3-methylcholanthrene has been researched along with ascorbic acid in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (62.50) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glenn, HJ; Haynie, P; JPAHNS, MF; Konikowski, T | 1 |
| Grover, PL; Hewer, A; Rattle, H; Sims, P; Tierney, B | 1 |
| Keyler, DE; Mannering, GJ; Renton, KW | 1 |
| Lupulescu, A | 2 |
| Hirohata, T; Kiyohara, C; Omura, M | 1 |
| Ibric, LL; Peterson, AR; Sevanian, A | 1 |
| Kapur, S; Khanduja, KL; Koul, A; Koul, IB; Majid, S; Sharma, RR | 1 |
| Gupta, MP; Khanduja, KL; Koul, A; Koul, IB; Sharma, RR | 1 |
| Abdel-Galil, AM | 1 |
| Welsch, CW | 1 |
| Demopoulos, HB; Seligman, ML | 1 |
| Glenn, HJ; Haynie, TP; Konikowski, T | 1 |
| Kato, R | 1 |
| Degkwitz, E; Leber, HW; Staudinger, H | 2 |
| Ankermann, H; Elger, J; Franke, H; Klinger, W; Reinicke, C; Traeger, A; Volkmann, H; Wahrenberg, I | 1 |
| Dayton, PG; Perel, JM; Snell, MM | 1 |
| Iwamori, S | 1 |
| Horiguchi, Y; Kawabata, T; Nakamura, M | 1 |
| Benedict, WF; Jones, PA; Wheatley, WL | 2 |
| Chen, XT; Wang, XH; Zhang, XY | 1 |
| Belvedere, G; Coon, MJ; Gelboin, HV; Miller, H; Vatsis, KP | 1 |
| de Clerck, Y; Gielen, JE; Gol-Winkler, R | 1 |
| Banic, S | 1 |
| Peterson, AR; Rosin, MP; Stich, HF | 1 |
| Bement, WJ; Gorman, N; Lambrecht, RW; Sinclair, JF; Sinclair, PR; Walton, HS | 1 |
| Hattori, T; Hayashi, Y; Horio, F; Machino, S; Makino, S; Shibata, T; Yoshida, A | 1 |
| Das, P; Rao, AR; Srivastava, PN | 1 |
| Horio, F; Naito, Y; Nishikimi, M; Shibata, T; Yagi, K; Yoshida, A | 1 |
| Horie, T; Horio, F | 1 |
| Babu, JR; Sachdanandam, P; Thangaraju, M; Vasavi, H | 1 |
| Bánhegyi, G; Braun, L; Csala, M; El Koulali, K; Kardon, T; Mandl, J | 1 |
| Kato-Masatsuji, E; Tsuchiya, T; Tsuzuki, T; Umeda, M | 1 |
| HESTER, RW; SILER, RA; TOUSTER, O | 1 |
| MARSH, CA; REID, LM | 1 |
| DAYTON, PG; PEREL, JM; VRINDTEN, P | 1 |
| Citro, G; De Luca, S; Fazi, L; Laviano, A; Mari, A; Molfino, A; Muscaritoli, M; Ramaccini, C; Rossi Fanelli, F | 1 |
1 review(s) available for 3-methylcholanthrene and ascorbic acid
| Article | Year |
|---|---|
Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Animals; Antioxidants; Ascorbic Acid; Castration; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gonadal Steroid Hormones; Insulin; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Methylnitrosourea; Neoplasm Transplantation; Nucleotides, Cyclic; Pituitary Hormones, Anterior; Prostaglandins; Rats; Retinoids; Selenium; Thyroid Hormones; Vitamin E | 1985 |
39 other study(ies) available for 3-methylcholanthrene and ascorbic acid
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Brain tumor-scanning agents compared in an animal model.
Topics: Animals; Ascorbic Acid; Bleomycin; Brain Neoplasms; Chlormerodrin; Gallium; Indium; Iron; Mercury Isotopes; Methylcholanthrene; Mice; Neoplasm Transplantation; Pentetic Acid; Radioisotopes; Radionuclide Imaging; Sarcoma, Experimental; Serum Albumin, Radio-Iodinated; Technetium; Tin; Ytterbium | 1975 |
The formation of dihydrodiols by chemical or enzymic oxidation of 3-methylcholanthrene.
Topics: Animals; Ascorbic Acid; Chemical Phenomena; Chemistry; Edetic Acid; Ferrous Compounds; Hydroxylation; Methylcholanthrene; Mice; Microsomes, Liver; Organ Culture Techniques; Oxidation-Reduction; Rats; Skin | 1978 |
Suppression of the inductive effects of phenobarbital and 3-methylcholanthrene on ascorbic acid synthesis and hepatic cytochrome P-450-linked monooxygenase systems by the interferon inducers, poly rI.rC and tilorone.
Topics: Animals; Ascorbic Acid; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine-N-Demethylase; Fluorenes; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Poly I-C; Rats; Tilorone | 1979 |
Ultrastructure and cell surface studies of cancer cells following vitamin C administration.
Topics: Animals; Ascorbic Acid; Cell Membrane; Incidence; Male; Methylcholanthrene; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1992 |
Vitamin C inhibits DNA, RNA and protein synthesis in epithelial neoplastic cells.
Topics: Animals; Ascorbic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA; Epithelium; Male; Methylcholanthrene; Mice; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; RNA | 1991 |
In vitro effects of L-ascorbic acid (vitamin C) on aryl hydrocarbon hydroxylase activity in hepatic microsomes of mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Enzyme Activation; Humans; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mutagenicity Tests; Mutagens; Polychlorinated Dibenzodioxins; Tumor Cells, Cultured | 1991 |
Mechanisms of ascorbic acid-induced inhibition of chemical transformation in C3H/10T1/2 cells.
Topics: Animals; Ascorbic Acid; Cell Line; Cell Transformation, Neoplastic; Dehydroascorbic Acid; Methylcholanthrene; NAD; Oxidation-Reduction | 1991 |
Inhibition of arylhydrocarbon hydroxylase and cytochrome P-450 by 20-methylcholanthrene and phenobarbital in guinea pig on excessive doses of ascorbic acid.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Cytochrome P-450 Enzyme Inhibitors; Cytochromes b5; Guinea Pigs; Liver; Lung; Male; Methylcholanthrene; Phenobarbital | 1990 |
Effect of excessive intake of ascorbic acid on hepatic and extra-hepatic phase I and phase II drug metabolism in rat.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Colon; Cytochrome P-450 Enzyme System; Glutathione Transferase; Liver; Lung; Male; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
Preventive effect of vitamin C (L-ascorbic acid) on methylcholanthrene-induced soft tissue sarcomas in mice.
Topics: Administration, Oral; Animals; Ascorbic Acid; Female; Methylcholanthrene; Mice; Sarcoma, Experimental; Soft Tissue Neoplasms | 1986 |
Spin-probe analysis of membrane perturbations produced by chemical and physical agents.
Topics: Ascorbic Acid; Benz(a)Anthracenes; Cholesterol; Electron Spin Resonance Spectroscopy; Kinetics; Linoleic Acids; Liposomes; Mathematics; Membranes, Artificial; Methylcholanthrene; Microscopy, Electron; Molecular Conformation; Phosphatidylcholines; Radiation Effects; Spin Labels; Time Factors; Ultraviolet Rays | 1973 |
Renal clearance and brain tumor localization in mice of 99 m Tc compounds of (Sn), DTPA, (iron-ascorbic acid) DTPA, and iron-ascorbic acid.
Topics: Animals; Ascorbic Acid; Brain Chemistry; Brain Neoplasms; Iron; Kidney; Liver; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Pentetic Acid; Radionuclide Imaging; Sarcoma, Experimental; Technetium; Time Factors; Tin | 1972 |
Contrastic effects of ethionine and carbontetrachloride on ascorbic acid metabolism and on the activity of microsomal drug-metabolizing enzymes in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Carbon Tetrachloride; Chlorobutanol; Ethionine; Female; Injections, Intraperitoneal; Kidney; Liver; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Zoxazolamine | 1967 |
[Influence of ascorbic acid on the induction of monooxygenase in liver microsomes].
Topics: Aminopyrine; Animals; Ascorbic Acid; Biotransformation; Cytochromes; Enzyme Induction; Female; Guinea Pigs; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Scurvy; Stimulation, Chemical | 1970 |
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Female; Fetus; Hexobarbital; Liver; Lysosomes; Male; Methylcholanthrene; Microscopy, Electron; Mitochondria, Liver; Phenylbutazone; Pregnancy; Rats | 1970 |
[Studies on the effect of ascorbic acid on the activity and biosynthesis of mixed function oxygenases, as well as the concentration of hemoproteins in the microsome fraction of guinea pig liver].
Topics: Acetanilides; Aminopyrine; Animals; Ascorbic Acid; Cytochromes; Ethionine; Guinea Pigs; Liver; Methylcholanthrene; Microsomes; Oxygenases; Phenobarbital; Scurvy; Stimulation, Chemical | 1969 |
Ascorbic and dehydroascorbic acids in guinea pigs and rats.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Glucose; Guinea Pigs; In Vitro Techniques; Ion Exchange; Liver Glycogen; Male; Methylcholanthrene; Rats; Urine | 1966 |
Local action of stroma-affecting agents in methylcholanthrene carcinogenesis.
Topics: Animals; Ascorbic Acid; Chondroitin; Heparin; Hyaluronoglucosaminidase; Hydrocortisone; Methylcholanthrene; Mice; Sarcoma, Experimental | 1966 |
Effect of ascorbic acid and some reducing agents on N-nitrosopiperidine metabolism by liver microsomes.
Topics: Aldehydes; Animals; Ascorbic Acid; Carcinogens; Guinea Pigs; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Nitroso Compounds; Oxidation-Reduction; Phenobarbital | 1984 |
Inhibition of chemically induced morphological transformation and reversion of the transformed phenotype of ascorbic acid in C3H/10T 1/2 cells.
Topics: Adipose Tissue; Animals; Ascorbic Acid; Cell Division; Cell Transformation, Neoplastic; Collagen; Cyclic AMP; Extracellular Space; Methylcholanthrene; Mice; Phenotype | 1980 |
Ascorbic acid inhibition of 3-methylcholanthrene induced carcinoma of glandular stomach in mice.
Topics: Animals; Ascorbic Acid; Immunity, Cellular; Immunocompetence; Leukocyte Count; Male; Methylcholanthrene; Mice; Stomach Neoplasms; T-Lymphocytes | 1984 |
Differences in anchorage-dependent growth and tumorigenicities between transformed C3H/10T 1/2 cells with morphologies that are or are not reverted to a normal phenotype by ascorbic acid.
Topics: Animals; Ascorbic Acid; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Embryo, Mammalian; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Phenotype | 1982 |
Hydroxylation of benzo[a]pyrene and binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytolu
Topics: Animals; Ascorbic Acid; Benzoflavones; Benzopyrenes; Butylated Hydroxytoluene; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Rabbits | 1980 |
Ascorbic acid effect on methylcholanthrene-induced transformation in C3H10T1/2 clone 8 cells.
Topics: Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Clone Cells; Methylcholanthrene | 1980 |
Vitamin C acts as a cocarcinogen to methylcholanthrene in guinea-pigs.
Topics: Animals; Ascorbic Acid; Guinea Pigs; Methylcholanthrene; Neoplasms, Experimental | 1981 |
The effect of ascorbate on 3-methylcholanthrene-induced cell transformation in C3H/10T1/2 mouse-embryo fibroblast cell cultures.
Topics: Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H | 1980 |
Ascorbic acid inhibits chemically induced uroporphyria in ascorbate-requiring rats.
Topics: Aminolevulinic Acid; Animals; Ascorbic Acid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Diet; Female; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Mutant Strains; Uroporphyrinogens | 1995 |
UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Body Weight; Chloramphenicol; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Injections, Intraperitoneal; Liver; Methylcholanthrene; Molecular Sequence Data; Nitrophenols; Organ Size; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Gunn; Rats, Inbred Strains; RNA, Messenger; Time Factors; Xenobiotics | 1993 |
Influence of ascorbic acid on MCA-induced carcinogenesis in the uterine cervix of mice.
Topics: Animals; Anticarcinogenic Agents; Ascorbic Acid; Female; Methylcholanthrene; Mice; Uterine Cervical Neoplasms | 1993 |
L-gulono-gamma-lactone oxidase is not induced in rats by xenobiotics stimulating L-ascorbic acid biosynthesis.
Topics: Animals; Ascorbic Acid; Blotting, Northern; Cytochrome P-450 Enzyme System; L-Gulonolactone Oxidase; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Sugar Alcohol Dehydrogenases; Tissue Distribution; Xenobiotics | 1993 |
The role of microsomal beta-glucuronidase in ascorbic acid biosynthesis stimulated by xenobiotics in rats.
Topics: Animals; Ascorbic Acid; Blotting, Northern; Glucuronidase; Heterozygote; Homozygote; Hyperbilirubinemia; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Xenobiotics | 1997 |
The salubrious effects of ascorbic acid on cyclophosphamide instigated lipid abnormalities in fibrosarcoma bearing rats.
Topics: Animals; Ascorbic Acid; Cholesterol, LDL; Cholesterol, VLDL; Cyclophosphamide; Fatty Acids, Nonesterified; Fibrosarcoma; Hyperlipidemias; Lipid Metabolism; Male; Methylcholanthrene; Neoplasm Transplantation; Phospholipids; Rats; Rats, Wistar; Sarcoma, Experimental; Triglycerides | 1998 |
Different induction of gulonolactone oxidase in aromatic hydrocarbon-responsive or -unresponsive mouse strains.
Topics: Animals; Ascorbic Acid; Cytochrome P-450 CYP1A1; Glucaric Acid; Glucuronates; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; L-Gulonolactone Oxidase; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Sugar Alcohol Dehydrogenases; Time Factors | 1999 |
Anti-transforming nature of ascorbic acid and its derivatives examined by two-stage cell transformation using BALB/c 3T3 cells.
Topics: 3T3 Cells; Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
The inhibition by ethionine of the enhancement of ascorbic acid excretion by barbital and by 3-methyl cholanthrene in the rat.
Topics: Animals; Ascorbic Acid; Barbital; Barbiturates; Benz(a)Anthracenes; Body Fluids; Ethionine; Methylcholanthrene; Rats; Vitamins | 1960 |
CHANGES IN D-GLUCARIC ACID EXCRETION INDUCED BY STIMULATORS OF ASCORBIC ACID BIOSYNTHESIS.
Topics: Ascorbic Acid; Barbiturates; Benzopyrenes; Carbohydrate Metabolism; Chlorobutanol; Glucaric Acid; Glucuronidase; Lactones; Methylcholanthrene; Oxidoreductases; Pharmacology; Rats; Research; Urine | 1963 |
STUDIES OF THE PROLONGED BIOCHEMICAL EFFECTS OF 3-METHYLCHOLANTHRENE AND OF ITS PHYSIOLOGICAL DISPOSITION IN THE RAT.
Topics: Ascorbic Acid; Barbiturates; Chlorobutanol; Glucuronates; Liver; Metabolism; Methylcholanthrene; Pharmacology; Rats; Research; Urine; Zoxazolamine | 1964 |
Timing of antioxidant supplementation is critical in improving anorexia in an experimental model of cancer.
Topics: Animals; Anorexia; Antioxidants; Ascorbic Acid; Body Weight; Diet; Dietary Supplements; Disease Models, Animal; Drug Administration Schedule; Energy Intake; Hydrogen Peroxide; Interleukin-1beta; Male; Methylcholanthrene; Oxidative Stress; Random Allocation; Rats, Inbred F344; Sarcoma; Vitamin E | 2013 |