3-methylcholanthrene and 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

3-methylcholanthrene has been researched along with 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199016 (72.73)18.7374
1990's6 (27.27)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dock, L; Jernström, B; Martinez, M2
Gelboin, HV; Park, SS; Pasanen, M; Pelkonen, O; Raunio, H; Sivonen, P; Vähäkangas, K1
Brookes, P; Jennings, BR; Osborne, M; Ridler, PJ1
Gräslund, A; Jernström, B; Waern, F1
Christou, M; Jefcoate, CR; Keller, GM; Pottenger, LH; Wilson, NM1
Dock, L; Eriksson, L; Jernström, B; Martinez, M; Scheu, G; Torndal, UB1
Jefcoate, CR; Keller, GM; Turner, CR1
Jennings, B; Ridler, P1
Chang, RL; Conney, AH; Jerina, DM; Kapur, U; Levin, W; Sayer, JM; Thakker, DR; Wood, AW; Yagi, H1
Jefcoate, CR; Keller, GM1
Bingham, E; Niemeier, RW; Warshawsky, D1
Kato, R; Sugiura, M; Yamazoe, Y1
Fahl, WE; Jefcoate, CR; Shen, AL1
Hamman, JP; Posner, GH; Seliger, HH1
Baan, RA; Roggeband, R; Van den Berg, PT; Van der Wulp, CJ1
Adams, JD; Jerina, DM; Levin, W; Yagi, H1
Bjelogrlic, N; Gelboin, HV; Honkakoski, P; Park, SS; Pelkonen, O; Peng, R; Vähäkangas, K1
Bell, WN; Grisham, JW; Smith, GJ1
Kikkawa, Y; Sindhu, RK1
Burchiel, SW; Lane, J; Lauer, FT; Tannheimer, SL1
Hirakawa, T; Nemoto, N; Takayama, S1

Other Studies

22 other study(ies) available for 3-methylcholanthrene and 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

ArticleYear
The influence of cytochrome P-450 induction on the disposition of carcinogenic benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide in isolated cells.
    Carcinogenesis, 1989, Volume: 10, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Liver; Methylcholanthrene; Rats; Rats, Inbred Strains

1989
Comparison of the formation of benzo[a]pyrene diolepoxide-DNA adducts in vitro by rat and human microsomes: evidence for the involvement of P-450IA1 and P-450IA2.
    Journal of biochemical toxicology, 1989,Summer, Volume: 4, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Enzyme Induction; Female; Humans; In Vitro Techniques; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Species Specificity; Spectrometry, Fluorescence

1989
Electrofluorescence study of polycyclic hydrocarbon diol-epoxide binding to DNA.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1986, May-22, Volume: 227, Issue:1249

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benz(a)Anthracenes; Benzopyrenes; Binding Sites; Carcinogens; DNA; DNA Adducts; Electrochemistry; Epoxy Compounds; Fluorescence; In Vitro Techniques; Methylcholanthrene; Models, Chemical; Polycyclic Compounds; Stereoisomerism

1986
Studies by fluorescence and n.m.r. spectroscopy of the major product formed after further metabolism of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Carcinogenesis, 1986, Volume: 7, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrometry, Fluorescence

1986
Product inhibition of benzo[a]pyrene metabolism in uninduced rat liver microsomes: effect of diol epoxide formation.
    Chemico-biological interactions, 1987, Volume: 61, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains; Uridine Diphosphate Glucuronic Acid

1987
Benzo[a]pyrene metabolism and induction of enzyme-altered foci in regenerating rat liver.
    Chemico-biological interactions, 1988, Volume: 67, Issue:3-4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Glutathione; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Rats; Rats, Inbred Strains; Regeneration

1988
Kinetic determinants of benzo[a]pyrene metabolism to dihydrodiol epoxides by 3-methylcholanthrene-induced rat liver microsomes.
    Molecular pharmacology, 1982, Volume: 22, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Dihydroxydihydrobenzopyrenes; DNA; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Quinones; Rats; Rats, Inbred Strains; Time Factors; Uridine Diphosphate Glucuronic Acid

1982
The binding of polycyclic aromatic hydrocarbon diol-epoxides to DNA.
    Cancer letters, 1984, Volume: 22, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; DNA; Ethidium; Fluorescence Polarization; Isomerism; Methylcholanthrene

1984
Metabolic activation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide to protein-binding products and the inhibitory effect of glutathione and cysteine.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Biotransformation; Carcinogens; Cysteine; Dihydroxydihydrobenzopyrenes; Glutathione; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1984
Effects of a 6-fluoro substituent on the metabolism of benzo(a)pyrene 7,8-dihydrodiol to bay-region diol epoxides by rat liver enzymes.
    The Journal of biological chemistry, 1984, Sep-25, Volume: 259, Issue:18

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Chromatography, High Pressure Liquid; Circular Dichroism; Male; Methylcholanthrene; Microsomes, Liver; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism

1984
Benzo(a)pyrene activation to 7,8-dihydrodiol 9,10-oxide by rat liver microsomes. Control by selective product inhibition.
    The Journal of biological chemistry, 1984, Nov-25, Volume: 259, Issue:22

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Amines; Animals; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 Enzyme System; Kinetics; Male; Mathematics; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains

1984
The effects of a cocarcinogen, ferric oxide, on the metabolism of benzo[a]pyrene in the isolated perfused lung.
    Journal of toxicology and environmental health, 1984, Volume: 14, Issue:2-3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cocarcinogenesis; Ferric Compounds; In Vitro Techniques; Iron; Lung; Male; Methylcholanthrene; Rabbits

1984
Reduction of epoxy derivatives of benzo(a)pyrene by microsomal cytochrome P-450.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Biotransformation; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Oxygen; Rats; Riboflavin

1980
Metabolism of benzo(a)pyrene by isolated hepatocytes and factors affecting covalent binding of benzo(a)pyrene metabolites to DNA in hepatocyte and microsomal systems.
    Archives of biochemistry and biophysics, 1980, Oct-15, Volume: 204, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Cattle; DNA; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Rats

1980
Specificity of chemiluminescence in the metabolism of benzo[a]pyrene to its carcinogenic diol epoxide.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Kinetics; Luminescent Measurements; Methylcholanthrene; Microsomes, Liver; Rats; Structure-Activity Relationship

1981
Detection of DNA adducts in basal and non-basal cells of the hamster trachea exposed to benzo(a)pyrene in organ culture.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1994, Volume: 42, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cricetinae; DNA Adducts; Epithelial Cells; Epithelium; Fluorescent Antibody Technique; Humans; Keratins; Leukocytes; Mesocricetus; Methylcholanthrene; Organ Culture Techniques; Time Factors; Trachea

1994
Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats.
    Chemico-biological interactions, 1995, Mar-30, Volume: 95, Issue:1-2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Binding Sites; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains; Stereoisomerism

1995
Involvement of P450 1A1 in benzo(a)pyrene but not in benzo(a)pyrene-7,8-dihydrodiol activation by 3-methylcholanthrene-induced mouse liver microsomes.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; DNA Repair; In Vitro Techniques; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Spectrometry, Fluorescence

1993
Clonal analysis of the expression of multiple transformation phenotypes and tumorigenicity by morphologically transformed 10T1/2 cells.
    Cancer research, 1993, Feb-01, Volume: 53, Issue:3

    Topics: Animals; Bayes Theorem; Benzopyrenes; Cell Division; Cell Separation; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Mice, Nude; Phenotype

1993
Metabolism of (+)-trans-benzo[a]pyrene-7,8-dihydrodiol by 3-methylcholanthrene-induced rat liver homogenates.
    Toxicology letters, 1995, Volume: 81, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetates; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Glutathione; In Vitro Techniques; Liver; Methylcholanthrene; Oxidoreductases; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Spectrophotometry, Ultraviolet

1995
Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.
    Molecular carcinogenesis, 1999, Volume: 25, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Benzopyrenes; Breast; Calcium; Carcinogens; Cell Line; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA-Binding Proteins; Egtazic Acid; Epithelial Cells; Humans; Methylcholanthrene; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription Factors

1999
Effect of UDP-glucuronic acid on the microsome-mediated binding of benzo(a)pyrene metabolites to calf thymus DNA.
    Carcinogenesis, 1980, Volume: 1, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Dextrans; DNA; Glucuronosyltransferase; Indicators and Reagents; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Wistar; Uridine Diphosphate Glucuronic Acid

1980