3-methylcholanthrene and safrole

3-methylcholanthrene has been researched along with safrole in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199029 (64.44)18.7374
1990's13 (28.89)18.2507
2000's3 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, RG; Farber, E; Joly, JG; Murray, RK; Sharma, RN1
Cameron, RG; Farber, E; Griffin, MJ; Joly, JG; Murray, RK; Sharma, RN1
Bridges, JW; Dickins, M; Fennell, TR1
Bridges, JW; Dickins, M; Elcombe, CR; Netter, KJ1
Bridges, JW; McPherson, FJ; Parke, DV1
Horbach, GJ; Kremers, P; Rietjens, IM; Van Asten, JG; Van Bezooijen, CF1
Albores, A; Bach, PH; Bridges, JW; Cebrian, ME; Connelly, JC1
Hsieh, CY; Huang, JD1
Balvers, WG; Boersma, MG; Rietjens, IM; Veeger, C1
Hanioka, N; Ishida, C; Koga, N; Saeki, HK; Yoshimura, H1
Boobis, AR; Davies, DS; Edwards, RJ; Levin, W; Sesardic, D; Thomas, PE1
Boobis, AR; Cole, KJ; Davies, DS; Edwards, RJ; Levin, W; Sesardic, D; Thomas, PE1
Clement, B; Kunze, T1
Kelley, M; Safe, S; Womack, J1
Etoh, H; Misawa, S; Tanaka, E1
Gessner, T; Olson, JR; Wroblewski, VJ1
Batt, AM; Delatour, P; Masson, C; Mothe, O; Siest, G; Souhaili-El Amri, H; Totis, M1
Ioannides, C; Lewis, DF; Parke, DV; Rodrigues, AD1
Campanile, C; Haniu, M; Levin, W; Maines, SL; Mendez-Picon, G; Parker, G; Shively, JE; Thomas, PE; Watkins, PB; Wrighton, SA1
Smith, AG; Stewart, FP1
Degawa, M; Hashimoto, Y; Kojima, M; Sato, Y1
Adang, A; Müller, F; van Bladeren, PJ; van Ommen, B1
Chen, YT; Ding, JH; Kato, T1
Juchau, MR; Namkung, MJ; Nelson, SD; Porubek, DJ1
Gonzalez, FJ; Nebert, DW; Tuteja, N1
Bark, DH; Greenaway, JC; Juchau, MR; Shewey, LM1
Goldstein, JA; Hodgson, E; Linko, P; Yeowell, HN1
Bast, A; Kroes, BH; Savenije-Chapel, EM1
Levin, W; Reik, LM; Ryan, DE; Thomas, PE1
Parkinson, A; Robertson, LW; Safe, SH1
Kimura, R; Watanabe, K; Yoshizawa, I1
Haniu, M; Levin, W; Ryan, DE; Shively, JE1
Jollow, DJ; Longacre, S; Price, V; Roberts, S; Smith, C1
Batt, AM; Martin, N; Siest, G1
Altieri, M; Chen, YT; Ikeda, T; Nakamura, M; Nebert, DW; Negishi, M; Tukey, RH1
Delaforge, M; Ioannides, C; Parke, DV1
Levin, W; Ryan, DE; Thomas, PE; Vlasuk, GP; Walz, FG1
Delaforge, M; Ioannides, C; Parke, DV; Phillipson, CE1
Bridges, JW; Fennell, TR; Sweatman, BC1
Castell, JV; Donato, MT; Gómez-Lechón, MJ1
George, SG; Leaver, MJ; Pirrit, L1
Nemoto, N; Sakurai, J1
Law, MY; Moody, DE; Slawson, MH1
Chen, TT; Lipsky, MM; Råbergh, CM; Vrolijk, NH1
Badger, TM; Hakkak, R; Ronis, MJ; Rowlands, JC1

Reviews

1 review(s) available for 3-methylcholanthrene and safrole

ArticleYear
Pharmacokinetic considerations in toxicity testing.
    Drug metabolism reviews, 1982, Volume: 13, Issue:6

    Topics: Acetaminophen; Animals; Cricetinae; Drug Interactions; Kinetics; Liver; Methylcholanthrene; Pharmaceutical Preparations; Rats; Receptors, Drug; Safrole; Toxicology

1982

Other Studies

44 other study(ies) available for 3-methylcholanthrene and safrole

ArticleYear
Multiple patterns of induction of rat liver microsomal mono-oxygenases and other polypeptides by xenobiotics [proceedings].
    Biochemical Society transactions, 1979, Volume: 7, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Ethanol; Female; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone; Rats; Safrole

1979
Multiplicity of induction patterns of rat liver microsomal mono-oxygenases and other polypeptides produced by administration of various xenobiotics.
    The Biochemical journal, 1979, Aug-15, Volume: 182, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethanol; Female; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Peptide Biosynthesis; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Safrole

1979
Interaction of isosafrole in vivo with rat hepatic microsomal cytochrome P-450 following treatment with phenobarbitone or 20-methylcholanthrene.
    Biochemical pharmacology, 1979, Apr-15, Volume: 28, Issue:8

    Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Drug Interactions; Enzyme Induction; Isomerism; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Safrole

1979
A novel haemoprotein induced by isosafrole pretreatment in the rat.
    Biochemical and biophysical research communications, 1978, Jan-13, Volume: 80, Issue:1

    Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Isomerism; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Safrole; Spectrum Analysis

1978
The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes.
    The Biochemical journal, 1976, Mar-15, Volume: 154, Issue:3

    Topics: Acetone; Aniline Hydroxylase; Animals; Benzopyrene Hydroxylase; Benzopyrenes; Catechol Oxidase; Cricetinae; Cytochromes; Dactinomycin; Dioxoles; Male; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nikethamide; Phenobarbital; Rats; Safrole

1976
The effect of age on inducibility of various types of rat liver cytochrome P-450.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:5

    Topics: Aging; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Liver; Male; Methylcholanthrene; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred BN; RNA, Messenger; Safrole

1992
Effects of arsenite on hepatic mixed-function oxidase activity in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:5

    Topics: Animals; Arsenic; Arsenites; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Wistar; Safrole

1992
Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism.
    Journal of chromatography, 1992, Mar-13, Volume: 575, Issue:1

    Topics: Acetone; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cimetidine; Dexamethasone; Diazepam; Enzyme Induction; Female; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Safrole; Sex Characteristics; Stereoisomerism; Sulfaphenazole

1992
Differential cumene hydroperoxide sensitivity of cytochrome P-450 enzymes IA1 and IIB1 determined by their way of membrane incorporation.
    Biochimica et biophysica acta, 1992, Sep-15, Volume: 1117, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Electrophoresis, Polyacrylamide Gel; Kinetics; Lipid Peroxidation; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Steroid Hydroxylases

1992
Metabolism in vitro of 3,4,3',4'- and 2,5,2',5'-tetrachlorobiphenyl by rat liver microsomes and highly purified cytochrome P-450.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:5

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Safrole; Sulfhydryl Compounds

1991
High affinity phenacetin O-deethylase is catalysed specifically by cytochrome P450d (P450IA2) in the liver of the rat.
    Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cyclohexanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Oxidoreductases; Phenacetin; Rats; Rats, Inbred Strains; Safrole; Substrate Specificity

1990
The inducibility and catalytic activity of cytochromes P450c (P450IA1) and P450d (P450IA2) in rat tissues.
    Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxidoreductases; Rats; Rats, Inbred Strains; Safrole; Tissue Distribution

1990
Hepatic microsomal N-hydroxylation of adenine to 6-N-hydroxylaminopurine.
    Biochemical pharmacology, 1990, Mar-01, Volume: 39, Issue:5

    Topics: Adenine; Animals; Catalase; Chromatography, High Pressure Liquid; Female; Hydroxylation; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains; Safrole; Superoxide Dismutase

1990
Effects of cytochrome P-450 monooxygenase inducers on mouse hepatic microsomal metabolism of testosterone and alkoxyresorufins.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Activation; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Oxazines; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Pyridines; Safrole; Testosterone

1990
The effects of selective cytochrome P-450 inducing agents on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in rats.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Trimethadione

1990
Qualitative and quantitative differences in the induction and inhibition of hepatic benzo[a]pyrene metabolism in the rat and hamster.
    Biochemical pharmacology, 1988, Apr-15, Volume: 37, Issue:8

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole; Species Specificity

1988
Albendazole sulfonation by rat liver cytochrome P-450c.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Albendazole; Animals; Anthelmintics; Aroclors; Benzimidazoles; Biotransformation; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains; Safrole

1988
Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:11

    Topics: Animals; Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Hexobarbital; Imidazoles; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Rats; Rats, Inbred Strains; Safrole

1987
Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.
    Molecular pharmacology, 1986, Volume: 29, Issue:4

    Topics: Adult; Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Cytochrome P-450 Enzyme System; Dioxoles; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Humans; Immunosorbent Techniques; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Rats; Safrole

1986
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole

1986
Induction of a high spin form of microsomal cytochrome P-448 in rat liver by 4-aminoazobenzene derivatives.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Animals; Azo Compounds; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochromes; Dose-Response Relationship, Drug; Male; Methylcholanthrene; Microsomes, Liver; p-Aminoazobenzene; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole

1986
The microsomal metabolism of pentachlorophenol and its covalent binding to protein and DNA.
    Chemico-biological interactions, 1986, Oct-15, Volume: 60, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chlorophenols; DNA; Female; Hexachlorobenzene; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Pentachlorophenol; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Safrole

1986
Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 gene.
    European journal of biochemistry, 1985, Sep-16, Volume: 151, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Carcinogens; Cell Line; Cloning, Molecular; Cytochrome P-450 Enzyme System; Diazonium Compounds; DNA; Electrophoresis, Agar Gel; Genes; Humans; Hydrolases; Lymphocytes; Macaca fascicularis; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Polycyclic Compounds; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; Safrole

1985
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:4

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Estradiol; Ethanol; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Placenta; Polychlorinated Dibenzodioxins; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid Hydroxylases

1985
Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.
    Developmental biology, 1985, Volume: 112, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromosome Mapping; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dioxins; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Induction; Female; Gene Expression Regulation; Genes; Liver; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Pregnancy; Safrole; Steroid Hydroxylases

1985
Generation of reactive dysmorphogenic intermediates by rat embryos in culture: effects of cytochrome P-450 inducers.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:3 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Aroclors; Biotransformation; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Embryo, Mammalian; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains; Safrole

1985
Induction of specific cytochrome P-450 isozymes by methylenedioxyphenyl compounds and antagonism by 3-methylcholanthrene.
    Archives of biochemistry and biophysics, 1985, Volume: 243, Issue:2

    Topics: Animals; Cell-Free System; Collodion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxoles; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunochemistry; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Polyribosomes; Radioimmunoassay; Rats; Rats, Inbred Strains; Safrole; Spectrophotometry

1985
Inhibition of mono-oxygenase and oxidase activity of rat-hepatic cytochrome P-450 by H2-receptor blockers.
    Xenobiotica; the fate of foreign compounds in biological systems, 1984, Volume: 14, Issue:5

    Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Imidazoles; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Ranitidine; Rats; Rats, Inbred Strains; Safrole

1984
Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics.
    The Journal of biological chemistry, 1983, Apr-10, Volume: 258, Issue:7

    Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Immune Sera; Immunodiffusion; Isomerism; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Radioimmunoassay; Rats; Safrole

1983
Induction of rat hepatic microsomal cytochrome P-450 by 2,3',4,4',5,5'-hexachlorobiphenyl.
    Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14

    Topics: Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Spectrophotometry

1983
An induction effect of phenobarbital on rat liver microsomal 4-hydroxylation of estradiol 17-sulfate.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:9

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Hydroxylation; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Safrole

1984
Structures of cysteine-containing peptides in isosafrole-inducible rat hepatic microsomal cytochrome P-450d: sequence homology with 3-methylcholanthrene-induced cytochrome P-450c.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14

    Topics: Amino Acid Sequence; Animals; Cysteine; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Peptide Fragments; Rats; Safrole; Trypsin

1984
Induction of group-1 and group-2 UDP-glucuronosyltransferase in microsomes from the livers of C57 Bl/6 mice.
    Toxicology letters, 1981, Volume: 9, Issue:4

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Glucuronosyltransferase; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Safrole; Substrate Specificity

1981
Characterization of cytochrome P2-450 (20-S) mRNA. Association with the P1-450 genomic gene and differential response to the inducers 3-methylcholanthrene and isosafrole.
    European journal of biochemistry, 1983, Jul-15, Volume: 134, Issue:1

    Topics: Animals; Cloning, Molecular; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Female; Gene Expression Regulation; Kidney; Liver; Male; Methylcholanthrene; Mice; Nucleic Acid Hybridization; Phenobarbital; Polychlorinated Dibenzodioxins; RNA, Messenger; Safrole

1983
Ligand binding of safrole to cytochrome P-450.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 4

    Topics: Animals; Binding, Competitive; Cytochrome P-450 Enzyme System; Dioxoles; In Vitro Techniques; Ligands; Male; Methylcholanthrene; Microsomes, Liver; Protein Binding; Rats; Safrole

1980
Polypeptide patterns of hepatic microsomes from Long-Evans rats treated with different xenobiotics.
    Biochemistry, 1982, Nov-23, Volume: 21, Issue:24

    Topics: Animals; Aroclors; Chlordan; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Isomerism; Male; Methylcholanthrene; Microsomes, Liver; Peptide Biosynthesis; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole; Stilbenes

1982
Studies on the substrate-binding sites of liver microsomal cytochrome P-448.
    The Biochemical journal, 1982, Oct-01, Volume: 207, Issue:1

    Topics: Animals; Benzphetamine; Binding Sites; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Ellipticines; Fluorenes; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Spectrophotometry; Substrate Specificity

1982
The induction of hepatic cytochrome P-450 in C57 BL/10 and DBA/2 mice by isosafrole and piperonyl butoxide. A comparative study with other inducing agents.
    Chemico-biological interactions, 1980, Volume: 31, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Isomerism; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Safrole

1980
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Adult; Aged; Cells, Cultured; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Ethanol; Female; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Nitrophenols; Oxazines; Oxidation-Reduction; Phenobarbital; Safrole; Substrate Specificity; Testosterone

1995
Cytochrome P450 1A1 cDNA from plaice (Pleuronectes platessa) and induction of P450 1A1 mRNA in various tissues by 3-methylcholanthrene and isosafrole.
    Molecular marine biology and biotechnology, 1993, Volume: 2, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Flounder; Humans; Liver; Methylcholanthrene; Molecular Sequence Data; Organ Specificity; Restriction Mapping; RNA, Messenger; Safrole; Sequence Homology, Amino Acid

1993
Cell-density-dependent expression of Cyp1a2 gene in monolayer-cultured adult mouse hepatocytes.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:3

    Topics: Animals; Blotting, Northern; Cell Count; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Liver; Methylcholanthrene; Mice; Mice, Inbred C57BL; Oxidoreductases; Polychlorinated Dibenzodioxins; RNA, Messenger; Safrole; Time Factors

1993
Selective involvement of cytochrome P450 2D subfamily in in vivo 4-hydroxylation of amphetamine in rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:3

    Topics: Amphetamine; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethanol; Hydroxylation; Isoenzymes; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; p-Hydroxyamphetamine; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Safrole

2000
Differential expression of two CYP1A genes in rainbow trout (Oncorhynchys mykiss).
    Toxicology and applied pharmacology, 2000, Jun-15, Volume: 165, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Blotting, Northern; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Induction; Female; Gene Expression Regulation; Liver; Male; Methylcholanthrene; Oncorhynchus mykiss; Polychlorinated Dibenzodioxins; Polymerase Chain Reaction; RNA, Messenger; Safrole; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid

2000
Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood.
    The Journal of nutrition, 2001, Volume: 131, Issue:4

    Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Caseins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytosol; Dietary Proteins; Enzyme Induction; Female; Fertilization; Liver; Male; Methylcholanthrene; Milk Proteins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Safrole; Soybean Proteins; Whey Proteins

2001