3-methylcholanthrene has been researched along with cimetidine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chieli, E; Romiti, N; Tramonti, G | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Hsieh, CY; Huang, JD | 1 |
| Hermans, JJ; Thijssen, HH | 1 |
| Downing, G; Parkinson, A; Reddy, N; Sonderfan, AJ; Thibeault, DW | 1 |
| Kari, PH; Lu, AY; Vyas, KP; Wang, RW | 1 |
| Imai, Y; Inada, M; Kawata, S; Minami, Y; Noda, S; Tamura, S; Tarui, S | 1 |
| Argenbright, LS; Lu, AY; Miwa, GT; Wang, RW | 1 |
| Duddy, SK; Hsia, MT | 1 |
| Hazama, H; Murase, T; Okuno, H; Sameshima, Y; Shiozaki, Y | 1 |
| Bast, A; Kroes, BH; Savenije-Chapel, EM | 1 |
| Bast, A; Borm, P; Frankhuijzen-Sierevogel, A; Noordhoek, J | 1 |
| Drew, R; Grygiel, JJ; Rowell, J | 1 |
| Combes, RD; Faux, SP | 1 |
| Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH | 1 |
16 other study(ies) available for 3-methylcholanthrene and cimetidine
| Article | Year |
|---|---|
Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Western; Cell Line, Transformed; DNA Primers; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Kidney Tubules, Proximal; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism.
Topics: Acetone; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cimetidine; Dexamethasone; Diazepam; Enzyme Induction; Female; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Safrole; Sex Characteristics; Stereoisomerism; Sulfaphenazole | 1992 |
Comparison of the rat liver microsomal metabolism of the enantiomers of warfarin and 4'-nitrowarfarin (acenocoumarol).
Topics: Acenocoumarol; Animals; Chromatography, High Pressure Liquid; Cimetidine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Stereoisomerism; Warfarin | 1991 |
Oxygen-induced lung damage in newborn rats, potentiated by 3-methylcholanthrene, a P-450 inducer, and lack of protection by cimetidine, a P-450 inhibitor.
Topics: Animals; Animals, Newborn; Cimetidine; Cytochrome P-450 Enzyme System; Drug Synergism; Heart; Lung; Male; Methylcholanthrene; Oxygen; Rats; Rats, Inbred Strains | 1991 |
Biotransformation of lovastatin--III. Effect of cimetidine and famotidine on in vitro metabolism of lovastatin by rat and human liver microsomes.
Topics: Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Female; Humans; Lovastatin; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1990 |
Interaction of famotidine with rat liver microsomes, a study showing less inhibition of drug metabolism than with cimetidine.
Topics: Aminopyrine N-Demethylase; Animals; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Histamine H2 Antagonists; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thiazoles | 1986 |
In vitro studies on the interaction of famotidine with liver microsomal cytochrome P-450.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Histamine H2 Antagonists; Humans; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Spectrum Analysis; Thiadiazoles; Thiazoles | 1988 |
Cytoprotective effects of modulators of oxidative xenobiotic metabolism in precocene II-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzopyrans; Cell Survival; Chemical and Drug Induced Liver Injury; Cimetidine; Dose-Response Relationship, Drug; Insecticides; Male; Methylcholanthrene; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Plants; Proadifen; Rats; Rats, Inbred Strains | 1987 |
Effect of H2-receptor antagonists on acetaminophen-induced hepatic injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Famotidine; Glutathione; Liver; Liver Diseases; Male; Methylcholanthrene; Microsomes, Liver; Ranitidine; Rats; Thiazoles | 1986 |
Inhibition of mono-oxygenase and oxidase activity of rat-hepatic cytochrome P-450 by H2-receptor blockers.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Imidazoles; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Ranitidine; Rats; Rats, Inbred Strains; Safrole | 1984 |
Cytochrome P-450 and ethoxycoumarin-deethylation in rat gastric microsomes: induction by 3-methylcholanthrene and inhibition by cimetidine.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cimetidine; Cytochrome P-450 Enzyme System; Enzyme Induction; Guanidines; Kinetics; Male; Methylcholanthrene; Microsomes; Oxygenases; Rats; Rats, Inbred Strains; Stomach | 1981 |
Cimetidine: a specific inhibitor of hepatic aryl hydrocarbon hydroxylase (AHH) in the rat.
Topics: Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cimetidine; Guanidines; Hexobarbital; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Sleep | 1981 |
Interaction of cimetidine with cytochrome P450 and effect on mixed-function oxidase activities of liver microsomes.
Topics: Animals; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar | 1993 |
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System; Diuretics; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Furosemide; Half-Life; Infusions, Intravenous; Injections, Intravenous; Isoniazid; Male; Methylcholanthrene; Orphenadrine; Proadifen; Quinine; Rats; Rats, Sprague-Dawley; Troleandomycin; Weight Gain | 2009 |