3-methylcholanthrene has been researched along with carbon tetrachloride in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (90.24) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (4.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Uehleke, H; Werner, T | 1 |
| Castro, JA; Diaz Gomez, MI | 1 |
| Seifert, J; Vácha, J | 1 |
| Le Mesurier, SM; Lykke, AW; Stewart, BW | 1 |
| Anders, MW; Lindstrom, TD | 1 |
| Hes, J; Sternson, LA | 1 |
| Drew, RT; Fouts, JR; Lo, RJ; Roth, RP | 1 |
| Carlson, GP; Fuller, GC; Suarez, KA | 1 |
| Docks, EL; Krishna, G | 1 |
| Benbrahim, N; Dubé, C; Ethier, C; Gascon-Barré, M; Tremblay, C; Vallières, S | 1 |
| Berndt, WO; Christenson, WR; Davis, ME | 1 |
| Hughes, H; Mitchell, JR; Smith, CV; Tsokos-Kuhn, JO | 1 |
| Ishidate, K; Nakazawa, Y; Tadokoro, K | 1 |
| Button, J; Clawson, GA; Geller, DA; Hammock, BD; Loury, DN; Moody, DE; Smuckler, EA; Taylor, LA | 1 |
| Degawa, M; Miura, S; Namiki, M; Ohta, A; Ueno, H | 1 |
| Masuda, Y; Yasoshima, M | 1 |
| Degawa, M; Hashimoto, Y; Masuko, T; Namiki, M; Ohta, A | 1 |
| Enosawa, S; Nakazawa, Y | 1 |
| Breimer, DD; de Bree, H; Heij, P; van der Graaff, M; Vermeulen, NP | 1 |
| Nakajima, T; Sato, A | 1 |
| Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G | 1 |
| Burgison, RM; Dietz, AJ | 1 |
| Feuer, G; Granda, V | 1 |
| Reuber, MD | 2 |
| Castro, JA; D'Acosta, N; De Castro, CR; De Ferreyra, EC; Diaz Gomez, MI | 1 |
| Davis, DC; Gillette, JR; Hashimoto, M | 1 |
| Ferreri, AM; Grilli, S; Prodi, G; Rocchi, P | 1 |
| Weisburger, EK; Weisburger, JH | 1 |
| Mirvish, SS; Sidransky, H | 1 |
| Christie, B; Eichelbaum, M; Krishna, G; Reid, WD | 1 |
| Dove, LF; Reuber, MD | 1 |
| Prabhu, VG | 1 |
| Kato, R | 1 |
| Kobayashi, M; Nagashima, H; Nakatsukasa, H; Watanabe, A | 1 |
| Fander, U; Haas, W; Kröner, H | 1 |
| Frank, H; Haussmann, HJ; Remmer, H | 1 |
| Uchida, T | 1 |
2 review(s) available for 3-methylcholanthrene and carbon tetrachloride
| Article | Year |
|---|---|
Microsomes, metabolism and toxicity.
Topics: Animals; Barbiturates; Biotransformation; Carbon Tetrachloride; DDT; Enzyme Induction; Female; Hexobarbital; Male; Methylcholanthrene; Mice; Microsomes, Liver; Pesticides; Phenobarbital; Pituitary Hormones, Anterior; Protein Deficiency; Rabbits; Rats; Steroids; Toxicology | 1969 |
Food additives and chemical carcinogens: on the concept of zero tolerance.
Topics: Animals; Anthracenes; Carbon Tetrachloride; Carcinogens; Fluorine; Food Additives; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; p-Dimethylaminoazobenzene; Rats; Stilbenes | 1968 |
39 other study(ies) available for 3-methylcholanthrene and carbon tetrachloride
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.
Topics: 1-Propanol; Aerobiosis; Age Factors; Anaerobiosis; Animals; Carbon Tetrachloride; Chloroform; Cobalt; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Halothane; Humans; In Vitro Techniques; Lipid Metabolism; Liver; Methylcholanthrene; Mice; Microsomes, Liver; Mitochondria, Liver; NADP; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity | 1975 |
Further studies on the mechanism of the carbon tetrachloride induced polysome breakdown.
Topics: Age Factors; Amitrole; Animals; Carbon Tetrachloride; Cycloheximide; In Vitro Techniques; Liver; Male; Malonates; Methylcholanthrene; Mice; Mice, Inbred A; Niacinamide; Phenobarbital; Polyribosomes; Proadifen; Pyrazoles; Rats | 1976 |
Microsomal inducers of drug-metabolizing enzymes suppress cytidine nucleotide biosynthesis in rat liver.
Topics: Animals; Antimetabolites; Azauridine; Barbiturates; Benzopyrenes; Carbon Tetrachloride; Colchicine; Cycloheximide; Cytarabine; Cytosine Nucleotides; Dactinomycin; DDT; Hydrocortisone; Liver; Male; Methylcholanthrene; Microsomes, Liver; Orotic Acid; Puromycin; Rats; Spermidine | 1975 |
Correlation of biochemical and morphological changes induced by chemical injury to the lung.
Topics: Animals; Carbon Tetrachloride; Carcinogens; DNA; Female; Gasoline; Injections, Intravenous; Methylcholanthrene; Microscopy, Electron; Nitrosomethylurethane; Petroleum; Pulmonary Alveoli; Rats; RNA; Trichloroethylene | 1979 |
Effect of agents known to alter carbon tetrachloride hepatotoxicity and cytochrome P-450 levels on carbon tetrachloride-stimulated lipid peroxidation and ethane expiration in the intact rat.
Topics: 1-Propanol; Animals; Breath Tests; Carbon Tetrachloride; Cobalt; Drug Interactions; Ethane; Ethanol; Lipid Metabolism; Male; Maleates; Methylcholanthrene; Peroxides; Phenobarbital; Rats | 1978 |
Species variations in the metabolism of acetophenone oxime by hepatic enzymes.
Topics: Acetophenones; Amines; Animals; Carbon Tetrachloride; Cricetinae; Cytosol; Depression, Chemical; Hydroxylamines; Liver; Male; Methylcholanthrene; Mice; Microsomes, Liver; Oxidoreductases; Oximes; Phenobarbital; Rabbits; Rats; Species Specificity; Stimulation, Chemical | 1975 |
Dichloromethane inhalation, carboxyhemoglobin concentrations, and drug metabolizing enzymes in rabbits.
Topics: Animals; Carbon Tetrachloride; Carboxyhemoglobin; Hemoglobins; Hydrocarbons, Chlorinated; Male; Methylcholanthrene; Methylene Chloride; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rabbits | 1975 |
Effect of phenobarbital or 3-methylcholanthrene pretreatment on carbon tetrachloride-induced lipid peroxidation in rat liver.
Topics: Animals; Carbon Tetrachloride; In Vitro Techniques; Lipid Metabolism; Liver; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; Peroxides; Phenobarbital; Rats | 1975 |
The role of glutathione in chloroform-induced hepatotoxicity.
Topics: Acetone; Alkanes; Animals; Carbon Tetrachloride; Chloroform; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kidney; Lens, Crystalline; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Propranolol; Rats | 1976 |
In micronodular cirrhosis, hepatocytes retain a normal C-25 hydroxylation capacity toward vitamin D3: a study using the rat carbon tetrachloride-induced cirrhotic model.
Topics: Animals; Calcifediol; Carbon Tetrachloride; Cholecalciferol; Cytochrome P-450 Enzyme System; Hydroxylation; Liver; Liver Cirrhosis, Experimental; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1991 |
Effect in the rat of the interaction of dichloromaleic acid and carbon tetrachloride on renal and hepatic function.
Topics: Animals; Blood Urea Nitrogen; Carbon Tetrachloride; Drinking; Female; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Male; Maleates; Methylcholanthrene; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Water Pollutants; Water Pollutants, Chemical | 1989 |
Alkylating toxins and the liver plasma membrane calcium pump/calcium atpase.
Topics: Acetaminophen; Animals; Bromobenzenes; Calcium; Calcium-Transporting ATPases; Carbon Tetrachloride; Cell Membrane; Homeostasis; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
Evidence for the existence of isozymes of choline kinase and their selective induction in 3-methylcholanthrene- or carbon tetrachloride-treated rat liver.
Topics: Animals; Carbon Tetrachloride; Choline Kinase; Drug Stability; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunodiffusion; Isoelectric Focusing; Isoenzymes; Liver; Male; Methylcholanthrene; Molecular Weight; Phosphotransferases; Rats | 1985 |
Sodium cholate extraction of rat liver nuclear xenobiotic-metabolizing enzymes.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Cholic Acid; Cholic Acids; Cytochrome P-450 Enzyme System; Cytosol; Liver; Male; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Phenobarbital; Propane; Quinone Reductases; Rats; Rats, Inbred Strains | 1988 |
A simple method for assessment of rat cytochrome P-448 isozymes responsible for the mutagenic activation of carcinogenic chemicals.
Topics: Amines; Animals; Biotransformation; Carbon Tetrachloride; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Phenobarbital; Rats | 1988 |
Action of carbon tetrachloride in the reconstituted monooxygenase system using partially purified cytochrome P-450 and P-448.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Lipid Peroxides; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Pentobarbital; Rats; Rats, Inbred Strains | 1987 |
In vivo selection of a low spin form of cytochrome P-448 from 3-methylcholanthrene-induced rat cytochrome P-450 isozymes by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred ACI | 1987 |
Changes in cytochrome P450 molecular species in rat liver in chloroform intoxication.
Topics: Animals; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats.
Topics: Administration, Oral; Aminopyrine; Animals; Aroclors; Carbon Tetrachloride; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hexobarbital; Isoenzymes; Liver; Male; Metabolic Clearance Rate; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Enhanced metabolism of volatile hydrocarbons in rat liver following food deprivation, restricted carbohydrate intake, and administration of ethanol, phenobarbital, polychlorinated biphenyl and 3-methylcholanthrene: a comparative study.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dietary Carbohydrates; Ethanol; Food Deprivation; Hydrocarbons; Liver; Male; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Proteins; Rats; Rats, Inbred Strains; Volatilization | 1985 |
Microsomal phospholipids and drug action--quantitative biochemical and electron microscopic studies.
Topics: Animals; Carbon Tetrachloride; Choline; Coumarins; Dactinomycin; Endoplasmic Reticulum; Ethanol; Ethionine; Female; Glucose-6-Phosphatase; Hexobarbital; Histocytochemistry; In Vitro Techniques; Male; Methylcholanthrene; Microscopy, Electron; Microsomes, Liver; Nitrosamines; Phenobarbital; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats | 1972 |
The biotransformation of 8-ethylthio-6-thiotheophylline sodium in vivo.
Topics: Amines; Animals; Carbon Tetrachloride; Chromatography, Thin Layer; Dactinomycin; Depression, Chemical; Hypnotics and Sedatives; Male; Methylcholanthrene; Oils; Phenobarbital; Proadifen; Rats; Sleep; Stimulation, Chemical; Theophylline; Time Factors | 1968 |
Antagonistic effect of foreign compounds on microsomal enzymes of the liver of the rat.
Topics: Acetates; Amides; Animals; Carbon Tetrachloride; Coumarins; Drug Antagonism; Enzymes; Ethionine; Female; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Phosphoric Monoester Hydrolases; Rats; Toluene | 1970 |
Effect of 3-methylcholanthrene on hyperplastic and early neoplastic hepatic lesions induced in rats by carbon tetrachloride.
Topics: Age Factors; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Genitalia, Male; Hyperplasia; Kidney; Liver Cirrhosis; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; Rats; Sex Factors; Spleen; Thyroiditis | 1970 |
Carbon tetrachloride activation in liver microsomes from rats induced with 3-methylcholantrene.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucose-6-Phosphatase; In Vitro Techniques; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats | 1973 |
Effects of bromobenzene and carbon tetrachloride on the synthesis and release of proteins by perfused rat liver.
Topics: Animals; Benzene Derivatives; Blood Proteins; Bromine; Carbon Isotopes; Carbon Tetrachloride; Erythrocytes; Hydrocarbons, Halogenated; In Vitro Techniques; Leucine; Liver; Male; Methylcholanthrene; Perfusion; Rats | 1973 |
In vivo and in vitro binding of carbon tetrachloride with nucleic acids and proteins in rat and mouse liver.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Carbon Tetrachloride; Cell Nucleus; Cytoplasm; DNA; Ethionine; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Mice; Microsomes, Liver; Nitrosamines; Polynucleotides; Protein Binding; Proteins; Rats; RNA, Ribosomal; Stimulation, Chemical | 1973 |
Labeling in vivo of rat liver proteins by tritium-labeled dimethylnitrosamine. Effect of prior treatment with 3-methylcholanthrene, phenobarbitone, dimethylformamide, diethyl-formamide, aminoacetonitrile, ethionine and carbon tetrachloride.
Topics: Amides; Animals; Carbon Tetrachloride; Carcinogens; Dimethylformamide; Endoplasmic Reticulum; Ethionine; Female; Formamides; Liver; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; Nitriles; Nitrosamines; Phenobarbital; Protein Biosynthesis; Rats; Tritium | 1971 |
3-Methylcholanthrene blocks hepatic necrosis induced by administration of bromobenzene or carbon tetrachloride.
Topics: Animals; Benzene Derivatives; Bromine; Carbon Isotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlorine; Chromatography, Gas; Hydrocarbons, Halogenated; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Naphthalenes; Protein Binding; Rats; Rats, Inbred Strains | 1971 |
Hepatic lesions in aged rats given carbon tetrachloride and 3-methylcholanthrene.
Topics: Age Factors; Animals; Body Weight; Budd-Chiari Syndrome; Carbon Tetrachloride; Drug Synergism; Female; Liver; Liver Cirrhosis; Male; Methylcholanthrene; Rats; Rats, Inbred Strains; Sex Factors | 1971 |
The effect of microsomal enzyme stimulants and depressants on amphetamine aggregation toxicity in mice.
Topics: Amphetamine; Animals; Benzopyrenes; Carbon Tetrachloride; Chlordan; Enzyme Repression; Male; Methylcholanthrene; Mice; Microsomes; Phenobarbital; Proadifen | 1969 |
Contrastic effects of ethionine and carbontetrachloride on ascorbic acid metabolism and on the activity of microsomal drug-metabolizing enzymes in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Carbon Tetrachloride; Chlorobutanol; Ethionine; Female; Injections, Intraperitoneal; Kidney; Liver; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Zoxazolamine | 1967 |
Hepatic vein thrombosis. Increased incidence in rats given methylcholanthrene and carbon tetrachloride.
Topics: Age Factors; Animals; Budd-Chiari Syndrome; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Injections, Subcutaneous; Liver Cirrhosis, Experimental; Male; Methylcholanthrene; Rats; Sex Factors | 1970 |
Potentiation of carbon tetrachloride hepatotoxicity by beta-phenethyl alcohol.
Topics: Acetaminophen; Alanine Transaminase; Alcohols; Animals; Carbon Tetrachloride; Drug Synergism; Ethanol; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenylethyl Alcohol; Rats; Rats, Inbred Strains | 1984 |
The damage of the hepatic mixed functional oxygenase system by CCl4: significance of incorporation of 14CCl4 metabolites in vivo.
Topics: Animals; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholecalciferol; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Cytochromes b5; Female; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Metabolic activation of carbon tetrachloride: induction of cytochrome P-450 with phenobarbital or 3-methylcholanthrene and its effect on covalent binding.
Topics: Anaerobiosis; Animals; Biotransformation; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Immunologically and enzymatically distinct rat choline kinase isozymes.
Topics: Animals; Antibodies; Base Sequence; Carbon Tetrachloride; Cations, Divalent; Choline Kinase; Enzyme Induction; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Proteins; Rats; Rats, Wistar; RNA, Messenger; Substrate Specificity; Tissue Distribution | 1994 |