3-methylcholanthrene has been researched along with clofibrate in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Asakura, T; Shichi, H | 1 |
| Burchell, B; Clarke, DJ; George, SG | 1 |
| Miyazaki, S | 1 |
| Appelkvist, EL; Dallner, G; Kalén, A | 1 |
| Heinemeyer, G; Hildebrandt, AG; Nau, H; Roots, I | 1 |
| Russell, DH | 1 |
| Ikeda, T; Kessler, DJ; Nebert, DW; Stupans, I | 1 |
| Hayes, JD; Judah, DJ; McLellan, LI; Neal, GE | 1 |
| Barnett, CR; Clarke, JC; Flatt, PR | 1 |
| Barnett, CR; Clarke, J; Coulter, J; Flatt, PR | 1 |
| Delaforge, M; Le Campion, L; Noel, JP; Ouazzani, J | 1 |
| Alworth, WL; Ertl, RP; Winston, GW | 1 |
| Jemnitz, K; Monostory, K; Vereczkey, L; Veres, Z | 1 |
| Law, MY; Moody, DE; Slawson, MH | 1 |
| Edwards, RJ; Guengerich, FP; Hollenberg, PF; Kim, H; Novak, RF; Putt, DA; Wolf, CR; Zangar, RC | 1 |
| Austin, C; Caskey, CT; Gerhold, D; Lu, M; Rushmore, T; Xu, J | 1 |
| Jemnitz, K; Lengyel, G; Vereczkey, L | 1 |
| Ito, K; Kanbori, M; Kiyosawa, N; Manabe, S; Niino, N; Sakuma, K; Watanabe, T; Yamoto, T | 1 |
20 other study(ies) available for 3-methylcholanthrene and clofibrate
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
12(R)-hydroxyeicosatetraenoic acid synthesis by 3-methylcholanthrene- and clofibrate-inducible cytochrome P450 in porcine ciliary epithelium.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cells, Cultured; Ciliary Body; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Epithelium; Hydroxyeicosatetraenoic Acids; Methylcholanthrene; Microsomes; Stereoisomerism; Swine | 1992 |
Differential expression and induction of UDP-glucuronosyltransferase isoforms in hepatic and extrahepatic tissues of a fish, Pleuronectes platessa: immunochemical and functional characterization.
Topics: Animals; Aroclors; Bilirubin; Blotting, Western; Chlorodiphenyl (54% Chlorine); Clofibrate; Corn Oil; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Flounder; Glucuronosyltransferase; Immunohistochemistry; Intestines; Isoenzymes; Kidney; Liver; Methylcholanthrene; Microsomes; Naphthols; Testosterone; Tissue Distribution | 1992 |
Effect of chemicals on glutathione peroxidase of chick liver.
Topics: Animals; Benzene Derivatives; Butylated Hydroxyanisole; Chickens; Chromatography, Gel; Clofibrate; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Male; Methylcholanthrene; Phenobarbital; Stilbenes | 1991 |
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes.
Topics: Animals; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Dolichols; Endoplasmic Reticulum; Intracellular Membranes; Liver; Methylcholanthrene; Mevalonic Acid; Microbodies; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Ubiquinone | 1990 |
Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Enzyme Induction; Flavonoids; Glucuronates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid | 1985 |
Drug stimulation of putrescine and spermidine syntheses. Relationships to enhancement of ribonucleic acid synthesis.
Topics: Animals; Benzopyrenes; Carboxy-Lyases; Clofibrate; Cycloheximide; Heparin; Liver; Male; Methylcholanthrene; Ornithine; Phenobarbital; Polyamines; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Stimulation, Chemical; Tritium; Uridine | 1971 |
Characterization of a cDNA clone for mouse phenobarbital-inducible cytochrome P-450b.
Topics: Amino Acid Sequence; Animals; Base Sequence; Clofibrate; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Methylcholanthrene; Mice; Phenobarbital; Rabbits; Rats; Species Specificity | 1984 |
Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Clofibrate; Enzyme Induction; Ethoxyquin; Glutathione Transferase; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred F344; Tissue Distribution; Xenobiotics | 1994 |
The role of cytochrome P450 in altered pancreatic B-cell responsiveness.
Topics: Acetone; Animals; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Islets of Langerhans; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Rats; Rats, Wistar | 1997 |
Islet antioxidant and second phase enzyme levels following CYP1A, CYP2E, CYP2B and CYP4A induction.
Topics: Acetone; Animals; Antioxidants; Catalase; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Islets of Langerhans; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar; Superoxide Dismutase | 1997 |
Metabolism of 14C-labelled 5-nitro-1,2,4-triazol-3-one by rat liver microsomes--evidence for the participation of cytochrome P-450.
Topics: Animals; Carbon Radioisotopes; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Fungal Proteins; Glucocorticoids; Male; Methylcholanthrene; Microsomes, Liver; Nitro Compounds; Oxidation-Reduction; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Liver microsomal cytochromes P450-dependent alkoxyphenoxazone O-dealkylation in vitro by alligator and rat: activities, inhibition, substrate preference, and discrimination factors.
Topics: Alligators and Crocodiles; Animals; Chlorodiphenyl (54% Chlorine); Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats; Species Specificity; Substrate Specificity | 1999 |
Glucuronidation of thyroxine in primary monolayer cultures of rat hepatocytes: in vitro induction of UDP-glucuronosyltranferases by methylcholanthrene, clofibrate, and dexamethasone alone and in combination.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Clofibrate; Dexamethasone; Drug Interactions; Enzyme Induction; Glucuronosyltransferase; Hypolipidemic Agents; Liver; Methylcholanthrene; Rats; Thyroxine | 2000 |
Selective involvement of cytochrome P450 2D subfamily in in vivo 4-hydroxylation of amphetamine in rat.
Topics: Amphetamine; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethanol; Hydroxylation; Isoenzymes; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; p-Hydroxyamphetamine; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Safrole | 2000 |
Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Clofibrate; Cycloheximide; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dactinomycin; Deoxyadenosines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Isoenzymes; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Alignment; Transcription, Genetic | 2001 |
Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays.
Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Evaluation, Preclinical; Energy Metabolism; Gene Expression Profiling; Liver; Male; Methylcholanthrene; Oligonucleotide Array Sequence Analysis; Phenobarbital; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Stress, Physiological; Transcriptional Activation; Xenobiotics | 2001 |
In vitro induction of bilirubin conjugation in primary rat hepatocyte culture.
Topics: Animals; Bilirubin; Cells, Cultured; Clofibrate; Dexamethasone; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Glucocorticoids; Glucuronosyltransferase; Hepatocytes; Hypolipidemic Agents; Immunoblotting; Isoenzymes; Male; Methylcholanthrene; Rats; Rats, Wistar; Rifampin | 2002 |
Phylogenetic tree facilitates the understanding of gene expression data on drug metabolizing enzymes obtained by microarray analysis.
Topics: Administration, Oral; Animals; Base Sequence; Butylated Hydroxyanisole; Clofibrate; Cytochrome P-450 Enzyme System; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Phenobarbital; Phylogeny; Rats; Rats, Inbred F344; Xenobiotics | 2003 |