Compounds > 3-methylcholanthrene

3-methylcholanthrene and ethoxyresorufin

3-methylcholanthrene has been researched along with ethoxyresorufin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199010 (50.00)18.7374
1990's4 (20.00)18.2507
2000's5 (25.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burke, MD; Kouri, RE; Mayer, RT1
Burke, MD; Orrenius, S1
de la Torre, R; Segura, J; Valero, F1
Cikryt, P; Wiebel, FJ1
Elovaara, E; Gelboin, HV; Hietanen, E; Nakajima, T; Park, SS; Vainio, H1
Juchau, MR; Namkung, MJ; Yang, HY1
Hahnemann, B; Heubel, F; Kühn, B; Legrum, W1
Bement, WJ; Goldstein, JA; Jacobs, JM; Lambrecht, RW; Sinclair, JF; Sinclair, PR1
Grishanova, AIu; Liakhovich, VV; Mishin, VM; Peregoedova, EL1
James, OF; Mutch, E; Rawlins, MD; Woodhouse, KW; Wynne, H1
Adams, DJ; Amelizad, Z; Oesch, F; Seilman, S; Wolf, CR1
Godden, PM; Ioannides, C; Lum, PY; Parke, DV; Phillipson, CE1
Burke, MD; Lees, GM; Murray, GI1
Castell, JV; Donato, MT; Gómez-Lechón, MJ1
Bement, WJ; Dalton, TP; Gorman, N; Nebert, DW; Sinclair, JF; Sinclair, PR; Smith, AG; Walton, HS1
Kelly, JH; Sussman, NL1
Dayal, M; Dey, A; Dhawan, A; Parmar, D; Seth, PK1
Deschaux, P; Marionnet, D; Reynaud, S1
Arizono, K; Goka, K; Hinton, DE; Kashiwada, S; Ozato, K; Shiraishi, H; Wakamatsu, Y1
Mullen Grey, AK; Riddick, DS1

Other Studies

20 other study(ies) available for 3-methylcholanthrene and ethoxyresorufin

ArticleYear
3-methylcholanthrene-induced monooxygenase (O-deethylation) activity of human lymphocytes.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cytochromes; Enzyme Induction; Female; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Male; Methylcholanthrene; Mixed Function Oxygenases; NAD; Oxazines; Oxidoreductases

1977
The effect of albumin on the metabolism of ethoxyresorufin through O-deethylation and sulphate-conjugation using isolated rat hepatocytes.
    Biochemical pharmacology, 1978, Volume: 27, Issue:11

    Topics: Albumins; Animals; Cattle; Dealkylation; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Oxazines; Rats; Salicylamides; Serum Albumin, Bovine; Sulfates

1978
Selective in-vitro inhibition of hepatic oxidative metabolism by quinolones: 7-ethoxyresorufin and caffeine as model substrates.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:1

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Caffeine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains

1991
Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor.
    Chemico-biological interactions, 1990, Volume: 76, Issue:3

    Topics: Animals; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Cytosol; Dexamethasone; Enzyme Induction; Hydrocarbons; Hydroxylation; Kinetics; Liver Neoplasms; Methylcholanthrene; Oxazines; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Tritium; Tumor Cells, Cultured

1990
Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Benzene; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1990
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac

1989
Selective induction of the coumarin hydroxylase by N-containing heteroaromatic compounds.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Enzyme Induction; Ethylmorphine; Heterocyclic Compounds; Imidazoles; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Oxazines; Phenobarbital; Pyrazoles; Pyridines; Structure-Activity Relationship

1989
Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d.
    The Biochemical journal, 1989, Feb-15, Volume: 258, Issue:1

    Topics: Animals; Antibodies; Chick Embryo; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Immunoblotting; Kidney; Methylcholanthrene; Microsomes, Liver; o-Aminoazotoluene; Oxazines; Oxidation-Reduction; Phenobarbital; Porphyrinogens; Rats; Uroporphyrinogens

1989
[Relation between the 7-ethoxyresorufin-O-deethylase activity of the liver microsomal monooxygenase system and the level of methylcholanthrene-induced form of cytochrome P-450].
    Biokhimiia (Moscow, Russia), 1988, Volume: 53, Issue:6

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains

1988
The effect of age on mono-oxygenase enzyme kinetics in rat liver microsomes.
    Age and ageing, 1987, Volume: 16, Issue:3

    Topics: Aging; Aldrin; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Kinetics; Methylcholanthrene; Microsomes, Liver; Oxazines; Phenobarbital; Rats

1987
Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat.
    The Biochemical journal, 1985, Dec-15, Volume: 232, Issue:3

    Topics: Animals; Antibodies; Coumarins; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity

1985
Determination of cytochrome P-448 activity in biological tissues.
    The Biochemical journal, 1984, Jul-01, Volume: 221, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Ellipticines; In Vitro Techniques; Male; Methods; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Rats; Rats, Inbred Strains; Substrate Specificity

1984
Fluorescence-microscopic measurement of intracellular cytochrome P-450 enzyme activity (ethoxyresorufin O-de-ethylation) in unfixed liver section.
    The Biochemical journal, 1983, Apr-15, Volume: 212, Issue:1

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; In Vitro Techniques; Intracellular Fluid; Kinetics; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Oxazines; Salicylamides

1983
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Adult; Aged; Cells, Cultured; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Ethanol; Female; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Nitrophenols; Oxazines; Oxidation-Reduction; Phenobarbital; Safrole; Substrate Specificity; Testosterone

1995
CYP1A2 is essential in murine uroporphyria caused by hexachlorobenzene and iron.
    Toxicology and applied pharmacology, 2000, Jan-01, Volume: 162, Issue:1

    Topics: Aminolevulinic Acid; Animals; Antibodies; Blotting, Western; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Imidazoles; Iron; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxazines; Oxidation-Reduction; Phenobarbital; Time Factors; Uroporphyrinogens; Uroporphyrins

2000
A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition.
    Journal of biomolecular screening, 2000, Volume: 5, Issue:4

    Topics: Cell Line; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Enzyme Inhibitors; Fluorescence; Humans; Methylcholanthrene; Oxazines; Theophylline

2000
Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression.
    Life sciences, 2001, Jun-15, Volume: 69, Issue:4

    Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Carcinogens; Catalysis; Cytochrome P-450 CYP1A1; Enzyme Induction; Isoenzymes; Lymphocytes; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2001
Possible implication of macrophages in the regulation of cytochrome P450 activities in carp (Cyprinus carpio).
    Fish & shellfish immunology, 2006, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Carps; Cytochrome P-450 Enzyme System; Dextran Sulfate; Gene Expression Regulation; Kidney; Leukocytes; Lipopolysaccharides; Liver; Macrophage-Activating Factors; Macrophages; Methylcholanthrene; Oxazines; Respiratory Burst; Spleen; Tilorone

2006
Age-dependent in situ hepatic and gill CYP1A activity in the see-through medaka (Oryzias latipes).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2007, Volume: 145, Issue:1

    Topics: Aging; Animals; Cytochrome P-450 CYP1A1; Enzyme Induction; Female; Gills; Larva; Liver; Male; Methylcholanthrene; Microscopy, Fluorescence; Oryzias; Oxazines; Oxidation-Reduction

2007
The aryl hydrocarbon receptor pathway and the response to 3-methylcholanthrene are altered in the liver of adrenalectomized rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Actins; Adrenalectomy; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Liver; Male; Methylcholanthrene; NADPH-Ferrihemoprotein Reductase; Oxazines; Rats; Rats, Inbred F344; Receptors, Aryl Hydrocarbon; RNA, Messenger

2011