3-methylcholanthrene and dimethylnitrosamine

3-methylcholanthrene has been researched along with dimethylnitrosamine in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199040 (85.11)18.7374
1990's5 (10.64)18.2507
2000's1 (2.13)29.6817
2010's1 (2.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Hackney, C; Hutton, JJ; Meier, J2
Arcos, JC; Argus, MF; Bryant, GM; Pastor, KM2
Arcos, JC; Argus, MF; Brown, CE; Davies, DL1
Matsushima, T; Sugimura, T1
Drevon, C; Kuroki, T; Montesano, R1
Connor, TH; Forti, GC; Legator, MS; Sitra, P1
Guengerich, FP1
Heidelberger, C; Lillehaug, JR; Mondal, S1
Kleeberg, U; Neupert, G; Thust, R1
Baldy, WJ; Hong, YS; Lotlikar, PD1
Syrowatka, T; Wiadrowska, B1
Banerjee, S; Conney, AH; Kuntzman, R; Levin, W; Somogyi, A1
Friedman, MA; Staub, J1
Beliaeva, NM; Kozhevnikova, EP; Matchin, GA1
Arcos, JC; Argus, MF; Bryant, GM; Davies, DL1
Handler, AH; Homburger, F; Hsueh, SS; Russfield, AB; Soto, E; Van Dongen, CG1
Baldy, WJ; Dwyer, EN; Lotlikar, PD; Nyce, J1
Frantz, CN; Malling, HV1
Czygan, P; Garro, AJ; Greim, H; Hutterer, F; Popper, H; Schaffner, F1
Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Phillips, JC1
Arcos, JC; Argus, MF; Bryant, GM; Buu-Hoi, NP; Valle, RT1
Arcos, JC; Argus, MF; Pastor, KM; Venkatesan, N; Wu, BC1
Arcos, JC; Argus, MF1
Beck, DJ; Li, AP; Teepe, AG1
Elias, R; Nagabhushan, M; Ng, YK; Polverini, PJ; Solt, DB1
Majeska, JB; Matheson, DW1
Lü, MD; Miyazaki, K; Nakayama, F1
Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM1
Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A1
Dietz, D; Kornbrust, D1
Bosmann, HB; Chin, AE1
Shertzer, HG1
Breen, PA; Sivak, A; Tu, AS1
Kasuya, Y; Kawanishi, T; Nakadate, M; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A1
Anderson, LM; Angel, M1
Arany, I; Boján, F; Kertai, P; Rády, P; Uzvölgyi, E1
Barnhart, BJ; Chen, DJ; Okinaka, RT; Strniste, GF1
Arcos, JC; Argus, MF; Bryant, GM; Lai, DY; Myers, SC; Woo, YT1
Kleeberg, U; Klinger, W1
Arcos, JC; Argus, MF; Hoch-Ligeti, C1
Aune, T; Dybing, E; Nelson, SD; Thorgeirsson, SS1
Arcos, JC; Argus, MF; Lai, DY1
Cantelli-Forti, G; Mesirca, R; Paolini, M; Pozzetti, L; Sapone, A1
Hioki, K; Hirose, M; Ishii, Y; Kanki, K; Kodama, Y; Kuroiwa, Y; Kurokawa, Y; Nishikawa, A; Nomura, T; Umemura, T1

Reviews

1 review(s) available for 3-methylcholanthrene and dimethylnitrosamine

ArticleYear
Experimental carcinogenesis in small aquarium fishes.
    Progress in experimental tumor research, 1976, Volume: 20

    Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cycasin; Diethylnitrosamine; Dimethylnitrosamine; Female; Fishes; Goldfish; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Sterigmatocystin; Trout

1976

Other Studies

46 other study(ies) available for 3-methylcholanthrene and dimethylnitrosamine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.
    Mutation research, 1979, Volume: 66, Issue:1

    Topics: Animals; Benzopyrenes; Biotransformation; Dimethylnitrosamine; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Mutagens; Nitrosamines; Phenobarbital; Polychlorinated Biphenyls; Tissue Distribution

1979
Mutagenicity and metabolism of dimethylnitrosamine and benzo[alpha]pyrene in tissue homogenates from inbred Syrian hamsters treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.
    Mutation research, 1979, Volume: 64, Issue:6

    Topics: Animals; Benzopyrenes; Biotransformation; Cricetinae; Dimethylnitrosamine; Female; Genetic Techniques; Inbreeding; Intestinal Mucosa; Liver; Lung; Mesocricetus; Methylcholanthrene; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonella typhimurium

1979
Structural limits of specificity of methylcholanthrene-repressible nitrosamine N-dealkylases. Inhibition by analog substrates.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Jun-15, Volume: 86, Issue:2

    Topics: Animals; Binding Sites; Dealkylation; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Nitrosamines; Oxidoreductases; Rats

1976
Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1977, Jun-27, Volume: 89, Issue:2

    Topics: Animals; Dimethylnitrosamine; Enzyme Induction; Enzyme Repression; Humans; Liver; Methylcholanthrene; Mice; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Structure-Activity Relationship

1977
Microsome-mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Acetonitriles; Animals; Azaguanine; Cell Line; Cell Survival; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Rats; Salmonella typhimurium

1977
Bile as a source of mutagenic metabolites produced in vivo and detected by Salmonella typhimurium.
    Environmental mutagenesis, 1979, Volume: 1, Issue:3

    Topics: Acetaminophen; Animals; Bile; Biotransformation; Cyclophosphamide; Diethylstilbestrol; Dimethylnitrosamine; Ethylene Dichlorides; Hycanthone; Isoniazid; Male; Methyl Methanesulfonate; Methylcholanthrene; Mutagens; Rats; Salmonella typhimurium; Serum Albumin, Bovine

1979
Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.
    The Journal of biological chemistry, 1977, Jun-10, Volume: 252, Issue:11

    Topics: Aflatoxins; Animals; Benzopyrenes; Benzphetamine; Carbamates; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Furans; Lung; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Parathion; Phenobarbital; Pyrrolizidine Alkaloids; Rabbits; Rats; Terpenes; Toxins, Biological

1977
Establishment of epithelial cell lines from adult mouse regenerating liver.
    In vitro, 1979, Volume: 15, Issue:11

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Cell Division; Cell Line; Chromosomes; Clone Cells; Dimethylnitrosamine; Diploidy; Epithelium; Liver; Liver Regeneration; Methylcholanthrene; Mice

1979
No neoplastic alteration of metabolically competent rat liver cells in vitro by chemical carcinogens: 3-methylcholanthrene, dimethylnitrosamine and Natulan.
    Cancer biochemistry biophysics, 1978, Volume: 3, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Enzyme Induction; Liver; Methylcholanthrene; Oxidoreductases, N-Demethylating; Procarbazine; Rats

1978
Effect of dimethylnitrosamine concentration on its demethylation by liver microsomes from control and 3-methylcholanthrene pretreated rats, hamsters and guinea pigs.
    Cancer letters, 1978, Volume: 4, Issue:6

    Topics: Animals; Cricetinae; Dimethylnitrosamine; Guinea Pigs; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Rats; Species Specificity

1978
The influence of DDT on metabolism of dimethylnitrosamine in rats.
    Toxicology and applied pharmacology, 1978, Volume: 44, Issue:2

    Topics: Animals; DDT; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nitrosamines; Oxidoreductases, O-Demethylating; Rats; Time Factors

1978
Effect of polychlorinated biphenyls (Aroclor 1254) on inducible and repressible microsomal N-demethylases in the mouse and rat.
    Cancer research, 1975, Volume: 35, Issue:6

    Topics: Animals; Aroclors; Azo Compounds; Dimethylnitrosamine; Enzyme Induction; Enzyme Repression; Male; Methylcholanthrene; Mice; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Polychlorinated Biphenyls; Starvation

1975
Inhibition of the acute toxicity and adrenocorticolytic effect of 7,12-dimethylbenz(a)anthracene by isopropylvaleramide and allylisopropylacetamide in the rat.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Adrenal Cortex; Adrenal Glands; Allylisopropylacetamide; Amides; Animals; Barbiturates; Benz(a)Anthracenes; Benzopyrenes; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Liver; Methylcholanthrene; Pentobarbital; Phenobarbital; Proadifen; Rats; Secobarbital; Time Factors; Valerates

1975
Induction of micronuclei in mouse and hamster bone-marrow by chemical carcinogens.
    Mutation research, 1977, Volume: 43, Issue:2

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cricetinae; Dimethylnitrosamine; Erythrocytes; Female; Fluorenes; Injections, Intraperitoneal; Male; Methylcholanthrene; Mice; Nitrosamines

1977
[Respiration and oxidative phosphorylation in rat kidney mitochondria exposed to the action of a carcinogenic substance].
    Voprosy onkologii, 1977, Volume: 23, Issue:8

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Kidney; Methylcholanthrene; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Rats; Time Factors

1977
Age-dependence of hepatic dimethylnitrosamine-demethylase activity in the rat.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:5

    Topics: Aging; Animals; Dimethylnitrosamine; Liver; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Rats

1976
Adenocarcinoma of the glandular stomach following 3-methylcholanthrene, N-nitrosodiethylamine, or N-nitrosodimethylamine feeding in carcinogen-susceptible inbred Syrian.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:1

    Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Female; Male; Mesocricetus; Methylcholanthrene; Neoplasms, Experimental; Nitrosamines; Species Specificity; Stomach Neoplasms

1976
Phospholipid requirement for dimethylnitrosamine demethylation by hamster hepatic microsomal cytochrome P-450 enzyme system.
    The Biochemical journal, 1976, Nov-15, Volume: 160, Issue:2

    Topics: Animals; Butanols; Cricetinae; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dimethylnitrosamine; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phosphatidylcholines; Phospholipids

1976
Factors affecting metabolism and mutagenicity of dimethylnitrosamine and diethylnitrosamine.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: Animals; Carcinogens; Dealkylation; Diethylamines; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Histidine; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Proadifen; Salmonella typhimurium; Time Factors; Valerates

1975
Cytochrome P-450 in the activation and inactivation of carcinogens.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Animals; Aroclors; Biotransformation; Carcinogens; Choline Deficiency; Cytochrome P-450 Enzyme System; Deficiency Diseases; Dimethylnitrosamine; Humans; In Vitro Techniques; Inactivation, Metabolic; Kinetics; Liver; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Microsomes, Liver; Mutagens; Oxidoreductases, N-Demethylating; Phenobarbital; Photochemistry

1975
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
    Food and cosmetics toxicology, 1975, Volume: 13, Issue:6

    Topics: Age Factors; Aminopyrine; Aniline Hydroxylase; Animals; Carbon Dioxide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sex Factors

1975
Dimethylnitrosamine-demethylase: molecular size-dependence of repression by polynuclear hydrocarbons. Nonhydrocarbon repressors.
    Journal of toxicology and environmental health, 1976, Volume: 1, Issue:3

    Topics: Animals; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Oxidoreductases, N-Demethylating; Phenobarbital; Polycyclic Compounds; Pregnenolone Carbonitrile; Rats

1976
Dimethylnitrosamine-demethylase: absence of increased enzyme catabolism and multiplicity of effector sites in repression. Hemoprotein involvement.
    Chemico-biological interactions, 1976, Volume: 13, Issue:2

    Topics: Animals; Carbon Monoxide; Caseins; Cytochrome P-450 Enzyme System; Dietary Proteins; Dimethylnitrosamine; Enzyme Repression; Hemeproteins; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats

1976
Hydrocarbon-nitrosamine synergism as a possible amplifying factor in lung tumorigenesis by tobacco smoke.
    Journal of theoretical biology, 1976, Volume: 56, Issue:2

    Topics: Animals; Benzopyrenes; Dimethylnitrosamine; Drug Synergism; Epoxide Hydrolases; Lung Neoplasms; Methylcholanthrene; Mice; Nitrosamines; Piperidines; Rats; Smoking

1976
Comparison of rat liver parenchymal and nonparenchymal cells in the activation of promutagens.
    Environmental and molecular mutagenesis, 1992, Volume: 20, Issue:2

    Topics: Animals; Biotransformation; CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Mutagenesis; Mutagenicity Tests; Mutagens; Prodrugs; Rats; Rats, Inbred Strains; Thioguanine

1992
Acute inhibition of DNA synthesis in hamster buccal pouch epithelium exposed to indirect acting carcinogens.
    Cancer letters, 1990, Volume: 53, Issue:2-3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Cell Division; Cricetinae; Dimethylnitrosamine; DNA; Male; Mesocricetus; Methylcholanthrene; Mouth Mucosa; Necrosis; Time Factors

1990
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:4

    Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Dimethylnitrosamine; Lymphoma; Methylcholanthrene; Mice; Microsomes, Liver; Mutagenicity Tests; NADP; Thymidine Kinase; Time Factors; Tumor Cells, Cultured

1990
Unscheduled DNA synthesis after treatment with 20-methylcholanthrene and N-nitrosodimethylamine in primary culture of human gallbladder epithelial cells.
    Mutation research, 1990, Volume: 235, Issue:2

    Topics: Cells, Cultured; Dimethylnitrosamine; DNA Replication; Epithelium; Gallbladder; Humans; Methylcholanthrene

1990
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:3

    Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344

1987
Different effects of chemicals on metabolism of N-nitrosamines in rat liver.
    IARC scientific publications, 1987, Issue:84

    Topics: Animals; Dimethylnitrosamine; Ethanol; Liver; Methylcholanthrene; Nitrosamines; Phenobarbital; Pyrazoles; Rats

1987
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
    Chemico-biological interactions, 1985, Dec-17, Volume: 56, Issue:1

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains

1985
Hepatic microsomal metabolism of N-nitrosodimethylamine to its methylating agent.
    Toxicology and applied pharmacology, 1980, Jun-15, Volume: 54, Issue:1

    Topics: Alkylating Agents; Animals; Dimethylnitrosamine; DNA; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Proteins; Rats; RNA

1980
Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules.
    Chemico-biological interactions, 1984, Volume: 48, Issue:1

    Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Dimethylnitrosamine; DNA; Indoles; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Phenobarbital; Rats

1984
Comparison of primary hepatocytes and S9 metabolic activation systems for the C3H-10T 1/2 cell transformation assay.
    Carcinogenesis, 1984, Volume: 5, Issue:11

    Topics: Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cyclophosphamide; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Microsomes, Liver; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
Effect of phenobarbital and 3-methylcholanthrene on the hepatic microsomal metabolism of N-nitrosodimethylamine, N-nitrosomethylbutylamine and N-nitrosomethylbenzylamine.
    Cancer letters, 1983, Volume: 20, Issue:2

    Topics: Animals; Chromatography, Gas; Dimethylnitrosamine; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains

1983
Induction of dimethylnitrosamine demethylase activity in mouse liver by polychlorinated biphenyls and 3-methylcholanthrene.
    Biochemical pharmacology, 1980, May-15, Volume: 29, Issue:10

    Topics: Animals; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Enzyme Induction; In Vitro Techniques; Liver; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases, N-Demethylating; Polychlorinated Biphenyls

1980
Transplacental effects of carcinogens and non-carcinogens on activities of pyruvate kinase and lactate dehydrogenase as well as isozymic pattern of LDH in mouse lung.
    Toxicology, 1982, Volume: 24, Issue:3-4

    Topics: Animals; Carbamates; Carcinogens; Dimethylnitrosamine; Female; Isoenzymes; L-Lactate Dehydrogenase; Lung; Maternal-Fetal Exchange; Methylcholanthrene; Mice; Phenylcarbamates; Pregnancy; Pyrenes; Pyruvate Kinase; Urethane

1982
Induction of 6-thioguanine-resistant mutations by rat-liver homogenate (S9)-activated promutagens in human embryonic skin fibroblasts.
    Mutation research, 1982, Volume: 101, Issue:1

    Topics: Animals; Benzopyrenes; Biotransformation; Cell Line; Dimethylnitrosamine; Drug Resistance; Embryo, Mammalian; Humans; Hypoxanthine Phosphoribosyltransferase; Methylcholanthrene; Microsomes, Liver; Mutagens; Mutation; Rats; Skin; Thioguanine

1982
Evolution of activation-detoxification enzyme patterns during precarcinogenesis in synergism: 3-methylcholanthrene and dimethylnitrosamine.
    Journal of cancer research and clinical oncology, 1982, Volume: 103, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Drug Synergism; Inactivation, Metabolic; Liver; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Oxidoreductases, N-Demethylating; Polycyclic Compounds; Rats; Rats, Inbred Strains

1982
Age course and inducibility of dimethylnitrosamine N-demethylation in rat liver.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:7-8

    Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Kinetics; Liver; Male; Methylcholanthrene; Oxidoreductases, N-Demethylating; Pentobarbital; Rats; Rats, Inbred Strains

1982
Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined.
    Neoplasma, 1982, Volume: 29, Issue:5

    Topics: Adenoma; Animals; Dimethylnitrosamine; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Species Specificity

1982
Genetic differences in dimethylnitrosamine mutagenicity in vitro associated with mouse hepatic aryl hydrocarbon hydroxylase activity induced by 3-methylcholanthrene.
    Acta pharmacologica et toxicologica, 1981, Volume: 48, Issue:2

    Topics: Animals; Dimethylnitrosamine; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens

1981
Interaction of the tobacco-specific nitrosamines, methylethylnitrosamine and N-nitrosonornicotine, with DNA and guanosine.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:1

    Topics: Animals; Benzylamines; Dimethylnitrosamine; DNA; Guanosine; Male; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Nicotiana; Nicotine; Nitrosamines; Phenobarbital; Plants, Toxic; Rats

1980
Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers.
    Chemico-biological interactions, 1995, Mar-30, Volume: 95, Issue:1-2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Barbital; Carcinogens; Cricetinae; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Dimethylnitrosamine; Enzyme Induction; Female; Ketones; Kidney; Liver; Lung; Male; Mesocricetus; Methylcholanthrene; Mice; Mice, Inbred Strains; Phenobarbital; Rats; Rats, Sprague-Dawley; Sex Factors; Species Specificity; Steroid Hydroxylases; Substrate Specificity

1995
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
    Cancer letters, 2006, Jan-18, Volume: 231, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Humans; Incidence; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Transgenic; Oncogene Protein p21(ras)

2006