3-methylcholanthrene and 2-acetylaminofluorene

3-methylcholanthrene has been researched along with 2-acetylaminofluorene in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	88 (83.81)	18.7374
1990's	13 (12.38)	18.2507
2000's	2 (1.90)	29.6817
2010's	2 (1.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bisgaard, HC; Burt, RK; Gant, TW; Marino, PA; Silverman, JA; Thorgeirsson, SS	1
Chieli, E; Romiti, N; Tramonti, G	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Fiala, AE; Fiala, S; Kettering, WG; Mohindru, A; Morris, HP	1
Hara, E; Kawajiri, K; Masuda, A; Tagashira, Y; Yonekawa, H	1
Boh, E; Burke, VT; Schor, NA	1
Cameron, RG; Farber, E; Joly, JG; Murray, RK; Sharma, RN	1
Cameron, RG; Farber, E; Griffin, MJ; Joly, JG; Murray, RK; Sharma, RN	1
Hirose, M; Ito, N; Miyata, Y; Murasaki, G; Nakanishi, K; Tatematsu, M	1
Khudoley, VV; Pliss, GB	1
Matsushima, T; Sugimura, T	1
Dean, BJ; Hodson-Walker, G; Senner, KR	1
Schut, HA; Thorgeirsson, SS	1
Sivak, A	1
Anichkov, NM	1
DiPaolo, JA; Popescu, NC; Turnbull, D	1
Adamson, RH; Sakai, S; Thorgeirsson, SS	1
Koivula, T; Koivusalo, M; Marselos, M; Törrönen, R	1
Hara, E; Kawajiri, K; Tagashira, Y; Yonekawa, H	2
Allaben, WT; Lazear, EJ; Louie, SC	1
Arnott, MS; Griffin, AC; Jacobs, MM; Marshall, MV	1
Heidelberger, C; Lillehaug, JR; Mondal, S	1
Baldy, WJ; Dwyer, EN; Lotlikar, PD; Nyce, J	1
Martinsen, CS; Zachariah, PK	1
Casciano, DA; Cave, MD; Farr, JA; Oldham, JW	1
Emory, TH; Gutmann, HR; Kaplan, E	1
Parke, DV; Poole, TW	1
Felton, JS; Nebert, DW	1
Lotlikar, PD; Zaleski, K	2
Henry, CJ; Litman, GW; Litman, RT	1
Friedman, MA; Staub, J	1
Bell, P; Gutmann, HR	1
Boobis, AR; Reinhold, C; Thorgeirsson, SS	1
Danz, M; Schmidt, A; Urban, W	1
Nelson, WL; Thorgeirsson, SS	1
McGregor, D	1
Felton, JS; Nebert, DW; Thorgeirsson, SS	1
Becker, FF; Chowdhury, JR; Chowdhury, NR; Lahiri, P; Mackenzie, PI; Novikoff, PM; Saber, MA	1
Degawa, M; Hashimoto, Y; Miura, S	1
Carubelli, R; Friedman, FK; Graham, SA; McCay, PB	1
Eriksson, LC; Ritter, E	1
Bock, KW; Eriksson, LC; Münzel, PA; Röhrdanz, E; Schrenk, D	1
Majeska, JB; Matheson, DW	1
Huang, M; Lindahl, R	1
Harris, C; Juchau, MR; Luchtel, DL; Stark, KL	1
Juchau, MR; Namkung, MJ; Yang, HY	1
Carubelli, R; Friedman, FK; Gelboin, HV; Graham, SA; Miller, H; Park, SS	1
Cameron, RG; Farber, E; Hayes, MA; Roberts, E; Safe, SH	1
Birkett, DJ; Burgess, W; Edwards, AM; Lucas, C; McManus, ME; Stupans, I	1
Cikryt, P; Göttlicher, M	2
Aström, A; DePierre, JW; Månér, S	2
Penn, A; Snyder, C	1
Dietz, D; Kornbrust, D	1
Dallner, G; Edlund, C; Ericsson, J	1
Faustman-Watts, EM; Giachelli, CM; Juchau, MR	1
Bjørnstad, C; Christensen, T; Holme, JA; Søderlund, EJ; Trygg, B	1
Burnet, F; Darby, NJ; Lodola, A	1
Sivak, A; Tu, AS	1
Aström, A; DePierre, JW	1
Decker, RW; Malejka-Giganti, D; Polovina, MR; Ritter, CL	1
Burnet, FR; Darby, NJ; Lodola, A	2
Dent, JG; Graichen, ME	1
Fantel, AG; Faustman-Watts, EM; Giachelli, CM; Greenaway, JC; Juchau, MR; Shepard, TH	1
Bark, DH; Greenaway, JC; Juchau, MR; Shewey, LM	1
Miyauchi, M	1
Ioannides, C; Parke, DV; Parkinson, C	1
Malejka-Giganti, D; Ritter, CL	1
Razzouk, C; Roberfroid, MB	1
Decker, RW; Malejka-Giganti, D; Ritter, CL	1
Ali, B; Kaur, S	1
Erickson, LC; Marsden, E; Smith, CL; Staiano, N; Thorgeirsson, SS	1
Clearfield, MS; Lotlikar, PD; Paik, SM; Pandey, RN	2
Aström, A; Balk, L; DePierre, JW; Meijer, J; Morgenstern, R; Seidegård, J	1
Goldstein, JA; Sundheimer, DW; Weaver, R	1
Lotlikar, PD; Wang, TF	1
Ito, N; Sato, K; Tsuda, H; Yin, Z	1
Flaks, A; Flaks, B	1
McDonald, DS; Oberly, TJ; Piper, CE	1
Gelboin, HV; Park, SS; Sanderson, N; Thorgeirsson, SS	1
Aune, T; Dybing, E; Thorgeirsson, SS	1
Lu, AY; Miwa, GT; West, SB; Wislocki, PG	1
Agazzi-Leonard, E; Batardy-Gregoire, M; Mercier, M; Poncelet, F; Razzouk, C; Roberfroid, M	2
Batardy-Grégoire, M; Razzouk, C; Roberfroid, M	1
Bolck, F; Danz, M	1
Hiraga, K; Kawano, S; Kojima, A	1
Bradshaw, TK; Freedman, RB; Kaderbhai, MA	2
Mercier, M; Razzouk, C; Roberfroid, M	2
Fort, FL; Fujikawa, K; Sakamoto, Y; Samejima, K	1
Holden, HE; Majeska, JB	1
Lenk, W; Rosenbauer-Thilmann, R	1
DeCicco, LA; Panzeter, PL; Ringer, DP	1
Eriksson, LC; Rissler, P; Torndal, UB	1
ISHIDA, H; KAWAI, K; MATSUO, H; MIYAJI, T; MOSZKOWSKI, LI; ODA, T; OGATA, M; SAYAMA, Y; SENOO, T	1
CRAMER, JW; MILLER, EC; MILLER, JA	1
Ahr, HJ; Duan, JD; Enzmann, HH; Jeffrey, AM; Perrone, CE; Schmidt, U; Williams, GM	1
Borlak, J; Corvi, R; Linge, J; Maaser, K; Rohrbeck, A; Salinas, G; Salovaara, S	1

Reviews

3 review(s) available for 3-methylcholanthrene and 2-acetylaminofluorene

Article	Year
Experimental carcinogenesis in small aquarium fishes. Progress in experimental tumor research, 1976, Volume: 20 Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cycasin; Diethylnitrosamine; Dimethylnitrosamine; Female; Fishes; Goldfish; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Sterigmatocystin; Trout	1976
Cocarcinogenesis. Biochimica et biophysica acta, 1979, Feb-04, Volume: 560, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gastrointestinal Neoplasms; Hormones; Humans; Liver Neoplasms; Lung Neoplasms; Membranes; Methylcholanthrene; Models, Biological; Neoplasms; Nutritional Physiological Phenomena; Oncogenic Viruses; Propionibacterium acnes; Protein Biosynthesis; Retroviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Vitamin A	1979
[Experimental replication of bladder tumors. Morphologic features of early stages of their development]. Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:9 Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell Transformation, Neoplastic; DNA, Neoplasm; Epithelium; FANFT; Humans; Hyperplasia; Methylcholanthrene; Methylnitrosourea; Mice; Microscopy, Electron; Naphthalenes; Neoplasms, Experimental; Papilloma; Rats; Schistosoma haematobium; Species Specificity; Sulfonamides; Urinary Bladder Neoplasms	1979

Other Studies

102 other study(ies) available for 3-methylcholanthrene and 2-acetylaminofluorene

Article	Year
Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene--mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver. Molecular carcinogenesis, 1991, Volume: 4, Issue:6 Topics: 2-Acetylaminofluorene; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Resistance; Enzyme Induction; Gene Expression Regulation; In Vitro Techniques; Liver; Male; Membrane Glycoproteins; Methylcholanthrene; Multigene Family; Oxidoreductases; Rats; Rats, Inbred F344; RNA, Messenger; Time Factors; Transcription, Genetic	1991
Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. Toxicology and applied pharmacology, 2002, Sep-01, Volume: 183, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Western; Cell Line, Transformed; DNA Primers; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Kidney Tubules, Proximal; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2002
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Glutathione and gamma glutamyl transpeptidase in rat liver during chemical carcinogenesis. Journal of the National Cancer Institute, 1976, Volume: 57, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Chloramphenicol; gamma-Glutamyltransferase; Glutathione; Liver Neoplasms; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Puromycin; Rats	1976
In vitro binding of 2-acetaminofluorene to RNA and protein with rat liver microsomes. Gan, 1978, Volume: 69, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Cytosol; Fluorenes; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Protein Binding; Proteins; Rats; RNA	1978
Carcinogens and dicumarol: opposite effects on rat liver NAD(P)H dehydrogenation. Enzyme, 1978, Volume: 23, Issue:4 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Carcinogens; Dicumarol; Male; Methylcholanthrene; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Quinone Reductases; Rats	1978
Multiple patterns of induction of rat liver microsomal mono-oxygenases and other polypeptides by xenobiotics [proceedings]. Biochemical Society transactions, 1979, Volume: 7, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Ethanol; Female; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone; Rats; Safrole	1979
Multiplicity of induction patterns of rat liver microsomal mono-oxygenases and other polypeptides produced by administration of various xenobiotics. The Biochemical journal, 1979, Aug-15, Volume: 182, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethanol; Female; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Peptide Biosynthesis; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Safrole	1979
Enhancing effect of inducers of liver microsomal enzymes on induction of hyperplastic liver nodules by N-2-fluorenylacetamide in rats. Journal of the National Cancer Institute, 1979, Volume: 63, Issue:6 Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Enzyme Induction; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Precancerous Conditions; Rats; Rats, Inbred F344	1979
Tumor induction by carcinogenic agents in aquarium fish. Journal of the National Cancer Institute, 1975, Volume: 55, Issue:1 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct; Animals; Azo Compounds; Benzidines; Carcinogens; Carcinoma, Hepatocellular; Female; Fishes; Intestinal Neoplasms; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; Nitrosamines	1975
Organotropic mutagenesis in tissues of Chinese hamsters induced by chemical carcinogens. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1979, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cells, Cultured; Cricetinae; Cricetulus; Diet; Mesylates; Methylcholanthrene; Mice; Mutagens	1979
In vitro metabolism and mutagenic activation of 2-acetylaminofluorene by subcellular liver fractions from Cotton rats. Cancer research, 1978, Volume: 38, Issue:8 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Flavonoids; Fluorenes; Hydroxyacetylaminofluorene; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Naphthalenes; Paraoxon; Rats; Salmonella typhimurium; Species Specificity	1978
Sister chromatid exchange and chromosome aberration analysis with the use of several carcinogens and noncarcinogens. Journal of the National Cancer Institute, 1977, Volume: 59, Issue:1 Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acridines; Benzopyrenes; Carcinogens; Cell Line; Chromosome Aberrations; Chromosomes; Drug Evaluation, Preclinical; Hydroxyurea; Methylcholanthrene; Methylnitronitrosoguanidine; Phenanthrenes; Polycyclic Compounds; Pyrenes	1977
Induction of monooxygenases in rhesus monkeys by 3-methylcholanthrene: metabolism and mutagenic activation of N-2-acetylaminofluorene and benzo(a)pyrene. Journal of the National Cancer Institute, 1978, Volume: 60, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Fluorenes; Haplorhini; Liver Neoplasms; Lung; Macaca mulatta; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mutagens; Neoplasms, Experimental; Salmonella typhimurium	1978
Comparison of phenobarbital- and carcinogen-induced aldehyde dehydrogenases in the rat. Biochimica et biophysica acta, 1979, Feb-19, Volume: 583, Issue:1 Topics: 2-Acetylaminofluorene; Aldehyde Oxidoreductases; Animals; Benzopyrenes; Carcinogens; Chrysenes; Cytoplasm; Enzyme Induction; Female; Intestinal Mucosa; Liver; Methylcholanthrene; Mitochondria; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Urethane	1979
Activation of 2-acetylaminofluorene in the nuclei of rat liver. Cancer research, 1979, Volume: 39, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cell Nucleus; DNA; Fluorenes; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats	1979
Synergistic effect of diethylstilbestrol on the mutagenicity of 2-acetylaminofluorene and N-hydroxy-acetylaminofluorene in the Salmonella assay system. Cancer letters, 1979, Volume: 7, Issue:2-3 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Diethylstilbestrol; Drug Evaluation, Preclinical; Drug Synergism; Female; Hydroxyacetylaminofluorene; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mice; Mutagens; Rats	1979
Selenium effects on the carcinogenicity and metabolism of 2-acetylaminofluorene. Cancer letters, 1979, Volume: 7, Issue:6 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Hydroxyacetylaminofluorene; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Microsomes, Liver; Rats; Selenium	1979
Establishment of epithelial cell lines from adult mouse regenerating liver. In vitro, 1979, Volume: 15, Issue:11 Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Cell Division; Cell Line; Chromosomes; Clone Cells; Dimethylnitrosamine; Diploidy; Epithelium; Liver; Liver Regeneration; Methylcholanthrene; Mice	1979
Phospholipid requirement for 2-acetamidofluorene N-and ring-hydroxylation by hamster liver microsomal cytochrome P-450 enzyme system. The Biochemical journal, 1977, Dec-15, Volume: 168, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Fluorenes; Hydroxylation; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Phospholipids	1977
Growth of various bacteria on polycyclic aromatic hydrocarbons and N-2-fluorenylacetamide. The Journal of applied bacteriology, 1978, Volume: 44, Issue:3 Topics: 2-Acetylaminofluorene; Bacteria; Benzopyrenes; Chromatography, High Pressure Liquid; Culture Media; Enterobacteriaceae; Fluorenes; Hydroxylation; Methylcholanthrene; Polycyclic Compounds	1978
2-acetylaminofluorene-induced unscheduled DNA synthesis in hepatocytes isolated from 3-methylcholanthrene treated rats. Cancer letters, 1978, Volume: 5, Issue:3 Topics: 2-Acetylaminofluorene; Animals; DNA; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Fluorenes; Hydroxyacetylaminofluorene; In Vitro Techniques; Liver; Methylcholanthrene; Rats	1978
Microsomal metabolism of arylamides by the rat and guinea pig--I. Oxidation of N-3-fluorenylacetamide at carbon-atom-9--a major metabolic reaction. Biochemical pharmacology, 1978, Volume: 27, Issue:11 Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme System; Fluorenes; Guinea Pigs; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats	1978
Biochemical basis for the resistance of guinea pigs to carcinogenesis by 2-acetylaminofluorene. Biochemical and biophysical research communications, 1978, Dec-14, Volume: 85, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Cell Nucleus; Cytochromes; DNA; Drug Resistance; Fluorenes; Guinea Pigs; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Spectrophotometry	1978
Effects of age, inducing agents and carcinogens on the distribution of cytochrome P-450 in microsomal membranes from rat liver. Biochemical Society transactions, 1978, Volume: 6, Issue:5 Topics: 2-Acetylaminofluorene; Aging; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrum Analysis	1978
Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450. The Journal of biological chemistry, 1975, Sep-10, Volume: 250, Issue:17 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Crosses, Genetic; Cytochrome P-450 Enzyme System; Female; Genes; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Mutagens; Oxygenases; Phenobarbital; Species Specificity	1975
Ring-andN-hydroxylation of 2-acetamidofluorene by rat liver reconstituted cytochrome P-450 enzyme system. The Biochemical journal, 1975, Volume: 150, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme System; Female; Fluorenes; Hydroxylation; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Rats; Ribosomal Proteins	1975
Analysis of lipophilic carcinogen-membrane interactions using a model human erythrocyte membrane system. Cancer research, 1976, Volume: 36, Issue:2 Pt 1 Topics: 2-Acetylaminofluorene; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Membrane; Cell Membrane Permeability; Drug Interactions; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Lysogeny; Methylcholanthrene; Models, Biological; p-Dimethylaminoazobenzene	1976
Induction of micronuclei in mouse and hamster bone-marrow by chemical carcinogens. Mutation research, 1977, Volume: 43, Issue:2 Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cricetinae; Dimethylnitrosamine; Erythrocytes; Female; Fluorenes; Injections, Intraperitoneal; Male; Methylcholanthrene; Mice; Nitrosamines	1977
N-Hydroxylation of arylamides by the rat and guinea pig. Evidence for substrate specificity and participation of cytochrome P1-450. Biochimica et biophysica acta, 1977, Jun-23, Volume: 498, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Bile; Cobalt; Cytochrome P-450 Enzyme System; Female; Fluorenes; Fluorides; Guinea Pigs; Hydroxyacetylaminofluorene; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Sex Factors; Spectrophotometry; Spectrophotometry, Ultraviolet	1977
Induction of aryl hydrocarbon (benzo[a]pyrene) hydroxylase and 2-acetylaminofluorene N-hydroxylase by polycyclic hydrocarbons in regenerating liver from inbred strains of mice. Biochemical pharmacology, 1977, Aug-15, Volume: 26, Issue:16 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Enzyme Induction; Female; Hepatectomy; Liver Regeneration; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Time Factors	1977
Prevention of 2-acetylaminofluorene-induced extrahepatic short-term effects by 3-methylcholanthrene. Experimentelle Pathologie, 1977, Volume: 13, Issue:4-5 Topics: 2-Acetylaminofluorene; Adrenal Glands; Animals; Carcinogens; Fluorenes; Liver; Male; Methylcholanthrene; Mitosis; Organ Size; Rats; Spleen	1977
Separation and quantitative determination of 2-acetyl-aminofluorene and its hydroxylated metabolites by high pressure liquid chromatography. Analytical biochemistry, 1976, Volume: 75, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Chromatography, High Pressure Liquid; Fluorenes; Hydroxylation; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Structure-Activity Relationship	1976
The relationship of 2-acetamidofluorene mutagenicity in plate tests with its in vivo liver cell component distribution and its carcinogenic potential. Mutation research, 1975, Volume: 30, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Fractionation; Cricetinae; Diet; DNA; Female; Fluorenes; Guinea Pigs; Hydroxyacetylaminofluorene; Liver; Male; Methylcholanthrene; Mutagens; Mutation; Papio; Rats; RNA, Ribosomal; Salmonella typhimurium	1975
Genetic differences in the aromatic hydrocarbon-inducible n-hydroxylation of 2-acetylaminofluorene and acetaminophen-produced hepatotoxicity in mice. Molecular pharmacology, 1975, Volume: 11, Issue:2 Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Enzyme Induction; Fluorenes; Hydrocarbons; In Vitro Techniques; Kinetics; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Molecular Biology	1975
Expression of specific UDP-glucuronosyltransferase isoforms in carcinogen-induced preneoplastic rat liver nodules. Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Glucuronates; Glucuronosyltransferase; Immunoblotting; Immunohistochemistry; Isoenzymes; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Nucleic Acid Hybridization; Precancerous Conditions; Rats; Rats, Inbred Strains; RNA, Messenger	1991
Expression and induction of cytochrome P450 isozymes in hyperplastic nodules of rat liver. Carcinogenesis, 1991, Volume: 12, Issue:11 Topics: 2-Acetylaminofluorene; Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Hyperplasia; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; p-Aminoazobenzene; Rats; Rats, Inbred F344	1991
Prevention of 2-acetylaminofluorene-induced loss of nuclear envelope cytochrome P450 by the simultaneous administration of 3-methylcholanthrene. Biochemical pharmacology, 1991, May-01, Volume: 41, Issue:9 Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Nuclear Envelope; Rats; Rats, Inbred Strains	1991
Kinetics of induction of cytosolic benzaldehyde: NADP and propionaldehyde: NAD aldehyde dehydrogenase activities in rat livers from male Wistar rats. Carcinogenesis, 1991, Volume: 12, Issue:5 Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Enzyme Induction; Glutathione Transferase; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains	1991
Persistently increased expression of a 3-methylcholanthrene-inducible phenol uridine diphosphate-glucuronosyltransferase in rat hepatocyte nodules and hepatocellular carcinomas. Cancer research, 1990, Jun-15, Volume: 50, Issue:12 Topics: 2-Acetylaminofluorene; Animals; Antibodies; Enzyme Induction; Glucuronosyltransferase; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Rats; Rats, Inbred Strains; RNA, Messenger	1990
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay. Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:4 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Dimethylnitrosamine; Lymphoma; Methylcholanthrene; Mice; Microsomes, Liver; Mutagenicity Tests; NADP; Thymidine Kinase; Time Factors; Tumor Cells, Cultured	1990
Effects of hepatocarcinogenic initiators on aldehyde dehydrogenase gene expression in cultured rat hepatic cells. Carcinogenesis, 1990, Volume: 11, Issue:7 Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Diethylnitrosamine; Enzyme Induction; Ethionine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Methylcholanthrene; Rats; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured	1990
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens. Toxicology and applied pharmacology, 1989, Volume: 101, Issue:3 Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Availability; Catechols; DNA; Embryo, Mammalian; Enzyme Induction; Hydroxyacetylaminofluorene; Inactivation, Metabolic; Liver; Methylcholanthrene; Neural Tube Defects; Organ Culture Techniques; Proteins; Rats	1989
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis. Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22 Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac	1989
Induction of rat liver microsomal and nuclear cytochrome P-450 by dietary 2-acetylaminofluorene and butylated hydroxytoluene. Biochemical pharmacology, 1989, Sep-15, Volume: 38, Issue:18 Topics: 2-Acetylaminofluorene; Animals; Antibodies, Monoclonal; Butylated Hydroxytoluene; Cell Nucleus; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Immunoblotting; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains	1989
Influences of different polychlorinated biphenyls on cytocidal, mitoinhibitory, and nodule-selecting activities of N-2-fluorenylacetamide in rat liver. Journal of the National Cancer Institute, 1986, Volume: 76, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Cell Survival; gamma-Glutamyltransferase; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylcholanthrene; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344	1986
Effect of dexamethasone on cytochrome P-450 mediated metabolism of 2-acetylaminofluorene in cultured rat hepatocytes. Biochemical pharmacology, 1987, Jan-15, Volume: 36, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Cells, Cultured; Corticosterone; Cytochrome P-450 Enzyme System; Dexamethasone; Hydrocortisone; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Tyrosine Transaminase	1987
Induction of the aromatic hydrocarbon receptor by trans-4-acetylaminostilbene in rat liver. Comparison with other aromatic amines. Carcinogenesis, 1987, Volume: 8, Issue:7 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Female; Liver; Methylcholanthrene; Mutagens; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; Stilbenes	1987
Induction of liver microsomal epoxide hydrolase, UDP-glucuronyl transferase and cytosolic glutathione transferase in different rodent species by 2-acetylaminofluorene or 3-methylcholanthrene. Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Cricetinae; Cytosol; Enzyme Induction; Epoxide Hydrolases; Female; Glucuronosyltransferase; Guinea Pigs; Male; Mesocricetus; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Rats; Rats, Inbred Strains; Species Specificity	1987
Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons. Carcinogenesis, 1988, Volume: 9, Issue:12 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Arteriosclerosis; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Chickens; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Polycyclic Compounds	1988
Induction of cytochrome P-450 and related drug-metabolizing activities in the livers of different rodent species by 2-acetylaminofluorene or by 3-methylcholanthrene. Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16 Topics: 2-Acetylaminofluorene; 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Guinea Pigs; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Organ Size; Oxidoreductases; Oxygenases; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity	1986
Effects of pretreatment with inducers of hepatic mixed function oxidases on DNA repair elicited by various compounds in hepatocytes from adult and neonatal rats. Cell biology and toxicology, 1987, Volume: 3, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Carcinogens; DDT; DNA Repair; Enzyme Induction; Female; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Rats	1987
Induction of ornithine decarboxylase by aromatic amines in rat liver. Cancer letters, 1987, Volume: 35, Issue:1 Topics: 2-Acetylaminofluorene; Amines; Animals; Carcinogens; Cytosol; Enzyme Induction; Female; Liver; Methylcholanthrene; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Stilbenes; Time Factors	1987
Changes in hepatic dolichol and dolichyl monophosphate caused by treatment of rats with inducers of the endoplasmic reticulum and peroxisomes and during ontogeny. Chemico-biological interactions, 1987, Volume: 62, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Cell Compartmentation; Cholestyramine Resin; Cytochrome P-450 Enzyme System; Diethylamines; Diterpenes; Dolichol Phosphates; Dolichols; Hexosyltransferases; Liver; Liver Regeneration; Methylcholanthrene; Microbodies; Microsomes, Liver; NADH Dehydrogenase; Phenobarbital; Phthalic Acids; Polyisoprenyl Phosphates; Rats; Turpentine	1987
Carbon monoxide inhibits monooxygenation by the conceptus and embryotoxic effects of proteratogens in vitro. Toxicology and applied pharmacology, 1986, Volume: 83, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; In Vitro Techniques; Methylcholanthrene; Oxidation-Reduction; Oxygenases; Pregnancy; Rats; Teratogens	1986
Modulation of cytotoxic and genotoxic effects of 2-acetylaminofluorene in rat and hamster hepatocytes by 3-methylcholanthrene pre-treatment. Carcinogenesis, 1986, Volume: 7, Issue:9 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cells, Cultured; Cricetinae; DNA Repair; Hydroxylation; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylcholanthrene; Mutagens; Rats; Rats, Inbred Strains	1986
Testosterone metabolite profiles reveal differences in the spectrum of cytochrome P-450 isozymes induced by phenobarbitone, 2-acetylaminofluorene and 3-methylcholanthrene in the chick embryo liver. Biochemical pharmacology, 1986, Nov-15, Volume: 35, Issue:22 Topics: 2-Acetylaminofluorene; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; In Vitro Techniques; Isoenzymes; Liver; Methylcholanthrene; Phenobarbital; Testosterone	1986
Use of rodent hepatocytes for metabolic activation in transformation assays. IARC scientific publications, 1985, Volume: 67 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Liver; Methylcholanthrene; Mice; Phenobarbital; Rats; Species Specificity	1985
Identification of the forms of cytochrome P-450 induced in rat liver by 2-acetylaminofluorene using immunoblotting and partial purification. Biochemical and biophysical research communications, 1985, Apr-30, Volume: 128, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Immunosorbent Techniques; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains	1985
Microsomal metabolism of the carcinogen, N-2-fluorenylacetamide, by the mammary gland and liver of female rats. I. Ring- and N-hydroxylations of N-2-fluorenylacetamide. Carcinogenesis, 1985, Volume: 6, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains	1985
A study into the effects of 2-acetylaminofluorene on hepatic monooxygenase activities in the chick embryo. Biochemical pharmacology, 1985, Aug-01, Volume: 34, Issue:15 Topics: 2-Acetylaminofluorene; Acetylation; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Hydroxylation; Liver; Methylcholanthrene; Oxygenases; Phenobarbital	1985
Elevation of hepatic microsomal epoxide hydrolase activity by 2-acetylaminofluorene: role of metabolism. Carcinogenesis, 1985, Volume: 6, Issue:7 Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Epoxide Hydrolases; Kinetics; Methylcholanthrene; Microsomes, Liver; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred F344; Rats, Inbred Strains	1985
Effects of 3-methylcholanthrene and phenobarbital on the capacity of embryos to bioactivate teratogens during organogenesis. Toxicology and applied pharmacology, 1985, Volume: 80, Issue:1 Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; Biotransformation; Cyclophosphamide; Embryo, Mammalian; Female; Male; Methylcholanthrene; Microsomes, Liver; Organ Culture Techniques; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains; Teratogens	1985
Generation of reactive dysmorphogenic intermediates by rat embryos in culture: effects of cytochrome P-450 inducers. Toxicology and applied pharmacology, 1985, Volume: 81, Issue:3 Pt 1 Topics: 2-Acetylaminofluorene; Animals; Aroclors; Biotransformation; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Embryo, Mammalian; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains; Safrole	1985
Inhibitory effect of carbon monoxide on the N- and ring-hydroxylation of 2-acetamidofluorene by hamster hepatic microsomal preparations. The Biochemical journal, 1974, Volume: 144, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Carbon Dioxide; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Fluorenes; Hydroxylation; In Vitro Techniques; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver	1974
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout	1984
Activation of benzo(a)pyrene and 2-acetamidofluorene to mutagens by microsomal preparations from different animal species: role of cytochrome P-450 and P-448. Xenobiotica; the fate of foreign compounds in biological systems, 1981, Volume: 11, Issue:10 Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Female; Guinea Pigs; Male; Mesocricetus; Methylcholanthrene; Mice; Microsomes, Liver; Mutagens; Phenobarbital; Rats; Rats, Inbred Strains	1981
Mixed function oxidase in the mammary gland and liver microsomes of lactating rats. Effects of 3-methylcholanthrene and beta-naphthoflavone. Biochemical pharmacology, 1982, Jan-15, Volume: 31, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Female; Flavonoids; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains	1982
Species differences in the biochemical properties of liver microsomal arylamine and arylamide n-hydroxylases. Chemico-biological interactions, 1982, Volume: 41, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Cricetinae; Fluorenes; Isomerism; Male; Methylcholanthrene; Metyrapone; Mice; Miconazole; Microsomes, Liver; Mixed Function Oxygenases; Paraoxon; Rats; Species Specificity; Substrate Specificity	1982
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats. Biochemical pharmacology, 1983, Nov-15, Volume: 32, Issue:22 Topics: 2-Acetylaminofluorene; Animal Population Groups; Animals; Animals, Suckling; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Female; Flavonoids; Hydroxylation; Lactation; Methylcholanthrene; Microsomes, Liver; Pregnancy; Rats	1983
The effects of phenobarbital, 3-methylcholanthrene and benzo(a)pyrene on the hydrolysis of xenobiotics in the rat. Biochemical pharmacology, 1983, Nov-15, Volume: 32, Issue:22 Topics: 2-Acetylaminofluorene; Acetanilides; Amidohydrolases; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Carboxylic Ester Hydrolases; Female; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Procaine; Rats; Tissue Distribution	1983
Mutagenicity and DNA damage induced by arylamines in the Salmonella/hepatocyte system. Carcinogenesis, 1983, Volume: 4, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Cells, Cultured; DNA; Liver; Methylcholanthrene; Mutagenicity Tests; Mutagens; Mutation; Rats; Salmonella typhimurium; Structure-Activity Relationship	1983
Antibody inhibition of oxidative activation and inactivation of the carcinogen 2-acetylaminofluorene by purified hepatic cytochrome P-450 from 3-methylcholanthrene pretreated rats. Cancer letters, 1983, Volume: 19, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Antibodies; Antigen-Antibody Complex; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Hydroxylation; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Rats, Inbred Strains	1983
Oxidative activation and inactivation of the carcinogen 2-acetylaminofluorene by various purified cytochromes P-450 from 3-methylcholanthrene pretreated rats. Toxicology letters, 1984, Volume: 21, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; Immunodiffusion; Inactivation, Metabolic; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains	1984
The induction of cytochrome P-450 and monooxygenase activities in the chick embryo by 2-acetylaminofluorene. Biochemical and biophysical research communications, 1984, Feb-29, Volume: 119, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Electron Transport; Enzyme Induction; Epoxide Hydrolases; Female; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital	1984
Induction of xenobiotic-metabolizing enzymes by trans-stilbene oxide and 2-acetylaminofluorene: observations on enzyme induction by drugs. Biochemical Society transactions, 1984, Volume: 12, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Enzyme Induction; Enzymes; Liver; Male; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Rats; Stilbenes	1984
Metabolism of 2-acetylaminofluorene by two 3-methylcholanthrene-inducible forms of rat liver cytochrome P-450. Cancer research, 1984, Volume: 44, Issue:9 Topics: 2-Acetylaminofluorene; Animals; Antibodies; Antigen-Antibody Complex; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains	1984
Ring- and N-Hydroxylation of 2-acetylaminofluorene by reconstituted mouse liver microsomal cytochrome P-450 enzyme system. Toxicology letters, 1982, Volume: 11, Issue:1-2 Topics: 2-Acetylaminofluorene; Animals; Cytochrome P-450 Enzyme System; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Species Specificity	1982
Changes in activities of uridine diphosphate-glucuronyltransferases during chemical hepatocarcinogenesis. Gan, 1982, Volume: 73, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxyanisole; Diethylnitrosamine; Enzyme Induction; Glucuronosyltransferase; Hyperplasia; Liver; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; Rats; Rats, Inbred Strains	1982
3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study. Carcinogenesis, 1982, Volume: 3, Issue:9 Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats	1982
Metabolic activation capabilities of S9 liver fraction from 3 species in the L5178Y mouse-lymphoma assay. Mutation research, 1982, Volume: 105, Issue:6 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cricetinae; Leukemia L5178; Leukemia, Experimental; Male; Mesocricetus; Methylcholanthrene; Mice; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity; Thymidine Kinase	1982
Inhibition of 2-acetylaminofluorene oxidations by monoclonal antibodies specific to 3-methylcholanthrene-induced rat liver cytochrome P450. Carcinogenesis, 1983, Volume: 4, Issue:5 Topics: 2-Acetylaminofluorene; Animals; Antibodies, Monoclonal; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Methylcholanthrene; Oxidation-Reduction; Rats	1983
Developmental pattern of 3-methylcholanthrene-inducible mutagenic activation of N-2-fluorenylacetamide, 2-fluorenamine, and 2,4-diaminoanisole in the rabbit. Journal of the National Cancer Institute, 1980, Volume: 64, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Anisoles; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Cytochromes; Fluorenes; Methylcholanthrene; Microsomes, Liver; Mutagens; Phenylenediamines; Rabbits	1980
Activating enzymes: multiple monooxygenase forms with different substrate preferences as related to toxic effects. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 3 Topics: 2-Acetylaminofluorene; Animals; Benzopyrenes; Carcinogens; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Humans; Liver; Male; Methylcholanthrene; Mice; Microsomes, Liver; Mutagens; Oxygenases; Phenobarbital; Rabbits; Rats; Species Specificity; Stereoisomerism; Substrate Specificity	1980
In vivo and in vitro effects of 3-methylcholanthrene on the microsome-mediated in vitro mutagenicity of 2-acetylaminofluorene. Toxicology letters, 1981, Volume: 7, Issue:6 Topics: 2-Acetylaminofluorene; Animals; Cricetinae; Drug Interactions; In Vitro Techniques; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Mutagens; Rats; Salmonella typhimurium; Species Specificity	1981
Genetic differences in the enzymic properties of the aromatic hydrocarbon inducible N-hydroxylation of 2-acetylaminofluorene in mouse liver. Carcinogenesis, 1982, Volume: 3, Issue:11 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Enzyme Induction; Guinea Pigs; Hydroxyacetylaminofluorene; Hydroxylation; Kinetics; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Species Specificity	1982
Stimulation of adrenal cell proliferation in normal rats by carcinogen-induced serum factors. Experimentelle Pathologie, 1980, Volume: 18, Issue:7-8 Topics: 2-Acetylaminofluorene; Adrenal Cortex; Animals; Circadian Rhythm; Male; Methylcholanthrene; Mitogens; Mitosis; Mitotic Index; Rats	1980
The suppressive effect of hepatic 9,000 x G supernatant fraction from 3-methylcholanthrene-treated rats on the mutagenic activity of 2-acetylaminofluorene. Japanese journal of pharmacology, 1980, Volume: 30, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; Drug Synergism; Flavonoids; Liver; Male; Methylcholanthrene; Mutagens; Phenobarbital; Rats; Subcellular Fractions	1980
Specific labelling of microsomal proteins by reactive intermediates generated from 2-acetylaminofluorene in vitro. Chemico-biological interactions, 1981, Volume: 36, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cytosol; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains	1981
Reactive intermediates of 2-acetylaminofluorene metabolism in vitro covalently label specific rat liver microsomal proteins. Advances in experimental medicine and biology, 1981, Volume: 136 Pt B Topics: 2-Acetylaminofluorene; Animals; Carbon Radioisotopes; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats	1981
Competitive inhibitory effect of microsomal N-hydroxylase, a possible explanation for the in vivo in inhibition of 2-acetylaminofluorene carcinogenicity by 3-methylcholanthrene. Toxicology letters, 1980, Volume: 5, Issue:1 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cricetinae; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Rats; Species Specificity	1980
Characterization of the guinea pig liver microsomal 2-fluorenylamine and N-2-fluorenylacetamide N-hydroxylase. Cancer letters, 1980, Volume: 9, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carcinogens; Fluorenes; Guinea Pigs; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Paraoxon; Sodium Fluoride	1980
Induction, activation, and inhibition of hamster and rat liver microsomal arylamide and arylamine N-hydroxylase. Cancer research, 1980, Volume: 40, Issue:10 Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cricetinae; Enzyme Activation; Enzyme Induction; Kinetics; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Paraoxon; Rats	1980
Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test. Mutation research, 1993, Volume: 290, Issue:2 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Amines; Animals; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; DNA Repair; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Fluorenes; Genes, Insect; Larva; Male; Methylcholanthrene; Mutagens; Polycyclic Compounds; Pyrenes; Sex Ratio	1993
Procedure for reduction of test chemical requirement in preliminary assays using the L5178Y TK+/- mouse lymphoma forward mutation assay. Environmental and molecular mutagenesis, 1994, Volume: 23, Issue:2 Topics: 2-Acetylaminofluorene; Animals; Dose-Response Relationship, Drug; Ethanol; Ethyl Methanesulfonate; Fluorenes; Liver Extracts; Methylcholanthrene; Mice; Mutagenicity Tests; Rats; Tumor Cells, Cultured	1994
Metabolism of 2-acetylaminofluorene. I. Metabolism in vitro of 2-acetylaminofluorene and 2-acetylaminofluoren-9-one by hepatic enzymes. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cytosol; Female; Hydroxylation; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rabbits; Rats; Rats, Sprague-Dawley; Stimulation, Chemical	1993
Alterations in epidermal growth factor binding to hepatic membranes following dietary exposure of rats to known hepatocarcinogens. Toxicology letters, 1997, Mar-14, Volume: 91, Issue:1 Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aniline Compounds; Animals; Benzidines; Binding Sites; Carcinogens; Epidermal Growth Factor; Ethionine; Fluorenes; Food Deprivation; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thioacetamide	1997
Induced drug resistance inhibits selection of initiated cells and cancer development. Carcinogenesis, 1997, Volume: 18, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Liver; Liver Regeneration; Male; Methylcholanthrene; Organ Size; Phenobarbital; Rats; Rats, Wistar	1997
[Inhibition of 2-acetylaminofluorene tumors in rats with simultaneously fed 20-methylcholanthrene, 9:10-dimethyl-1:2-benzanthracene and chrysene, and consideration of sex difference in tumor genesis with 2-acetyl-aminoflurene]. Gan, 1953, Volume: 44, Issue:2-3 Topics: 2-Acetylaminofluorene; Animals; Benz(a)Anthracenes; Carcinogens; Chrysenes; Fluorenes; Gonadal Steroid Hormones; Methylcholanthrene; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Rats; Sex Characteristics	1953
The hydroxylation of the carcinogen 2-acetylaminofluorene by rat liver: stimulation by pretreatment in vivo with 3-methylcholanthrene. The Journal of biological chemistry, 1960, Volume: 235 Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Fluorenes; Hydroxylation; Liver; Methylcholanthrene; Rats	1960
Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens. Archives of toxicology, 2004, Volume: 78, Issue:10 Topics: 2-Acetylaminofluorene; Animal Testing Alternatives; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Enzymes; Female; Liver; Methylcholanthrene; Methylenebis(chloroaniline); Phenobarbital; Phosphorus Radioisotopes; Quinoxalines; Rats; Rats, Inbred F344; Rats, Wistar; Turkey	2004
Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:1 Topics: 2-Acetylaminofluorene; Animals; BALB 3T3 Cells; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Computational Biology; Gene Expression Regulation, Neoplastic; Methylcholanthrene; Mice; Phenylenediamines; Principal Component Analysis; RNA, Messenger; Toxicogenetics	2010