3-methylcholanthrene has been researched along with phenacetin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Hinson, JA; Mitchell, JR; Nelson, SD | 1 |
| Conney, AH; Kaplan, SA; Kuntzman, R; Pantuck, EJ | 1 |
| Gorman, N; Lambrecht, RW; Sinclair, JF; Sinclair, PR | 1 |
| Boobis, AR; Davies, DS; Edwards, RJ; Levin, W; Sesardic, D; Thomas, PE | 1 |
| de Vries, J; Redegeld, FA; van Bree, L | 1 |
| Fischbach, T; Lenk, W | 1 |
| Cavallito, J; Loh, A; Welch, RM | 1 |
| Cinti, DL; Kraschnitz, R; Moldeus, P; Orrenius, S; Schenkman, JB | 1 |
| Nery, R | 1 |
| Orrenius, S; Schenkman, JB; Von Bahr, C; Wilson, B | 1 |
| Burns, JJ; Conney, AH; Koster, R; Sansur, M; Soroko, F | 1 |
| Burns, JJ; Conney, AH; Welch, RM | 1 |
| Klippert, PJ; Littel, RJ; Noordhoek, J | 1 |
| Borm, PJ; Frankhuijzen-Sierevogel, A; Noordhoek, J | 1 |
| Borm, P; Klippert, P; Noordhoek, J | 1 |
17 other study(ies) available for 3-methylcholanthrene and phenacetin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Studies on the microsomal formation of arylating metabolites of acetaminophen and phenacetin.
Topics: Acetaminophen; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Glutathione; In Vitro Techniques; Kinetics; Male; Mass Spectrometry; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxygen Isotopes; Phenacetin; Phenobarbital | 1977 |
Phenacetin metabolism: effect of hydrocarbons and cigarette smoking.
Topics: Animals; Benzopyrenes; Dealkylation; Drug Interactions; Humans; In Vitro Techniques; Intestines; Male; Methylcholanthrene; Phenacetin; Polycyclic Compounds; Rats; Smoking | 1977 |
Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2.
Topics: Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Ketoconazole; Kinetics; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Quinolines; Uroporphyrinogens | 1992 |
High affinity phenacetin O-deethylase is catalysed specifically by cytochrome P450d (P450IA2) in the liver of the rat.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cyclohexanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Oxidoreductases; Phenacetin; Rats; Rats, Inbred Strains; Safrole; Substrate Specificity | 1990 |
The 3-methylcholanthrene-mimetic effect of 4,4'-dichlorobiphenyl-treatment on phenacetin-induced hepatic glutathione depletion and liver microsomal phenacetin O-deethylation in rats.
Topics: Acetaminophen; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Glutathione; Liver; Male; Methylcholanthrene; Oxidoreductases; Phenacetin; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains | 1986 |
Additional routes in the metabolism of phenacetin.
Topics: Acetylation; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenacetin; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains | 1985 |
Effect of exposure to cigarette smoke on the metabolism of benzo(a)pyrene and acetophenetidin by lung and intestine of rats.
Topics: Animals; Benzopyrenes; Carbon Isotopes; Dactinomycin; Enzyme Induction; Female; Hydrocarbons; Intestinal Mucosa; Intestines; Kinetics; Liver; Lung; Male; Methylcholanthrene; Mixed Function Oxygenases; Nicotiana; Phenacetin; Plants, Toxic; Pregnancy; Puromycin; Rats; Smoking; Time Factors | 1972 |
The nature of the reverse type I (modified type II) spectral change in liver microsomes.
Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Synergism; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Rabbits; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet | 1972 |
The binding of radioactive label from labelled phenacetin and related compounds to rat tissues in vivo and to nucleic acids and bovine plasma albumin in vitro.
Topics: Animals; Binding Sites; Carbon Isotopes; DNA; In Vitro Techniques; Intestinal Mucosa; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Nucleic Acids; Phenacetin; Protein Binding; Rats; RNA; Serum Albumin, Bovine; Spleen; Tritium; Urinary Bladder | 1971 |
The significance of drug-induced spectral changes in liver microsomal fraction.
Topics: Animals; Binding Sites; Cytochromes; Hexobarbital; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Nortriptyline; Oxidoreductases; Phenacetin; Rabbits; Spectrum Analysis | 1971 |
Enzyme induction and inhibition in studies on the pharmacological actions of acetophenetidin.
Topics: Animals; Fever; In Vitro Techniques; Liver; Methylcholanthrene; Phenacetin; Proadifen; Rats | 1966 |
The metabolism of acetophenetidin and N-acetyl-p-aminophenol in the cat.
Topics: Acetaminophen; Animals; Cats; Chromatography; Dogs; Glucuronates; Liver; Male; Methemoglobinemia; Methylcholanthrene; Phenacetin; Rats | 1966 |
In vivo O-de-ethylation of phenacetin in 3-methylcholanthrene-pretreated rats: gut wall and liver first-pass metabolism.
Topics: Acetaminophen; Animals; Biological Availability; Intestinal Absorption; Intestinal Mucosa; Kinetics; Liver; Male; Methylcholanthrene; Phenacetin; Rats; Rats, Inbred Strains | 1983 |
Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes. The effect of induction with 3-methylcholanthrene and inhibition with alpha-naphthoflavone.
Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Flavonoids; Humans; Intestinal Mucosa; Kinetics; Male; Methylcholanthrene; Mice; Microsomes; Phenacetin; Rats; Rats, Inbred Strains | 1983 |
Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data--correlation with in vivo data using mucosal blood flow.
Topics: Animals; Dealkylation; Intestinal Mucosa; Kinetics; Male; Methylcholanthrene; Phenacetin; Rats; Rats, Inbred Strains; Regional Blood Flow | 1982 |