3-methylcholanthrene and diethylnitrosamine

3-methylcholanthrene has been researched along with diethylnitrosamine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199023 (54.76)18.7374
1990's8 (19.05)18.2507
2000's6 (14.29)29.6817
2010's4 (9.52)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Arcos, JC; Argus, MF; Lai, DY1
Arcos, JC; Argus, MF; Bryant, GM; Pastor, KM1
Fabricius, EA; Schneeweiss, U1
Matsushima, T; Sugimura, T1
Blazkovec, AA; Miller, FR1
Drevon, C; Kuroki, T; Montesano, R1
Baldwin, RW; Price, MR1
Handler, AH; Homburger, F; Hsueh, SS; Russfield, AB; Soto, E; Van Dongen, CG1
Frantz, CN; Malling, HV1
DiPaolo, JA; Evans, CH; Popescu, NC1
Frei, E; Schroth, P; Wiench, K; Wiessler, M1
Castonguay, A; Goldblatt, PJ; Gunning, WT; Stoner, GD1
Degawa, M; Hashimoto, Y; Miura, S1
Appelkvist, EL; Dallner, G; Kalén, A1
Huang, M; Lindahl, R1
Leach, MF; Lin, KH; Lindahl, R; Winters, AL1
Buchmann, A; Kunz, W; Oesch, F; Robertson, LW; Wolf, CR1
Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM1
Artemova, LG; Pakhomov, VIu; Shuliakovskaia, TS1
Fonshteĭn, LM; Koen, IaM; Loknitskaia, NN; Rykova, VA; Shuliakovskaia, TS1
Buchmann, A; Kunz, W; Oesch, F; Schmitt, R; Schwarz, M; Wolf, CR1
Sivak, A; Tu, AS1
Dietz, D; Kornbrust, D1
Digernes, V; Iversen, OH1
Barbacid, M; DiPaolo, JA; Doniger, J; Evans, CH; Pulciani, S; Sukumar, S; Zbar, B1
Chen, ZF; Gao, WQ; Liu, MQ; Tian, HS; Xiong, YY; Zuo, RD1
Ito, N; Sato, K; Tsuda, H; Yin, Z1
Farmer, PB; Smith, AG; White, IN1
Berberian, I; Chen, LC; Chow, CK; Glauert, HP; Robertson, LW; Robinson, FR1
Kim, HC; Lee, YS; Nishikawa, A1
Joy, KL; Kuttan, G; Kuttan, R1
Anis, KV; Kuttan, R; Rajeshkumar, NV1
Chen, D; Chen, H; Diao, L; Li, H; Liu, M1
Kuttan, R; Rajeshkumar, NV1
Hashimoto, S; Sueishi, K1
Hioki, K; Hirose, M; Ishii, Y; Kanki, K; Kodama, Y; Kuroiwa, Y; Kurokawa, Y; Nishikawa, A; Nomura, T; Umemura, T1
Ao, L; Cao, J; Cui, ZH; Liu, JY; Liu, WB; Yang, H; Zhou, YH; Zhou, ZY1
Ao, L; Cao, J; Cui, ZH; Liu, JY; Liu, WB; Zhou, YH; Zhou, ZY1
Ao, L; Cao, J; Cui, ZH; Liu, JY; Liu, WB; Xiang, YL; Yuan, XY; Zhou, YH; Zhou, ZY2
Blasco, MA; Cañamero, M; Carretero, M; Cuadrado, A; Drosopoulos, WC; Losada, A; Martínez, P; Remeseiro, S; Schildkraut, CL1
Bou-Dargham, MJ; Chen, YH; Etwebi, Z; Goldsmith, JR; Li, M; Li, T; Li, X; Shi, S; Sun, H; Wan, L; Yu, J; Zamani, A; Zhang, L1

Reviews

3 review(s) available for 3-methylcholanthrene and diethylnitrosamine

ArticleYear
Experimental carcinogenesis in small aquarium fishes.
    Progress in experimental tumor research, 1976, Volume: 20

    Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cycasin; Diethylnitrosamine; Dimethylnitrosamine; Female; Fishes; Goldfish; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Sterigmatocystin; Trout

1976
Cell membrane associated antigens in chemical carcinogenesis.
    Biomembranes, 1976, Volume: 8

    Topics: Amines; Animals; Antigens; Antigens, Neoplasm; Azo Compounds; Cell Membrane; Diethylnitrosamine; Embryo, Mammalian; Immunity; Methylcholanthrene; Mice; Neoplasms, Experimental; Rats

1976
[Basic research on lung cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 5

    Topics: Animals; Diethylnitrosamine; Disease Models, Animal; Genes, Tumor Suppressor; Growth Substances; History, 19th Century; History, 20th Century; Humans; Lung Neoplasms; Methylcholanthrene; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogenes; Smoking

2002

Other Studies

39 other study(ies) available for 3-methylcholanthrene and diethylnitrosamine

ArticleYear
Factors influencing the microsome- and mitochondria-catalyzed in vitro binding of diethylnitrosamine and N-nitrosopiperidine to deoxyribonucleic acid.
    Biochemical pharmacology, 1979, Dec-15, Volume: 28, Issue:24

    Topics: Animals; Cytosol; Diethylnitrosamine; DNA; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; NADP; Nitrosamines; Phenobarbital; Piperidines; Rats

1979
Structural limits of specificity of methylcholanthrene-repressible nitrosamine N-dealkylases. Inhibition by analog substrates.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Jun-15, Volume: 86, Issue:2

    Topics: Animals; Binding Sites; Dealkylation; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Repression; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Nitrosamines; Oxidoreductases; Rats

1976
[The tumor-tetanus assay--experimental studies on the biological differentiation between carcinogenesis and organ regeneration of the rat (author's transl)].
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:1

    Topics: Agglutination Tests; Animals; Antibodies, Neoplasm; Antibody Formation; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Cell Survival; Clostridium; Clostridium Infections; Diethylnitrosamine; Liver Neoplasms; Liver Regeneration; Male; Methylcholanthrene; Mice; Neoplasm Transplantation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Sarcoma, Yoshida; Spores, Bacterial; Tetanus

1975
Guinea pig cell-mediated tumor immunity: the chromium release assay detects both cytolysis and serum blocking for syngeneic chemically-induced tumors.
    Immunological communications, 1979, Volume: 8, Issue:1

    Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromium Radioisotopes; Cytotoxicity, Immunologic; Diethylnitrosamine; Fibrosarcoma; Guinea Pigs; Immunity, Cellular; Liver Neoplasms; Lymph Nodes; Lymphocytes; Methylcholanthrene

1979
Microsome-mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Acetonitriles; Animals; Azaguanine; Cell Line; Cell Survival; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Rats; Salmonella typhimurium

1977
Adenocarcinoma of the glandular stomach following 3-methylcholanthrene, N-nitrosodiethylamine, or N-nitrosodimethylamine feeding in carcinogen-susceptible inbred Syrian.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:1

    Topics: Adenocarcinoma; Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Female; Male; Mesocricetus; Methylcholanthrene; Neoplasms, Experimental; Nitrosamines; Species Specificity; Stomach Neoplasms

1976
Factors affecting metabolism and mutagenicity of dimethylnitrosamine and diethylnitrosamine.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: Animals; Carcinogens; Dealkylation; Diethylamines; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Histidine; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Mutagens; Nitrosamines; Phenobarbital; Proadifen; Salmonella typhimurium; Time Factors; Valerates

1975
Chromosome patterns (G and C bands) of in vitro chemical carcinogen-transformed guinea pig cells.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Chromosome Mapping; Chromosomes; Diethylnitrosamine; Methylcholanthrene; Methylnitronitrosoguanidine; Polyploidy

1976
1-C-glucuronidation of N-nitrosodiethylamine and N-nitrosomethyl-n-pentylamine in vivo and in primary hepatocytes from rats pretreated with inducers.
    Carcinogenesis, 1992, Volume: 13, Issue:5

    Topics: Animals; Aroclors; Chromatography, High Pressure Liquid; Diethylnitrosamine; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Organ Specificity; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Urinary Bladder

1992
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
    Toxicologic pathology, 1991, Volume: 19, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylhydrazines; Lung Neoplasms; Methylcholanthrene; Methylnitrosourea; Mice; Mice, Inbred A; Microscopy, Electron; Nitrosamines

1991
Expression and induction of cytochrome P450 isozymes in hyperplastic nodules of rat liver.
    Carcinogenesis, 1991, Volume: 12, Issue:11

    Topics: 2-Acetylaminofluorene; Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Hyperplasia; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; p-Aminoazobenzene; Rats; Rats, Inbred F344

1991
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes.
    Chemico-biological interactions, 1990, Volume: 73, Issue:2-3

    Topics: Animals; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Dolichols; Endoplasmic Reticulum; Intracellular Membranes; Liver; Methylcholanthrene; Mevalonic Acid; Microbodies; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Ubiquinone

1990
Effects of hepatocarcinogenic initiators on aldehyde dehydrogenase gene expression in cultured rat hepatic cells.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Diethylnitrosamine; Enzyme Induction; Ethionine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Methylcholanthrene; Rats; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1990
Characteristics and aldehyde dehydrogenase activity of four rat hepatoma cell lines produced by diethylnitrosamine-phenobarbital treatment.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1986, Volume: 22, Issue:5

    Topics: Aldehyde Dehydrogenase; Animals; Benzo(a)pyrene; Cell Division; Cell Line; Diethylnitrosamine; Enzyme Induction; Female; Isoenzymes; Karyotyping; Liver Neoplasms, Experimental; Methylcholanthrene; NADP; Neoplasm Transplantation; Organoids; Phenobarbital; Phenotype; Rats; Tyrosine Transaminase

1986
Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats.
    Cancer letters, 1986, Volume: 32, Issue:3

    Topics: Animals; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Female; Isoenzymes; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Rats

1986
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:3

    Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344

1987
[Modifying effect of antioxidants on the rate of lipid peroxidation in liver microsomes at early stages of diethylnitrosamine biotransformation].
    Eksperimental'naia onkologiia, 1988, Volume: 10, Issue:5

    Topics: Animals; Antioxidants; Biotransformation; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Drug Interactions; Free Radicals; Lethal Dose 50; Lipid Peroxidation; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Time Factors

1988
[Effect of modifiers of the cytochrome P-450-dependent enzyme system of the liver on the metabolic pathways of diethylnitrosamine activation and inactivation].
    Voprosy onkologii, 1987, Volume: 33, Issue:1

    Topics: Animals; Antioxidants; Cytochrome P-450 Enzyme System; Diethylnitrosamine; In Vitro Techniques; Kinetics; Lethal Dose 50; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium

1987
Development of cytochrome P-450-altered preneoplastic and neoplastic lesions during nitrosamine-induced hepatocarcinogenesis in the rat.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Animals; Cell Differentiation; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Isoenzymes; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Phenobarbital; Precancerous Conditions; Rats

1987
Use of rodent hepatocytes for metabolic activation in transformation assays.
    IARC scientific publications, 1985, Volume: 67

    Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Liver; Methylcholanthrene; Mice; Phenobarbital; Rats; Species Specificity

1985
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
    Chemico-biological interactions, 1985, Dec-17, Volume: 56, Issue:1

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains

1985
Increased epidermal DT-diaphorase activity induced by some carcinogens. A possible mechanism explaining the tetrazolium reduction test (TZT) for skin carcinogens--a preliminary report.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1981, Volume: 36, Issue:2-3

    Topics: Acetone; Animals; Anthracenes; Carcinogens; Diethylnitrosamine; Epidermis; Female; Male; Methylcholanthrene; Methylnitrosourea; Mice; Mice, Nude; NADH, NADPH Oxidoreductases; Quinone Reductases; Tetradecanoylphorbol Acetate; Tetrazolium Salts

1981
A transforming ras gene in tumorigenic guinea pig cell lines initiated by diverse chemical carcinogens.
    Science (New York, N.Y.), 1984, Mar-16, Volume: 223, Issue:4641

    Topics: Animals; Base Sequence; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA Restriction Enzymes; Gene Expression Regulation; Genes, Viral; Guinea Pigs; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Oncogenes; Retroviridae

1984
Induction of lung carcinoma by intralobar bronchial instillation of iodized oil in rats.
    Chinese medical journal, 1984, Volume: 97, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Iodized Oil; Lung Neoplasms; Male; Methylcholanthrene; Nitrosamines; Rats; Rats, Inbred Strains

1984
Changes in activities of uridine diphosphate-glucuronyltransferases during chemical hepatocarcinogenesis.
    Gan, 1982, Volume: 73, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxyanisole; Diethylnitrosamine; Enzyme Induction; Glucuronosyltransferase; Hyperplasia; Liver; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; Rats; Rats, Inbred Strains

1982
Formation of N-alkylated protoporphyrin IX in the livers of mice after diethylnitrosamine treatment.
    The Biochemical journal, 1983, Jun-15, Volume: 212, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Liver; Male; Mass Spectrometry; Methylcholanthrene; Mice; Mice, Inbred C57BL; Nitrosamines; Phenobarbital; Porphyrins; Protoporphyrins

1983
Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamine.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Body Weight; Cell Division; Cocarcinogenesis; Diethylnitrosamine; Diterpenes; Drug Interactions; Female; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Polychlorinated Biphenyls; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A

1995
Enhancing effects of phenobarbital and 3-methylcholanthrene on GST-P-positive liver cell foci development in a new medium-term rat liver bioassay using D-galactosamine.
    Journal of toxicology and environmental health, 1997, Apr-11, Volume: 50, Issue:5

    Topics: Animals; Biological Assay; Blood Chemical Analysis; Body Weight; Carcinogens; Diet; Diethylnitrosamine; Galactosamine; Glutathione Transferase; Injections, Intraperitoneal; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylcholanthrene; Organ Size; Phenobarbital; Rats; Rats, Inbred F344

1997
Antioxidant and anticarcinogenic activity of Lycovin--an indigenous herbal preparation.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Diethylnitrosamine; In Vitro Techniques; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Mice; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species; Sarcoma, Experimental

1999
Inhibition of chemical carcinogenesis by berberine in rats and mice.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:5

    Topics: Alkylating Agents; Animals; Berberine; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationship, Drug; Female; Lipid Peroxidation; Liver; Liver Neoplasms; Methylcholanthrene; Mice; Neoplasms, Experimental; Plant Extracts; Rats; Rats, Wistar; Sarcoma

2001
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2002, Volume: 24, Issue:2

    Topics: Alkylating Agents; Animals; Carcinoma, Squamous Cell; Diethylnitrosamine; Female; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Methylcholanthrene; Neoplasm Invasiveness; Neoplasm Metastasis; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2

2002
Cancare-a herbal formulation inhibits chemically induced tumours in experimental animals.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:7

    Topics: Animals; Diethylnitrosamine; Female; Liver Neoplasms, Experimental; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phytotherapy; Plant Preparations; Rats; Rats, Wistar; Sarcoma, Experimental

2001
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
    Cancer letters, 2006, Jan-18, Volume: 231, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Humans; Incidence; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Transgenic; Oncogene Protein p21(ras)

2006
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
    Toxicology letters, 2009, Aug-25, Volume: 189, Issue:1

    Topics: Animals; Azacitidine; Cell Line; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Diethylnitrosamine; DNA Methylation; Female; Immunohistochemistry; Lung; Lung Neoplasms; Male; Methylcholanthrene; Microdissection; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

2009
Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer.
    Molecular carcinogenesis, 2010, Volume: 49, Issue:6

    Topics: Animals; Carcinoma; Cell Cycle; CpG Islands; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Diethylnitrosamine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Male; Methylcholanthrene; Promoter Regions, Genetic; Rats; Rats, Wistar

2010
CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
    Biochemical and biophysical research communications, 2010, Nov-19, Volume: 402, Issue:3

    Topics: Acid Anhydride Hydrolases; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; CpG Islands; Death-Associated Protein Kinases; Diethylnitrosamine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Lung Neoplasms; Male; Methylcholanthrene; Neoplasm Proteins; Rats; Rats, Wistar; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Tumor Suppressor Proteins

2010
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
    Toxicology and applied pharmacology, 2011, Feb-15, Volume: 251, Issue:1

    Topics: Animals; Azacitidine; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Decitabine; Diethylnitrosamine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Female; Gene Silencing; Immunoglobulins; Lung Neoplasms; Male; Methylcholanthrene; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-3; Up-Regulation

2011
Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.
    The EMBO journal, 2012, May-02, Volume: 31, Issue:9

    Topics: Aneuploidy; Animals; Carcinogens; Cell Cycle Proteins; Cell Line; Chromatids; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Cohesins; Diethylnitrosamine; Fibrosarcoma; Liver Neoplasms; Male; Methylcholanthrene; Mice; Mice, Knockout; Neoplasms, Experimental; Protein Subunits; Sister Chromatid Exchange; Telomere

2012
Decoupling tumor cell metastasis from growth by cellular pilot protein TNFAIP8.
    Oncogene, 2021, Volume: 40, Issue:46

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diethylnitrosamine; Female; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Hippo Signaling Pathway; Humans; Lung Neoplasms; Male; Methylcholanthrene; Mice; Phosphatidylinositol 3-Kinases; Skin Neoplasms

2021