3-methylcholanthrene has been researched along with beta-naphthoflavone in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 81 (59.56) | 18.7374 |
| 1990's | 27 (19.85) | 18.2507 |
| 2000's | 25 (18.38) | 29.6817 |
| 2010's | 3 (2.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Novikov, KN; Sumbalova, Z; Timofeev, KN | 1 |
| Klahr, S; Reyes, AA | 1 |
| Horie, T; Tanaka, S; Yoshimura, T | 1 |
| Florence, R; McDonnell, WM; Traber, PG; Wang, W | 1 |
| Anderson, LM; Jones, AB; Riggs, CW | 1 |
| McGiff, JC; Oyekan, AO; Quilley, J | 1 |
| Anderson, LM; Chauhan, DP; Miller, MS; Owens, IS | 1 |
| Guyda, HJ | 1 |
| Eriksson, LC; Ritter, E | 1 |
| Khatsenko, OG; Kotelevtsev, SV; Kozlov, IuP; Mitrofanov, DV; Novikov, KN; Ponomarëva, LV; Viner, RI | 1 |
| Bories, P; Daujat, M; Diaz, D; Fabre, I; Maurel, P; Michel, H; Saint Aubert, B | 1 |
| Etoh, H; Misawa, S; Tanaka, E | 1 |
| Forkert, PG; Gelboin, HV; Mirehouse-Brown, P; Park, SS | 1 |
| Anderson, LM; Chauhan, DP; Jones, AB; Miller, MS; Park, SS | 1 |
| Anderson, LM; Jones, AB; Kovatch, RM; Riggs, CW | 1 |
| Anderson, LM; Kovatch, RM; Rice, JM | 1 |
| Brun-Pascaud, M; Gougerot-Pocidalo, MA; Hakim, J; Mansour, H; Marquetty, C; Pocidalo, JJ | 1 |
| Blumer, JL; Frank, DM | 1 |
| Bigelow, SW; Nebert, DW | 1 |
| Appelgren, LE; Brandt, I; Brittebo, EB; Gillner, M; Gustafsson, JA; Söderkvist, P | 1 |
| Abraham, NG; Mullane, KM; Pinto, A | 2 |
| Koliada, AIu | 1 |
| Brun-Pascaud, M; Gougerot-Pocidalo, MA; Mansour, H; Pocidalo, JJ | 1 |
| Abraham, NG; Carroll, MA; Levere, RD; McGiff, JC; Schwartzman, ML | 1 |
| Bansal, SK; Bresnick, E; Caballes, L; Faletto, MB; Gurtoo, HL; Hines, RN; Koser, PL | 1 |
| Ahmed, AE; Ives, K; Jenkins, VK; Perry, RR | 1 |
| Farber, JL; Kyle, ME; Miccadei, S; Nakae, D | 1 |
| Goertz, MP; Jongen, WM; Sandker, GW; Topp, RJ; van Bladeren, PJ | 1 |
| Haasch, ML; Kleinow, KM; Lech, JJ | 1 |
| Azoulay-Dupuis, E; Gougerot-Pocidalo, MA; Levacher, M; Mansour, H; Marquetty, C; Moreau, J | 1 |
| Boyum, KW; Chalberg, SC; Fagan, JB; Merchant, SN; Pasco, DS | 1 |
| Fukushima, M; Katoh, K; Konno, N; Yamauchi, T | 1 |
| Benjamin, T; Grantham, PH; Ramanathan, R; Reddy, TV; Weisburger, EK | 1 |
| Dietz, D; Kornbrust, D | 2 |
| Abbruzzi, R; Bastone, A; Bianchi, M; Bonati, M; Catalani, P; Guaitani, A; Latini, R; Pantarotto, C; Szczawinska, K | 1 |
| Chen, IW; Duggan, DE; Lin, JH; Ulm, EH | 1 |
| Kagawa, N; Mihara, K; Sato, R | 1 |
| Gram, TE; Okine, LK | 1 |
| James, MO; Salhab, AS; Shiverick, KT; Swanson, C | 1 |
| George, JD; Manson, JM | 1 |
| Gad-El Karim, MM; Legator, MS; Sadagopa Ramanujam, VM | 1 |
| Degawa, M; Hashimoto, Y; Kojima, M; Sato, Y | 1 |
| Clarke, L; Frey, AB; Kreibich, G; Wadhera, AB; Waxman, DJ | 1 |
| Chasovnikova, OB; Mishin, VM; Tsyrlov, IB | 1 |
| Kleeberg, U; Klinger, W; Sommer, M | 1 |
| Heinemeyer, G; Hildebrandt, AG; Nau, H; Roots, I | 1 |
| Koivusalo, M; Rautoma, P | 1 |
| Decker, RW; Malejka-Giganti, D; Polovina, MR; Ritter, CL | 1 |
| Kappas, A; Rosenberg, DW; Sardana, MK | 1 |
| Juchau, MR; Namkung, MJ; Nelson, SD; Porubek, DJ | 1 |
| Fischbach, T; Lenk, W | 1 |
| Ahmed, AE; Gad-el-Karim, MM; Legator, MS; Ramanujam, VM | 1 |
| Anderson, LM; Seetharam, S | 1 |
| Ehrich, M; Larsen, C | 1 |
| Lech, JJ; Rau, LA; Vodicnik, MJ | 1 |
| Fujino, T; Gelboin, HV; Guengerich, FP; Park, SS; West, D | 1 |
| Wang, IY | 1 |
| Malejka-Giganti, D; Ritter, CL | 1 |
| Gelboin, HV; Gozukara, EM; Guengerich, FP; Miller, H | 1 |
| Lau, PP; Lu, AY; Pickett, CB; Strobel, HW | 1 |
| Abdel-Tawab, GA; El-Bassiouni, EA; El-Sebae, AH; El-Sewedy, SM; El-Zoghby, SM; Mostafa, MH; Ramadan, M | 1 |
| Decker, RW; Malejka-Giganti, D; Ritter, CL | 1 |
| Gurtoo, HL; Raina, V; Williams, CJ | 1 |
| Shertzer, HG | 1 |
| Masaki, R; Matsuura, S; Tashiro, Y | 1 |
| Bloom, SE; Denison, MS; Hamilton, JW | 1 |
| Ehrich, M; Huckle, WR; Larsen, C | 1 |
| Fagan, J; Gelboin, HV; Gozukara, EM; Guengerich, FP; Pastewka, JV | 1 |
| Crowley, P; Fuhrman-Lane, C; Ortiz, E; Shiverick, KT | 1 |
| Bowman, CM; Manchester, DK; Parker, NB | 1 |
| Kappas, A; Sassa, S; Schneider, J | 1 |
| Arnold, J; Ehrich, M; Larsen, C | 1 |
| Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT | 1 |
| Berrigan, M; Gurtoo, HL; Paigen, B; Raina, V | 1 |
| Guengerich, FP; Martin, MV | 1 |
| Batt, AM; Martin, N; Siest, G | 1 |
| Bryant, BJ; Easterling, R; Nesnow, S; Rudo, K | 1 |
| Steggles, AW; Vlasuk, GP; Walz, FG | 1 |
| Highet, RJ; Jerina, DM; Levin, W; Ryan, DE; Shibata, T; Thomas, PE; Vyas, KP; Yeh, HJ | 1 |
| Nesnow, S | 1 |
| Columelli, S; Cresteil, T; le Provost, E; Leroux, JP | 1 |
| Benjamin, T; Grantham, PH; Reddy, TV; Thorgeirsson, SS; Weisburger, EK | 1 |
| Baron, J; Guengerich, FP; Redick, JA | 1 |
| Kurogochi, Y; Nakashima, T; Nakayama, H | 1 |
| Duvivier, J; Gielen, JE; Van Cantfort, J | 1 |
| Morita, T; Okuda, K; Takada, K; Yoshiga, K | 1 |
| Anderson, LM; Priest, LJ | 1 |
| Alworth, WL; Viswanathan, T | 1 |
| Jonen, HG; Kaufmann, I | 1 |
| Jensen, NM; Nebert, DW; Oka, T; Perry, JW | 1 |
| Fukushima, S; Funae, Y; Imaoka, S; Matsuda, T; Otori, K | 1 |
| Hirvonen, A; Husgafvel-Pursiainen, K; Lindros, KO; Oinonen, T; Saarikoski, S | 1 |
| Adamo, D; Bassi, AM; Castell, JV; Donato, MT; Ferro, M; Gómez-Lechón, MJ; Herrero, E; Penco, S | 1 |
| Buhler, DR; Henderson, MC; Miranda, CL; Reed, RL; Schoor, WP; Zhao, X | 1 |
| Chapman, DE; Juchau, MR; Watters, JJ; Yang, HY | 1 |
| Leff, T; Rosenberg, DW | 1 |
| Ruepp, B; Wermuth, B | 1 |
| Lindros, KO; Oinonen, T; Sippel, H | 1 |
| Forkert, PG; Oladapo, OO | 1 |
| Arai, H; Degawa, M; Hashimoto, Y; Matsuda, K | 1 |
| Demedts, M; Hoet, PH; Nemery, B | 1 |
| Afonso, LO; Campbell, PM; Devlin, RH; Donaldson, EM; Iwama, GK | 1 |
| Husgafvel-Pursiainen, K; Ikonen, TS; Lindros, KO; Oinonen, T; Saarikoski, ST; Ulmanen, I | 1 |
| Fung, J; Iba, MM; Thomas, PE | 1 |
| Matsui, H; Ohhira, S; Watanabe, K | 1 |
| Brauze, D; Malejka-Giganti, D | 1 |
| Chen, TT; Lipsky, MM; Råbergh, CM; Vrolijk, NH | 1 |
| Fleig, WE; Jäger, D; Köhler, C; Kostrubsky, VE; Lehmann, T; May, U; Michalopoulos, GK; Runge, D; Runge, DM; Stolz, DB; Strom, SC | 1 |
| Floreani, M; Napoli, E; Palatini, P | 1 |
| Navas, JM; Segner, H | 1 |
| Isomaa, B; Sandbacka, M | 1 |
| Brown, E; Craft, JA; McPhail, ME; Robertson, FE; Stagg, RM | 1 |
| Auyeung, DJ; Kessler, FK; Ritter, JK | 1 |
| Dayal, M; Dey, A; Dhawan, A; Parmar, D; Seth, PK | 1 |
| Dusatti, F; Ferro, M; Gelardi, A; Morini, F; Penco, S | 1 |
| Di Giulio, RT; Meyer, JN; Nacci, DE | 1 |
| Audus, KL; Avery, ML; Meek, CE | 1 |
| Brown, D; Scott, JG; Wen, Z; Zhang, L | 1 |
| Clark, AF; Fleenor, DL; Hellberg, PE; McCartney, MD; Pang, IH; Stropki, K | 1 |
| Ito, A; Kawanishi, M; Kishi, K; Sakamoto, M; Yagi, T | 1 |
| Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Takeda, M; Yao, J | 1 |
| El-Kadi, AO; Elbekai, RH; Gharavi, N; Korashy, HM; Wills, K | 1 |
| Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Yao, J | 1 |
| Blumberg, WE; Chevion, M; Peisach, J; Stegeman, JJ | 1 |
| Gonzalez, FJ; Iketaki, H; Kimura, S; Kusano, K; Nagata, K; Ueda, R; Yamazoe, Y; Yoshimura, T | 1 |
| Miwa, M; Okino, N; Sato, T; Sugatani, J; Yoshinari, K | 1 |
| Kensler, TW; Kwak, MK | 1 |
| Anderson, GR; Hasan, A; Qadri, I; Quattrochi, LC; Yin, H | 1 |
| Beaton, D; Chen, S; Nguyen, N; Operaña, TN; Tukey, RH | 1 |
| Baer-Dubowska, W; Brauze, D; Cwykiel, J; Szyfter, K; Widerak, M | 1 |
| Akimoto, K; Inui, H; Kodama, S; Ohkawa, H; Okada, K | 1 |
| Inouye, Y; Kanno, Y; Makimura, M; Nakayama, M; Ohara, S; Zhao, S | 1 |
| Brauze, D; Rawłuszko, AA | 1 |
| DeGroot, DE; Denison, MS | 1 |
136 other study(ies) available for 3-methylcholanthrene and beta-naphthoflavone
| Article | Year |
|---|---|
[The effect of lysolecithin on rat liver microsome monooxygenase activity after induction by xenobiotics of the methylcholanthrene type].
Topics: Animals; Anisoles; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Coumarins; Enzyme Induction; Hydroxylation; Intracellular Membranes; Lysophosphatidylcholines; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Polychlorinated Biphenyls; Rats; Substrate Specificity | 1992 |
Cytochrome P-450 pathway in renal function of normal rats and rats with bilateral ureteral obstruction.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blood Pressure; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Glomerular Filtration Rate; Hemodynamics; Ketoconazole; Kidney; Kidney Cortex; Methylcholanthrene; Microsomes; Rats; Rats, Sprague-Dawley; Ureteral Obstruction | 1992 |
Species difference and tissue distribution of uridine diphosphate-glucuronyltransferase activities toward E6080, 1-naphthol and 4-hydroxybiphenyl.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biphenyl Compounds; Dogs; Enzyme Induction; Glucuronosyltransferase; Guinea Pigs; Intestinal Mucosa; Kidney; Lung; Macaca mulatta; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Naphthols; Phenobarbital; Rats; Rats, Sprague-Dawley; Species Specificity; Thiazoles; Tissue Distribution | 1992 |
Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract.
Topics: Animals; Base Sequence; Benzoflavones; beta-Naphthoflavone; Blotting, Northern; Cell Nucleus; Cytochrome P-450 Enzyme System; DNA Probes; Enzyme Induction; Esophagus; Gastric Mucosa; Gene Expression; Gene Expression Regulation, Enzymologic; Intestinal Mucosa; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Mucous Membrane; Oligodeoxyribonucleotides; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Reference Values; RNA, Messenger; Transcription, Genetic | 1992 |
Long-term (imprinting) effects of transplacental treatment of mice with 3-methylcholanthrene or beta-naphthoflavone on hepatic metabolism of 3-methylcholanthrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Female; Gene Expression Regulation; Liver; Longitudinal Studies; Male; Maternal-Fetal Exchange; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenotype; Pregnancy | 1991 |
Cytochrome P-450-dependent vasodilation of rat kidney by arachidonic acid.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; In Vitro Techniques; Indomethacin; Kidney; Male; Methylcholanthrene; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Vasodilation | 1991 |
Gene expression, ontogeny and transplacental induction of hepatic UDP-glucuronosyl transferase activity in mice.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Fetus; Gene Expression; Gestational Age; Glucuronosyltransferase; Liver; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Polychlorinated Dibenzodioxins | 1991 |
Metabolic effects of growth factors and polycyclic aromatic hydrocarbons on cultured human placental cells of early and late gestation.
Topics: Aminoisobutyric Acids; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; ErbB Receptors; Female; Gestational Age; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Methylcholanthrene; Placenta; Polycyclic Compounds; Pregnancy; Thymidine; Time Factors; Tritium | 1991 |
Kinetics of induction of cytosolic benzaldehyde: NADP and propionaldehyde: NAD aldehyde dehydrogenase activities in rat livers from male Wistar rats.
Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Enzyme Induction; Glutathione Transferase; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains | 1991 |
[An immunochemical analysis of the induction of cytochrome P-450 isoforms in the liver of fresh-water fishes by 3-methylcholanthrene, beta-naphthoflavone and aroclor 1254].
Topics: Animals; Antibodies; Antibody Specificity; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Fishes; Flavonoids; Fresh Water; Immunohistochemistry; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Polychlorinated Biphenyls | 1990 |
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.
Topics: Aged; Benzoflavones; beta-Naphthoflavone; Blotting, Northern; Blotting, Western; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life; Humans; In Vitro Techniques; Liver; Male; Methylcholanthrene; Middle Aged; Omeprazole; Oxygenases; Rifampin; RNA, Messenger | 1990 |
The effects of selective cytochrome P-450 inducing agents on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in rats.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Trimethadione | 1990 |
Distribution and induction sites of phenobarbital- and 3-methylcholanthrene-inducible cytochromes P-450 in murine liver: immunohistochemical localization with monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Activation; Epitopes; Immunoenzyme Techniques; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenobarbital | 1988 |
Differential induction of fetal mouse liver and lung cytochromes P-450 by beta-naphthoflavone and 3-methylcholanthrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fetus; Flavonoids; Liver; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Reference Values; RNA | 1989 |
Modification of transplacental tumorigenesis by 3-methylcholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Female; Fetal Diseases; Fetus; Flavonoids; Genotype; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1989 |
Intraperitoneal mesotheliomas induced in mice by a polycyclic aromatic hydrocarbon.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Disease Models, Animal; Drug Interactions; Female; Mesothelioma; Methylcholanthrene; Mice; Mice, Inbred Strains; Peritoneal Neoplasms | 1989 |
Protection of rat from oxygen toxicity by inducers of cytochrome P-450 system.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Lung; Male; Malondialdehyde; Methylcholanthrene; Microsomes; Oxygen; Phenobarbital; Pulmonary Edema; Random Allocation; Rats; Rats, Inbred Strains; Superoxides | 1988 |
Alteration of methylcholanthrene-mediated suppression of cutaneous delayed hypersensitivity by benzoflavone treatment of C57BL/6J mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Drug Hypersensitivity; Enzyme Induction; Female; Flavonoids; Hypersensitivity, Delayed; Immunosuppressive Agents; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Phenobarbital; Polycyclic Compounds; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1988 |
The murine aromatic hydrocarbon responsiveness locus: a comparison of receptor levels and several inducible enzyme activities among recombinant inbred lines.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Polychlorinated Dibenzodioxins; Quinone Reductases; Receptors, Aryl Hydrocarbon; Receptors, Drug; Zoxazolamine | 1986 |
Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytosol; Dioxins; Enzyme Induction; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Olfactory Mucosa; Oxidoreductases; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger; Tissue Distribution | 1987 |
Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Blood Vessels; Cobalt; Cytochrome P-450 Enzyme System; Drug Synergism; Endothelium; Fatty Acids; Indomethacin; Male; Methylcholanthrene; Oxygenases; Phenylephrine; Proadifen; Pulmonary Artery; Pyrazoles; Rabbits; Vasoconstriction; Vasodilation | 1986 |
[Cytochrome P-450 isoforms in the liver of rats treated with phenobarbital, 3-methylcholanthrene and Aroclor 1254 studied by monoclonal antibodies].
Topics: Animals; Antibodies, Monoclonal; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clone Cells; Cytochrome P-450 Enzyme System; Imidazoles; Immunization; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains | 1986 |
[Protection of the pulmonary toxic effects of normobaric oxygen by inducers of cytochrome P450-linked monooxygenases].
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Induction; Methylcholanthrene; Oxygen; Oxygenases; Phenobarbital; Pulmonary Edema; Rats; Rats, Inbred Strains | 1986 |
Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Cobalt; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Kidney; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxygenases; Rabbits | 1986 |
Aflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL/6 mouse liver.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Female; Liver; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nucleic Acid Hybridization; Polychlorinated Biphenyls; RNA, Messenger | 1987 |
Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Coronary Vessels; Cytochrome P-450 Enzyme System; Dinoprost; Dogs; Endothelium; In Vitro Techniques; Indomethacin; Male; Methylcholanthrene; Muscle Contraction; Muscle Relaxation; Proadifen; Prostaglandins F | 1987 |
Role of metabolism in effects of diflubenzuron on growth of B16 melanomas in mice.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cobalt; Diflubenzuron; Female; Hydroxylation; Juvenile Hormones; Melanoma; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases | 1986 |
Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen.
Topics: Acetaminophen; Animals; Benzoflavones; beta-Naphthoflavone; Carmustine; Catalase; Chlorides; Deferoxamine; Drug Resistance; Ferric Compounds; Ferrous Compounds; Free Radicals; Liver; Male; Mannitol; Methylcholanthrene; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1987 |
Modulating effects of beta-naphthoflavone on the induction of SCEs by model compounds with emphasis on benzo[a]pyrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cells, Cultured; Chickens; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Liver; Methylcholanthrene; Microsomes, Liver; Sister Chromatid Exchange | 1988 |
Induction of cytochrome P-450 mRNA in rainbow trout: in vitro translation and immunodetection.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Immunosorbent Techniques; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Reference Values; RNA, Messenger; Salmonidae; Time Factors; Trout | 1988 |
Genetic differences in response to pulmonary cytochrome P-450 inducers and oxygen toxicity.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Oxygen; Phenobarbital; Pulmonary Edema; Species Specificity | 1988 |
Transcriptional and post-transcriptional regulation of the genes encoding cytochromes P-450c and P-450d in vivo and in primary hepatocyte cultures.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Cytochrome P-450 Enzyme System; Genes; Kidney; Kinetics; Liver; Methylcholanthrene; Organ Specificity; Polychlorinated Dibenzodioxins; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic | 1988 |
The effects of drug metabolism inducers on the delayed neurotoxicity and disposition of tri-o-cresyl phosphate in hens following a single intravenous administration.
Topics: Animals; Ataxia; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chickens; Cresols; Dose-Response Relationship, Drug; Female; Flavonoids; Injections, Intravenous; Methylcholanthrene; Nervous System Diseases; Paralysis; Time Factors; Tissue Distribution; Tritolyl Phosphates | 1988 |
Effect of microsomal enzyme inducers on the urinary excretion pattern of mutagenic metabolites of the carcinogen 2,4-toluenediamine.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Carcinogens; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Phenylenediamines; Rats; Rats, Inbred F344 | 1986 |
Effects of pretreatment with inducers of hepatic mixed function oxidases on DNA repair elicited by various compounds in hepatocytes from adult and neonatal rats.
Topics: 2-Acetylaminofluorene; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Carcinogens; DDT; DNA Repair; Enzyme Induction; Female; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Rats | 1987 |
Metabolism of caffeine to 6-amino-5-[N-methylformylamino]-1,3-dimethyluracil in the isolated, perfused liver from control or phenobarbital-, beta-naphthoflavone- and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Drug Interactions; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Uracil | 1987 |
Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bile; Diflunisal; Esters; Ethers; Glucuronates; Hydrogen-Ion Concentration; Male; Metabolic Clearance Rate; Methylcholanthrene; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Salicylates | 1987 |
Structural analysis of cloned cDNAs for polycyclic hydrocarbon-inducible forms of rabbit liver microsomal cytochrome P-450.
Topics: Amino Acid Sequence; Animals; Base Sequence; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Gene Expression Regulation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Molecular Sequence Data; Polycyclic Compounds; Rabbits; RNA, Messenger; Sequence Homology, Nucleic Acid | 1987 |
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions | 1986 |
Differential induction of ethoxyresorufin-O-deethylase in tissues of the rat placenta.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Ear, Inner; Enzyme Induction; Female; Kinetics; Methylcholanthrene; Oxidoreductases; Placenta; Pregnancy; Rats | 1986 |
Strain-dependent differences in the metabolism of 3-methylcholanthrene by maternal, placental, and fetal tissues of C57BL/6J and DBA/2J mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Female; Fetus; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Placenta; Pregnancy; Species Specificity | 1986 |
Correlation between the induction of micronuclei in bone marrow by benzene exposure and the excretion of metabolites in urine of CD-1 mice.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Bone Marrow; Catechols; Cell Nucleus; Chromosome Aberrations; Female; Hydroquinones; Male; Methylcholanthrene; Mice; Mutagenicity Tests; Phenol; Phenols; Proadifen; Toluene | 1986 |
Induction of a high spin form of microsomal cytochrome P-448 in rat liver by 4-aminoazobenzene derivatives.
Topics: Animals; Azo Compounds; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochromes; Dose-Response Relationship, Drug; Male; Methylcholanthrene; Microsomes, Liver; p-Aminoazobenzene; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole | 1986 |
3-(Trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine photolabels a substrate-binding site of rat hepatic cytochrome P-450 form PB-4.
Topics: Animals; Azirines; Benzoflavones; beta-Naphthoflavone; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Iodine Radioisotopes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Photochemistry; Rats | 1986 |
[Comparison of peptide maps and functional properties of monooxygenases induced by 3-methylcholanthrene and beta-naphthoflavone].
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochromes; Enzyme Induction; Flavonoids; Male; Methylcholanthrene; Microsomes, Liver; Peptide Mapping; Rats; Rats, Inbred Strains | 1986 |
Increased response of cytochrome P-450 dependent biotransformation reactions in rat liver to repeated administration of inducers.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Liver; Male; Methylcholanthrene; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Enzyme Induction; Flavonoids; Glucuronates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid | 1985 |
Induction of cytoplasmic aldehyde dehydrogenases in rat tissues by carcinogenic and non-carcinogenic xenobiotics.
Topics: Aldehyde Dehydrogenase; Animals; Benzoflavones; beta-Naphthoflavone; Cytoplasm; Enzyme Induction; Female; Flavonoids; Liver; Methylcholanthrene; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains | 1985 |
Microsomal metabolism of the carcinogen, N-2-fluorenylacetamide, by the mammary gland and liver of female rats. I. Ring- and N-hydroxylations of N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Altered induction response of hepatic cytochrome P-450 to phenobarbital, 3-methylcholanthrene, and beta-naphthoflavone in organotin-treated animals.
Topics: 5-Aminolevulinate Synthetase; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Environmental Exposure; Enzyme Induction; Flavonoids; Liver; Male; Methylcholanthrene; Organotin Compounds; Phenobarbital; Proteins; Rats; Rats, Inbred Strains | 1985 |
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Estradiol; Ethanol; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Placenta; Polychlorinated Dibenzodioxins; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid Hydroxylases | 1985 |
Additional routes in the metabolism of phenacetin.
Topics: Acetylation; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenacetin; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains | 1985 |
Benzene myeloclastogenicity: a function of its metabolism.
Topics: Animals; Benzene; Benzoflavones; beta-Naphthoflavone; Bone Marrow; Catechols; Chromosome Aberrations; Enzyme Induction; Female; Germ-Free Life; Hydroquinones; Male; Methylcholanthrene; Mice; Mixed Function Oxygenases; Phenobarbital; Phenol; Phenols; Sex Factors | 1985 |
Protection against tumorigenesis by 3-methylcholanthrene in mice by beta-naphthoflavone as a function of inducibility of methylcholanthrene metabolism.
Topics: Age Factors; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Enzyme Induction; Flavonoids; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1985 |
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
Drug metabolism in adult white leghorn hens--response to enzyme inducers.
Topics: Aniline Hydroxylase; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chickens; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Flavonoids; Glutathione Transferase; Male; Methylcholanthrene; Mice; Microsomes, Liver; Oxidoreductases, O-Demethylating; Polychlorinated Biphenyls; Rats | 1983 |
The effect of monooxygenase inducing agents on the incorporation of [35S]methionine into hepatic microsomal protein of rainbow trout (Salmo gairdneri).
Topics: Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Methionine; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Rosaniline Dyes; Salmonidae; Time Factors; Trout | 1984 |
Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epitopes; Humans; Hybridomas; Immunization; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Rabbits; Rats | 1982 |
Effects of phenobarbital, 3-methylcholanthrene and beta-naphthoflavone pretreatment on mouse liver microsomal enzymes and on metabolite patterns of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Flavonoids; In Vitro Techniques; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Proteins | 1981 |
Mixed function oxidase in the mammary gland and liver microsomes of lactating rats. Effects of 3-methylcholanthrene and beta-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Female; Flavonoids; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Different patterns of benzo[a]pyrene metabolism of purified cytochromes P-450 from methylcholanthrene, beta-naphthoflavone and phenobarbital treated rats.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Inactivation, Metabolic; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Comparison of cytochromes P-450 with high activity toward benzo[a]pyrene purified from liver microsomes of beta-naphthoflavone and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carbon Monoxide; Carcinogens; Cytochrome P-450 Enzyme System; Dithionite; Flavonoids; Immunodiffusion; Immunoelectrophoresis; Male; Methylcholanthrene; Microsomes, Liver; Rats; Substrate Specificity | 1982 |
Effect of some xenobiotics on kynurenine hydrolase and kynurenine aminotransferase of mouse liver.
Topics: Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Chlorodiphenyl (54% Chlorine); Chlorpromazine; Female; Hydrolases; Liver; Lyases; Methylcholanthrene; Mice; Phenobarbital; Pyrazoles; Transaminases | 1983 |
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats.
Topics: 2-Acetylaminofluorene; Animal Population Groups; Animals; Animals, Suckling; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Female; Flavonoids; Hydroxylation; Lactation; Methylcholanthrene; Microsomes, Liver; Pregnancy; Rats | 1983 |
Genetic expression of aflatoxin metabolism. Effects of 3-methylcholanthrene and beta-naphthoflavone on hepatic microsomal metabolism and mutagenic activation of aflatoxins.
Topics: Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Mutagenicity Tests; Salmonella typhimurium | 1983 |
Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Dimethylnitrosamine; DNA; Indoles; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Phenobarbital; Rats | 1984 |
A biochemical and electron microscopic study of changes in the content of cytochrome P-450 in rat livers after cessation of treatment with phenobarbital, beta-naphtoflavone or 3-methylcholanthrene.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Flavonoids; Immunosorbent Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microscopy, Electron; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cell Differentiation; Chick Embryo; Chickens; Enzyme Induction; Kinetics; Liver; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins | 1983 |
Increase in glucuronide conjugation of aflatoxin P1 after pretreatment with microsomal enzyme inducers.
Topics: Aflatoxins; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Butylated Hydroxytoluene; Chickens; Enzyme Induction; Glucuronates; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Microsomes, Liver; Rats; Rats, Inbred Strains | 1984 |
Induction of cytochrome P-450 mRNAs quantitated by in vitro translation and immunoprecipitation.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Autoradiography; Benzoflavones; beta-Naphthoflavone; Chemical Precipitation; Cytochrome P-450 Enzyme System; Densitometry; Electrophoresis, Polyacrylamide Gel; Female; Immunochemistry; Kinetics; Male; Methylcholanthrene; Phenobarbital; Photofluorography; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Sex Characteristics | 1984 |
Effects of beta-naphthoflavone and 3-methylcholanthrene administered to pregnant rats on steroid metabolism in the isolated basal zone of the placenta.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Fetus; Flavonoids; Maternal-Fetal Exchange; Methylcholanthrene; NADP; Placenta; Pregnancy; Progesterone; Rats | 1984 |
Maternal smoking increases xenobiotic metabolism in placenta but not umbilical vein endothelium.
Topics: Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Enzyme Induction; Female; Humans; Methylcholanthrene; Placenta; Pregnancy; Smoking; Umbilical Veins | 1984 |
Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450.
Topics: Allylisopropylacetamide; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cell Count; Cells, Cultured; Chick Embryo; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Estradiol; Liver; Methylcholanthrene; Phenobarbital | 1983 |
Organophosphate detoxification related to induced hepatic microsomal enzymes of chickens.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Butylated Hydroxytoluene; Chickens; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Dietary Proteins; Enzyme Induction; Female; Inactivation, Metabolic; Liver; Malathion; Methylcholanthrene; Microsomes, Liver | 1984 |
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1980 |
Genetic dependence of hepatic microsome-mediated depression of aflatoxin B1 activation to mutagens in Ames Salmonella typhimurium TA-98 system.
Topics: Aflatoxin B1; Aflatoxins; Animals; beta-Naphthoflavone; Drug Evaluation, Preclinical; Flavonoids; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Microsomes, Liver; Mutation; Salmonella typhimurium; Vitamin K | 1980 |
Purification of cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydratase from a single preparation of rat liver microsomes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats | 1980 |
Induction of group-1 and group-2 UDP-glucuronosyltransferase in microsomes from the livers of C57 Bl/6 mice.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Glucuronosyltransferase; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Safrole; Substrate Specificity | 1981 |
Reanalysis and clarification of the structures of alpha-naphthoflavone dihydrodiols formed by uninduced and induced rat liver microsomes from Charles River CD and Sprague-Dawley rats.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Species differences in cytochromes P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Species Specificity; Stilbenes | 1983 |
Metabolism of alpha-naphthoflavone and beta-naphthoflavone by rat liver microsomes and highly purified reconstituted cytochrome P-450 systems.
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Flavonoids; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry, Ultraviolet | 1983 |
Multiple effects and metabolism of alpha-naphthoflavone in induced and uninduced hepatic microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Flavonoids; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Species Specificity | 1983 |
Immunological and enzymatic comparison of hepatic cytochrome P-450 fractions from phenobarbital-, 3-methylcholanthrene-, beta-naphthoflavone- and 2,3,7,8- tetrachlorodibenzo-p-dioxin-treated rats.
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxins; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Flavonoids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains | 1983 |
Mutagenicity of urine from rats after administration of 2,4-diaminoanisole: the effect of microsomal enzyme inducers.
Topics: Animals; Anisoles; Benzoflavones; beta-Naphthoflavone; Biotransformation; Male; Methylcholanthrene; Mutagenicity Tests; Mutagens; Pentobarbital; Phenylenediamines; Polychlorinated Dibenzodioxins; Rats; Salmonella typhimurium | 1980 |
Effects of 3-methylcholanthrene, beta-naphthoflavone, and phenobarbital on the 3-methylcholanthrene-inducible isozyme of cytochrome P-450 within centrilobular, midzonal, and periportal hepatocytes.
Topics: Animals; Antigen-Antibody Complex; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Immune Sera; Isoenzymes; Male; Methylcholanthrene; Microscopy, Fluorescence; Microsomes, Liver; Organ Specificity; Phenobarbital; Rats | 1982 |
Heterogeneity of hepatic nicotine oxidase.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Isoenzymes; Liver; Male; Methylcholanthrene; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
The influence of five monoxygenase inducers on liver cytosol estradiol receptor levels in the ovariectomized adult rat.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Castration; Cytosol; Enzyme Induction; Female; Liver; Methylcholanthrene; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Receptors, Estradiol; Receptors, Estrogen | 1981 |
Effect of a chemical carcinogen and phorbol esters on sterol metabolism of mouse skin.
Topics: Administration, Topical; Animals; Anthralin; Azacosterol; Benzoflavones; beta-Naphthoflavone; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Phorbol Esters; Phorbols; Skin; Sterols | 1981 |
Reduction in the transplacental carcinogenic effect of methylcholanthrene in mice by prior treatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Female; Fetus; Flavonoids; Liver; Lung Neoplasms; Maternal-Fetal Exchange; Methylcholanthrene; p-Aminohippuric Acid; Pregnancy; Rats | 1980 |
Effects of 1-arylpyrroles and naphthoflavones upon cytochrome P-450 dependent monooxygenase activities.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Female; Flavonoids; In Vitro Techniques; Kinetics; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pyrroles; Rats | 1981 |
Enhanced biotransformation of nitrofurantoin in rats after induction with 3-methylcholanthrene or beta-naphthoflavone.
Topics: Aerobiosis; Animals; beta-Naphthoflavone; Biotransformation; Enzyme Induction; Flavonoids; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Nitrofurantoin; Phenobarbital; Rats | 1980 |
Association between ornithine decarboxylase induction and the Ah locus in mice treated with polycyclic aromatic compounds.
Topics: Alleles; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; beta-Naphthoflavone; Carboxy-Lyases; Dioxins; Enzyme Induction; Flavonoids; Kidney; Liver; Methylcholanthrene; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phenobarbital; Polychlorinated Dibenzodioxins; Protein Kinases; Species Specificity | 1980 |
Induction of CYP isoenzymes in various organs of rats by 3-methylcholanthrene or beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Male; Methylcholanthrene; Rats; Rats, Inbred F344 | 1995 |
Pretranslational induction of cytochrome P4501A enzymes by beta-naphthoflavone and 3-methylcholanthrene occurs in different liver zones.
Topics: Animals; Base Sequence; Benzoflavones; beta-Naphthoflavone; Cell Separation; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Oxidoreductases; Rats; Rats, Wistar; RNA, Messenger | 1994 |
Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Testosterone; Tumor Cells, Cultured; Xenobiotics | 1994 |
Immunological and biochemical characterization of cytochromes P-450 in mullet (Mugil cephalus): comparison with rainbow trout P-450s.
Topics: Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Immunohistochemistry; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oncorhynchus mykiss; Perciformes; Steroid 16-alpha-Hydroxylase; Xenobiotics | 1994 |
Induction in vitro and complete coding region sequence of cytochrome P4501A1 cDNA from cultured whole rat conceptuses during early organogenesis.
Topics: Animals; Base Sequence; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA, Complementary; Embryo, Mammalian; Enzyme Induction; Methylcholanthrene; Molecular Sequence Data; Organ Culture Techniques; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Regulation of cytochrome P450 in cultured human colonic cells.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma, Hepatocellular; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Kinetics; Liver Neoplasms; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Polycyclic aromatic hydrocarbons and phenolic antioxidants do not significantly induce carbonyl reductase in human cell lines.
Topics: Alcohol Oxidoreductases; Antioxidants; Benzoflavones; beta-Naphthoflavone; Butylated Hydroxyanisole; Cell Line; Enzyme Induction; Humans; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); Polycyclic Compounds | 1993 |
Distribution of glutathione S-transferase isoforms in rat liver after induction by beta-naphthoflavone or 3-methylcholanthrene.
Topics: Animals; Benzene Derivatives; beta-Naphthoflavone; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Digitonin; Dinitrochlorobenzene; Enzyme Induction; Enzyme Inhibitors; Glutathione Transferase; Isoenzymes; Liver; Male; Methylcholanthrene; Oxidants; Rats; Rats, Wistar | 1996 |
Detection and localization of CYP1A1/CYP1A2 in murine liver: electrophoresis, immunoblotting and immunocytochemistry.
Topics: Animals; beta-Naphthoflavone; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Electrophoresis; Endoplasmic Reticulum; Enzyme Inhibitors; Immunohistochemistry; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL | 1995 |
Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver.
Topics: Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Carbolines; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Imidazoles; Male; Methylcholanthrene; Microsomes, Liver; Oligonucleotide Probes; p-Aminoazobenzene; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1996 |
In vitro modulation of the P450 activities of hamster and human lung slices.
Topics: Animals; beta-Naphthoflavone; Cell Survival; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Lung; Male; Mesocricetus; Methylcholanthrene | 1997 |
The effect of the aromatase inhibitor fadrozole and two polynuclear aromatic hydrocarbons on sex steroid secretion by ovarian follicles of coho salmon.
Topics: Animals; Aromatase Inhibitors; beta-Naphthoflavone; Enzyme Inhibitors; Estradiol; Fadrozole; Female; Gonadal Steroid Hormones; Methylcholanthrene; Oncorhynchus kisutch; Ovarian Follicle; Polycyclic Aromatic Hydrocarbons | 1997 |
Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and beta-naphthoflavone.
Topics: Animals; beta-Naphthoflavone; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; In Situ Hybridization; Liver; Male; Methylcholanthrene; Multigene Family; Rats; Rats, Wistar; RNA, Messenger | 1998 |
Cytochrome P450 1A1 in rat peripheral blood lymphocytes: inducibility in vivo and bioactivation of benzo[a]pyrene in the Salmonella typhimurium mutagenicity assay in vitro.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Blotting, Western; Bromobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dexamethasone; Enzyme Induction; Lymphocytes; Male; Methylcholanthrene; Mutagenicity Tests; Mutagens; Pyridines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Smoking | 1999 |
Effects of pretreatment with cytochrome P-450 inducers, especially phenobarbital on triphenyltin metabolism and toxicity in hamsters.
Topics: Animals; Aspartate Aminotransferases; beta-Naphthoflavone; Blood Glucose; Carcinogens; Cricetinae; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Organotin Compounds; Phenobarbital; Triglycerides | 1999 |
A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzofurans; beta-Naphthoflavone; Binding, Competitive; Carrier Proteins; Cytochrome P-450 CYP1A1; Cytosol; Female; Glycine N-Methyltransferase; Kinetics; Liver; Methylcholanthrene; Methyltransferases; Molecular Weight; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2000 |
Differential expression of two CYP1A genes in rainbow trout (Oncorhynchys mykiss).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Blotting, Northern; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Induction; Female; Gene Expression Regulation; Liver; Male; Methylcholanthrene; Oncorhynchus mykiss; Polychlorinated Dibenzodioxins; Polymerase Chain Reaction; RNA, Messenger; Safrole; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2000 |
Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes.
Topics: Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; beta-Naphthoflavone; Blotting, Western; Cell Size; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Epidermal Growth Factor; Hepatocyte Growth Factor; Humans; Isoenzymes; Liver; Methylcholanthrene; Mixed Function Oxygenases; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenobarbital; Rifampin; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Vault Ribonucleoprotein Particles | 2000 |
Protective action of cardiac DT-diaphorase against menadione toxicity in guinea pig isolated atria.
Topics: Analysis of Variance; Animals; beta-Naphthoflavone; Dicumarol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Male; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); Protective Agents; Reactive Oxygen Species; Vitamin K | 2000 |
Antiestrogenicity of beta-naphthoflavone and PAHs in cultured rainbow trout hepatocytes: evidence for a role of the arylhydrocarbon receptor.
Topics: Animals; Anthracenes; beta-Naphthoflavone; Carcinogens; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Enzyme-Linked Immunosorbent Assay; Estrogen Antagonists; Female; Hepatocytes; Male; Methoxsalen; Methylcholanthrene; Oncorhynchus mykiss; Polycyclic Aromatic Hydrocarbons; Protein Biosynthesis; Receptors, Aryl Hydrocarbon; Vitellogenins | 2000 |
Glutathione S-transferase and UDP-glucuronyltransferase activity in primary cultures of rainbow trout gill epithelial cells.
Topics: Animals; beta-Naphthoflavone; Cell Separation; Cell Survival; Cells, Cultured; Enzyme Induction; Epithelial Cells; Gills; Glucuronosyltransferase; Glutathione Transferase; Hepatocytes; Methylcholanthrene; Oncorhynchus mykiss; Polycyclic Aromatic Hydrocarbons | 2000 |
Measurement of cytochrome P4501A induction in dab (Limanda limanda) and other teleosts with species-specific cDNA probes: isolation and characterisation of dab cDNA and its use in expression studies with beta-naphthoflavone-treated fish.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Naphthoflavone; Blotting, Northern; Cross Reactions; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Induction; Enzyme Inhibitors; Fishes; Gene Expression; In Situ Hybridization; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Molecular Sequence Data; RNA, Messenger; Sequence Alignment; Sequence Homology, Nucleic Acid; Species Specificity | 2001 |
An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.
Topics: 5' Untranslated Regions; Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Digestive System; DNA, Complementary; Exons; Gene Expression; Glucuronosyltransferase; Humans; Kidney; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Thiones; Thiophenes | 2001 |
Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression.
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Carcinogens; Catalysis; Cytochrome P-450 CYP1A1; Enzyme Induction; Isoenzymes; Lymphocytes; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.
Topics: Benzoflavones; beta-Naphthoflavone; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Inactivation, Metabolic; Keratinocytes; Methylcholanthrene; Metyrapone; Oxidoreductases; Phenobarbital; Xenobiotics | 2001 |
Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments.
Topics: Animals; beta-Naphthoflavone; Creosote; Cytochrome P-450 CYP1A1; Embryo, Nonmammalian; Enzyme Induction; Fresh Water; Fundulidae; Gene Expression Regulation, Enzymologic; Geologic Sediments; Longevity; Methylcholanthrene; Microsomes, Liver; North Carolina; Virginia; Water Pollutants, Chemical | 2002 |
The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.
Topics: Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Methylcholanthrene; Microsomes, Liver; Smoking; Theophylline; Trophoblasts; Tumor Cells, Cultured | 2003 |
Induction of P450 monooxygenases in the German cockroach, Blattella germanica L.
Topics: Acetone; Animals; Benzene Derivatives; beta-Naphthoflavone; Blattellidae; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Ethanol; Isoenzymes; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; RNA, Messenger | 2003 |
Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression.
Topics: Anterior Eye Segment; Antioxidants; Aqueous Humor; beta-Naphthoflavone; Cell Culture Techniques; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glaucoma, Open-Angle; Humans; Hydroquinones; Intraocular Pressure; Matrix Metalloproteinase 3; Methylcholanthrene; Organ Culture Techniques; Trabecular Meshwork; Transcription Factor AP-1; Up-Regulation | 2003 |
Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity.
Topics: Animals; Antibiotics, Antineoplastic; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzopyrenes; beta-Galactosidase; beta-Naphthoflavone; DNA-Binding Proteins; Environmental Pollutants; Genes, Reporter; Growth Inhibitors; Helix-Loop-Helix Motifs; Humans; Indoles; Ligands; Methylcholanthrene; Mice; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Saccharomyces cerevisiae; Transcription Factors | 2003 |
DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Dioxins; Enzyme Induction; Gene Expression Regulation; Liver Neoplasms; Mammary Tumor Virus, Mouse; Methylcholanthrene; Mice; Plasmids; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Response Elements; Sensitivity and Specificity; Transfection; Tumor Cells, Cultured | 2004 |
Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Humans; Hydrogen Peroxide; Ligands; Lipid Peroxidation; Methylcholanthrene; Oxidative Stress; Receptors, Aryl Hydrocarbon; Signal Transduction | 2004 |
Fast-track DRESSA: a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cell Line, Tumor; Dioxins; Hydrocarbons, Halogenated; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Reproducibility of Results; Time Factors | 2005 |
Electron paramagnetic resonance studies on hepatic microsomal cytochrome P-450 from a marine teleost fish.
Topics: Aminobenzoates; Animals; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Induction; Fishes; Methylcholanthrene; Microsomes, Liver | 1977 |
A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.
Topics: 5' Flanking Region; Benz(a)Anthracenes; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; DNA Mutational Analysis; Genetic Vectors; Humans; Methylcholanthrene; Response Elements; RNA, Messenger; Sequence Deletion; Transcriptional Activation | 2006 |
Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants.
Topics: Adipocytes; Aldehyde Dehydrogenase; Animals; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Enzyme Induction; Glutathione Transferase; Intra-Abdominal Fat; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger; Xenobiotics | 2006 |
Induction of 26S proteasome subunit PSMB5 by the bifunctional inducer 3-methylcholanthrene through the Nrf2-ARE, but not the AhR/Arnt-XRE, pathway.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; beta-Naphthoflavone; Cell Line, Tumor; Fibroblasts; Gene Expression Regulation, Enzymologic; Immunoblotting; Luciferases; Methylcholanthrene; Mutation; NF-E2-Related Factor 2; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Binding; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Response Elements; Signal Transduction; Transfection | 2006 |
Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells.
Topics: beta-Naphthoflavone; Cells, Cultured; Cytochrome P-450 CYP1A1; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Hepacivirus; Humans; Ligands; Methylcholanthrene; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Replicon; RNA, Messenger; Transcription, Genetic; Viral Nonstructural Proteins | 2006 |
Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Cytochrome P-450 CYP1A1; Environmental Monitoring; Environmental Pollutants; Enzyme Induction; Glucuronosyltransferase; Green Fluorescent Proteins; Hepatocytes; Humans; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Transcription, Genetic; Transfection | 2007 |
The effect of aryl hydrocarbon receptor ligands on the expression of AhR, AhRR, ARNT, Hif1alpha, CYP1A1 and NQO1 genes in rat liver.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Ligands; Liver; Methylcholanthrene; NAD(P)H Dehydrogenase (Quinone); Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Repressor Proteins; RNA, Messenger | 2006 |
Recombinant aryl hydrocarbon receptors for bioassay of aryl hydrocarbon receptor ligands in transgenic tobacco plants.
Topics: Animals; Bacterial Proteins; beta-Naphthoflavone; Dioxins; Gene Expression; Genes, Reporter; Indigo Carmine; Indoles; Ligands; Methylcholanthrene; Mice; Nicotiana; Plants, Genetically Modified; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Recombinant Proteins; Saccharomyces cerevisiae; Serine Endopeptidases; Transcription Factors | 2009 |
Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells.
Topics: Aldehyde Dehydrogenase 1 Family; beta Catenin; beta-Naphthoflavone; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Methylcholanthrene; Microscopy, Confocal; Neoplastic Stem Cells; Receptors, Aryl Hydrocarbon; Receptors, Notch; Retinal Dehydrogenase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Spheroids, Cellular; Wnt Proteins | 2012 |
The effect of aryl hydrocarbon receptor ligands on the expression of polymerase (DNA directed) kappa (Polκ), polymerase RNA II (DNA directed) polypeptide A (PolR2a), CYP1B1 and CYP1A1 genes in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA-Directed DNA Polymerase; Environmental Pollutants; Female; Ligands; Liver; Methylcholanthrene; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA Polymerase II; RNA, Messenger | 2012 |
Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ligand structure.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; beta-Naphthoflavone; Binding Sites; Cell Line, Tumor; DNA; Genes, Reporter; Guinea Pigs; Immunoprecipitation; Indoles; Kynurenine; Ligands; Methylcholanthrene; Mice; Molecular Structure; Polychlorinated Dibenzodioxins; Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Response Elements; Structure-Activity Relationship; Thiazoles; Transfection | 2014 |