3-methylcholanthrene and morphine

3-methylcholanthrene has been researched along with morphine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's2 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mardones, J; Sánchez, E; Tampier, L1
Bock, KW; Josting, D; Ottenwälder, H; von Clausbruch, UC1
de Sandro, V; Ducrotoy, G; Kriszt, W; Lett, E; Richert, L1
Hanioka, N; Hoshikawa, Y; Mitsui, T; Oguri, K; Yoshimura, H1
Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR1
Gillette, JR; Stripp, B1
Gillete, JR; Hamrick, ME; Stripp, B1
Sladek, NE1
Alvares, AP; Mannering, GJ1
Mannering, GJ; Sladek, NE2
Furner, RL; Gram, TE; Stitzel, RE1
Correia, MA; Soliven, E; Wong, JS1
Finnen, MJ; Hassall, KA1
Bock, KW; Lilienblum, W; Pfeil, H1
Gregus, Z; Klaassen, CD; Thompson, TN; Watkins, JB1

Other Studies

16 other study(ies) available for 3-methylcholanthrene and morphine

ArticleYear
Receptors for morphine and opioids.
    General pharmacology, 1976, Volume: 7, Issue:2-3

    Topics: Age Factors; Animals; Dealkylation; Glucuronosyltransferase; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Nalorphine; Nitrophenols; Phenobarbital; Rats; Receptors, Opioid; Time Factors

1976
Separation and partial purification of two differentially inducible UDP-glucuronyltransferases from rat liver.
    Biochemical pharmacology, 1977, Jun-01, Volume: 26, Issue:11

    Topics: Animals; Enzyme Induction; Glucuronosyltransferase; In Vitro Techniques; Methods; Methylcholanthrene; Microsomes, Liver; Morphine; Naphthols; Phenobarbital; Rats

1977
Optimal detergent activation of rat liver microsomal UDP-glucuronosyl transferases toward morphine and 1-naphthol: contribution to induction and latency studies.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: Animals; Detergents; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Naphthols; Phenobarbital; Rats; Rats, Inbred Strains

1992
Species difference in codeine uridine diphosphate-glucuronyltransferase activity of liver microsomes.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:11

    Topics: Animals; Biphenyl Compounds; Codeine; Enzyme Induction; Glucuronosyltransferase; Guinea Pigs; In Vitro Techniques; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Nitrophenols; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Substrate Specificity

1990
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone

1986
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:10

    Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone

1972
Effect of 3-methylcholanthrene induction on the carbon tetrachloride-induced changes in rat hepatic microsomal enzyme system.
    Biochemical pharmacology, 1972, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Benzopyrenes; Carbon Tetrachloride Poisoning; Cytochromes; Enzyme Induction; Heme; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Morphine; Rats

1972
Therapeutic efficacy of cyclophosphamide as a function of its metabolism.
    Cancer research, 1972, Volume: 32, Issue:3

    Topics: Acetamides; Animals; Carcinoma 256, Walker; Cobalt; Cyclophosphamide; Cytochromes; Female; In Vitro Techniques; Kinetics; Leukocyte Count; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Rats; Sodium Chloride; Sulfides

1972
Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes.
    Molecular pharmacology, 1970, Volume: 6, Issue:3

    Topics: Alkylation; Aniline Compounds; Animals; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Stereoisomerism

1970
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates

1969
The influence of age, sex and drug treatment on microsomal drug metabolism in four rat strains.
    Biochemical pharmacology, 1969, Volume: 18, Issue:7

    Topics: Age Factors; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphine; Phenobarbital; Proteins; Rabbits; Rats; Sex Factors; Species Specificity

1969
Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats.
    Biochemical and biophysical research communications, 1966, Sep-08, Volume: 24, Issue:5

    Topics: Animals; Cyanides; Cytochromes; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes; Morphine; Phenobarbital; Rats; Spectrophotometry; Transferases

1966
Morphine metabolism revisited: I. Metabolic activation of morphine to a reactive species in rats.
    Chemico-biological interactions, 1984, Volume: 49, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biotransformation; Cytochrome P-450 Enzyme System; Dihydromorphine; Enzyme Induction; Glutathione; Liver; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1984
Effects of hypophysectomy on sex differences in the induction and depression of hepatic drug-metabolizing enzymes in the rat.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1

    Topics: Aniline Compounds; Animals; Chromatography, Gas; Epoxy Compounds; Ethylmorphine; Female; Hypophysectomy; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Rats; Rats, Inbred Strains; Sex Characteristics

1984
Functional heterogeneity of UDP-glucuronosyltransferase activities in C57BL/6 and DBA/2 mice.
    Biochemical pharmacology, 1982, Apr-01, Volume: 31, Issue:7

    Topics: Animals; Enzyme Induction; Glucuronosyltransferase; Intestinal Mucosa; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Morphine; Phenobarbital; Species Specificity; Substrate Specificity

1982
Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases.
    Toxicology and applied pharmacology, 1982, Volume: 64, Issue:3

    Topics: Animals; Chloramphenicol; Enzyme Induction; Glucuronates; Glucuronic Acid; Glucuronosyltransferase; In Vitro Techniques; Liver; Male; Methylcholanthrene; Morphine; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Valproic Acid

1982