3-methylcholanthrene and pentobarbital

3-methylcholanthrene has been researched along with pentobarbital in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199024 (92.31)18.7374
1990's1 (3.85)18.2507
2000's1 (3.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradshaw, JJ; Ivanetich, KM; Ziman, MR1
Fukuhara, M; Takabatake, E1
Hulshoff, A; Kostenbauder, HB; Lubawy, WC1
Banerjee, S; Conney, AH; Kuntzman, R; Levin, W; Somogyi, A1
Hanioka, N; Ishida, C; Koga, N; Saeki, HK; Yoshimura, H1
Bock, KW; Bock-Hennig, BS1
Masuda, Y; Yasoshima, M1
Bogdanffy, MS; Brown, DR; Roberts, AE; Schatz, RA1
Liem, HH; Muller-Eberhard, U; Smibert, E1
Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL1
Kato, R2
Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, S1
Kato, R; Omori, Y; Takanaka, A1
Feuer, G; Liscio, A1
Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, SB1
Jacobson, M; Kuntzman, R; Lu, AY; Sernatinger, E; West, S1
Kato, R; Oshima, T; Takayanagi, M1
Dorough, HW; Graziano, MJ; Webb, JD1
Benjamin, T; Grantham, PH; Reddy, TV; Thorgeirsson, SS; Weisburger, EK1
Kleeberg, U; Klinger, W1
Berg, IE; Chaturvedi, AK; Rao, NG1
Chan, PK; Hayes, AW; Reddy, CS1
Gelboin, HV; Guengerich, FP; Robie-Suh, K; Robinson, R1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1
Debski, B; Milner, JA1

Reviews

1 review(s) available for 3-methylcholanthrene and pentobarbital

ArticleYear
Sex-related differences in drug metabolism.
    Drug metabolism reviews, 1974, Volume: 3, Issue:1

    Topics: Aniline Compounds; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Estradiol; Female; Hexobarbital; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADH, NADPH Oxidoreductases; Oxidoreductases, N-Demethylating; Pentobarbital; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Proadifen; Rats; Sex Factors; Spectrophotometry; Spectrophotometry, Ultraviolet; Strychnine; Testosterone

1974

Other Studies

25 other study(ies) available for 3-methylcholanthrene and pentobarbital

ArticleYear
The degradation of different forms of cytochrome P-450 in vivo by fluroxene and allyl-iso-propylacetamide.
    Biochemical and biophysical research communications, 1978, Dec-14, Volume: 85, Issue:3

    Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Ethers; Heme; Male; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Proteins; Rats

1978
The effects of nitrofuran derivatives on hepatic microsomal mixed-function oxidase activity in rats.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Female; Furylfuramide; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrofurans; Organ Size; Oxidoreductases; Pentobarbital; Phenobarbital; Rats; Sleep

1977
The effect of some cigarette smoke constituents and other compounds on the metabolism of benzo(a)pyrene in rabbit lung 9000 g supernatant.
    Xenobiotica; the fate of foreign compounds in biological systems, 1978, Volume: 8, Issue:11

    Topics: Acetone; Animals; Benzopyrenes; Chlorpromazine; In Vitro Techniques; Lung; Male; Methylcholanthrene; Nicotiana; Nicotine; Pentobarbital; Plants, Toxic; Rabbits; Smoke; Subcellular Fractions

1978
Inhibition of the acute toxicity and adrenocorticolytic effect of 7,12-dimethylbenz(a)anthracene by isopropylvaleramide and allylisopropylacetamide in the rat.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Adrenal Cortex; Adrenal Glands; Allylisopropylacetamide; Amides; Animals; Barbiturates; Benz(a)Anthracenes; Benzopyrenes; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Liver; Methylcholanthrene; Pentobarbital; Phenobarbital; Proadifen; Rats; Secobarbital; Time Factors; Valerates

1975
Metabolism in vitro of 3,4,3',4'- and 2,5,2',5'-tetrachlorobiphenyl by rat liver microsomes and highly purified cytochrome P-450.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:5

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Safrole; Sulfhydryl Compounds

1991
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Induction; Female; Glucuronosyltransferase; Humans; Hydroquinones; Hymecromone; Isoenzymes; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Middle Aged; Naphthols; Pentobarbital; Phenytoin; Tumor Cells, Cultured

1987
Action of carbon tetrachloride in the reconstituted monooxygenase system using partially purified cytochrome P-450 and P-448.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:2

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Lipid Peroxides; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Pentobarbital; Rats; Rats, Inbred Strains

1987
Regioselective inhibition of benzo(a)pyrene metabolism by corticosterone in comparison with metyrapone and alpha-naphthoflavone.
    Toxicology letters, 1986, Volume: 31, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Chromatography, High Pressure Liquid; Corticosterone; Cytochrome P-450 Enzyme System; Drug Interactions; Flavonoids; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Pyridines; Rats; Rats, Inbred Strains

1986
Studies on the induction of serum hemopexin by pentobarbital and polycyclic hydrocarbons.
    Biochemical pharmacology, 1972, Jun-15, Volume: 21, Issue:12

    Topics: Animals; Benzopyrenes; Beta-Globulins; Chloramphenicol; Cycloheximide; Drug Tolerance; Heme; Hemopexin; Immunodiffusion; Male; Methylcholanthrene; Pentobarbital; Polycyclic Compounds; Rabbits; Starvation; Time Factors

1972
Lipid peroxidation and the degradation of cytochrome P-450 heme.
    Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:2

    Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium

1973
The role of cytochrome P-450 and P-448 in drug and steroid hydroxylations.
    Annals of the New York Academy of Sciences, 1973, Volume: 212

    Topics: Age Factors; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hydroxylation; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Morphine Derivatives; Pentobarbital; Phenobarbital; Piperazines; Rats; Testosterone

1973
Factors affecting the toxicity and metabolism of OMPA (octamethylpyrophosphoramide) in rats.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:4

    Topics: Age Factors; Animals; Butylene Glycols; Chlorpromazine; Cholinesterase Inhibitors; Cholinesterases; Diphosphates; Ethionine; Female; Glutethimide; Insecticides; Liver; Male; Meprobamate; Methylcholanthrene; Microsomes; Pentobarbital; Phenobarbital; Proadifen; Rats

1967
Effect of drugs on hepatic drug metabolism in the fetus and newborn.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:1

    Topics: Animals; Animals, Newborn; Coumarins; Female; Fetus; Glucose-6-Phosphatase; Liver; Maternal-Fetal Exchange; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Phenobarbital; Pregnancy; Pregnancy, Animal; Rats; Sleep; Transferases

1970
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VI. Different substrate specificities of the cytochrome P450 fractions from control and phenobarbital-treated rats.
    The Journal of biological chemistry, 1973, Jan-25, Volume: 248, Issue:2

    Topics: Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Flavonoids; Hemeproteins; Hydroxylation; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital; Piperazines; Proadifen; Rats; Structure-Activity Relationship; Testosterone

1973
The effect of altering liver microsomal co-binding hemoprotein composition on pentobarbital-induced anesthesia.
    Chemico-biological interactions, 1972, Volume: 5, Issue:3

    Topics: Animals; Brain Chemistry; Carbon Isotopes; Cell Fractionation; Chromatography, Paper; Cytochromes; Hydroxylation; Male; Methods; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Sleep

1972
Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Brain; Brain Chemistry; Cytochromes; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Nitrobenzenes; Pentobarbital; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Triazoles; Zoxazolamine

1967
Differences in the oxidative metabolism of drugs by liver microsomes.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine

1969
In vitro hepatic enzyme activity in rats exposed nose-only to cigarette smoke.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:5

    Topics: Animals; Body Weight; Carboxyhemoglobin; Glutathione; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nicotiana; Organ Size; Pentobarbital; Phenobarbital; Plants, Toxic; Rats; Rats, Inbred Strains; Smoke

1984
Mutagenicity of urine from rats after administration of 2,4-diaminoanisole: the effect of microsomal enzyme inducers.
    Mutation research, 1980, Volume: 79, Issue:4

    Topics: Animals; Anisoles; Benzoflavones; beta-Naphthoflavone; Biotransformation; Male; Methylcholanthrene; Mutagenicity Tests; Mutagens; Pentobarbital; Phenylenediamines; Polychlorinated Dibenzodioxins; Rats; Salmonella typhimurium

1980
Age course and inducibility of dimethylnitrosamine N-demethylation in rat liver.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:7-8

    Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Kinetics; Liver; Male; Methylcholanthrene; Oxidoreductases, N-Demethylating; Pentobarbital; Rats; Rats, Inbred Strains

1982
The role of hepatic microsomal enzymes in the modulation of phencyclidine-induced toxicity.
    Toxicology, 1981, Volume: 22, Issue:3

    Topics: Animals; Body Weight; Cysteine; Eating; Lethal Dose 50; Liver; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Pentobarbital; Phencyclidine; Phenobarbital; Proadifen

1981
Acute toxicity of penicillic acid and its interaction with pentobarbital and other compounds.
    Toxicology and applied pharmacology, 1980, Volume: 52, Issue:1

    Topics: Animals; Body Temperature; Caproates; Cysteine; Drug Interactions; Lethal Dose 50; Male; Maleates; Methylcholanthrene; Mice; Penicillic Acid; Pentobarbital; Proadifen; Sleep; Time Factors

1980
Aryl hydrocarbon hydroxylase is inhibited by antibody to rat liver cytochrome P-450.
    Science (New York, N.Y.), 1980, May-30, Volume: 208, Issue:4447

    Topics: Animals; Antigen-Antibody Reactions; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Lymphocytes; Methylcholanthrene; Monocytes; Pentobarbital; Rats

1980
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine

1965
Dietary selenium supplementation prolongs pentobarbital induced hypnosis.
    The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:9

    Topics: Age Factors; Amitrole; Animals; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione Peroxidase; Hypnosis, Anesthetic; Hypnotics and Sedatives; Liver; Male; Methylcholanthrene; Pentobarbital; Rats; Rats, Sprague-Dawley; Selenium

2004