3-methylcholanthrene has been researched along with dimethylnitrosamine in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 40 (85.11) | 18.7374 |
1990's | 5 (10.64) | 18.2507 |
2000's | 1 (2.13) | 29.6817 |
2010's | 1 (2.13) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Hackney, C; Hutton, JJ; Meier, J | 2 |
Arcos, JC; Argus, MF; Bryant, GM; Pastor, KM | 2 |
Arcos, JC; Argus, MF; Brown, CE; Davies, DL | 1 |
Matsushima, T; Sugimura, T | 1 |
Drevon, C; Kuroki, T; Montesano, R | 1 |
Connor, TH; Forti, GC; Legator, MS; Sitra, P | 1 |
Guengerich, FP | 1 |
Heidelberger, C; Lillehaug, JR; Mondal, S | 1 |
Kleeberg, U; Neupert, G; Thust, R | 1 |
Baldy, WJ; Hong, YS; Lotlikar, PD | 1 |
Syrowatka, T; Wiadrowska, B | 1 |
Banerjee, S; Conney, AH; Kuntzman, R; Levin, W; Somogyi, A | 1 |
Friedman, MA; Staub, J | 1 |
Beliaeva, NM; Kozhevnikova, EP; Matchin, GA | 1 |
Arcos, JC; Argus, MF; Bryant, GM; Davies, DL | 1 |
Handler, AH; Homburger, F; Hsueh, SS; Russfield, AB; Soto, E; Van Dongen, CG | 1 |
Baldy, WJ; Dwyer, EN; Lotlikar, PD; Nyce, J | 1 |
Frantz, CN; Malling, HV | 1 |
Czygan, P; Garro, AJ; Greim, H; Hutterer, F; Popper, H; Schaffner, F | 1 |
Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Phillips, JC | 1 |
Arcos, JC; Argus, MF; Bryant, GM; Buu-Hoi, NP; Valle, RT | 1 |
Arcos, JC; Argus, MF; Pastor, KM; Venkatesan, N; Wu, BC | 1 |
Arcos, JC; Argus, MF | 1 |
Beck, DJ; Li, AP; Teepe, AG | 1 |
Elias, R; Nagabhushan, M; Ng, YK; Polverini, PJ; Solt, DB | 1 |
Majeska, JB; Matheson, DW | 1 |
Lü, MD; Miyazaki, K; Nakayama, F | 1 |
Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM | 1 |
Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
Dietz, D; Kornbrust, D | 1 |
Bosmann, HB; Chin, AE | 1 |
Shertzer, HG | 1 |
Breen, PA; Sivak, A; Tu, AS | 1 |
Kasuya, Y; Kawanishi, T; Nakadate, M; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
Anderson, LM; Angel, M | 1 |
Arany, I; Boján, F; Kertai, P; Rády, P; Uzvölgyi, E | 1 |
Barnhart, BJ; Chen, DJ; Okinaka, RT; Strniste, GF | 1 |
Arcos, JC; Argus, MF; Bryant, GM; Lai, DY; Myers, SC; Woo, YT | 1 |
Kleeberg, U; Klinger, W | 1 |
Arcos, JC; Argus, MF; Hoch-Ligeti, C | 1 |
Aune, T; Dybing, E; Nelson, SD; Thorgeirsson, SS | 1 |
Arcos, JC; Argus, MF; Lai, DY | 1 |
Cantelli-Forti, G; Mesirca, R; Paolini, M; Pozzetti, L; Sapone, A | 1 |
Hioki, K; Hirose, M; Ishii, Y; Kanki, K; Kodama, Y; Kuroiwa, Y; Kurokawa, Y; Nishikawa, A; Nomura, T; Umemura, T | 1 |
1 review(s) available for 3-methylcholanthrene and dimethylnitrosamine
Article | Year |
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Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cycasin; Diethylnitrosamine; Dimethylnitrosamine; Female; Fishes; Goldfish; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Sterigmatocystin; Trout | 1976 |
46 other study(ies) available for 3-methylcholanthrene and dimethylnitrosamine
Article | Year |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.
Topics: Animals; Benzopyrenes; Biotransformation; Dimethylnitrosamine; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Mutagens; Nitrosamines; Phenobarbital; Polychlorinated Biphenyls; Tissue Distribution | 1979 |
Mutagenicity and metabolism of dimethylnitrosamine and benzo[alpha]pyrene in tissue homogenates from inbred Syrian hamsters treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.
Topics: Animals; Benzopyrenes; Biotransformation; Cricetinae; Dimethylnitrosamine; Female; Genetic Techniques; Inbreeding; Intestinal Mucosa; Liver; Lung; Mesocricetus; Methylcholanthrene; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonella typhimurium | 1979 |
Structural limits of specificity of methylcholanthrene-repressible nitrosamine N-dealkylases. Inhibition by analog substrates.
Topics: Animals; Binding Sites; Dealkylation; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Nitrosamines; Oxidoreductases; Rats | 1976 |
Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase.
Topics: Animals; Dimethylnitrosamine; Enzyme Induction; Enzyme Repression; Humans; Liver; Methylcholanthrene; Mice; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Structure-Activity Relationship | 1977 |
Microsome-mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.
Topics: Acetonitriles; Animals; Azaguanine; Cell Line; Cell Survival; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Rats; Salmonella typhimurium | 1977 |
Bile as a source of mutagenic metabolites produced in vivo and detected by Salmonella typhimurium.
Topics: Acetaminophen; Animals; Bile; Biotransformation; Cyclophosphamide; Diethylstilbestrol; Dimethylnitrosamine; Ethylene Dichlorides; Hycanthone; Isoniazid; Male; Methyl Methanesulfonate; Methylcholanthrene; Mutagens; Rats; Salmonella typhimurium; Serum Albumin, Bovine | 1979 |
Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.
Topics: Aflatoxins; Animals; Benzopyrenes; Benzphetamine; Carbamates; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Furans; Lung; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Parathion; Phenobarbital; Pyrrolizidine Alkaloids; Rabbits; Rats; Terpenes; Toxins, Biological | 1977 |
Establishment of epithelial cell lines from adult mouse regenerating liver.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Cell Division; Cell Line; Chromosomes; Clone Cells; Dimethylnitrosamine; Diploidy; Epithelium; Liver; Liver Regeneration; Methylcholanthrene; Mice | 1979 |
No neoplastic alteration of metabolically competent rat liver cells in vitro by chemical carcinogens: 3-methylcholanthrene, dimethylnitrosamine and Natulan.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Enzyme Induction; Liver; Methylcholanthrene; Oxidoreductases, N-Demethylating; Procarbazine; Rats | 1978 |
Effect of dimethylnitrosamine concentration on its demethylation by liver microsomes from control and 3-methylcholanthrene pretreated rats, hamsters and guinea pigs.
Topics: Animals; Cricetinae; Dimethylnitrosamine; Guinea Pigs; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Rats; Species Specificity | 1978 |
The influence of DDT on metabolism of dimethylnitrosamine in rats.
Topics: Animals; DDT; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nitrosamines; Oxidoreductases, O-Demethylating; Rats; Time Factors | 1978 |
Effect of polychlorinated biphenyls (Aroclor 1254) on inducible and repressible microsomal N-demethylases in the mouse and rat.
Topics: Animals; Aroclors; Azo Compounds; Dimethylnitrosamine; Enzyme Induction; Enzyme Repression; Male; Methylcholanthrene; Mice; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Polychlorinated Biphenyls; Starvation | 1975 |
Inhibition of the acute toxicity and adrenocorticolytic effect of 7,12-dimethylbenz(a)anthracene by isopropylvaleramide and allylisopropylacetamide in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Adrenal Cortex; Adrenal Glands; Allylisopropylacetamide; Amides; Animals; Barbiturates; Benz(a)Anthracenes; Benzopyrenes; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Liver; Methylcholanthrene; Pentobarbital; Phenobarbital; Proadifen; Rats; Secobarbital; Time Factors; Valerates | 1975 |
Induction of micronuclei in mouse and hamster bone-marrow by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cricetinae; Dimethylnitrosamine; Erythrocytes; Female; Fluorenes; Injections, Intraperitoneal; Male; Methylcholanthrene; Mice; Nitrosamines | 1977 |
[Respiration and oxidative phosphorylation in rat kidney mitochondria exposed to the action of a carcinogenic substance].
Topics: Animals; Carcinogens; Dimethylnitrosamine; Kidney; Methylcholanthrene; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Rats; Time Factors | 1977 |
Age-dependence of hepatic dimethylnitrosamine-demethylase activity in the rat.
Topics: Aging; Animals; Dimethylnitrosamine; Liver; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Rats | 1976 |
Adenocarcinoma of the glandular stomach following 3-methylcholanthrene, N-nitrosodiethylamine, or N-nitrosodimethylamine feeding in carcinogen-susceptible inbred Syrian.
Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Female; Male; Mesocricetus; Methylcholanthrene; Neoplasms, Experimental; Nitrosamines; Species Specificity; Stomach Neoplasms | 1976 |
Phospholipid requirement for dimethylnitrosamine demethylation by hamster hepatic microsomal cytochrome P-450 enzyme system.
Topics: Animals; Butanols; Cricetinae; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dimethylnitrosamine; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phosphatidylcholines; Phospholipids | 1976 |
Factors affecting metabolism and mutagenicity of dimethylnitrosamine and diethylnitrosamine.
Topics: Animals; Carcinogens; Dealkylation; Diethylamines; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Histidine; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Proadifen; Salmonella typhimurium; Time Factors; Valerates | 1975 |
Cytochrome P-450 in the activation and inactivation of carcinogens.
Topics: Animals; Aroclors; Biotransformation; Carcinogens; Choline Deficiency; Cytochrome P-450 Enzyme System; Deficiency Diseases; Dimethylnitrosamine; Humans; In Vitro Techniques; Inactivation, Metabolic; Kinetics; Liver; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Microsomes, Liver; Mutagens; Oxidoreductases, N-Demethylating; Phenobarbital; Photochemistry | 1975 |
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
Topics: Age Factors; Aminopyrine; Aniline Hydroxylase; Animals; Carbon Dioxide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sex Factors | 1975 |
Dimethylnitrosamine-demethylase: molecular size-dependence of repression by polynuclear hydrocarbons. Nonhydrocarbon repressors.
Topics: Animals; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Oxidoreductases, N-Demethylating; Phenobarbital; Polycyclic Compounds; Pregnenolone Carbonitrile; Rats | 1976 |
Dimethylnitrosamine-demethylase: absence of increased enzyme catabolism and multiplicity of effector sites in repression. Hemoprotein involvement.
Topics: Animals; Carbon Monoxide; Caseins; Cytochrome P-450 Enzyme System; Dietary Proteins; Dimethylnitrosamine; Enzyme Repression; Hemeproteins; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats | 1976 |
Hydrocarbon-nitrosamine synergism as a possible amplifying factor in lung tumorigenesis by tobacco smoke.
Topics: Animals; Benzopyrenes; Dimethylnitrosamine; Drug Synergism; Epoxide Hydrolases; Lung Neoplasms; Methylcholanthrene; Mice; Nitrosamines; Piperidines; Rats; Smoking | 1976 |
Comparison of rat liver parenchymal and nonparenchymal cells in the activation of promutagens.
Topics: Animals; Biotransformation; CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Mutagenesis; Mutagenicity Tests; Mutagens; Prodrugs; Rats; Rats, Inbred Strains; Thioguanine | 1992 |
Acute inhibition of DNA synthesis in hamster buccal pouch epithelium exposed to indirect acting carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Cell Division; Cricetinae; Dimethylnitrosamine; DNA; Male; Mesocricetus; Methylcholanthrene; Mouth Mucosa; Necrosis; Time Factors | 1990 |
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Dimethylnitrosamine; Lymphoma; Methylcholanthrene; Mice; Microsomes, Liver; Mutagenicity Tests; NADP; Thymidine Kinase; Time Factors; Tumor Cells, Cultured | 1990 |
Unscheduled DNA synthesis after treatment with 20-methylcholanthrene and N-nitrosodimethylamine in primary culture of human gallbladder epithelial cells.
Topics: Cells, Cultured; Dimethylnitrosamine; DNA Replication; Epithelium; Gallbladder; Humans; Methylcholanthrene | 1990 |
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344 | 1987 |
Different effects of chemicals on metabolism of N-nitrosamines in rat liver.
Topics: Animals; Dimethylnitrosamine; Ethanol; Liver; Methylcholanthrene; Nitrosamines; Phenobarbital; Pyrazoles; Rats | 1987 |
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
Hepatic microsomal metabolism of N-nitrosodimethylamine to its methylating agent.
Topics: Alkylating Agents; Animals; Dimethylnitrosamine; DNA; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Proteins; Rats; RNA | 1980 |
Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Dimethylnitrosamine; DNA; Indoles; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Phenobarbital; Rats | 1984 |
Comparison of primary hepatocytes and S9 metabolic activation systems for the C3H-10T 1/2 cell transformation assay.
Topics: Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cyclophosphamide; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Microsomes, Liver; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1984 |
Effect of phenobarbital and 3-methylcholanthrene on the hepatic microsomal metabolism of N-nitrosodimethylamine, N-nitrosomethylbutylamine and N-nitrosomethylbenzylamine.
Topics: Animals; Chromatography, Gas; Dimethylnitrosamine; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Induction of dimethylnitrosamine demethylase activity in mouse liver by polychlorinated biphenyls and 3-methylcholanthrene.
Topics: Animals; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Enzyme Induction; In Vitro Techniques; Liver; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases, N-Demethylating; Polychlorinated Biphenyls | 1980 |
Transplacental effects of carcinogens and non-carcinogens on activities of pyruvate kinase and lactate dehydrogenase as well as isozymic pattern of LDH in mouse lung.
Topics: Animals; Carbamates; Carcinogens; Dimethylnitrosamine; Female; Isoenzymes; L-Lactate Dehydrogenase; Lung; Maternal-Fetal Exchange; Methylcholanthrene; Mice; Phenylcarbamates; Pregnancy; Pyrenes; Pyruvate Kinase; Urethane | 1982 |
Induction of 6-thioguanine-resistant mutations by rat-liver homogenate (S9)-activated promutagens in human embryonic skin fibroblasts.
Topics: Animals; Benzopyrenes; Biotransformation; Cell Line; Dimethylnitrosamine; Drug Resistance; Embryo, Mammalian; Humans; Hypoxanthine Phosphoribosyltransferase; Methylcholanthrene; Microsomes, Liver; Mutagens; Mutation; Rats; Skin; Thioguanine | 1982 |
Evolution of activation-detoxification enzyme patterns during precarcinogenesis in synergism: 3-methylcholanthrene and dimethylnitrosamine.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Drug Synergism; Inactivation, Metabolic; Liver; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Oxidoreductases, N-Demethylating; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1982 |
Age course and inducibility of dimethylnitrosamine N-demethylation in rat liver.
Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Kinetics; Liver; Male; Methylcholanthrene; Oxidoreductases, N-Demethylating; Pentobarbital; Rats; Rats, Inbred Strains | 1982 |
Comparative pulmonary tumorigenesis in DBA/2J and C57Bl/6J mice by administration of 3-methylcholanthrene and dimethylnitrosamine singly and combined.
Topics: Adenoma; Animals; Dimethylnitrosamine; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Species Specificity | 1982 |
Genetic differences in dimethylnitrosamine mutagenicity in vitro associated with mouse hepatic aryl hydrocarbon hydroxylase activity induced by 3-methylcholanthrene.
Topics: Animals; Dimethylnitrosamine; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens | 1981 |
Interaction of the tobacco-specific nitrosamines, methylethylnitrosamine and N-nitrosonornicotine, with DNA and guanosine.
Topics: Animals; Benzylamines; Dimethylnitrosamine; DNA; Guanosine; Male; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Nicotiana; Nicotine; Nitrosamines; Phenobarbital; Plants, Toxic; Rats | 1980 |
Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Barbital; Carcinogens; Cricetinae; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Dimethylnitrosamine; Enzyme Induction; Female; Ketones; Kidney; Liver; Lung; Male; Mesocricetus; Methylcholanthrene; Mice; Mice, Inbred Strains; Phenobarbital; Rats; Rats, Sprague-Dawley; Sex Factors; Species Specificity; Steroid Hydroxylases; Substrate Specificity | 1995 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Humans; Incidence; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Transgenic; Oncogene Protein p21(ras) | 2006 |