Compounds > 3-methylcholanthrene

3-methylcholanthrene and omeprazole

3-methylcholanthrene has been researched along with omeprazole in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bories, P; Daujat, M; Diaz, D; Fabre, I; Maurel, P; Michel, H; Saint Aubert, B1
Li, AP; Masubuchi, N; Okazaki, O1
Albrecht, W; Arnold, PJ; Fischer, J; Gerlach, J; Liu, L; Neuhaus, P; Nussler, AK; Wang, A; Yuan, J; Zeilinger, K1
Delescluse, C; Ledirac, N; Lemaire, G; Lesca, P; Pralavorio, M; Rahmani, R1
Bae, SK; Lee, DY; Lee, MG; Shin, HS1
Caguyong, M; Cheng, O; Coe, KJ; Dai, X; He, Y; Nelson, SD; Roberts, CJ; Slatter, JG; Ulrich, RG1
Dial, S; Guo, L; Ning, B; Sun, Y; Wang, J; Yang, J1
Dvorak, Z; Novotna, A; Pavek, P1
Aikawa, K; Ichikawa, H; Kamada, N; Matsunaga, T; Nakamura, K; Ohmori, S; Sasaki, K; Tsuchiya, H1

Other Studies

9 other study(ies) available for 3-methylcholanthrene and omeprazole

ArticleYear
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.
    Gastroenterology, 1990, Volume: 99, Issue:3

    Topics: Aged; Benzoflavones; beta-Naphthoflavone; Blotting, Northern; Blotting, Western; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life; Humans; In Vitro Techniques; Liver; Male; Methylcholanthrene; Middle Aged; Omeprazole; Oxygenases; Rifampin; RNA, Messenger

1990
An evaluation of the cytochrome P450 induction potential of pantoprazole in primary human hepatocytes.
    Chemico-biological interactions, 1998, Jul-03, Volume: 114, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzimidazoles; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Lansoprazole; Liver; Male; Methylcholanthrene; Middle Aged; Omeprazole; Pantoprazole; Rifampin; Steroid Hydroxylases; Structure-Activity Relationship; Sulfoxides

1998
The suitability of hepatocyte culture models to study various aspects of drug metabolism.
    ALTEX, 2001, Volume: 18, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bioreactors; Cell Culture Techniques; Cell Separation; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytosol; Diclofenac; Hepatocytes; Kinetics; L-Lactate Dehydrogenase; Male; Methylcholanthrene; Mitochondria, Liver; Models, Biological; Omeprazole; Rats; Rats, Sprague-Dawley; Serum Albumin

2001
The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes.
    Life sciences, 2004, Mar-19, Volume: 74, Issue:18

    Topics: Animals; Benz(a)Anthracenes; Benzoquinones; Cells, Cultured; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; Hepatocytes; Lactams, Macrocyclic; Male; Methylcholanthrene; Omeprazole; Polychlorinated Dibenzodioxins; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Rifabutin; RNA, Messenger; Thiabendazole

2004
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous omeprazole in rats.
    Biopharmaceutics & drug disposition, 2006, Volume: 27, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Injections, Intravenous; Male; Methylcholanthrene; Microsomes, Liver; Omeprazole; Proadifen; Rats; Rats, Sprague-Dawley

2006
Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Androgen Antagonists; Animals; Aryl Hydrocarbon Hydroxylases; Cluster Analysis; Constitutive Androstane Receptor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flutamide; Gene Expression Profiling; Hypertrophy; Liver; Methylcholanthrene; Oligonucleotide Array Sequence Analysis; Omeprazole; Pregnane X Receptor; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors

2006
Systematic and simultaneous gene profiling of 84 drug-metabolizing genes in primary human hepatocytes.
    Journal of biomolecular screening, 2008, Volume: 13, Issue:3

    Topics: Brain; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation; Hepatocytes; Humans; Inactivation, Metabolic; Methylcholanthrene; Omeprazole; Polymerase Chain Reaction; Principal Component Analysis; Rifampin; RNA

2008
Novel stably transfected gene reporter human hepatoma cell line for assessment of aryl hydrocarbon receptor transcriptional activity: construction and characterization.
    Environmental science & technology, 2011, Dec-01, Volume: 45, Issue:23

    Topics: Anthracenes; Gene Expression; Hep G2 Cells; Humans; Indoles; Luciferases; Methylcholanthrene; Omeprazole; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Transfection

2011
Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers.
    Drug metabolism and pharmacokinetics, 2012, Volume: 27, Issue:6

    Topics: Adult; Albumins; alpha-Fetoproteins; Animals; Biotransformation; Cell Differentiation; Cell Line; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Discovery; Embryonic Stem Cells; Enzyme Induction; Glucuronosyltransferase; Hepatocytes; Humans; Inactivation, Metabolic; Male; Methylcholanthrene; Mice; Middle Aged; Omeprazole; RNA, Messenger

2012