3-methylcholanthrene has been researched along with aflatoxin b1 in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (50.00) | 18.7374 |
| 1990's | 15 (41.67) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Lin, DX | 1 |
| Cha, YN; Choi, CY; Park, EH; Park, SH | 1 |
| Ersing, N; Faletto, MB; Gurtoo, HL; Kouli, F; Maccubbin, AE; Vangalio, JA | 1 |
| Fukuhara, M; Inouye, S; Kato, K; Mizokami, K; Niimura, Y; Sakaguchi, M; Takanaka, A | 1 |
| Lamartiniere, CA | 1 |
| Chiang, JY; Lai, TS | 1 |
| Fukuhara, M; Kato, R; Mizokami, K; Nagata, K; Takanaka, A; Yamazoe, Y | 1 |
| Fukuhara, M; Ishidate, M; Mizokami, K; Nohmi, T; Sunouchi, M; Takanaka, A | 1 |
| Al-Sabti, K | 1 |
| Lubet, RA; McCarvill, JT; Putman, DL; Schechtman, LM; Schwartz, JL | 1 |
| Green, JA; Judah, DJ; Neal, GE | 1 |
| Fukuhara, M; Mizokami, K; Nohmi, T; Omori, Y; Takanaka, A | 1 |
| Chen, XR; Sun, L; Yu, YN | 1 |
| Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM | 1 |
| Fukuhara, M; Ohno, Y; Sunouchi, M; Takanaka, A | 1 |
| Bogovskiĭ, SP; Sergeev, BL; Shevchuk, IN; Tanner, RKh; Veĭdebaum, TI | 1 |
| Jones, PA; Wilson, VL | 1 |
| Cortesi, E; Donovan, PJ; Kakunaga, T; Rice, JM; Saffiotti, U | 1 |
| Lambiotte, M; Thierry, N | 1 |
| Metcalfe, SA; Neal, GE | 1 |
| Berrigan, M; Gurtoo, HL; Paigen, B; Raina, V | 1 |
| Colley, PJ; Metcalfe, SA; Neal, GE | 1 |
| Kamataki, T; Kato, R; Uchimaru, R; Ueno, Y; Yoshizawa, H | 1 |
| Abernethy, DJ; Boreiko, CJ; Frazelle, JH; Ragan, DL | 1 |
| Beaune, P; Becquemont, L; Coles, B; Guengerich, FP; Guillouzo, A; Ketterer, B; Langouët, S; Morel, F | 1 |
| Astashkin, EI; Prikhodko, AZ | 1 |
| Bartsch, H; Kirby, GM; Lang, MA; Pelkonen, P; Wild, CP | 1 |
| Hayes, JD; Judah, DJ; McLellan, LI; Neal, GE | 1 |
| Bammler, TK; Buetler, TM; Eaton, DL; Hayes, JD | 1 |
| Coles, B; Guillouzo, A; Ketterer, B; Langouet, S; Maheo, K; Morel, F | 1 |
| DeCicco, LA; Panzeter, PL; Ringer, DP | 1 |
| Astorg, P; Bergès, R; Gradelet, S; Le Bon, AM; Suschetet, M | 2 |
| Chowdhuri, DK; Das, M; Khanna, SK; Paul, BN; Rastogi, S; Shukla, Y | 1 |
| Dalrymple, E; DiProspero, TJ; Lockett, MR | 1 |
36 other study(ies) available for 3-methylcholanthrene and aflatoxin b1
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
[Effects of harman and norharman on aflatoxin B1 and aminopyrine metabolism by phenobarbital and 3-methylcholanthrene-induced rat liver microsomes].
Topics: Aflatoxin B1; Aminopyrine N-Demethylase; Animals; Carbolines; Harmine; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar | 1992 |
Alteration of aflatoxin B1 metabolic profiles and reduction of aflatoxin B1 mutagenicity by hepatic microsomes of rats fed butylated hydroxyanisole.
Topics: Aflatoxin B1; Animals; Butylated Hydroxyanisole; Chromatography, High Pressure Liquid; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1991 |
Altered benzo[a]pyrene metabolism in C3H/10T1/2 cells transformed by aflatoxin B1 or 3-methylcholanthrene.
Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Adducts; gamma-Glutamyltransferase; Glucuronosyltransferase; Glutathione Transferase; Inactivation, Metabolic; Methylcholanthrene | 1990 |
Aflatoxin B1-specific cytochrome P-450 isozyme (P-450-AFB) inducible by 3-methylcholanthrene in golden hamsters.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Blotting, Western; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Enzyme Induction; Guinea Pigs; Isoenzymes; Male; Mesocricetus; Methylcholanthrene; Mice; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Shrews; Species Specificity | 1990 |
Neonatal diethylstilbestrol treatment alters aflatoxin B1-DNA adduct concentrations in adult rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Animals, Newborn; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; Diethylstilbestrol; DNA; Female; Liver; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred Strains; Testis; Time Factors | 1990 |
Aflatoxin B1 metabolism by 3-methylcholanthrene-induced hamster hepatic cytochrome P-450s.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Enzymologic; Liver; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Subcellular Fractions | 1990 |
Complete cDNA sequence of a major 3-methylcholanthrene-inducible cytochrome P-450 isozyme (P-450AFB) of Syrian hamsters with high activity toward aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cricetinae; Cytochrome P-450 Enzyme System; DNA; Genes; Isoenzymes; Male; Mesocricetus; Methylcholanthrene; Molecular Sequence Data; Multigene Family; RNA, Messenger; Sequence Homology, Nucleic Acid; Substrate Specificity | 1989 |
Characterization of three forms of cytochrome P-450 inducible by 3-methylcholanthrene in Golden hamster livers with special reference to aflatoxin B1 activation.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Immunochemistry; In Vitro Techniques; Liver; Male; Mesocricetus; Methylcholanthrene; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Inbred Strains; Shrews; Species Specificity; Substrate Specificity | 1989 |
Carcinogenic-mutagenic chemicals induced chromosomal aberrations in the kidney cells of three cyprinids.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aroclors; Benzidines; Benzo(a)pyrene; Carcinogens; Chlorodiphenyl (54% Chlorine); Chromosome Aberrations; Cyprinidae; Kidney; Methylcholanthrene; Mutagens; Species Specificity | 1985 |
Effects of 3-aminobenzamide on the induction of morphologic transformation by diverse compounds in Balb/3T3 cells in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Ethyl Methanesulfonate; Kinetics; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C | 1986 |
The in vitro metabolism of aflatoxin B1 catalyzed by hepatic microsomes isolated from control or 3-methylcholanthrene-stimulated rats and quail.
Topics: Absorption; Aflatoxin B1; Aflatoxins; Animals; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Rats; Rats, Inbred F344; Species Specificity | 1986 |
Purification and characterization of a form of cytochrome P-450 with high specificity for aflatoxin B1 from 3-methylcholanthrene-treated hamster liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Isoenzymes; Liver; Male; Mesocricetus; Methylcholanthrene; Molecular Weight; Mutagenicity Tests; Phenobarbital; Salmonella typhimurium | 1986 |
A test using cultured cells with induced mixed-function oxygenase in the unscheduled DNA synthesis assay for detecting promutagens/procarcinogens.
Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Cells, Cultured; DNA Damage; DNA Repair; Enzyme Induction; Humans; Methylcholanthrene; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens | 1987 |
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344 | 1987 |
Effects of various inducers on the activities of cytochrome P-450-mixed function oxidases and aflatoxin B1 activation in microsomes of hamster livers.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cricetinae; DNA; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases | 1988 |
[Microsomal and photochemical oxidation of aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Chromatography, High Pressure Liquid; In Vitro Techniques; Kinetics; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Photolysis; Rats; Ultraviolet Rays | 1985 |
Chemical carcinogen-mediated decreases in DNA 5-methylcytosine content of BALB/3T3 cells.
Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Fibroblasts; In Vitro Techniques; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenanthrenes | 1984 |
Dose-response studies on neoplastic transformation of BALB/3T3 clone A31-1-1 cells by aflatoxin B1, benzidine, benzo[a]pyrene, 3-methylcholanthrene, and N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzidines; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C | 1983 |
Glucocorticoid enhancement of aflatoxin B1 cytotoxicity in differentiated rat hepatoma cultures.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Cell Line; Dexamethasone; Hybrid Cells; Liver Neoplasms; Methylcholanthrene; Rats | 1980 |
The metabolism of aflatoxin B1 by hepatocytes isolated from rats following the in vivo administration of some xenobiotics.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carbon Radioisotopes; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred F344 | 1983 |
Genetic dependence of hepatic microsome-mediated depression of aflatoxin B1 activation to mutagens in Ames Salmonella typhimurium TA-98 system.
Topics: Aflatoxin B1; Aflatoxins; Animals; beta-Naphthoflavone; Drug Evaluation, Preclinical; Flavonoids; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Microsomes, Liver; Mutation; Salmonella typhimurium; Vitamin K | 1980 |
A comparison of the effects of pretreatment with phenobarbitone and 3-methylcholanthrene on the metabolism of aflatoxin B1 by rat liver microsomes and isolated hepatocytes in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cytochrome P-450 Enzyme System; DNA; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Inbred F344 | 1981 |
Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Biotransformation; Cell Nucleus; Cytochrome P-450 Enzyme System; DNA; Hydrogen-Ion Concentration; Kinetics; Liver; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats | 1982 |
Initiation of C3H/10T1/2 cell transformation by N-methyl-N'-nitro-N-nitrosoguanidine and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture.
Topics: Aflatoxin B1; Aged; Anticarcinogenic Agents; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Glutathione Transferase; Humans; Infant; Liver; Male; Methylcholanthrene; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Pyrazines; Rifampin; Thiones; Thiophenes; Time Factors | 1995 |
[Effect of aflatoxin B1 on monooxygenase activity in liver microsomes exposed to cytochrome P-450].
Topics: 7-Alkoxycoumarin O-Dealkylase; Aflatoxin B1; Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar | 1994 |
Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.
Topics: Aflatoxin B1; Animals; Blotting, Western; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Pyrazoles; Steroid Hydroxylases | 1994 |
Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Clofibrate; Enzyme Induction; Ethoxyquin; Glutathione Transferase; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred F344; Tissue Distribution; Xenobiotics | 1994 |
Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
Topics: Aflatoxin B1; Aflatoxins; Animals; Anticarcinogenic Agents; Base Sequence; Biotransformation; Carcinogens; Clofibric Acid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Glutathione Transferase; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Pregnenolone Carbonitrile; Pyrazines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Species Specificity; Steroid Hydroxylases; Thiones; Thiophenes | 1996 |
Metabolism of aflatoxin B1 by human hepatocytes in primary culture.
Topics: Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Enzyme Induction; Glutathione; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Pyrazines; Thiones; Thiophenes | 1996 |
Alterations in epidermal growth factor binding to hepatic membranes following dietary exposure of rats to known hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aniline Compounds; Animals; Benzidines; Binding Sites; Carcinogens; Epidermal Growth Factor; Ethionine; Fluorenes; Food Deprivation; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thioacetamide | 1997 |
Modulation of aflatoxin B1 carcinogenicity, genotoxicity and metabolism in rat liver by dietary carotenoids: evidence for a protective effect of CYP1A inducers.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Carotenoids; Diet; DNA Damage; Liver; Male; Methylcholanthrene; Rats; Rats, Wistar; Vitamin A | 1997 |
Dietary carotenoids inhibit aflatoxin B1-induced liver preneoplastic foci and DNA damage in the rat: role of the modulation of aflatoxin B1 metabolism.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Carotenoids; Diet; DNA Damage; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Microsomes, Liver; Precancerous Conditions; Rats; Rats, Wistar; Serum Albumin; Vitamin A | 1998 |
Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Female; gamma-Glutamyltransferase; Glutathione; Glutathione S-Transferase pi; HSP70 Heat-Shock Proteins; Interleukin-1beta; Lipid Peroxidation; Methylcholanthrene; Mice; Ocimum; Ornithine Decarboxylase; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Physiologically relevant oxygen tensions differentially regulate hepatotoxic responses in HepG2 cells.
Topics: Acetaminophen; Aflatoxin B1; Arylsulfotransferase; Cell Culture Techniques; Cell Hypoxia; Cell Survival; Cyclophosphamide; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Hep G2 Cells; Humans; Methylcholanthrene; Oxygen; Polychlorinated Dibenzodioxins | 2021 |