3-methylcholanthrene has been researched along with heme in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (93.33) | 18.7374 |
| 1990's | 3 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradshaw, JJ; Ivanetich, KM; Kaminsky, LS; Marsh, JA | 1 |
| Bradshaw, JJ; Ivanetich, KM; Ziman, MR | 1 |
| Ebel, RE; O'keeffe, DH; Peterson, JA | 1 |
| Benko, B; Butschak, G; Jänig, GR; Maricić, S; Rein, H; Ruckpaul, K; Scheunig, G | 1 |
| Azhary, RE; Jeffery, E; Kotake, A | 1 |
| Alvares, AP; Kappas, A | 1 |
| Bell, DY; Hodgson, E | 1 |
| Burk, RF; Correia, MA | 1 |
| Bond, JA; Juchau, MR; Omiecinski, CJ | 1 |
| Hashimoto-Yutsudo, C; Imai, Y; Kitagawa, T; Kyogoku, Y; Ozaki, Y; Sato, R | 1 |
| de Matteis, F; Unseld, A | 1 |
| Hong, S; Levine, L; Polsky-Cynkin, R | 1 |
| McDonagh, AF; Schmid, R | 1 |
| Celier, C; Cresteil, T | 1 |
| Iwasa, F; Kappas, A; Sassa, S | 1 |
| Jayarama Bhat, G; Padmanaban, G | 1 |
| Bonkovsky, HL; Healey, JF; Lincoln, BC | 1 |
| Bhat, GJ; Padmanaban, G | 1 |
| Bonkovsky, HL; Healey, JF; Robinson, JM; Shedlofsky, SI; Sinclair, PR; Swim, AT | 1 |
| Liem, HH; Muller-Eberhard, U; Smibert, E | 1 |
| Levin, W; Lu, AY; Ryan, D; West, S | 1 |
| Gaylor, JL; Jefcoate, CR | 1 |
| Alvares, AP; Kappas, A; Mitani, F; Sassa, S | 1 |
| Mannering, GJ; Shoeman, DW; Vane, FM | 1 |
| Anders, MW; Maines, MD | 1 |
| Mason, JI; Schacter, BA | 1 |
| Dehlinger, PJ; Schimke, RT | 1 |
| Gillete, JR; Hamrick, ME; Stripp, B | 1 |
| Imai, Y; Siekevitz, P | 1 |
| Alvares, A; Conney, AH; Kuntzman, R; Levin, W | 1 |
| Alvares, AP; Kuntzman, R; Levin, W | 1 |
| Carroll, LA; Muller-Eberhard, U; Ross, JD | 1 |
| Gillette, JR; Greene, FE; Stripp, B | 1 |
| Kuntzman, R; Levin, W | 1 |
| Padmanaban, G | 1 |
| Faustman-Watts, E; Juchau, MR; Namkung, MJ | 1 |
| Edwards, AM; Glistak, ML; Lucas, CM; Wilson, PA | 1 |
| Omura, T; Sadano, H | 2 |
| Sawabe, Y; Shimada, T | 1 |
| Hatano, M; Iizuka, T; Ishimura, Y; Nozawa, T; Shimada, H; Shimizu, T | 1 |
| Kunze, KL; Ortiz de Montellano, PR | 1 |
| Baird, MB | 1 |
| Ashwood-Smith, MJ; Baer-Dubowska, W; Cai, Y; Ceska, O; DiGiovanni, J; Tachibana, S | 1 |
| Jones, EJ; Riddick, DS | 1 |
1 review(s) available for 3-methylcholanthrene and heme
| Article | Year |
|---|---|
The enzymatic formation of bilirubin.
Topics: Animals; Benzopyrenes; Bile Pigments; Bilirubin; Cytochrome P-450 Enzyme System; Female; Heme; Humans; Macrophages; Methylcholanthrene; Metyrapone; Microsomes; Organ Specificity; Oxidation-Reduction; Oxygenases; Phenobarbital; Placenta; Pregnancy; Proadifen | 1975 |
44 other study(ies) available for 3-methylcholanthrene and heme
| Article | Year |
|---|---|
Fluroxene (2,2,2-trifluoroethyl vinyl ether) mediated destruction of cytochrome P-450 in vitro.
Topics: Animals; Benzopyrenes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethers; Ethyl Ethers; Heme; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Time Factors | 1975 |
The degradation of different forms of cytochrome P-450 in vivo by fluroxene and allyl-iso-propylacetamide.
Topics: Acetamides; Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Ethers; Heme; Male; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Proteins; Rats | 1978 |
Studies of the unique nature of the cytochrome P-450 active site. Electron spin resonance spectroscopy as a probe of the hemin iron of cytochrome P-450: the influence of buffer composition, alcohols, and nitrogenous ligands.
Topics: Alkanesulfonates; Animals; Binding Sites; Buffers; Camphor; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Hemin; Male; Membranes; Methanol; Methylcholanthrene; Metyrapone; Microsomes, Liver; Morpholines; Phenobarbital; Pseudomonas; Rats | 1977 |
Comparison of microsomal and solubilized monooxygenases from rat and rabbit by proton magnetic relaxation.
Topics: Animals; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Iron; Kinetics; Ligands; Male; Methylcholanthrene; Microsomes, Liver; Nitric Oxide; Oxygenases; Phenobarbital; Rabbits; Rats; Solubility; Species Specificity; Temperature | 1979 |
Effects of linoleic acid hydroperoxide on the hepatic monooxygenase systems of microsomes from untreated, phenobarbital-treated, and 3-methylcholanthrene-treated rats.
Topics: Animals; Cytochrome Reductases; Drug Interactions; Glutathione; Heme; Hemeproteins; In Vitro Techniques; Linoleic Acids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Rats; Temperature; Time Factors | 1977 |
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats; Spectrophotometry | 1977 |
SDS-polyacylamide gel electrophoresis of hepatic cytochrome P-450 from normal, 3-methylcholanthrene and phenobarbital treated mice.
Topics: Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Heme; Male; Methods; Methylcholanthrene; Mice; Microsomes, Liver; Molecular Weight; Phenobarbital; Sodium Dodecyl Sulfate | 1977 |
Rapid stimulation of hepatic microsomal heme oxygenase in selenium-deficient rats. An effect of phenobarbital.
Topics: 5-Aminolevulinate Synthetase; Animals; Enzyme Induction; Heme; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Selenium | 1978 |
Stimulation by hematin of monooxygenase activity in extra-hepatic tissues from rats, rabbits and chickens.
Topics: Animals; Aorta; Aryl Hydrocarbon Hydroxylases; Chickens; Enzyme Activation; Heme; Hemin; Kidney; Kinetics; Liver; Lung; Male; Methylcholanthrene; Mixed Function Oxygenases; Organ Specificity; Rats; Testis | 1978 |
Resonance Raman studies of hepatic microsomal cytochromes P-450: evidence for strong pi basicity of the fifth ligand in the reduced and carbonyl complex forms.
Topics: Animals; Cytochrome P-450 Enzyme System; Heme; Hemeproteins; Ligands; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Protein Conformation; Rabbits; Spectrum Analysis, Raman | 1978 |
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Paralysis; Phenobarbital; Rats; Sleep; Zoxazolamine | 1978 |
The effects of hydroquinone, hematin and heme-containing proteins on prostaglandin biosynthesis by methylcholanthrene-transformed mouse BALB/3T3 fibroblasts.
Topics: Animals; Arachidonic Acids; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Glutathione; Heme; Hemeproteins; Hemin; Hemoglobins; Hydroquinones; Indomethacin; Methylcholanthrene; Mice; Mice, Inbred BALB C; Porphyrins; Prostaglandins; Stimulation, Chemical | 1976 |
Control of cytochromes P450 expression in Gunn rat liver: implication of the intracellular heme pool.
Topics: Animals; Biliverdine; Cytochrome P-450 Enzyme System; Heme; Heme Oxygenase (Decyclizing); Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Gunn; Tryptophan Oxygenase | 1991 |
delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals.
Topics: 5-Aminolevulinate Synthetase; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Half-Life; Heme; Hemin; Heptanoates; Humans; Iron; Liver Neoplasms; Methylcholanthrene; Time Factors; Tumor Cells, Cultured | 1989 |
Heme regulates cytochrome P-450 gene transcription elongation.
Topics: Animals; Cell Nucleus; Cobalt; Cytochrome P-450 Enzyme System; Genes; Heme; Kinetics; Methylcholanthrene; Rats; RNA, Messenger; Transcription, Genetic | 1988 |
Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Glutethimide; Heme; Heme Oxygenase (Decyclizing); Liver; Mephenytoin; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Porphyrins | 1988 |
Heme is a positive regulator of cytochrome P-450 gene transcription.
Topics: Amitrole; Animals; Base Sequence; Cobalt; Cytochrome P-450 Enzyme System; DNA; DNA, Recombinant; Heme; Male; Methylcholanthrene; Molecular Sequence Data; Nucleic Acid Hybridization; Rats; RNA, Messenger; Thioacetamide; Transcription, Genetic | 1988 |
Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Heme; Levulinic Acids; Liver; Methylcholanthrene; Porphobilinogen; Porphyrins | 1987 |
Studies on the induction of serum hemopexin by pentobarbital and polycyclic hydrocarbons.
Topics: Animals; Benzopyrenes; Beta-Globulins; Chloramphenicol; Cycloheximide; Drug Tolerance; Heme; Hemopexin; Immunodiffusion; Male; Methylcholanthrene; Pentobarbital; Polycyclic Compounds; Rabbits; Starvation; Time Factors | 1972 |
Preparation of partially purified, lipid-depleted cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase from rat liver microsomes.
Topics: Animals; Cholic Acids; Chromatography, DEAE-Cellulose; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Detergents; Heme; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Phospholipids; Rats; Spectrophotometry; Ultrafiltration | 1974 |
Ligand interactions with hemoprotein P-450. II. Influence of phenobarbital and methylcholanthrene induction processes on P-450 spectra.
Topics: Amines; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Heme; Imidazoles; Liver; Male; Methylcholanthrene; Microsomes; Myoglobin; Phenobarbital; Protein Biosynthesis; Rabbits; Spectrophotometry; Stimulation, Chemical | 1969 |
Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes.
Topics: Acetamides; Allyl Compounds; Animals; Bacillus subtilis; Carbon Monoxide; Cell Fractionation; Chick Embryo; Cytochromes; Depression, Chemical; Detergents; Etiocholanolone; Female; Flavins; Heme; Ketosteroids; Liver; Methods; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Nitrogen; Oxidoreductases; Peptide Hydrolases; Phenobarbital; Pregnanes; Rats; Solubility; Spectrophotometry; Stimulation, Chemical | 1971 |
Induction of drug metabolism. VII. Differences in P-420 hemoproteins from untreated and 3-methylcholanthrene-treated rats.
Topics: Animals; Biotransformation; Blood Proteins; Carbon Monoxide; Centrifugation, Density Gradient; Cytochromes; Electrophoresis, Disc; Heme; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sucrose; Time Factors; Tritium | 1973 |
Characterization of the heme of cytochrome P-450 using gas chromatography-mass spectrometry.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Heme; Hemoglobins; Humans; Male; Mass Spectrometry; Membranes; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Rabbits; Rats; Solubility | 1973 |
The effect of phenobarbital, 3-methylcholanthrene, 3,4-benzpyrene, and pregnenolone-16 alpha-carbonitrile on microsomal heme oxygenase and splenic cytochrome P-450.
Topics: Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Heme; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Spleen; Time Factors | 1974 |
Effects of phenobarbital, 3-methylcholanthrene, and hematin on the synthesis of protein components of rat liver microsomal membranes.
Topics: Animals; Carbon Isotopes; Cytochromes; Electrophoresis; Endoplasmic Reticulum; Heme; Leucine; Male; Membranes; Metabolism; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Sodium Dodecyl Sulfate; Solubility; Tritium | 1972 |
Effect of 3-methylcholanthrene induction on the carbon tetrachloride-induced changes in rat hepatic microsomal enzyme system.
Topics: Animals; Benzopyrenes; Carbon Tetrachloride Poisoning; Cytochromes; Enzyme Induction; Heme; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Morphine; Rats | 1972 |
A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.
Topics: 1-Propanol; Amines; Animals; Chemical Phenomena; Chemistry; Chlorides; Cycloheximide; Cytochromes; Fasting; Fatty Alcohols; Heme; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Mercury; Methylcholanthrene; Microsomes, Liver; Nitriles; Oxidation-Reduction; Phenobarbital; Potassium; Protein Biosynthesis; Rats; Spectrophotometry; Sulfites; Thiocyanates; Triazoles | 1971 |
Chromatography of radioactive microsomal hemoproteins on diethylaminoethyl cellulose.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Solubility; Time Factors; Tritium | 1971 |
Effects of inducers of liver microsomal enzymes on the composition of microsomal hemoprotein.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlordan; Cytochromes; Enzyme Induction; Heme; Hemeproteins; Hydroxylation; In Vitro Techniques; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Time Factors; Tritium | 1971 |
Pharmacologic induction of serum hemopexin by 3-methylcolanthrene and allylisopropylacetamide.
Topics: Amides; Animals; Blood Coagulation Factors; Enzyme Induction; Ethionine; Heme; Injections, Intraperitoneal; Injections, Subcutaneous; Methylcholanthrene; Microsomes; Rabbits; Transferrin | 1970 |
Effect of methylcholanthrene or phenobarbital pretreatment of rabbits and rats on the extinction coefficient for cytochrome P-450.
Topics: Animals; Cytochromes; Enzyme Induction; Heme; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Rats | 1971 |
Biphasic decrease of radioactive hemoprotein from liver microsomal CO-binding particles. Effect of 3-methylcholanthrene.
Topics: Amino Acids; Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Heme; Levulinic Acids; Liver; Male; Methods; Methylcholanthrene; Microsomes; Protein Binding; Protein Biosynthesis; Rats; Solubility; Spectrum Analysis; Time Factors; Tritium | 1969 |
Regulation of the synthesis of cytochrome P-450 in liver.
Topics: Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Methylcholanthrene; Phenobarbital; Poly A; Protein Biosynthesis; Rats; RNA; RNA, Messenger | 1981 |
Hematin-mediated increases of benzo(a)pyrene mono-oxygenation in maternal, fetal and placental tissues of inducible and non-inducible mouse strains.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrene Hydroxylase; Benzopyrenes; Carcinogens; Enzyme Induction; Female; Fetus; Heme; Hemin; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Placenta; Pregnancy | 1983 |
7-Ethoxycoumarin deethylase activity as a convenient measure of liver drug metabolizing enzymes: regulation in cultured rat hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Animals; Bucladesine; Cells, Cultured; Dexamethasone; Enzyme Induction; Glucagon; Heme; Insulin; Liver; Methylcholanthrene; Niacinamide; Oxygenases; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains | 1984 |
Turnover of two drug-inducible forms of microsomal cytochrome P-450 in rat liver.
Topics: Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Half-Life; Heme; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Activation of 3,4,3',4'-tetrachlorobiphenyl to protein-bound metabolites by rat liver microsomal cytochrome P-448-containing monooxygenase system.
Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Protein Binding; Rats; Rats, Inbred Strains; Substrate Specificity | 1983 |
Reversible transfer of heme between different molecular species of microsome-bound cytochrome P-450 in rat liver.
Topics: Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Heme; Isoenzymes; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats | 1983 |
Magnetic circular dichroism studies of cytochrome P-450cam. Characterization of axial ligands of ferric and ferrous low-spin complexes.
Topics: Animals; Circular Dichroism; Cytochrome P-450 Enzyme System; Cytochromes; Cytochromes b5; Heme; Ligands; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Protein Conformation; Pseudomonas; Rabbits | 1981 |
Inactivation of hepatic cytochrome P-450 by allenic substrates.
Topics: Alkadienes; Animals; Cytochrome P-450 Enzyme Inhibitors; Enzyme Induction; Heme; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rats | 1980 |
Microsomal NADPH-dependent lipid peroxidation does not require the presence of intact cytochrome P450.
Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Pregnenolone Carbonitrile; Rats | 1980 |
Mechanism-based inactivation of hepatic ethoxyresorufin O-dealkylation activity by naturally occurring coumarins.
Topics: Animals; Anticoagulants; Anticonvulsants; Carbon Radioisotopes; Carcinogens; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP1A1; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Furocoumarins; Heme; Humans; Hypnotics and Sedatives; Methylcholanthrene; Mice; Mice, Inbred SENCAR; Microsomes, Liver; Phenobarbital; Plant Extracts; Radioligand Assay | 1996 |
Regulation of constitutive rat hepatic cytochromes P450 by 3-methylcholanthrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Female; Heme; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Inbred F344; Receptors, Aryl Hydrocarbon; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1996 |