3-methylcholanthrene has been researched along with spironolactone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Jaeger, RJ; Moslen, MT; Murphy, SD; Reynolds, ES; Szabo, S | 1 |
| Klaassen, CD | 3 |
| Black, VH | 1 |
| Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B | 1 |
| Gillette, JR; Stripp, B | 1 |
| Gillette, JR | 1 |
| Hänninen, O; Marselos, M | 1 |
| Blascheck, JA; Garg, BD; Kovacs, K | 1 |
| Bellward, GD; Gontovnick, LS; Sunahara, G | 1 |
| Ando, M; Ishii, K; Kamataki, T; Kato, R; Yamazoe, Y | 1 |
1 review(s) available for 3-methylcholanthrene and spironolactone
| Article | Year |
|---|---|
Effects of steroids upon the liver ultrastructure.
Topics: Animals; Benzopyrenes; Desoxycorticosterone; Endocrine Glands; Enzyme Induction; Glucocorticoids; Glycogen; Gonadal Steroid Hormones; Humans; Lipid Metabolism; Liver; Membranes; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Norpregnenes; Phenobarbital; Pregnenolone Carbonitrile; Protein Biosynthesis; RNA; Spironolactone; Steroids | 1973 |
12 other study(ies) available for 3-methylcholanthrene and spironolactone
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system.
Topics: Animals; Aroclors; Carcinogens; Cell Membrane; Cytochrome P-450 Enzyme System; Dichloroethylenes; Endoplasmic Reticulum; Enzyme Induction; Glutathione; Hexachlorobenzene; Hydrocarbons, Chlorinated; Liver; Liver Neoplasms; Male; Methylcholanthrene; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Vinyl Chloride; Vinyl Compounds | 1975 |
Effect of microsomal enzyme inducers on the biliary excretion of an exogenous load of bilirubin in newborn rats.
Topics: Age Factors; Animals; Animals, Newborn; Bile; Bilirubin; Enzyme Induction; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone | 1976 |
Immunodetectable cytochromes P450 I, II, and III in guinea pig adrenal--hormone responsiveness and relationship to capacity for xenobiotic metabolism.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Guinea Pigs; Immunoblotting; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Molecular Weight; Rats; Sex Characteristics; Spironolactone; Tissue Distribution | 1990 |
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone | 1972 |
Effect of various inducers on electron transport system associated with drug metabolism by liver microsomes.
Topics: Animals; Cytochromes; Electron Transport; Female; Hexobarbital; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morpholines; NADP; Oxidation-Reduction; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Rats; Spironolactone; Stimulation, Chemical | 1971 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.
Topics: Analysis of Variance; Animals; Bile; Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Induction; Lethal Dose 50; Liver; Male; Methylcholanthrene; Microsomes; Myocardium; Organ Size; Ouabain; Paralysis; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors; Tritium; Zoxazolamine | 1974 |
Stimulation of the development of the hepatic excretory mechanism for ouabain in newborn rats with microsomal enzyme inducers.
Topics: Aging; Animals; Animals, Newborn; Bile; Enzyme Induction; Liver; Methylcholanthrene; Microsomes, Liver; Ouabain; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors; Tritium | 1974 |
Enhancement of D-glucuronolactone and acetaldehyde dehydrogenase activities in the rat liver by inducers of drug metabolism.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; DDT; Enzyme Induction; Germ-Free Life; Hydrogen-Ion Concentration; Lactones; Liver; Male; Methylcholanthrene; Oils; Organ Size; Phenobarbital; Proteins; Pyrazoles; Rats; Spironolactone | 1974 |
A comparative ultrastructural study on drug-induced proliferation of smooth-surfaced endoplasmic reticulum in hepatocytes.
Topics: Animals; Endoplasmic Reticulum; Female; Liver; Methylcholanthrene; Microscopy, Electron; Organoids; Phenobarbital; Pregnenolone; Rats; Spironolactone | 1971 |
Nonadditive effects of combined in vivo hepatic microsomal enzyme inducers in the Wistar rat.
Topics: Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Spironolactone; Stilbenes | 1983 |
Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats.
Topics: Animals; Dealkylation; Enzyme Induction; Female; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Sex Factors; Spironolactone; Umbelliferones | 1980 |