3-methylcholanthrene and pregnenolone

3-methylcholanthrene has been researched along with pregnenolone in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hildebraunt, AG; Roots, I1
Conney, AH; Jerina, DM; Levin, W; Tomaszewski, JE1
Cameron, RG; Farber, E; Joly, JG; Murray, RK; Sharma, RN1
Estabrook, RW; Kawano, S; Werringloer, J1
Gangolli, SD; Hodgson, RA; Lake, BG; Lloyd, AG; Longland, RC; Severn, BJ1
Jensen, NM; Kumaki, K; Nebert, DW; Shire, JG1
Oesch, F2
Boyd, GS; Brown, MJ1
Conney, AH; Kuntzman, R; Lu, AY; Somogyi, A; West, S1
Juchau, MR1
Hrycay, EC; O'Brien, PJ1
Berg, A; Gustafsson, JA1
Blascheck, JA; Garg, BD; Kovacs, K1
Gustafsson, JA; Ingelman-Sundberg, M; Nilsen, OG; Toftgård, R1
Gunnarsson, PO; Seidegård, J; Tuvesson, H1

Other Studies

16 other study(ies) available for 3-methylcholanthrene and pregnenolone

ArticleYear
Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes.
    Archives of biochemistry and biophysics, 1975, Volume: 171, Issue:2

    Topics: Animals; Azides; Ethanol; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Pregnenolone; Rats; Scopoletin

1975
A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system.
    Archives of biochemistry and biophysics, 1976, Volume: 176, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Membranes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone; Rats; Tritium; Zoxazolamine

1976
Multiple patterns of induction of rat liver microsomal mono-oxygenases and other polypeptides by xenobiotics [proceedings].
    Biochemical Society transactions, 1979, Volume: 7, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Ethanol; Female; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone; Rats; Safrole

1979
Spin state transitions of liver microsomal cytochrome P-450.
    Acta biologica et medica Germanica, 1979, Volume: 38, Issue:2-3

    Topics: Animals; Camphor; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pregnenolone; Protein Binding; Rats; Spectrophotometry

1979
The effect of some inducers of hepatic xenobiotic-metabolizing enzymes on the urinary excretion of D-glucuronic acid metabolites in the rat.
    Biochemical Society transactions, 1975, Volume: 3, Issue:1

    Topics: Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine-N-Demethylase; Glucuronates; Glucuronosyltransferase; Hymecromone; Insecticides; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone; Rats; Time Factors; Toluene

1975
Genetic differences in induction of cytosol reduced-NAD(P):menadione oxidoreductase and microsomal aryl hydrocarbon hydroxylase in the mouse.
    The Journal of biological chemistry, 1977, Jan-10, Volume: 252, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Crosses, Genetic; Cytosol; Enzyme Induction; Flavonoids; Genetic Variation; Kinetics; Liver; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; NADH, NADPH Oxidoreductases; Nitriles; Phenobarbital; Polychlorinated Dibenzodioxins; Pregnenolone; Quinone Reductases; Species Specificity

1977
Transplacental control of epoxide hydratase and its relationship to the control of microsomal monooxygenase.
    FEBS letters, 1975, May-01, Volume: 53, Issue:2

    Topics: Animals; Benzopyrenes; Epoxide Hydrolases; Female; Hydro-Lyases; Liver; Maternal-Fetal Exchange; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Placenta; Pregnancy; Pregnenolone; Rats; Time Factors

1975
Differential control of rat microsomal "aryl hydrocarbon" monooxygenase and epoxide hydratase.
    The Journal of biological chemistry, 1976, Jan-10, Volume: 251, Issue:1

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Epoxide Hydrolases; Female; Fetus; Hydro-Lyases; Liver; Methylcholanthrene; Microsomes, Liver; Mutagens; Nitriles; Phenobarbital; Pregnancy; Pregnenolone; Rats

1976
The specificity of the rat-liver cholesterol 7alpha-hydroxylase.
    European journal of biochemistry, 1974, May-02, Volume: 44, Issue:1

    Topics: Alcohol Oxidoreductases; Aminopyrine N-Demethylase; Androstenols; Animals; Cholesterol; Cholestyramine Resin; Cycloheximide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Phenobarbital; Pregnenolone; Protein Binding; Rats; Time Factors

1974
Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Spectrophotometry

1972
Human placental hydroxylation of 3,4-benzpyrene during early gestation and at term.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3

    Topics: 17-Ketosteroids; Androstanes; Animals; Benzopyrenes; Cholesterol; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Fluorometry; Humans; Kinetics; Labor, Obstetric; Liver; Methylcholanthrene; Methyltestosterone; Mixed Function Oxygenases; NADP; Placenta; Pregnancy; Pregnenolone; Progesterone; Rats; Smoking; Testosterone

1971
Cytochrome P-450 as a microsomal peroxidase in steroid hydroperoxide reduction.
    Archives of biochemistry and biophysics, 1972, Volume: 153, Issue:2

    Topics: Adrenal Glands; Aniline Compounds; Animals; Cattle; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Hydroxylation; Hydroxyprogesterones; Kinetics; Ligands; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxidation-Reduction; Peroxidases; Peroxides; Phenobarbital; Pregnenolone; Progesterone; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids

1972
Regulation of hydroxylation of 5 alpha-androstane-3 beta, 17 beta-diol in liver microsomes from male and female rats.
    The Journal of biological chemistry, 1973, Sep-25, Volume: 248, Issue:18

    Topics: Androstanes; Animals; Carbon Isotopes; Carbon Monoxide; Castration; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Dihydrotestosterone; Estradiol; Female; Hydroxylation; Hydroxysteroids; Male; Mass Spectrometry; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnenolone; Rats; Sex Factors; Testis; Testosterone; Time Factors

1973
A comparative ultrastructural study on drug-induced proliferation of smooth-surfaced endoplasmic reticulum in hepatocytes.
    The Tohoku journal of experimental medicine, 1971, Volume: 104, Issue:3

    Topics: Animals; Endoplasmic Reticulum; Female; Liver; Methylcholanthrene; Microscopy, Electron; Organoids; Phenobarbital; Pregnenolone; Rats; Spironolactone

1971
Correlation between changes in enzymatic activities and induction of different forms of rat liver microsomal cytochrome P-450 after phenobarbital-, 3-methylcholanthrene- and 16 alpha-cyanopregnenolone treatment.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:5

    Topics: Androstane-3,17-diol; Androstenedione; Animals; Benzopyrenes; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Organ Size; Phenobarbital; Pregnenolone; Rats

1980
Metabolism of tauromustine in liver and lung microsomes from various species.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes; Dogs; Female; Humans; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Nitrosourea Compounds; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Rats, Sprague-Dawley; Species Specificity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Taurine; Testosterone

1999