarbital; Proadifen; Rats; Sleep; Stimulation, Chemical; Theophylline; Time Factors | 1968 |
Genetic control of the regulation of cell susceptibility to carcinogenic polycyclic hydrocarbons by cyclic AMP.
Topics: Aminophylline; Animals; Benz(a)Anthracenes; Benzopyrenes; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cricetinae; Drug Synergism; Haplorhini; HeLa Cells; Humans; Hydrocarbons; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Prostaglandins E; Rats; Stimulation, Chemical; Theophylline | 1974 |
Decrease of tumor growth in mice after intravenous thymosin-treated bone marrow cell injection.
Topics: Animals; Bone Marrow Transplantation; Cell Division; Levamisole; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Theophylline; Thymosin; Thymus Hormones; Time Factors | 1982 |
Structure-related inhibitory effect of antimicrobial enoxacin and derivatives on theophylline metabolism by rat liver microsomes.
Topics: Animals; Anti-Infective Agents; Crystallography, X-Ray; Electrochemistry; Enoxacin; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Molecular Structure; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Theophylline; Uric Acid | 1996 |
The effect of cytochromes P4501A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations.
Topics: Animals; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Enoxacin; Enzyme Induction; Etimizol; Glucuronidase; Glutathione; Liver; Male; Methylcholanthrene; Rats; Rats, Wistar; Tacrine; Theophylline | 1996 |
Effect of hypoxia alone or combined with inflammation and 3-methylcholanthrene on hepatic cytochrome P450 in conscious rabbits.
Topics: Animals; Apoproteins; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Down-Regulation; Hypoxia; Inflammation; Irritants; Liver; Male; Methylcholanthrene; Phosphodiesterase Inhibitors; Rabbits; Theophylline; Turpentine | 1999 |
Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Induction; Enzyme Inhibitors; Injections, Intraperitoneal; Intestine, Small; Ketoconazole; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Wistar; Theobromine; Theophylline | 2000 |
A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition.
Topics: Cell Line; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Fluorescence; Humans; Methylcholanthrene; Oxazines; Theophylline | 2000 |
The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.
Topics: Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Methylcholanthrene; Microsomes, Liver; Smoking; Theophylline; Trophoblasts; Tumor Cells, Cultured | 2003 |
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
Topics: Animals; Area Under Curve; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activators; Half-Life; Infusions, Intravenous; Isoniazid; Metabolic Clearance Rate; Methylcholanthrene; Orphenadrine; Phosphodiesterase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Theophylline; Uric Acid; Weight Gain | 2008 |