3-methylcholanthrene has been researched along with cobalt in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (86.49) | 18.7374 |
| 1990's | 3 (8.11) | 18.2507 |
| 2000's | 2 (5.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uehleke, H; Werner, T | 1 |
| Shigematsu, H; Yamano, S; Yoshimura, H | 1 |
| Campbell, RL; Hettrick, JM; Nigro, ND; Suppnick, JD | 1 |
| Anders, MW; Lindstrom, TD | 1 |
| Beatty, PW; Neal, RA; Vaughn, WK | 1 |
| McMurtry, RJ; Mitchell, JR; Snodgrass, WR | 1 |
| Fawade, MM; Pawar, SS | 1 |
| Bell, P; Gutmann, HR | 1 |
| David, JC | 1 |
| Couture, J; Dahlström-King, L; Plaa, GL | 1 |
| Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP | 1 |
| Abraham, NG; Mullane, KM; Pinto, A | 1 |
| Abraham, NG; Carroll, MA; Levere, RD; McGiff, JC; Schwartzman, ML | 1 |
| Ahmed, AE; Ives, K; Jenkins, VK; Perry, RR | 1 |
| Jayarama Bhat, G; Padmanaban, G | 1 |
| Bhat, GJ; Padmanaban, G | 1 |
| Dwarki, VI; Francis, VN; Padmanaban, G | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 2 |
| Bellward, GD; Morgan, RG; Szombathy, VH | 1 |
| Ivashkevich, LG; Shvemberger, IN; Vakhtin, IuB | 1 |
| Finogenova, MA | 1 |
| Sladek, NE | 1 |
| Gautieri, RF; Mann, DE; O'Hara, GP | 1 |
| Gautieri, RF; Mann, DE; Thompson, RS | 1 |
| Narimatsu, S; Watanabe, K; Yamamoto, I; Yoshimura, H | 1 |
| Avren'eva, LI; Kravchenko, LV; Tutel'ian, VA | 1 |
| Babany, G; Cobert, B; Funck-Brentano, C; Larrey, D; Pessayre, D; Tinel, M | 1 |
| Watanabe, K; Yoshizawa, I | 1 |
| Kitagawa, H; Naminohira, S; Saito, H; Sakai, T; Ueno, K | 1 |
| Lindahl, R; Reisdorph, R | 1 |
| Ariyama, J; Furuno, H; Hirai, K; Koyama, J; Shimada, H; Simamura, E | 1 |
| Ali, M; Dayal, M; Dhawan, A; Dwivedi, UN; Parmar, D; Seth, PK | 1 |
| GAUTIERI, RF; MANN, DE; ORZECHOWSKI, RF | 2 |
| GAUTIERI, RF; KASIRSKY, G; MANN, DE | 1 |
37 other study(ies) available for 3-methylcholanthrene and cobalt
| Article | Year |
|---|---|
A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.
Topics: 1-Propanol; Aerobiosis; Age Factors; Anaerobiosis; Animals; Carbon Tetrachloride; Chloroform; Cobalt; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Halothane; Humans; In Vitro Techniques; Lipid Metabolism; Liver; Methylcholanthrene; Mice; Microsomes, Liver; Mitochondria, Liver; NADP; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity | 1975 |
NADH-dependent O-deethylation of p-nitrophenetole with rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Cobalt; Copper; Cytochrome P-450 Enzyme System; Cytochromes; Ethyl Ethers; Hydrogen-Ion Concentration; Iron; Kinetics; Male; Mercury; Methylcholanthrene; Microsomes, Liver; NAD; Oxidoreductases; Oxygen Consumption; Partial Pressure; Phenobarbital; Rabbits | 1976 |
Rat liver microsome-mediated N-demethylation and mutagenicity of azoxymethane.
Topics: Animals; Azo Compounds; Azoxymethane; Benzoflavones; Biotransformation; Chlorides; Cobalt; Diet; Disulfiram; Formaldehyde; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats | 1978 |
Effect of agents known to alter carbon tetrachloride hepatotoxicity and cytochrome P-450 levels on carbon tetrachloride-stimulated lipid peroxidation and ethane expiration in the intact rat.
Topics: 1-Propanol; Animals; Breath Tests; Carbon Tetrachloride; Cobalt; Drug Interactions; Ethane; Ethanol; Lipid Metabolism; Male; Maleates; Methylcholanthrene; Peroxides; Phenobarbital; Rats | 1978 |
Effect of alteration of rat hepatic mixed-function oxidase (MFO) activity on the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Topics: Animals; Castration; Cobalt; Dioxins; Female; Hemin; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Testosterone | 1978 |
Renal necrosis, glutathione depletion, and covalent binding after acetaminophen.
Topics: Acetaminophen; Animals; Chlorides; Cobalt; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Kidney; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Protein Binding; Rats | 1978 |
Alterations in the toxicity of thiodemeton due to the pretreatment of inducers, substrates and inhibitors of mixed function oxidase system.
Topics: Acetanilides; Aminopyrine; Animals; Cobalt; Cycloheximide; Disulfoton; Enzyme Induction; Ethylmorphine; Female; Insecticides; Male; Methylcholanthrene; Mixed Function Oxygenases; Nickel; Oxidoreductases; Phenobarbital; Rats | 1978 |
N-Hydroxylation of arylamides by the rat and guinea pig. Evidence for substrate specificity and participation of cytochrome P1-450.
Topics: 2-Acetylaminofluorene; Animals; Bile; Cobalt; Cytochrome P-450 Enzyme System; Female; Fluorenes; Fluorides; Guinea Pigs; Hydroxyacetylaminofluorene; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Sex Factors; Spectrophotometry; Spectrophotometry, Ultraviolet | 1977 |
Evidence for the possible formation of a toxic tyrosine metabolite by the liver microsomal drug metabolizing system.
Topics: Animals; Benserazide; Biotransformation; Cobalt; Cysteine; Glutathione; Humans; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Proadifen; Tyrosine | 1976 |
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis.
Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Ketones; Liver; Male; Methylcholanthrene; Mirex; Organ Size; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid | 1992 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured | 1990 |
Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Blood Vessels; Cobalt; Cytochrome P-450 Enzyme System; Drug Synergism; Endothelium; Fatty Acids; Indomethacin; Male; Methylcholanthrene; Oxygenases; Phenylephrine; Proadifen; Pulmonary Artery; Pyrazoles; Rabbits; Vasoconstriction; Vasodilation | 1986 |
Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Cobalt; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Kidney; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxygenases; Rabbits | 1986 |
Role of metabolism in effects of diflubenzuron on growth of B16 melanomas in mice.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cobalt; Diflubenzuron; Female; Hydroxylation; Juvenile Hormones; Melanoma; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases | 1986 |
Heme regulates cytochrome P-450 gene transcription elongation.
Topics: Animals; Cell Nucleus; Cobalt; Cytochrome P-450 Enzyme System; Genes; Heme; Kinetics; Methylcholanthrene; Rats; RNA, Messenger; Transcription, Genetic | 1988 |
Heme is a positive regulator of cytochrome P-450 gene transcription.
Topics: Amitrole; Animals; Base Sequence; Cobalt; Cytochrome P-450 Enzyme System; DNA; DNA, Recombinant; Heme; Male; Methylcholanthrene; Molecular Sequence Data; Nucleic Acid Hybridization; Rats; RNA, Messenger; Thioacetamide; Transcription, Genetic | 1988 |
A comparative study of the regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver.
Topics: Amitrole; Animals; Cell Nucleus; Cobalt; Cytochrome P-450 Enzyme System; DNA; Gene Expression Regulation; Glutathione Transferase; Liver; Male; Methylcholanthrene; Phenobarbital; Protein Biosynthesis; Rats; Time Factors; Transcription, Genetic | 1986 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
The effects of pretreatment of mice with norethindrone on the metabolism of 14C-imipramine by the liver microsomal drug-metabolizing enzymes.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cobalt; Cytochrome c Group; Cytochrome Reductases; Dealkylation; Desipramine; Female; Hydrogen-Ion Concentration; Hydroxylation; Imipramine; Methylcholanthrene; Mice; Microsomes, Liver; NADP; Norethindrone; Oxides; Phenobarbital; Proadifen; Time Factors | 1974 |
[Variability of cell elements of myogenic and connective tissue tumors in rats].
Topics: Animals; Carcinogens; Cobalt; Mesenchymoma; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Nickel; Rats; Rhabdomyosarcoma; Sarcoma | 1972 |
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Kidney; Lethal Dose 50; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Piperonyl Butoxide; Rats; Species Specificity; Time Factors; Tritium | 1973 |
[The influence of cobalt on induced cutaneous carcinogenesis].
Topics: Animals; Carcinogens; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Female; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Papilloma; Skin Neoplasms | 1973 |
Therapeutic efficacy of cyclophosphamide as a function of its metabolism.
Topics: Acetamides; Animals; Carcinoma 256, Walker; Cobalt; Cyclophosphamide; Cytochromes; Female; In Vitro Techniques; Kinetics; Leukocyte Count; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Rats; Sodium Chloride; Sulfides | 1972 |
Effect of cobalt chloride and sodium cobaltinitrite on the growth of established epithelial tumors induced by methylcholanthrene.
Topics: Animals; Chlorides; Cobalt; Female; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Nitrites; Skin Neoplasms | 1971 |
Effect of chronic oral administration of sodium cobaltinitrite and sodium nitrite on the minimal carcinogenic dose50 of methylcholanthrene in albino mice.
Topics: Animals; Cobalt; Hypoxia; Methemoglobinemia; Methylcholanthrene; Mice; Nitrites; Sodium | 1965 |
8 alpha, 9 alpha-Epoxyhexahydrocannabinol formation from delta 8-tetrahydrocannabinol by mouse liver microsomes.
Topics: Animals; Cobalt; Dronabinol; Isomerism; Kinetics; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; NAD; NADP; Phenobarbital | 1982 |
[Mechanism of the protective effect of modifiers of the liver enzyme systems metabolyzing xenobiotics in acute T-2 mycotoxicosis].
Topics: Acute Disease; Animals; Cobalt; Drug Evaluation, Preclinical; Enzyme Induction; Inactivation, Metabolic; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Sesquiterpenes; T-2 Toxin | 1984 |
Inactivation of cytochrome P-450 by a troleandomycin metabolite. Protective role of glutathione.
Topics: Animals; Cobalt; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythromycin; Glutathione; Male; Methylcholanthrene; Oleandomycin; Phenobarbital; Rats; Rats, Inbred Strains; Troleandomycin | 1983 |
Induction of liver microsomal 2-hydroxylation of estradiol 17-sulfate by phenobarbital in male rat.
Topics: Animals; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 Enzyme System; Estradiol; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Drug metabolism and fetal toxicity: changes in fetal toxicity of aminopyrine by variation of drug metabolizing enzyme activity in mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cobalt; Female; Fetal Death; Male; Methylcholanthrene; Metyrapone; Mice; Mice, Inbred ICR; Pharmaceutical Preparations; Pregnancy; Proadifen | 1981 |
Hypoxia exerts cell-type-specific effects on expression of the class 3 aldehyde dehydrogenase gene.
Topics: Aldehyde Dehydrogenase; Animals; Cell Hypoxia; Cells, Cultured; Cobalt; Down-Regulation; Epithelium, Corneal; Gene Expression Regulation, Enzymologic; L-Lactate Dehydrogenase; Liver Neoplasms, Experimental; Methylcholanthrene; Rats; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E | 2002 |
Effect of pretreatment of cytochrome P450 (P450) modifiers on neurobehavioral toxicity induced by deltamethrin.
Topics: Animals; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Insecticides; Male; Methylcholanthrene; Motor Activity; Nervous System Diseases; Neurotoxins; Nitriles; Phenobarbital; Pyrethrins; Rats; Rats, Wistar; Tremor | 2003 |
EFFECT OF SODIUM COBALTINITRITE ON THE MINIMAL CARCINOGENIC DOSE-50 (MCD-50) OF METHYLCHOLANTHRENE IN ALBINO MICE.
Topics: Animals; Anions; Carcinogens; Cobalt; Corneal Dystrophies, Hereditary; Methemoglobinemia; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Nitrites; Pharmacology; Research; Sodium; Toxicology | 1964 |
EFFECT OF SODIUM NITRITE AND P-AMINOPROPIOPHENONE ON THE MINIMAL CARCINOGENIC DOSE 50 OF METHYLCHOLANTHRENE ON MOUSE EPIDERMIS.
Topics: Carcinogens; Cobalt; Epidermis; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Nitrites; Pharmacology; Propiophenones; Research; Skin Neoplasms; Sodium Nitrite; Toxicology | 1965 |
EFFECT OF COBALTOUS CHLORIDE ON THE MINIMAL CARCINOGENIC DOSE OF METHYLCHOLANTHRENE IN ALBINO MICE.
Topics: Animals; Carcinogens; Chlorides; Cobalt; Methylcholanthrene; Mice; Neoplasms; Pharmacology; Research | 1965 |