3-methylcholanthrene has been researched along with dactinomycin in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (91.04) | 18.7374 |
| 1990's | 3 (4.48) | 18.2507 |
| 2000's | 2 (2.99) | 29.6817 |
| 2010's | 1 (1.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Raw, I; Rockwell, P | 1 |
| Freeman, AE; Gilden, RV; Hatanaka, M; Huebner, RJ; Tsuchida, N | 1 |
| Seifert, J; Vácha, J | 1 |
| Alvares, AP; Kappas, A | 1 |
| Benedict, WF; Brandt, KR; Curren, RD; Henry, CJ; Kouri, RE; Rude, TH; Schechtman, LM; Sosnowski, RG | 1 |
| Parke, DV; Poole, TW | 1 |
| Hong, SL; Levine, L; Pong, SS | 1 |
| Bridges, JW; McPherson, FJ; Parke, DV | 1 |
| Breuer, H; Haueter, G; Rao, GS; Rao, ML | 1 |
| Nemoto, N; Sakurai, J | 1 |
| Doerr, CL; Harrington-Brock, K; Moore, MM | 1 |
| Al-Turk, WA; Hassing, JM; Stohs, SJ | 1 |
| Kuroiwa, Y; Numazawa, S; Oguro, T; Yoshida, T | 1 |
| Batel, R; Bihari, N; Zahn, RK | 1 |
| Bonkovsky, HL; Healey, JF; Lincoln, BC | 1 |
| Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G | 1 |
| Barski, G; Belehradek, J; Biedler, JL; Thonier, M | 1 |
| Bates, R; Gelboin, HV | 1 |
| Gelboin, HV | 3 |
| Akamatsu, Y; Haruta, M; Ikegami, R | 1 |
| Burgison, RM; Dietz, AJ | 1 |
| Alvares, AP; Bickers, DR; Kappas, A | 1 |
| Deb, C; Hanker, JS; Morizono, Y; Seligman, AM; Zenker, N | 1 |
| Morris, HP; Potter, VR; Watanabe, M | 1 |
| Fridlianskaia, II; Khodosova, IA | 1 |
| Mallucci, L; Poste, GH; Wells, V | 1 |
| Poste, G | 1 |
| Alexander, DJ; Greenham, LW; Mallucci, L; Poste, G; Reeve, P | 1 |
| Keller, R | 1 |
| Brodeur, J; Gascon, AL | 1 |
| Burkhalter, A; Howland, RD | 1 |
| Cavallito, J; Loh, A; Welch, RM | 1 |
| Nagata, C | 1 |
| Khodosova, IA | 1 |
| Christoffersen, T; Jervell, KF; Mörland, J | 1 |
| Matumoto, M; Toba, M | 1 |
| Cloutier, G; Gascon, AL | 1 |
| Arcos, JC; Argus, MF; Venkatesan, N | 2 |
| Fouts, JR; Stock, BH | 1 |
| Alvares, AP; Kuntzman, R; Schilling, G | 1 |
| Weisburger, EK; Weisburger, JH; Yamamoto, RS | 1 |
| Alvares, AP; Kuntzman, R; Levin, W; Schilling, G | 1 |
| Baserga, R; McDonough, M; Sasaki, T; Shimkin, MB; Thatcher, D; Wieder, R | 1 |
| Lasnitzki, I | 1 |
| Frenster, JH | 1 |
| Dao, TL; Varela, RM | 1 |
| Bresnick, E | 1 |
| Enomoto, M; Lotlikar, PD; Miller, EC; Miller, JA | 1 |
| Blake, DA; Cascorbi, HF; Krantz, JC; Rozman, RS | 1 |
| Bertram, JS; Libby, PR; Merriman, RL | 1 |
| Ishidate, K; Nakazawa, Y; Tsuruoka, M | 1 |
| Kleeberg, U; Klinger, W | 1 |
| Lin, KH; Lindahl, R; Winters, AL | 1 |
| Beil, W; Kahl, GF; Kahl, R | 1 |
| Artur, Y; Desvergne, B; Goudonnet, H; Hihi, AK; Masmoudi, T; Vázquez, M; Wahli, W | 1 |
| Giannone, JV; Li, W; Okey, AB; Probst, M | 1 |
| Edwards, RJ; Guengerich, FP; Hollenberg, PF; Kim, H; Novak, RF; Putt, DA; Wolf, CR; Zangar, RC | 1 |
| Ho, JW; Leung, YK | 1 |
| BLACKBURN, NR; GELBOIN, HV | 2 |
| STANCEK, D; VILCEK, J | 1 |
| DUBOIS, KP; KINOSHITA, F | 1 |
| BUSCH, GJ; OWENS, AH | 1 |
3 review(s) available for 3-methylcholanthrene and dactinomycin
| Article | Year |
|---|---|
Studies on the mechanism of microsomal hydroxylase induction and its role in carcinogen action.
Topics: Animals; Anthracenes; Benz(a)Anthracenes; Carbon Isotopes; Carcinogens; Cells, Cultured; Cricetinae; Cytidine; Dactinomycin; Electrophoresis; Enzyme Induction; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms; Phenobarbital; Protein Biosynthesis; Rats; RNA; RNA Nucleotidyltransferases; Tritium; Uridine | 1972 |
[Interaction between chemical carcinogens and nucleic acids. 1. Theoretical basis of carcinogenesis].
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Chemical Phenomena; Chemistry; Dactinomycin; DNA; Humans; Methylcholanthrene; Neoplasms, Experimental; Nucleic Acids; Nucleotides; Spectrum Analysis | 1970 |
[Mechanisms of chemical carcinogenesis].
Topics: Aflatoxins; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Nucleolus; Cell Nucleus; Cricetinae; Culture Techniques; Dactinomycin; DNA; Ethionine; Liver; Methylcholanthrene; Mice; Nitrosourea Compounds; Rats; RNA; Skin; Urethane | 1971 |
64 other study(ies) available for 3-methylcholanthrene and dactinomycin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Effect of a single dose of inducers and inhibitors on the rate of synthesis of cytochromes and reductases in liver organelles.
Topics: Aflatoxins; Animals; Chloramphenicol; Cycloheximide; Cytochrome Reductases; Cytochromes; Dactinomycin; Female; Liver; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Rabbits | 1979 |
Type-C virus-specific nucleic acid sequences in cultured rat cells.
Topics: Amino Acid Sequence; Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Culture Media; Dactinomycin; Depression, Chemical; DNA, Viral; Methylcholanthrene; Mice; Mice, Inbred BALB C; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Retroviridae; RNA, Viral; Stimulation, Chemical; Tritium; Virus Replication | 1975 |
Microsomal inducers of drug-metabolizing enzymes suppress cytidine nucleotide biosynthesis in rat liver.
Topics: Animals; Antimetabolites; Azauridine; Barbiturates; Benzopyrenes; Carbon Tetrachloride; Colchicine; Cycloheximide; Cytarabine; Cytosine Nucleotides; Dactinomycin; DDT; Hydrocortisone; Liver; Male; Methylcholanthrene; Microsomes, Liver; Orotic Acid; Puromycin; Rats; Spermidine | 1975 |
The inducing properties of polychlorinated biphenyls on hepatic monooxygenases.
Topics: Animals; Aroclors; Cytochromes; Dactinomycin; Enzyme Induction; Female; In Vitro Techniques; Liver; Maternal-Fetal Exchange; Methylcholanthrene; Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Pregnancy; Rats | 1977 |
Biological activity of tobacco smoke and tobacco smoke-related chemicals.
Topics: Animals; Carcinogens; Cycloheximide; Dactinomycin; Lung; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes; Mutagens; Nicotiana; Plants, Toxic; Rats; Salmonella; Smoking | 1979 |
Effect of protein synthesis inhibitors on the induction of rat liver microsomal cytochrome P-448 by 3-methylcholanthrene [proceedings].
Topics: Amanitins; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Rats | 1979 |
Prostaglandin production by methylcholanthrene-transformed mouse BALB/3T3. Requirement for protein synthesis.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acids; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Dactinomycin; Emetine; Kinetics; Methylcholanthrene; Mice; Prostaglandins; Prostaglandins E; Prostaglandins F; Protein Biosynthesis; Tosyl Compounds; Transcription, Genetic | 1977 |
The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes.
Topics: Acetone; Aniline Hydroxylase; Animals; Benzopyrene Hydroxylase; Benzopyrenes; Catechol Oxidase; Cricetinae; Cytochromes; Dactinomycin; Dioxoles; Male; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nikethamide; Phenobarbital; Rats; Safrole | 1976 |
Steroid glucuronyltransferases of rat liver. Properties of oestrone and testosterone glucuronyltransferases and the effect of ovariectomy, castration and administration of steroids on the enzymes.
Topics: Animals; Bilirubin; Castration; Cycloheximide; Dactinomycin; Detergents; Estradiol; Estrone; Female; Glucuronates; Hexosyltransferases; Kinetics; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Rats; Testosterone | 1977 |
Altered regulation of Cyp1a-1 gene expression during cultivation of mouse hepatocytes in primary culture.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Female; Gene Expression Regulation; Liver; Methylcholanthrene; Mice; Mice, Inbred C57BL; Time Factors | 1992 |
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrations; Dactinomycin; Dimethyl Sulfoxide; DNA Damage; Doxorubicin; Hazardous Waste; Leukemia L5178; Leukemia, Experimental; Methylcholanthrene; Methylmethacrylate; Methylmethacrylates; Mice; Micronucleus Tests; Mutation; Nitrogen Mustard Compounds; Proflavine; Thymidine Kinase | 1989 |
Influence of protein and RNA synthesis inhibitors on methylcholanthrene-mediated induction of aryl hydrocarbon hydroxylase activity in intestinal mucosa.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cycloheximide; Dactinomycin; Deoxyadenosines; Enzyme Induction; In Vitro Techniques; Intestinal Mucosa; Leucine; Male; Methylcholanthrene; Microsomes; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA | 1988 |
Induction of ornithine decarboxylase and S-adenosylmethionine decarboxylase by sulfobromophthalein in rats.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glutathione; Kinetics; Liver; Male; Methylcholanthrene; Ornithine Decarboxylase; Phenobarbital; Polyamines; Rats; Rats, Inbred Strains; Sulfobromophthalein | 1989 |
3-Methylcholanthrene does induce mixed function oxidase activity in hepatopancreas of spiny crab Maja crispata.
Topics: Animals; Brachyura; Cycloheximide; Dactinomycin; Enzyme Induction; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Pancreas; Protein Biosynthesis; Transcription, Genetic | 1988 |
Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Glutethimide; Heme; Heme Oxygenase (Decyclizing); Liver; Mephenytoin; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Porphyrins | 1988 |
Microsomal phospholipids and drug action--quantitative biochemical and electron microscopic studies.
Topics: Animals; Carbon Tetrachloride; Choline; Coumarins; Dactinomycin; Endoplasmic Reticulum; Ethanol; Ethionine; Female; Glucose-6-Phosphatase; Hexobarbital; Histocytochemistry; In Vitro Techniques; Male; Methylcholanthrene; Microscopy, Electron; Microsomes, Liver; Nitrosamines; Phenobarbital; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats | 1972 |
Actinomycin-D-resistant in vitro mouse cell line derived from a methylcholanthrene-induced sarcoma: decrease of malignancy and antigenic characteristics.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cricetinae; Cross Reactions; Dactinomycin; Drug Resistance; Epitopes; Female; Fluorescent Antibody Technique; Goats; Immune Sera; Immunity, Cellular; In Vitro Techniques; Karyotyping; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sarcoma, Experimental; Transplantation, Heterologous; Transplantation, Homologous | 1974 |
Genetic regulatory mechanisms and carcinogenesis.
Topics: Animals; Anthracenes; Benzopyrenes; Dactinomycin; Genetic Code; Humans; Methylcholanthrene; Neoplasms; Rats; RNA, Messenger | 1966 |
Carcinogenesis and gene action. Franz Bielschowsky Memorial Lecture.
Topics: Animals; Azo Compounds; Carcinogens; Dactinomycin; DNA; Enzyme Induction; Genes; Liver; Methylcholanthrene; Mixed Function Oxygenases; Molecular Biology; Neoplasms; Neoplasms, Experimental; Phenobarbital; Phenotype; Puromycin; Rats; RNA; RNA Nucleotidyltransferases | 1968 |
Subcutaneous sarcomas induced by mitomycin C in mice: comparisons of occurrence, transplantability and histology between sarcomas induced by actinomycin S and 3-methylcholanthrene.
Topics: Animals; Carcinogens; Dactinomycin; Injections, Subcutaneous; Male; Methylcholanthrene; Mice; Mitomycins; Neoplasm Transplantation; Sarcoma, Experimental; Sodium Chloride | 1967 |
The biotransformation of 8-ethylthio-6-thiotheophylline sodium in vivo.
Topics: Amines; Animals; Carbon Tetrachloride; Chromatography, Thin Layer; Dactinomycin; Depression, Chemical; Hypnotics and Sedatives; Male; Methylcholanthrene; Oils; Phenobarbital; Proadifen; Rats; Sleep; Stimulation, Chemical; Theophylline; Time Factors | 1968 |
Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Enzyme Induction; Ligands; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Biphenyls; Rats; Spectrophotometry; Stimulation, Chemical | 1973 |
Carcinogens 3,4-benzpyrene and 3-methylcholanthrene: induction of mitochondrial oxidative enzymes.
Topics: Animals; Benzopyrenes; Dactinomycin; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Enzyme Induction; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenase; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Methylcholanthrene; Mitochondria, Liver; Phenobarbital; Rats; Stimulation, Chemical; Succinate Dehydrogenase; Tetrazolium Salts; Triiodothyronine | 1968 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; Puromycin; Rats | 1970 |
[Effect of 20-methylcholanthrene on the activity of some enzymes in normal cell cultures].
Topics: Animals; Animals, Newborn; Aspartate Aminotransferases; Cell Line; Culture Techniques; Dactinomycin; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphatase; Methylcholanthrene; Mice; Puromycin; Rhabdomyosarcoma | 1971 |
Synthesis of cell coat in normal and transformed cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cycloheximide; Dactinomycin; Glycoproteins; Kinetics; Leucine; Methylcholanthrene; Mice; Neoplasms, Experimental; Polyomavirus; RNA, Neoplasm; Tritium | 1972 |
The synthesis of surface coat materials in normal and transformed cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cricetinae; Cycloheximide; Dactinomycin; Fibroblasts; Gammaretrovirus; Kidney; Methylcholanthrene; Mice; Polyomavirus; RNA, Messenger; RNA, Neoplasm; Simian virus 40; Surface Properties; Time Factors | 1973 |
The study of cellular "microexudates" by ellipsometry and their relationship to the cell coat.
Topics: Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Cycloheximide; Cytological Techniques; Dactinomycin; Fibroblasts; HeLa Cells; L Cells; Leucine; Methylcholanthrene; Polyomavirus; Temperature; Tritium | 1973 |
Mechanisms by which activated normal macrophages destroy syngeneic rat tumour cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of metabolic inhibitors.
Topics: Agglutination; Animals; Antimetabolites; Benz(a)Anthracenes; Cell Aggregation; Cells, Cultured; Cycloheximide; Cytochalasin B; Dactinomycin; DNA; Enzymes; Guinea Pigs; Immune Tolerance; Kinetics; Macrophages; Methylcholanthrene; Neoplasms, Experimental; Polyomavirus; Rats; Silicon Dioxide; T-Lymphocytes; Thymidine; Time Factors; Tritium | 1974 |
Influence of microsomal enzyme inducers on the reactivity of the isolated guinea pig seminal vesicle to angiotensin and tyramine.
Topics: Angiotensin II; Animals; Aspirin; Dactinomycin; DDT; Drug Antagonism; Enzyme Induction; Glutethimide; Guinea Pigs; Male; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Piperazines; Proadifen; Protein Biosynthesis; Seminal Vesicles; Sulfanilamides; Tyramine | 1969 |
Some effects of 3-methylcholanthrene on uridine diphosphate glucuronyltransferase in the rat and guinea pig.
Topics: Animals; Dactinomycin; Enzyme Induction; Ethionine; Glucuronates; Glucuronosyltransferase; Guinea Pigs; Hexosyltransferases; Hydrocarbons; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Magnesium; Male; Methylcholanthrene; Microsomes, Liver; Nikethamide; Nucleoside Diphosphate Sugars; Phenobarbital; Phenols; Piperazines; Protein Biosynthesis; Rats; Time Factors; Uracil Nucleotides | 1971 |
Effect of exposure to cigarette smoke on the metabolism of benzo(a)pyrene and acetophenetidin by lung and intestine of rats.
Topics: Animals; Benzopyrenes; Carbon Isotopes; Dactinomycin; Enzyme Induction; Female; Hydrocarbons; Intestinal Mucosa; Intestines; Kinetics; Liver; Lung; Male; Methylcholanthrene; Mixed Function Oxygenases; Nicotiana; Phenacetin; Plants, Toxic; Pregnancy; Puromycin; Rats; Smoking; Time Factors | 1972 |
Studies on the 3-methylcholanthrene induction and carbohydrate repression of rat liver dimethylaminoazobenzene reductase.
Topics: Animals; Dactinomycin; Enzyme Repression; Ethionine; In Vitro Techniques; Liver; Methylcholanthrene; Orotic Acid; Oxidoreductases; p-Dimethylaminoazobenzene; Rats; RNA | 1965 |
Mechanism of enhancement of Newcastle disease virus growth in cultured cells by co-infecting hog cholera virus.
Topics: Adsorption; Animals; Biological Assay; Cells, Cultured; Chick Embryo; Classical Swine Fever; Culture Techniques; Cytopathogenic Effect, Viral; Dactinomycin; Encephalitis Virus, Western Equine; Immune Sera; Interferons; Male; Methylcholanthrene; Neutralization Tests; Newcastle disease virus; Rabbits; Swine; Testis; Time Factors; Virus Replication; Viruses, Unclassified | 1971 |
Modification of catecholamine content of male accessory sexual tissues of guinea pig after pretreatment with microsomal enzyme inducers.
Topics: Adrenal Glands; Animals; Brain; Castration; Catecholamines; Dactinomycin; DDT; Epinephrine; Guinea Pigs; Male; Methylcholanthrene; Norepinephrine; Pargyline; Phenobarbital; Proteins; Seminal Vesicles; Testis; Vas Deferens | 1971 |
Mechanism of 3-methylcholanthrene-induced inhibition of dimethylnitrosamine demethylase in rat liver.
Topics: Animals; Dactinomycin; Female; Kinetics; Liver; Male; Methylcholanthrene; Methyltestosterone; Microsomes, Liver; Nitrosamines; Oxidoreductases; Phenobarbital; Puromycin; Rats; Sex Factors; Time Factors | 1970 |
Amino acid induction and carbohydrate repression of dimethylnitrosamine demethylase in rat liver.
Topics: Animals; Caseins; Cellulose; Dactinomycin; Diet; Enzyme Induction; Enzyme Repression; Glucose; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases; Rats; Starvation | 1970 |
The influence of in vivo administration of dimethyl sulfoxide on the in vitro metabolism of some monocyclic aromatic chemicals by hepatic microsomal preparations.
Topics: Acetanilides; Aniline Compounds; Animals; Anisoles; Biotransformation; Cycloheximide; Cytochromes; Dactinomycin; Dimethyl Sulfoxide; Female; In Vitro Techniques; Male; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Phenobarbital; Rabbits; Rats; Stimulation, Chemical | 1971 |
Alteration in the microsomal hemoprotein and the kinetics of 3,4-benzpyrene hydroxylase induced by 3-methylcholanthrene: time course study and effects of puromycin.
Topics: Animals; Blood Proteins; Dactinomycin; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Puromycin; Rats; Spectrum Analysis; Time Factors | 1971 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Organ Size; Phenobarbital; Phenothiazines; Proadifen; Puromycin; Urethane | 1971 |
Alteration of the microsomal hemoprotein by 3-methylcholanthrene: effects of ethionine and actinomycin D.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochromes; Dactinomycin; Enzyme Induction; Ethionine; Liver; Male; Methionine; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Phenobarbital; Rats; Solubility; Spectrophotometry | 1968 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Lung Neoplasms; Male; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms, Experimental; Puromycin; Thymidine; Tritium; Urethane | 1969 |
The effects of actinomycin D and methylcholanthrene on the cytology and RNA and protein synthesis in prostatic epithelium grown in vitro.
Topics: Animals; Cell Nucleus; Culture Techniques; Dactinomycin; Epithelium; Hyperplasia; Leucine; Male; Methylcholanthrene; Precancerous Conditions; Prostate; Protein Biosynthesis; Rats; RNA; Time Factors; Tritium; Uridine | 1969 |
Correlation of the binding to DNA loops or to DNA helices with the effect on RNA synthesis.
Topics: Acridines; Chloroquine; Dactinomycin; DNA; Estradiol; Histones; Lysine; Methylcholanthrene; Nucleotidyltransferases; Protein Binding; RNA; Testosterone | 1965 |
On the mechanism of inducing protection of the adrenal cortex against injury from 7,12-dimethylbenz(a)anthracene. I. Effects of inducers on benzpyrene hydroxylase activity.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Benzopyrenes; Dactinomycin; Ethionine; Female; Hydrocarbons; Hydrolases; In Vitro Techniques; Intestine, Small; Liver; Mammary Glands, Animal; Methylcholanthrene; Puromycin; Rats | 1966 |
Ribonucleic acid polymerase activity in liver nuclei from rats pretreated with 3-methylcholanthrene.
Topics: Animals; Antifungal Agents; Cell Nucleus; Cycloheximide; Dactinomycin; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nucleotidyltransferases; Quaternary Ammonium Compounds; Rats; RNA | 1966 |
Species variations in the N- and ring-hydroxylation of 2-acetylaminofluorene and effects of 3-methylcholanthrene pretreatment.
Topics: Animals; Biological Assay; Carcinogens; Cricetinae; Dactinomycin; Fluorenes; Guinea Pigs; Liver; Male; Methylcholanthrene; Mice; Microsomes; Puromycin; Rabbits; Rats | 1967 |
Anesthesia. LXXIV. Biotransformation of fluroxene. I. Metabolism in mice and dogs in vivo.
Topics: Animals; Benzopyrenes; Biotransformation; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Dactinomycin; Dogs; Ethers; Ethyl Ethers; Ethylamines; Female; Male; Methylcholanthrene; Mice; Nitrous Oxide; Phenobarbital; Proadifen | 1967 |
Modulation of carcinogen-induced transformation by actinomycin D in the C3H/10T 1/2 cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dactinomycin; Enzyme Induction; Methylcholanthrene; Mice; Mice, Inbred C3H; RNA | 1980 |
Induction of choline kinase by polycyclic aromatic hydrocarbon carcinogens in rat liver.
Topics: Animals; Carcinogens; Choline Kinase; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phosphotransferases; Polycyclic Compounds; Rats | 1980 |
Glucose-6-phosphatase activities in the developing rat liver and kidney and after phenobarbital, 3-methylcholanthrene, and actinomycin D pretreatment.
Topics: Aging; Animals; Animals, Laboratory; Animals, Newborn; Dactinomycin; Glucose-6-Phosphatase; Kidney; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Regulation of aldehyde dehydrogenase activity in five rat hepatoma cell lines.
Topics: Aldehyde Dehydrogenase; Amanitins; Animals; Benzo(a)pyrene; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Kinetics; Liver Neoplasms, Experimental; Methylcholanthrene; Phenotype; Rats | 1984 |
Circadian rhythm of the inhibitory effect of actinomycin D on cytochrome P-448 induction by 3-methylcholanthrene.
Topics: Animals; Circadian Rhythm; Cycloheximide; Cytochrome P-450 CYP1A2; Cytochromes; Dactinomycin; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Rats; Transcription, Genetic | 1980 |
Transcriptional regulation by triiodothyronine of the UDP-glucuronosyltransferase family 1 gene complex in rat liver. Comparison with induction by 3-methylcholanthrene.
Topics: Animals; Carcinogens; Cycloheximide; Dactinomycin; Enzyme Induction; Glucuronosyltransferase; Liver; Methylcholanthrene; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Triiodothyronine | 1997 |
Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Cell Line; Cell Nucleus; Cytosol; Dactinomycin; DNA Primers; DNA-Binding Proteins; Kinetics; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; RNA, Messenger; Transcription Factors; Transcription, Genetic | 1998 |
Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Clofibrate; Cycloheximide; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dactinomycin; Deoxyadenosines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Isoenzymes; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Alignment; Transcription, Genetic | 2001 |
Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Hepatocellular; Dactinomycin; Glucuronosyltransferase; Methylcholanthrene; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
THE STIMULATORY EFFECT OF 3-METHYLCHOLANTHRENE ON MICROSOMAL AMINO ACID INCORPORATION AND BENZPYRENE HYDROXYLASE ACTIVITY AND ITS INHIBITION BY ACTINOMYCIN D.
Topics: Amino Acids; Benzopyrenes; Carbon Isotopes; Dactinomycin; Liver; Methylcholanthrene; Mixed Function Oxygenases; Phenylalanine; Proteins; Rats; Research; Ribonucleases; RNA; Uracil Nucleotides | 1963 |
UNRESPONSIVENESS TO THE ACTION OF INTERFERON DEVELOPED IN PERSISTENTLY INFECTED L CELLS.
Topics: Dactinomycin; Encephalitis Viruses; Interferons; Methylcholanthrene; Research; Research Design; Tissue Culture Techniques; Virus Cultivation | 1963 |
THE STIMULATORY EFFECT OF 3-METHYLCHOLANTHRENE ON BENZPYRENE HYDROXYLASE ACTIVITY IN SEVERAL RAT TISSUES: INHIBITION BY ACTINOMYCIN D AND PUROMYCIN.
Topics: Anti-Bacterial Agents; Benzopyrenes; Dactinomycin; DNA; Metabolism; Methylcholanthrene; Mixed Function Oxygenases; Neoplasms; Pharmacology; Puromycin; Rats; Research; RNA | 1964 |
THE EFFECTS OF IONIZING RADIATIONS ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. I. THE INFLUENCE OF X-IRRADIATION AND CHEMICAL AGENTS ON DETOXIFICATION MECHANISMS. QUART PROGR REP 49.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzopyrenes; Dactinomycin; Liver; Methylcholanthrene; Nikethamide; Organophosphate Poisoning; Pharmacology; Phenobarbital; Phosphorus; Poisons; Puromycin; Radiation Injuries; Radiation Injuries, Experimental; Radiation, Ionizing; Rats; Research; Toxicology | 1963 |
STUDIES ON THE MECHANISM OF METHYLCHOLANTHRENE INDUCTION OF ENZYME ACTIVITIES. II. STIMULATION OF MICROSOMAL AND RIBOSOMAL AMINO ACID INCORPORATION: THE EFFECTS OF POLYURIDYLIC ACID AND ACTINOMYCIN-D.
Topics: Amino Acids; Antimetabolites; Dactinomycin; Leucine; Liver; Magnesium; Methylcholanthrene; Microsomes; Phenylalanine; Poly U; Rats; Research; Ribonucleases; Ribosomes; RNA; Uracil Nucleotides | 1964 |
THE UTILITY OF A CARCINOGEN-INDUCED RAT MAMMARY CANCER AS A CHEMOTHERAPEUTIC SCREENING DEVICE.
Topics: Animals; Breast Neoplasms; Carcinogens; Cyclophosphamide; Dactinomycin; Diet; Diet Therapy; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mechlorethamine; Mercaptopurine; Methotrexate; Methylcholanthrene; Neoplasms; Rats; Research; Toxicology | 1965 |