3-methylcholanthrene and cyanides

3-methylcholanthrene has been researched along with cyanides in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199025 (96.15)18.7374
1990's1 (3.85)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mannering, GJ; Peisach, J1
Kahl, GF; Kahl, R; Kumaki, K; Nebert, DW1
Brühl, R; Rupec, M1
Gaylor, JL; Morris, HP; Williams, MT1
Levin, W; Lu, AY; Ryan, D; West, S1
Kanakubo, Y; Kitada, M; Rikihisa, T; Sakamoto, K1
Kuwahara, S; Mannering, GJ1
Mannering, GJ1
Gangolli, S; Wright, M1
Correia, MA; Mannering, GJ1
Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ1
O'Brien, PJ; Rahimtula, AD1
Mannering, GJ; Parli, CJ1
Conney, AH; Kuntzman, R; Lu, AY; Somogyi, A; West, S1
Levin, W; Lu, AY; Ryan, D; Vore, M; West, SB1
Alvares, AP; Kuntzman, R; Levin, W; Schilling, G1
Mannering, GJ; Zampaglione, NG1
Comai, K; Gaylor, JL1
Glover, E; Poland, A1
Alvares, AP; Conney, AH; Gommi, B; Welch, RM1
Nery, R1
Mannering, GJ; Sladek, NE2
Calabrese, RL; Gaylor, JL; Jefcoate, CR1
Chiba, K; Imai, Y; Kamataki, T; Kitada, M; Kitagawa, H; Sato, R1
Abdel-Aziz, AH; Abdel-Naim, AB; Abo-Salem, O; Hamada, FM; Mostafa, AM1

Other Studies

26 other study(ies) available for 3-methylcholanthrene and cyanides

ArticleYear
A re-evaluation of the optical titrations of the 430 and 455 nm chromophore of ethyl isocyanide complexes of mamalian hepatic cytochrome P-450.
    Molecular pharmacology, 1975, Volume: 11, Issue:6

    Topics: Animals; Chromatophores; Computers; Cyanides; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry

1975
Association of the Ah locus with specific changes in metyrapone and ethylisocyanide binding to mouse liver microsomes.
    The Journal of biological chemistry, 1976, Sep-10, Volume: 251, Issue:17

    Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Enzyme Induction; Genes, Dominant; Hydrogen-Ion Concentration; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mutation; Oxygenases; Phenobarbital; Protein Binding; Protein Conformation; Spectrophotometry

1976
On the question of the ultrastructure and composition of corpus intra cristam after local methylcholanthrene application.
    Journal of ultrastructure research, 1976, Volume: 54, Issue:3

    Topics: Animals; Cyanides; Electron Transport Complex IV; Inclusion Bodies; Membranes; Methylcholanthrene; Mice; Mitochondria; Pronase; Skin

1976
Characterization of microsomal methyl sterol demethylase in two Morris hepatomas.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Animals; Buffers; Carcinoma, Hepatocellular; Cholesterol; Cholestyramine Resin; Cyanides; Cytochrome c Group; Diphosphates; Edetic Acid; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Neoplasms, Experimental; Phenobarbital; Phosphates; Rats; Steroid Hydroxylases; Sterols

1976
Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.
    The Journal of biological chemistry, 1975, Mar-25, Volume: 250, Issue:6

    Topics: Amines; Animals; Benzopyrenes; Benzphetamine; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Hemeproteins; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Protein Conformation; Rats; Spectrophotometry

1975
Different effects of cyanide on the activities of 7-ethoxycoumarin O-deethylation catalyzed by two forms of cytochrome P-450 purified from 3-methylcholanthrene-treated rats.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Catalysis; Cyanides; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxygen; Oxygenases; Potassium Cyanide; Rats; Rats, Inbred Strains

1985
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
    Biochemical pharmacology, 1985, Dec-15, Volume: 34, Issue:24

    Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats

1985
Properties of cytochrome P-450 as affected by environmental factors: qualitative changes due to administration of polycyclic hydrocarbons.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Transport; Environment; Hydrocarbons; Hydrogen-Ion Concentration; Methylcholanthrene; Microsomes, Liver; Morpholines; Phenobarbital; Polycyclic Compounds; Spectrum Analysis; Thyroxine

1971
The histochemical demonstration of aniline hydroxylase activity in rat liver.
    The Histochemical journal, 1971, Volume: 3, Issue:2

    Topics: Acetone; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Diazonium Compounds; Ethanol; Female; Formaldehyde; Histocytochemistry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrogen; Phenobarbital; Phenols; Rats; Staining and Labeling; Time Factors

1971
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
    Molecular pharmacology, 1973, Volume: 9, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats

1973
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1

    Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium

1973
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
    Biochemical and biophysical research communications, 1974, Sep-09, Volume: 60, Issue:1

    Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors

1974
Induction of drug metabolism. IV. Relative abilities of polycyclic hydrocarbons to increase levels of microsomal 3-methyl-4-methylaminoazobenzene N-demethylase activity and cytochrome P1-450.
    Molecular pharmacology, 1970, Volume: 6, Issue:2

    Topics: Aniline Compounds; Animals; Anthracenes; Azo Compounds; Benzopyrenes; Cyanides; Cytochromes; Enzyme Induction; Hydrocarbons; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes; Oxidoreductases; Polycyclic Compounds; Protein Binding; Rats

1970
Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Spectrophotometry

1972
Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system.
    Biochemical and biophysical research communications, 1974, May-20, Volume: 58, Issue:2

    Topics: Animals; Benzopyrenes; Cyanides; Cytochrome c Group; Cytochrome Reductases; Cytochromes; Electron Transport; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NAD; Oxidation-Reduction

1974
Inability of substrates to alter the carbon monoxide and ethyl isocyanide difference spectra of microsomal hemoprotein.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:1

    Topics: Aniline Compounds; Animals; Benzopyrenes; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrophotometry

1971
Properties of benzpyrene hydroxylase in the liver, intestinal mucosa and adrenal of untreated and 3-methylcholanthrene-treated rats.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:3

    Topics: Adrenal Glands; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Intestinal Mucosa; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Rats

1973
Existence and separation of three forms of cytochrome P-450 from rat liver microsomes.
    The Journal of biological chemistry, 1973, Jul-25, Volume: 248, Issue:14

    Topics: Amines; Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Deoxycholic Acid; Enzyme Induction; Ethanol; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Solubility; Spectrophotometry; Subtilisins

1973
Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.
    Molecular pharmacology, 1974, Volume: 10, Issue:2

    Topics: Aminopyrine; Animals; Carbon Monoxide; Carbon Radioisotopes; Chick Embryo; Chlorobenzenes; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dioxins; Dose-Response Relationship, Drug; Enzyme Induction; Methylcholanthrene; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Proteins; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors

1974
Effect of enzyme induction on the metabolism of benzo(a)pyrene and 3'-methyl-4-monomethylaminoazobenzene in the pregnant and fetal rat.
    Cancer research, 1972, Volume: 32, Issue:5

    Topics: Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Carcinogens; Cyanides; Cytochromes; Dealkylation; Enzyme Induction; Female; Fetus; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnancy; Rats; Spectrophotometry; Tritium

1972
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical; Dinitrophenols; Female; Liver; Lung; Male; Methylcholanthrene; Mice; Microsomes; Models, Biological; Nitrites; Proadifen; Pyridoxal Phosphate; Quinones; Rats; Sex Factors; Stimulation, Chemical; Temperature; Time Factors; Urethane; Vanadium; Vitamin K

1968
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates

1969
Ligand interactions with cytochrome P-450. I. Binding of primary amines.
    Biochemistry, 1969, Volume: 8, Issue:8

    Topics: Alcohols; Alkanes; Amines; Animals; Cyanides; Cytochromes; Liver; Male; Methylcholanthrene; Microsomes; Phenobarbital; Rabbits; Spectrophotometry; Stimulation, Chemical

1969
Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats.
    Biochemical and biophysical research communications, 1966, Sep-08, Volume: 24, Issue:5

    Topics: Animals; Cyanides; Cytochromes; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes; Morphine; Phenobarbital; Rats; Spectrophotometry; Transferases

1966
Enhancement by cyanide of aniline p-hydroxylation activity in rat liver microsomes.
    Biochemical pharmacology, 1980, Apr-15, Volume: 29, Issue:8

    Topics: 2,2'-Dipyridyl; Acetone; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cyanides; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Potassium Cyanide; Rats

1980
Renal metabolism of acrylonitrile to cyanide: in vitro studies.
    Pharmacological research, 1999, Volume: 40, Issue:2

    Topics: Acrylonitrile; Animals; Benzimidazoles; Cyanides; Cytochrome P-450 Enzyme System; Ethanol; Fomepizole; Hydrogen-Ion Concentration; Kidney; Male; Methylcholanthrene; Microsomes; NADP; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Sulfhydryl Compounds; Temperature

1999