3-methylcholanthrene and fluorouracil

3-methylcholanthrene has been researched along with fluorouracil in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199018 (72.00)18.7374
1990's4 (16.00)18.2507
2000's1 (4.00)29.6817
2010's1 (4.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Hiraiwa, K; Ichikawa, H; Kaneda, T1
Belitskiĭ, GA; Bukhman, VM; Konopleva, IA1
Getz, MJ; Moses, HL; Swartzendruber, DE; Wells, DJ1
Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O1
Ebina, T; Murata, K1
Krosnick, JA; McIntosh, JK; Mulé, JJ; Rosenberg, SA1
Hirata, M; Kamata, S; Tonda, K1
Curschellas, E; Matter, A; Müller, M; Regenass, U1
Huebner, RJ; Rhim, JS; Ro, HS; Vernon, ML; Wuu, KD1
Stárka, L1
Duprez, A; Kissel, P; Robert, J1
Adelberg, MG; Cohen, D; Haber, M; Mekori, T; Robinson, E; Weiss, DW; Yron, I1
Heidelberger, C1
Rees, ED; Ross, A1
Baserga, R; McDonough, M; Sasaki, T; Shimkin, MB; Thatcher, D; Wieder, R1
Hayashi, I; Hiasa, Y; Yamashita, A; Yoshida, K; Yoshikawa, K1
Gropper, L; Shimkin, MB1
Ezoe, I; Hatsuse, K; Hiraide, H; Iwasa, H; Kadota, T; Kanabe, S; Kurokawa, T; Mimura, K; Mizoguchi, O; Ohsaki, Y; Tamaki, K; Tsuru, S; Zinnaka, Y1
Belitsky, GA; Bukhman, VM; Konopleva, IA1
Albino, AP; Altorki, NK; Blundell, ML; de Oliveira, AR; Kelsen, DP; Lai, L; Loganzo, F; Maslak, P; Nabeya, Y; Schwartz, GK1
Doi, K; Itoh, H; Okada, S; Oku, N; Sakai, A; Shuto, S; Toyota, T1
BRESNICK, E; YANG, HY1
Bae, SK; Choi, YH; Kim, SO; Lee, MG1
Goebel, S; Hoelzer, D; Leovsky, C; Meyer, FB; Spangel, SB; Thierbach, R1

Reviews

2 review(s) available for 3-methylcholanthrene and fluorouracil

ArticleYear
[Antiandrogens].
    Ceskoslovenska farmacie, 1970, Volume: 19, Issue:3

    Topics: Acetates; Adrenal Cortex Hormones; Androgen Antagonists; Animals; Antimetabolites; Castration; Chickens; Chlormadinone Acetate; Female; Feminization; Fetus; Fluorouracil; Hydroxyprogesterones; Male; Methylcholanthrene; Mice; Pregnancy; Progesterone; Prostate; Rats; Seminal Vesicles; Steroids; Testolactone; Testosterone

1970
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Deoxyribonucleases; DNA; Fluorouracil; Humans; Liver Neoplasms; Methylcholanthrene; Mice; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Oncogenic Viruses; Orotic Acid; Phenanthrenes; Protein Binding; Pyrimidinones; Rats; Skin Neoplasms; Thymine; Uracil

1970

Other Studies

23 other study(ies) available for 3-methylcholanthrene and fluorouracil

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
[Experimental study relating to the anti-cancer effect of FT-207 suppository (author's transl)].
    Nihon Gan Chiryo Gakkai shi, 1979, Oct-20, Volume: 14, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Female; Fluorouracil; Methylcholanthrene; Mice; Neoplasms, Experimental; Skin Neoplasms; Suppositories; Tegafur

1979
[Change of toxic and antineoplastic properties of ftorafur by means of action on nonspecific microsomal oxidase].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:10

    Topics: Animals; Drug Antagonism; Drug Synergism; Enzyme Induction; Fluorouracil; Leukemia, Experimental; Methylcholanthrene; Mice; Microsomes; Oxidoreductases; Phenobarbital; Premedication; Proadifen; Rauscher Virus; Spleen; Tegafur

1979
Comparison of RNA metabolism in G1-arrested and stimulated nontransformed and chemically transformed mouse embryo cells in culture.
    Cancer research, 1979, Volume: 39, Issue:11

    Topics: Amanitins; Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Embryo, Mammalian; Fluorouracil; Interphase; Methylcholanthrene; Mice; Poly A; Polyribosomes; RNA; RNA Polymerase II

1979
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L1210; Leukemia P388; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Sarcoma 180; Spleen; Tegafur; Thymus Gland; Uridine

1992
Antitumor effect of PSK at a distant site: tumor-specific immunity and combination with other chemotherapeutic agents.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:7

    Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Drug Synergism; Fibrosarcoma; Fluorouracil; Injections, Intralesional; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nimustine; Proteoglycans; Sensitivity and Specificity; Transplantation, Heterologous

1992
Augmentation of antitumor efficacy by the combination of recombinant tumor necrosis factor and chemotherapeutic agents in vivo.
    Cancer research, 1989, Jul-15, Volume: 49, Issue:14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Methylcholanthrene; Mice; Mice, Inbred C57BL; Recombinant Proteins; Sarcoma, Experimental; Tumor Necrosis Factor-alpha

1989
Metabolism of 1-phthalidyl 5-fluorouracil in rat liver and enzyme induction by phenobarbital.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:6

    Topics: Aldehyde Oxidoreductases; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Stability; Enzyme Induction; Fluorouracil; Hydrolases; In Vitro Techniques; Liver; Male; Methylcholanthrene; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains; Sarcoma, Experimental

1987
Anti-tumor effects of tumor necrosis factor in combination with chemotherapeutic agents.
    International journal of cancer, 1987, Feb-15, Volume: 39, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Glycoproteins; Methylcholanthrene; Mice; Mice, Inbred Strains; Necrosis; Neoplasm Transplantation; Sarcoma, Experimental; Tumor Necrosis Factor-alpha

1987
Induction of guinea pig leukemia-like virus from cultured guinea pigs cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 147, Issue:1

    Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Clone Cells; Complement Fixation Tests; Cytochalasin B; Enzyme Activation; Fibroblasts; Fluorouracil; Guinea Pigs; Hybrid Cells; Idoxuridine; Kidney; Mercaptopurine; Methylcholanthrene; Microscopy, Electron; Retroviridae; RNA-Directed DNA Polymerase; Spleen; Time Factors

1974
[Action of 5-fluoro-uracil on the synthesis of DNA by a methylcholanthrene-induced rhabdomyosarcoma in the C57-Br mouse].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1966, Volume: 160, Issue:8

    Topics: Animals; DNA, Neoplasm; Fluorouracil; Methylcholanthrene; Mice; Rhabdomyosarcoma; Sarcoma, Experimental

1966
Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.
    National Cancer Institute monograph, 1973, Volume: 39

    Topics: Animals; Antigens, Bacterial; BCG Vaccine; Benzopyrenes; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Immunity, Cellular; Male; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mycobacterium bovis; Neoplasm Transplantation; Sarcoma, Experimental; Thiotepa; Transplantation, Homologous; Vinblastine

1973
Influence of five anti-cancer drugs on the induction and growth of experimental mammary cancers: comparison with ovariectomy.
    Cancer, 1968, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents; Castration; Cyclophosphamide; Female; Fluorouracil; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methotrexate; Methylcholanthrene; Rats; Thiotepa; Vinblastine

1968
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
    Cancer research, 1969, Volume: 29, Issue:5

    Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Lung Neoplasms; Male; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms, Experimental; Puromycin; Thymidine; Tritium; Urethane

1969
[Studies on the treatment of experimental renal tumors induced by dimethylnitrosamine. I. The effects of mitomycin C, 5-fluorouracil, 3-methyl-cholanthrene, alpha-naphthyl-isothiocyanate and diethylstilbestrol on experimentally induced renal tumors].
    Hinyokika kiyo. Acta urologica Japonica, 1969, Volume: 15, Issue:2

    Topics: Animals; Antineoplastic Agents; Diethylstilbestrol; Fluorouracil; Kidney Neoplasms; Male; Methylcholanthrene; Mitomycins; Nitrosamines; Rats; Thiocyanates

1969
Combination therapy of 3-methylcholanthrene-induced mammary carcinoma in rats: effect of chemotherapy, ovariectomy, and food restriction.
    Cancer research, 1967, Volume: 27, Issue:1

    Topics: Animals; Estradiol; Fluorouracil; Lucanthone; Mammary Neoplasms, Experimental; Methylcholanthrene; Mitomycins; Progesterone; Rats; Starvation; Testosterone; Triazines; Uracil

1967
[Effect of solcoseryl and combined therapy of solcoseryl and FT-207 for mice bearing meth-A tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:2 Pt

    Topics: Actihaemyl; Animals; Drug Therapy, Combination; Fluorouracil; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; T-Lymphocytes; Tegafur; Tissue Extracts

1983
Changes in toxic and antitumor properties of ftorafur by induction or inhibition of the microsomal enzymes activity.
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Fluorouracil; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Tegafur

1981
The mutational status of p53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents.
    International journal of cancer, 1995, Feb-20, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cisplatin; DNA Damage; Esophageal Neoplasms; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; In Vitro Techniques; Methylcholanthrene; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1995
Therapeutic effect of reticuloendothelial system (RES)-avoiding liposomes containing a phospholipid analogue of 5-fluorouracil, dipalmitoylphosphatidylfluorouridine, in Meth A sarcoma-bearing mice.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:10

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antineoplastic Agents; Cell Division; Drug Carriers; Drug Delivery Systems; Fluorouracil; Glucuronates; Glycerophospholipids; Injections, Intravenous; Lipid Bilayers; Liposomes; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mononuclear Phagocyte System; Phosphatidic Acids; Phosphatidylglycerols; Phospholipids; Sarcoma, Experimental; Uridine

1994
THE INFLUENCE OF PHENOBARBITAL ADMINISTRATION UPON THE "SOLUBLE" NADP-REQUIRING ENZYMES IN LIVER.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aminopyrine; Benzopyrenes; Citrates; Diphenhydramine; Ethionine; Fluorouracil; Gluconates; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Mercaptopurine; Methylcholanthrene; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylalanine; Rats; Research; Uracil

1964
Pharmacokinetics of 5-fluorouracil in mutant Nagase analbuminemic rats: faster metabolism of 5-fluorouracil via CYP1A.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:2

    Topics: Acetylglucosaminidase; Animals; Antimetabolites; Area Under Curve; Blood Proteins; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Enzyme Inhibitors; Fluorouracil; Half-Life; Injections, Intravenous; Male; Methylcholanthrene; Microdialysis; Proadifen; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin

2007
Metformin alters therapeutic effects in the BALB/c tumor therapy model.
    BMC cancer, 2021, May-28, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; BALB 3T3 Cells; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Culture Media; Docetaxel; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Fluorouracil; Glucose; Humans; Metformin; Methylcholanthrene; Mice; Mitomycin; Neoplasms

2021